Prescription onlyLower-cost generic available



Back to: Full Site NavigationSkip to: side effects sectionSkip to: What to expect sectionSkip to: Risks and warnings sectionSkip to: Tips from users and pharmacists

Helps control your thoughts and mood.

Skip Upsides & Downsides section. Skip to side effects section.
Prescription onlyLower-cost generic available

Our pharmacists’ bottom line

Geodon (Ziprasidone) treats bipolar disorder and schizophrenia, and causes fewer side effects than similar medicines. It’s not a good choice if you have heart problems.

  • Geodon (Ziprasidone) can be used with lithium or valproate to better treat bipolar disorder.
  • Geodon (Ziprasidone) can treat agitation in people with schizophrenia by reducing symptoms of anxiety, nervousness, and distress.
  • Compared to other antipsychotics, it has a lower risk of weight gain, hyperglycemia, and hyperlipidemia.
  • The Geodon (Ziprasidone) capsule is available as a generic.
  • The injectable form can treat sudden agitation in schizophrenia when it's not possible to use the capsules.
  • It's available as a pill that you take by mouth daily for continuous treatment and as an injection used for short-term treatment of agitation.
  • Elderly people with dementia shouldn’t take Geodon (Ziprasidone).
  • You shouldn’t take Geodon (Ziprasidone) if you have a history of heart problems (slow heart rate, recent heart attack, heart failure, or heart rhythm problems). It’s also not safe to take if you have low potassium or magnesium, or are taking medicines that increase the risk of this happening (diuretics).
  • You'll need to get blood tests before you start taking Geodon (Ziprasidone).
  • It causes slightly less weight gain than similar medicines.
  • Can't take Geodon (Ziprasidone) capsules and injections at the same time. Capsules should be used instead of the injection as soon as possible.

Save on your next Geodon (Ziprasidone) prescription

Be sure you’re getting the lowest price for your medication, even if you have insurance.

Skip side effects sections. Skip to What to Expect and Pharmacists Tips section.

Side effects for Geodon (Ziprasidone)

From clinical trials of Geodon / Acute agitation in schizophrenia (2 mg) ( 92)

  • Injection site painInjection site pain9% for Geodon vs.0% for placebo
  • DrowsinessDrowsiness8% for Geodon vs.0% for placebo
  • NauseaNausea4% for Geodon vs.0% for placebo
  • DizzinessDizziness3% for Geodon vs.0% for placebo
  • DiarrheaDiarrhea3% for Geodon vs.0% for placebo
  • HeadacheHeadache3% for Geodon vs.0% for placebo
  • Sleep difficultySleep difficulty3% for Geodon vs.0% for placebo
  • AnxietyAnxiety2% for Geodon vs.0% for placebo
  • Muscle weaknessMuscle weakness2% for Geodon vs.0% for placebo
  • High blood pressureHigh blood pressure2% for Geodon vs.0% for placebo

Manufacturers don’t say how common these side effects are

  • Abdominal pain
  • Abnormal speech
  • Abnormally slow heartbeat
  • Constipation
  • Furunculosis
  • Loss of appetite
  • Menstrual cramps
  • Personality disorder
  • Positional low blood pressure
  • Rectal hemorrhage
  • Restlessness
  • Sweating
  • Tingling sensation
  • Vomiting

What to expect when you start Geodon (Ziprasidone)

Skip what to expect section. Skip to Risks & Warnings section.
Tips from our pharmacists
  • It usually takes 4 to 6 weeks to see the full effects, so hang in there and wait until it works to figure out the right dose for you.
  • Take Geodon (Ziprasidone) twice a day, preferably with food.
  • Can cause drowsiness when you first start taking it, so avoid activities that require you to be alert until you know how it affects you.
  • Geodon (Ziprasidone) can cause heart problems, so call your doctor right away if you faint or feel a change in your heartbeat.
  • Let your doctor know if you're taking a diuretic (water pill) or have a condition like chronic diarrhea that'll lower the amount of potassium or magnesium in your blood.

Risks and Warnings for Geodon (Ziprasidone)

Skip Risks and Warnings section. Skip to Tips section.
    • Higher risk if:
    • Elderly patients with dementia

    Older patients with dementia-related psychosis have a higher risk of death when treated with antipsychotic medications. Geodon (Ziprasidone) is not approved to treat dementia-related psychosis.

    This is a black box warning. The FDA requires this warning when there is a significant risk of serious or life-threatening effects that anyone taking the drug should consider.

Means that some groups have a high risk of experiencing this side effect

Tips from pharmacists and people taking Geodon (Ziprasidone)

Final section. Do you want to return to drug navigation?
The FDA category for this medication is C. It is advised that you: Weigh risks vs. benefits
  • Tips from our pharmacists
  • Take Geodon (Ziprasidone) twice a day, preferably with food.
  • A lot less side effects then Zyprexa. I feel a bit nauseous on ziprasidone but it's mild and goes away fast. TAKE WITH FOOD.
    Age: 18
    Gender: woman
    Taken for: Bipolar I disorder (manic and mixed episodes)
  • It worked very well to even out my moods. However, it greatly diminished my libido, to the point of rendering me basically asexual. I also found it took away some of my creativity (I'm an artist) and "spark."
    Age: 37
    Gender: man
    Taken for: I took it for: Mood regulation with Major Depressive Disorder and Anxiety Disorder
    Duration taken: a year or so
Weight gain or loss
  • Upsides and downsides from our pharmacists
  • It causes slightly less weight gain than similar medicines.
  • Compared to other antipsychotics, it has a lower risk of weight gain, hyperglycemia, and hyperlipidemia.
  • There was no weight gain with Geodon, unlike other medicines I have been on, I've actually been able to lose weight on it with diet and exercise. It does make you sleepy at higher doses but this side affect dwindles once your use to it.
    Taken for: Bipolar
    Duration taken: two years or more