Prescription onlyLower-cost generic availableClass: Mental health



Prescription onlyLower-cost generic availableClass: Mental health
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Helps control your thoughts and mood.

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Our bottom line

Geodon (Ziprasidone) treats bipolar disorder and schizophrenia, and causes fewer side effects than similar medicines. It’s not a good choice if you have heart problems.

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Prices and coupons for 30 (40mg) capsules of ziprasidone


  • Geodon (Ziprasidone) can be used with lithium or valproate to better treat bipolar disorder.
  • Geodon (Ziprasidone) can treat agitation in people with schizophrenia by reducing symptoms of anxiety, nervousness, and distress.
  • Compared to other antipsychotics, it has a lower risk of weight gain, hyperglycemia, and hyperlipidemia.
  • The Geodon (Ziprasidone) capsule is available as a generic.
  • The injectable form can treat sudden agitation in schizophrenia when it's not possible to use the capsules.
  • It's available as a pill that you take by mouth daily for continuous treatment and as an injection used for short-term treatment of agitation.
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  • Elderly people with dementia shouldn’t take Geodon (Ziprasidone).
  • You shouldn’t take Geodon (Ziprasidone) if you have a history of heart problems (slow heart rate, recent heart attack, heart failure, or heart rhythm problems). It’s also not safe to take if you have low potassium or magnesium, or are taking medicines that increase the risk of this happening (diuretics).
  • You'll need to get blood tests before you start taking Geodon (Ziprasidone).
  • It causes slightly less weight gain than similar medicines.
  • Can't take Geodon (Ziprasidone) capsules and injections at the same time. Capsules should be used instead of the injection as soon as possible.
How it works

Geodon (Ziprasidone) is a second generation antipsychotic. It treats schizophrenia and bipolar disorder by adjusting the levels of dopamine and serotonin in your brain, which affects thoughts and mood.

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Side effect rates for Geodon (ziprasidone)

92 From clinical trials of Geodon / Acute agitation in schizophrenia (2 mg)
  • Injection site pain
  • Drowsiness
  • Nausea
  • Dizziness
  • Headache
  • Diarrhea
  • Sleep difficulty
  • Anxiety
  • High blood pressure
  • Muscle weakness

Risks and Warnings for Geodon (ziprasidone)

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    • Higher risk if:
    • Elderly patients with dementia

    Older patients with dementia-related psychosis have a higher risk of death when treated with antipsychotic medications. Geodon (Ziprasidone) is not approved to treat dementia-related psychosis.

    This is a black box warning. The FDA requires this warning when there is a significant risk of serious or life-threatening effects that anyone taking the drug should consider.

Means that some groups have a high risk of experiencing this side effect

Common concerns from people taking Geodon (ziprasidone)

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  • worked perfectly for bipolar/psychosis however i was severely nauseous because i didn't take it with meals. be sure to eat enough with it and drink plenty of water (might make urine green). found it harder to get up in the morning/go to work because i was taking higher doses at night so i felt less groggy in the day. restlessness was bothersome. might go back on it because less weight gain than seroquel. probably the best injectable antipsychotic, worth cost.
  • Can cause drowsiness when you first start taking it, so avoid activities that require you to be alert until you know how it affects you.
  • It causes slightly less weight gain than similar medicines.