Prescription onlyLower-cost generic availableClass: Musculoskeletal

Evista Alternatives

(raloxifene)

Prescription onlyLower-cost generic availableClass: Musculoskeletal
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Compare Evista (raloxifene) to alternatives

These medications are comparable to Evista (raloxifene) or used for similar purposes.

Evista
(raloxifene)

Actonel
(risedronate)

Boniva
(ibandronate)

Fosamax
(alendronate)

Forteo
(teriparatide)

Prevents bone loss and lowers your risk of breast cancer. Evista (Raloxifene) is effective at reducing bone loss and lowering the risk of breast cancer in postmenopausal women, but does carry the risk of blood clots.Prevents bone loss. Actonel (risedronate) is a first-choice treatment for osteoporosis and is available as a generic, but taking it can be a hassle.Prevents bone loss. Boniva (ibandronate) is a first-choice treatment for osteoporosis and is available as a generic, but how you have to take it can be a hassle. It's also only approved for women, not men.Prevents bone loss. Fosamax (alendronate) is a first-choice treatment for osteoporosis, but taking it can be a hassle.Prevents bone loss. Forteo (Teriparatide) is a good second-choice medication to treat bone loss, but it's only available as an injectable.
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Best available price for 30 (60mg) tablets of raloxifene
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Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
Reviews for Evista (raloxifene)
Not enough review data. Review it!
of people (All ages) say Evista (raloxifene) is worth it
Not enough review data. Review it!
say it works well
Not enough review data. Review it!
say it's a big hassle
Have you used Evista (raloxifene)?
Worth itNot sureNot worth it
Reviews for Actonel (risedronate)
36%
-64% worse vs. Evista (raloxifene)
19%
-81% worse vs. Evista (raloxifene)
25%
-25% worse vs. Evista (raloxifene)
Have you used Actonel (risedronate)?
Worth itNot sureNot worth it
Reviews for Boniva (ibandronate)
31%
-69% worse vs. Evista (raloxifene)
20%
-80% worse vs. Evista (raloxifene)
27%
-27% worse vs. Evista (raloxifene)
Have you used Boniva (ibandronate)?
Worth itNot sureNot worth it
Reviews for Fosamax (alendronate)
43%
-57% worse vs. Evista (raloxifene)
30%
-70% worse vs. Evista (raloxifene)
19%
-19% worse vs. Evista (raloxifene)
169 reviews
Have you used Fosamax (alendronate)?
Worth itNot sureNot worth it
Reviews for Forteo (teriparatide)
Not enough review data. Review it!
-20% worse vs. Evista (raloxifene)
Not enough review data. Review it!
-40% worse vs. Evista (raloxifene)
Not enough review data. Review it!
-40% worse vs. Evista (raloxifene)
Have you used Forteo (teriparatide)?
Worth itNot sureNot worth it
Side effects
EvistaActonelBonivaFosamaxForteo
  • Joint pain 2%
  • Flu syndrome 3%
  • Any side effect 2%
  • Hot flashes 4%
  • Bronchitis 1%
More Evista side effects »
  • Infection 1%
  • Back pain 2%
  • Joint pain 2%
  • Stomach pain 2%
  • Traumatic bone fracture 3%
  • High blood pressure 1%
More Actonel side effects »
  • Abdominal pain 8%
  • High blood pressure 6%
  • Joint pain 6%
  • Indigestion 6%
  • Diarrhea 5%
  • Back pain 5%
  • Nausea 5%
  • Constipation 4%
  • Cold 4%
  • Pain in arms or legs 4%
More Boniva side effects »
  • Abdominal pain 2%
  • Bone, muscle or joint pain 1%
  • Diarrhea 1%
  • Gas 2%
  • Headache 1%
  • Constipation 1%
  • Ulcer in esophagus 2%
More Fosamax side effects »
  • Inflammation inside the nose 1%
  • Joint pain 2%
  • Muscle weakness 2%
  • Nausea 2%
  • Dizziness 3%
  • Headache 1%
  • Any side effect 1%
  • Sore throat 1%
More Forteo side effects »
How it works
EvistaActonelBonivaFosamaxForteo
Evista (Raloxifene) is a selective estrogen receptor modulator (SERM). It acts like estrogen to make your bones stronger and less likely to break, and also protects breast and uterus tissues from other estrogen effects.Actonel (risedronate) is a bisphosphonate. It slows down osteoclasts, which are the cells that break down bone. This results in greater bone mass, and lowers the possibility of fractures.Boniva (ibandronate) is a bisphosphonate. It slows down osteoclasts, the cells that break down bone. This results in greater bone mass and lowers the possibility of fractures.Fosamax (alendronate) is a bisphosphonate, which inhibits bone breakdown.Forteo (Teriparatide) works by stimulating cells that build up and strengthen your bones.
Type of medication
EvistaActonelBonivaFosamaxForteo
Prescription only
Prescription only
Prescription only
Prescription only
Prescription only
Available as
EvistaActonelBonivaFosamaxForteo
  • Pill
  • Pill
  • Pill
  • Injection
  • Pill
  • Effervescent tablet
  • Liquid
  • Injection
Used for
EvistaActonelBonivaFosamaxForteo
Risk factors for serious side effects
EvistaActonelBonivaFosamaxForteo
  • History of stroke
  • Heart and blood vessel problems
  • History of mini stroke (TIA)
  • Atrial fibrillation
  • Smoking
Detailed Evista (raloxifene) risks & warnings »
  • History of ulcers, or other stomach or esophageal problems
  • History of difficulty swallowing
  • Unable to sit upright or stand for 30 minutes after taking the medicine
  • Oral or dental surgery
  • Cancer
Detailed Actonel (risedronate) risks & warnings »
  • Taking with aspirin or other NSAIDS (nonsteroidal anti-inflammatory drugs)
  • History of ulcers, or other stomach or esophageal problems
  • History of difficulty swallowing
  • Unable to sit upright or stand for 60 minutes after taking the medicine
  • Oral or dental surgery
Detailed Boniva (ibandronate) risks & warnings »
  • Taking anti-inflammatory medicines like ibuprofen, and naproxen
  • History of ulcers or stomach or esophageal conditions
  • Difficulty swallowing
  • Problems sitting or standing for at least 30 minutes
  • Oral or dental surgery
Detailed Fosamax (alendronate) risks & warnings »
  • Paget's bone disease
  • Young people with open epiphyses
  • Hypercalcemia
  • Hyperparathyroidism
  • History of kidney stones
Detailed Forteo (teriparatide) risks & warnings »
Pregnancy

