Prescription or OTCLower-cost generic available



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Relieves allergy symptoms.

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Prescription or OTCLower-cost generic available

Our bottom line

Flonase (Fluticasone) is a good first-choice medicine for treating a runny or stuffy nose caused by allergies, and it's cheaper than some alternatives.


  • First-choice medication for treating runny and stuffy noses caused by allergies. It works by reducing inflammation in the nose.
  • Because it's used directly where the inflammation is happening, it has fewer side effects than oral steroids do and has a lower chance of causing withdrawal symptoms once the medication is stopped.
  • Can be used as needed to help control symptoms in people age 13 years or older.
  • Available as a generic medication.
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  • Flonase (Fluticasone) doesn't have a counter on it, so it can be hard to remember how many sprays are left (each bottle has 120 sprays).
  • Needs to be primed (pressed/pumped until a fine spray appears) up to six times prior to using it for the first time, or if you haven't used it in 2 weeks.
  • Since the medicine in Flonase (Fluticasone) is a steroid, it can slow down your healing process if you've hurt your nose or had nose surgery.
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What to expect when you take Flonase (Fluticasone) for Nasal decongestant

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Tips from our pharmacists
  • It can take several days for Flonase (Fluticasone) to start working fully.
  • Don't take more of it than was prescribed for you.
  • Blow your nose before using Flonase (Fluticasone).
  • Can cause thrush (a fungal infection) inside the nose and throat.
  • Can also cause a headache, sore throat, or nosebleeds.
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Side effects for Flonase (Fluticasone)

Manufacturers don’t say how common these side effects are

  • Alteration of taste or smell
  • Blurred vision
  • Clouded eye lens
  • Conjuctivitis
  • Cough
  • Eye dryness and irritation
  • Glaucoma
  • Hoarseness
  • Hypersensitivity reactions
  • Increased intraocular pressure
  • Nasal ulcer
  • Sore throat
  • Throat irritation and dryness
  • Voice changes

Risks and Warnings for Flonase (Fluticasone)

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    • Higher risk if:
    • Switching from oral or injectable steroids to inhaled, especially if used long term
    • Using other inhaled steroids with Flonase (Fluticasone)

    Switching from oral or injectable steroids to inhaled, especially if used for an extended amount of time, can cause withdrawal symptoms, including joint or muscle pain, lack of energy and depression. This can be worsened if you are under stress or if the change in steroid dose happens too quickly. Your doctor will work with you if this is a concern.

Means that some groups have a high risk of experiencing this side effect

Tips from pharmacists and people taking Flonase (Fluticasone)

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The FDA category for this medication is C. It is advised that you: Weigh risks vs. benefits
  • use it right before bed instead of in the you will have maximum dose to keep you breathing well thoughout the night so you get the best nights sleep