Prescription onlyLower-cost generic availableClass: Musculoskeletal



Prescription onlyLower-cost generic availableClass: Musculoskeletal
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Relaxes your muscles.

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Our bottom line

Flexeril (Cyclobenzaprine) is widely used to treat muscle spasms and is available as a generic, but it shouldn't be used long-term.

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  • Can relieve pain associated with muscle spasms.
  • Available as a generic medication.
  • Can be used by pregnant women.
People say this drug is:
1064 reviews


  • Can cause dizziness and sleepiness.
  • Not meant for long-term therapy.
  • Not recommended in elderly patients, people with glaucoma, or in people with recent heart issues (like rhythm problems, heart failure, or heart attack).
How it works

Flexeril (Cyclobenzaprine) is a muscle relaxer. It works in the brain to help calm down muscle spasms without interfering with normal muscle function.

What to expect when you take Flexeril (cyclobenzaprine) for Muscle relaxant

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Side effect rates for Flexeril (cyclobenzaprine)

255 From clinical trials of Flexeril / Muscle spasms (Extended release - 15 mg)
  • Dry mouth
  • Dizziness
  • Fatigue
  • Nausea

Risks and Warnings for Flexeril (cyclobenzaprine)

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    • Higher risk if:
    • Taking monoamine oxidase inhibitors (MAOI) 14 days before starting
    • Taking other medications for your mood

    Taking Flexeril (Cyclobenzaprine) along with other medications used for your mood, such as monoamine oxidase inhibitors and certain antidepressants, can make you more likely to have a serious condition called serotonin syndrome. Symptoms include sudden changes in your mental status (confusion and hallucinations), muscles (tremors and rigidity) and nausea, vomiting and diarrhea. Go to the emergency room or talk to your doctor immediately if you notice these symptoms. Talk to your doctor or pharmacist if you are unsure if your other medications will interact with Flexeril (Cyclobenzaprine).

Common concerns from people taking Flexeril (cyclobenzaprine)

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  • Don't drink alcohol while on this medication.
  • Can relieve pain associated with muscle spasms.
  • Taking Flexeril (Cyclobenzaprine) may make you feel dizzy or sleepy for the first few days, especially if you drink a lot of alcohol or take recreational drugs. Your body should adjust to this, however, avoid driving or other activities requiring concentration until you know how your body responds to the medication. Talk to your doctor or pharmacist if these symptoms bother you.
  • I was only able to take it at night, since it made me drowsy. I wouldn't drive for sure.
  • 5mg dosages are similar in effectiveness and don't cause as much drowsiness or dry mouth. While only the dry mouth was an issue for me after the first week it would have been nice to know that I could have started at a lower dose.
  • it will make you sleepy. I have not noticed any other side effects.
  • caused dry mouth and weight gain