Research studies with real people or animals found harmful effects on unborn babies. If you’re pregnant, the risks to your unborn baby outweigh the benefits.

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Alcohol
EvistaActonelBonivaFosamaxForteo
  • Regular exercise, cutting back on smoking, and drinking less alcohol can also reduce your risk of bone loss.
No alcohol related info.No alcohol related info.No alcohol related info.No alcohol related info.
Food
EvistaActonelBonivaFosamaxForteo
  • Take 1 tablet daily with or without food about the same time each day. It’s important to read the information you get with your medicine about how to take Evista (Raloxifene).
  • Although rare, breakdown of the jawbone has happened in people taking Actonel (risedronate). This is more likely to happen if you have oral or dental surgery, or if you have poor oral hygiene. If you notice pain or swelling in your jaw, talk to your doctor right away. Also, tell your surgeon that you are taking Actonel (risedronate) prior to any oral/dental procedures.
  • Although rare, breakdown of the jawbone has happened in people taking Boniva (ibandronate). This is more likely to happen if you have oral or dental surgery, or if you have poor oral hygiene. The risk might also increase the longer you take Boniva (ibandronate). If you notice pain or swelling in your jaw, talk to your doctor right away.
No food related info.No food related info.
Kidneys and liver
EvistaActonelBonivaFosamaxForteo
  • Evista (Raloxifene) is processed by the kidney and liver. If you have kidney or liver problems, talk to your doctor because you may need a different dose.
No kidneys and liver related info.No kidneys and liver related info.No kidneys and liver related info.
  • Forteo (Teriparatide) can cause kidney stones, especially if you have high calcium levels in your urine. If kidney stones are suspected, your doctor can measure the amount of calcium in your urine to see if you are at risk. Be careful using this medication if you have a history of kidney stones.
Pain
EvistaActonelBonivaFosamaxForteo
No pain related info.
  • Talk to your doctor if you have pain with swallowing, pain in your chest or stomach, or new or worsening heartburn.
  • If you have pain with swallowing around your chest or stomach, new or worsening heartburn, or any pain around your hips, thighs, or jaw, tell your doctor right away.
  • Fosamax (alendronate) can cause bone and muscle pain. However, this is very rare. Stop taking the medication and talk to your doctor if this happens to you.
  • Fosamax (alendronate) can cause fractures in the legs as a result of little or no force. This is rare. If you notice a new dull or aching pain in your hips or thighs, talk to your doctor right away.
No pain related info.
Upsides and benefits
EvistaActonelBonivaFosamaxForteo
  • Evista (Raloxifene) doesn’t affect the breast or uterus the same way that estrogen does, so the risk of cancer is much lower.
  • Taking Evista (Raloxifene) with calcium and vitamin D improves spine and hip bone health and lowers the risk of fractures.
  • Lowers total cholesterol and low-density lipoprotein (LDL) cholesterol (the bad cholesterol).
  • Actonel (risedronate) is one of the first choice medicines to treat osteoporosis.
  • It is available in generic.
  • It is available in tablets that can be taken by mouth once or twice a month, once a week, or once a day.
  • Available in generic.
  • Available in pills that can be taken by mouth once a month.
  • Also available as a shot given into your vein every 3 months.
  • First choice to treat osteoporosis
  • Lowers your risk of fractures due to osteoporosis.
  • Available generic.
  • Available as daily, weekly, or twice weekly dosing.
  • Comes as a regular tablet, an oral solution, or effervescent tablet.
  • If you're unable to use bisphosphonates or are still having fractures despite being on other medications, Forteo (Teriparatide) can be a good alternative.
  • You can start using Forteo (Teriparatide) as soon as you stop using bisphosphonates.
Downsides and risks
EvistaActonelBonivaFosamaxForteo
  • Can only take Evista (Raloxifene) once you’re in menopause. You can't take it if you're pregnant or breastfeeding.
  • Evista (Raloxifene) isn’t as effective as tamoxifen at lowering the risk of invasive breast cancer.
  • Shouldn’t take it with any other forms of estrogen (pills, patches, or injection).
  • It doesn’t increase bone strength as much as estrogen does and isn’t effective for treating hot flashes.
