Prescription onlyLower-cost generic available

Diabeta

(Glyburide)

Prescription onlyLower-cost generic available
  • Pill
Back to: Full Site NavigationSkip to: side effects sectionSkip to: What to expect sectionSkip to: Risks and warnings sectionSkip to: Common concerns from users and pharmacists

Lowers blood sugar.

Skip Upsides & Downsides section. Skip to side effects section.

Our bottom line

Glyburide is a very effective oral blood sugar-lowering medicine, but has more side effects and restrictions compared to other medicines in this class (sulfonylureas).

Coupons and discounts

Upsides

  • Oral blood sugar-lowering medicine.
  • Lowers A1c levels by 1-2%. (Hemoglobin A1c measures your average blood sugar over time.)
  • Prevents the harmful effects of high sugar levels on your organs and blood vessels.
  • One of the least expensive diabetes medicines.
People say this drug is:
109 reviews

Downsides

  • Higher risk of low blood sugar episodes than other kinds of oral diabetes medicines.
  • You have to check your blood sugar 2 to 5 times a week (less often once you are on a stable dose).
  • Can cause mild weight gain (2 to 3 pounds).
  • Not preferred for people 65 years or older since it can cause prolonged low blood sugar (more than 12 hours).
  • Not a good choice for people with kidney problems because it's processed by the kidneys.
  • Loses effectiveness over time or as your body stops making insulin.

Risks and Warnings for Diabeta (Glyburide)

Skip risks section. Skip to common concerns section.
  • Oral blood sugar lowering medicines in the sulfonylurea class, like Diabeta (Glyburide), may increase the risk of death from heart problems when compared to controlling blood sugar with diet or diet and insulin. Talk to your doctor about the benefits, risks, and if Diabeta (Glyburide) is right for you.

Common concerns from people taking Diabeta (Glyburide)

Final section. Do you want to return to drug navigation?
Pregnancy
Alcohol
  • Avoid drinking alcohol.
Food
  • Eat regular, balanced meals to avoid low blood sugar.
Kidneys and liver
  • Not a good choice for people with kidney problems because it's processed by the kidneys.
Weight
  • Can cause mild weight gain (2 to 3 pounds).
  • Can cause weight gain, dizziness, or stomach upset.