Prescription onlyNo lower cost generic available

Femring

(Estradiol Acetate Vaginal Ring)

  • Vaginal ring
  • Hot flashes and night sweats
  • Vaginal dryness and inflammation
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Relieves hot flashes and vaginal dryness due to menopause.

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Prescription onlyNo lower cost generic available

Our pharmacists’ bottom line

Femring (Estradiol Acetate Vaginal Ring) is a vaginal ring that may be less of a hassle than estrogen pills, gels, patches, or vaginal creams, but comes with the same side effects.

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  • Femring (Estradiol Acetate Vaginal Ring) relieves vaginal dryness and irritation to make sex more enjoyable.
  • Works locally in the vagina and doesn't expose the rest of your body to estrogen like pills do.
  • Good option for people who don't want to take oral pills.
  • Generally works well with fewer side effects.
  • Many women think Femring (Estradiol Acetate Vaginal Ring) is easy to insert and comfortable to use.
  • In a 12-week study, Femring (Estradiol Acetate Vaginal Ring) worked well to improve vaginal problems, reduced pain during urination, and sudden urges to urinate.
  • Femring (Estradiol Acetate Vaginal Ring) slowly releases estrogen over the 90 days the ring is in place, so you only have to remove and insert a new one every three months.
  • Femring (Estradiol Acetate Vaginal Ring) may not be the best estrogen product if you have a narrow vagina or frequent vaginal infections.
  • The ring can fall out without you noticing it.
  • Increases your risk of endometrial (uterine cancer).
  • If you have your uterus, you might need to use Femring (Estradiol Acetate Vaginal Ring) with another hormone called progestin to lower your risk of uterine cancer.
  • Can be expensive since it's only available as a brand name product.

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Side effects for Femring (Estradiol Acetate Vaginal Ring)

From clinical trials of Femring / Postmenopausal estrogen replacement (0.05 mg/day) ( 221)

  • Vaginal bleeding between periodsVaginal bleeding between periods8% for Femring vs.2% for placebo
  • HeadacheHeadache7% for Femring vs.9% for placebo
  • Abdominal distensionAbdominal distension7% for Femring vs.3% for placebo
  • Vaginal candidiasisVaginal candidiasis6% for Femring vs.3% for placebo
  • Breast tendernessBreast tenderness6% for Femring vs.2% for placebo
  • Back painBack pain6% for Femring vs.4% for placebo
  • Sinus inflammationSinus inflammation2% for Femring vs.2% for placebo
  • Uterine painUterine pain2% for Femring vs.1% for placebo
  • Urinary tract infectionUrinary tract infection1% for Femring vs.2% for placebo

What to expect when you take Femring (Estradiol Acetate Vaginal Ring)

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Tips from our pharmacists
  • Insert the ring as deeply as possible into your vagina. You shouldn't feel the ring once it's inserted.
  • The ring is good for 90 days in your vagina. If it falls out before the 90 days are up, just clean it with warm water and reinsert.
  • You don’t have to remove Femring (Estradiol Acetate Vaginal Ring) to treat a vaginal infection or have sex.
  • It can take up to 2 to 3 weeks to feel the full benefits.
  • Most people don't have many side effects, but temporary nausea, dizziness, bloating, and breast tenderness are possible.
  • Tell your doctor about any unusual vaginal bleeding.

Risks and Warnings for Femring (Estradiol Acetate Vaginal Ring)

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    • Higher risk if:
    • Using estrogen for more than one year

    Vaginal bleeding after menopause can be a warning sign of uterus (endometrial) cancer, so let your doctor know if you notice any unusual bleeding. When estrogen is prescribed to women after menopause who still have a uterus, progestin should be used with it to lower the risk of cancer. Low-dose vaginal estrogen products are often a better choice than oral pills for women 65 years or older who have vaginal symptoms.

    This is a black box warning. The FDA requires this warning when there is a significant risk of serious or life-threatening effects that anyone taking the drug should consider.

Means that some groups have a high risk of experiencing this side effect

Tips from pharmacists and people taking Femring (Estradiol Acetate Vaginal Ring)

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The FDA category for this medication is X. It is advised that you: Unsafe
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Sex
  • Upsides and downsides from our pharmacists
  • Femring (Estradiol Acetate Vaginal Ring) relieves vaginal dryness and irritation to make sex more enjoyable.
  • Tips from our pharmacists
  • You don’t have to remove Femring (Estradiol Acetate Vaginal Ring) to treat a vaginal infection or have sex.