  • You have to take Actonel (risedronate) first thing in the morning with a full glass of water.
  • You have to remain upright for at least 30 minutes after you take it, which can be a problem if you have trouble moving.
  • You have to take Boniva (ibandronate) first thing in the morning with a full glass of water.
  • You have to remain upright for at least 60 minutes after you take the medicine, which can be a problem if you have mobility issues.
  • It is only approved to treat and prevent osteoporosis in women who have gone through menopause.
  • Can harm your esophagus if you don't remain upright for 30 minutes after taking it.
  • Not recommended for people who can't sit or stand upright for at least 30 minutes.
  • Can increase the risk of atypical fractures.
  • Can cause bad heartburn or stomach problems.
  • Only available as a brand medication, so it can be expensive.
  • You have to inject this every day, so it may not be a good option if you don't like needles.
  • Shouldn't take this longer than 18 to 24 months since it can increase the risk of bone cancers.
Tips from our pharmacists for people taking the medication
EvistaActonelBonivaFosamaxForteo
  • Take 1 tablet daily with or without food about the same time each day. It’s important to read the information you get with your medicine about how to take Evista (Raloxifene).
  • Your doctor may tell you to take calcium and vitamin D with Evista (Raloxifene) to prevent osteoporosis (bone thinning and loss), especially if you don’t get enough in your diet.
  • Regular exercise, cutting back on smoking, and drinking less alcohol can also reduce your risk of bone loss.
  • If you're taking the immediate release medicine, take it first thing when you wake up by swallowing the whole pill with a full glass of water.
  • Remain sitting or standing, and don't take any other medications, vitamins, or supplements for at least 30 minutes after you take Actonel (risedronate).
  • If you forget to take your dose, skip it and take it the following morning.
  • Keep taking your calcium and vitamin D.
  • Talk to your doctor if you have pain with swallowing, pain in your chest or stomach, or new or worsening heartburn.
  • If you develop pain in your jaw, hips, or thighs, call your doctor.
  • Can be taken as a pill or as an injection.
  • Take the pill first thing when you wake up by swallowing the whole pill with a full glass of plain water.
  • Don't eat or drink anything, or take other medicines for at least 60 minutes after you've taken the pill.
  • Stay sitting or standing for at least 60 minutes after you take the pill.
  • If you have pain with swallowing around your chest or stomach, new or worsening heartburn, or any pain around your hips, thighs, or jaw, tell your doctor right away.
  • Take the 150 mg tablet on the same day every month. If you forget to take the 150 mg tablet on your chosen day each month, take it on the next day in the morning.
  • Keep taking your calcium and vitamin D.
  • Take first thing in the morning with a full glass of water.
  • Avoid eating or drinking for 30 minutes after taking Fosamax (alendronate).
  • Remain upright for 30 minutes after taking Fosamax (alendronate).
  • Talk to your doctor if you develop pain around jaw, throat, chest, abdomen, hips or thighs.
  • Let your doctor know if you have any major dental procedures coming up. You may need to temporarily stop taking Fosamax (alendronate).
  • Dissolve the effervescent tablet in 4 ounces of plain water. When solution stops fizzing, wait 5 minutes before stirring for 10 seconds and drinking.
  • You should be sitting or lying down when you inject Forteo (Teriparatide) since it can make you dizzy.
  • You should inject Forteo (Teriparatide) under the skin in either your thigh or stomach.
  • Make sure the liquid in the vial of Forteo (Teriparatide) is clear and colorless before you inject it. Don't use it if it looks cloudy, colored, or if you see particles inside.
Learn more
More about EvistaSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Evista (raloxifene)?
Worth itNot sureNot worth it
More about ActonelSide effectsReviews & ratingsFDA package insert
Have you used Actonel (risedronate)?
Worth itNot sureNot worth it
More about BonivaSide effectsReviews & ratingsFDA package insert
Have you used Boniva (ibandronate)?
Worth itNot sureNot worth it
More about FosamaxSide effectsReviews & ratingsFDA package insert
Have you used Fosamax (alendronate)?
Worth itNot sureNot worth it
More about ForteoSide effectsReviews & ratingsFDA package insert
Have you used Forteo (teriparatide)?
Worth itNot sureNot worth it