Prescription onlyLower-cost generic availableClass: Endocrine

Glucotrol 

(glipizide)

Prescription onlyLower-cost generic availableClass: Endocrine
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Lowers blood sugar.

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Our bottom line

Glucotrol (Glipizide) is a very effective oral blood sugar-lowering medicine. It can cause low blood sugar, so make sure you know what the symptoms are and always have a source of sugar nearby.

Price and discounts
Best available price for 60 (5mg) tablets of glipizide

Upsides

  • Oral blood sugar-lowering medicine.
  • Lowers A1c levels by 1-2%. (Hemoglobin A1c measures your average blood sugar over time.)
  • Prevents the harmful effects of high sugar levels on your organs and blood vessels.
  • Might be a better choice for people with kidney problems compared to similar drugs because Glipizide isn't processed by the kidneys.
  • One of the least expensive diabetes medicines.
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Downsides

  • Higher risk of low blood sugar episodes than other kinds of oral diabetes medicines.
  • You have to check your blood sugar 2 to 5 times a week (less often once you are on a stable dose).
  • Can cause mild weight gain (2 to 3 pounds).
  • Loses effectiveness over time or as your body stops making insulin.
  • Food can cause unpredictable effects of the immediate-release version of Glipizide, so you have to take it at least 30 minutes before a meal.
How it works

Glucotrol (Glipizide) is an anti-diabetic drug. It stimulates your body to make more insulin to lower blood sugar.

What to expect when you take Glucotrol (glipizide) for Improves blood sugar levels

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Side effect rates for Glucotrol (glipizide)

  • Dizziness
  • Drowsiness
  • Headache

Risks and Warnings for Glucotrol (glipizide)

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  • Oral blood sugar lowering medicines in the sulfonylurea class, like Glucotrol (Glipizide), may increase the risk of death from heart problems when compared to controlling blood sugar with diet or diet and insulin. Talk to your doctor about the benefits, risks, and if Glucotrol (Glipizide) is right for you.

Common concerns from people taking Glucotrol (glipizide)

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Pregnancy
Alcohol
  • Avoid drinking alcohol.
Food
  • Food can cause unpredictable effects of the immediate-release version of Glipizide, so you have to take it at least 30 minutes before a meal.
  • Eat regular, balanced meals to avoid low blood sugar.
  • If not taken half an hour before a meal with enough carbs, this med causes dangerously low blood levels in the 40's. Follow food recommendations exactly.
Kidneys and liver
  • Might be a better choice for people with kidney problems compared to similar drugs because Glipizide isn't processed by the kidneys.
Weight
  • Can cause mild weight gain (2 to 3 pounds).
  • Can cause weight gain, dizziness, or stomach upset.