Haldol Alternatives

(Haloperidol)

Alternatives

Compare Haldol (Haloperidol) to alternatives

These medications are comparable to Haldol (Haloperidol) or used for similar purposes.

Haldol
(Haloperidol)

Risperdal
(Risperidone)

Seroquel
(Quetiapine)

Abilify
(aripiprazole)

Zyprexa
(olanzapine)

chlorpromazine

Helps control your thoughts and calms agitation. Haldol (Haloperidol) is okay for treating psychosis and agitation. It's less likely to cause weight gain than other antipsychotics, but it's more likely to cause other bad side effects.Helps control your thoughts and mood. Risperdal (Risperidone) is good for treating psychosis, mania, and irritability. Among newer antipsychotic medicines, more likely to cause side effects, especially weight gain and hormone problems.Helps control your thoughts and mood. Seroquel (Quetiapine) is good for treating psychosis and mania. Fewer side effects than most antipsychotics, but might be less effective for people over age 40 with schizophrenia.Helps control your thoughts and mood. Abilify (aripiprazole) is good for treating psychosis and mania, and can help with depression. It's less likely to cause side effects than other antipsychotics.Helps control your thoughts and mood. Zyprexa (olanzapine) is good for treating psychosis, mania, and agitation, but it's more likely to cause weight gain and sleepiness than other antipsychotics.Stabilizes your mood. Thorazine (chlorpromazine) has more side effects than other medicines like it. It is most useful during psychotic episodes because it slows you down quickly.
Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
4.12Haldol
Reviews for Haldol
38%
of people (All ages) say Haldol is worth it
42%
say it works well
34%
say it's a big hassle
Have you used Haldol (Haloperidol)?
Worth itNot sureNot worth it
Reviews for Risperdal
42%
-4% worse vs. Haldol
47%
-5% worse vs. Haldol
49%
+15% better vs. Haldol
Have you used Risperdal (Risperidone)?
Worth itNot sureNot worth it
Reviews for Seroquel
56%
-18% worse vs. Haldol
50%
-8% worse vs. Haldol
27%
-7% worse vs. Haldol
250 reviews
Have you used Seroquel (Quetiapine)?
Worth itNot sureNot worth it
Reviews for Abilify
44%
-6% worse vs. Haldol
40%
+2% better vs. Haldol
34%
Same vs. Haldol
252 reviews
Have you used Abilify (aripiprazole)?
Worth itNot sureNot worth it
Reviews for Zyprexa
41%
-3% worse vs. Haldol
51%
-9% worse vs. Haldol
51%
+17% better vs. Haldol
Have you used Zyprexa (olanzapine)?
Worth itNot sureNot worth it

Not enough reviews for this treatment. Help someone out, leave a review!

Have you used Thorazine (chlorpromazine)?
Worth itNot sureNot worth it
Side effects
HaldolRisperdalSeroquelAbilifyZyprexachlorpromazine

The Haldol FDA package insert doesn’t have numbers about how common side effects are.

More about Haldol side effects »
  • Vision blurred 1%
  • Stomach discomfort 2%
  • Fatigue 1%
  • Lethargy 1%
  • Diarrhea 1%
  • Salivary hypersecretion 2%
  • Nausea 3%
  • Dystonia 4%
  • Tremor 3%
  • Dizziness 1%
More Risperdal side effects »
  • Accidental Overdose 2%
  • Acne 2%
  • Arthralgia 1%
  • Lethargy 2%
  • Pallor 2%
  • Stomach Discomfort 1%
  • Syncope 2%
  • Vision Blurred 2%
  • Constipation 2%
  • Aggression 3%
More Seroquel side effects »
  • Dizziness 4%
  • Excess drooling 6%
  • Blurred vision 8%
  • Restlessness 8%
  • Fatigue 7%
  • Nausea 7%
  • Difficulty controlling movements 17%
  • Sleepiness 20%
  • Feeling jittery 2%
  • Weight gain 1%
More Abilify side effects »
  • Feeling dizzy/faint when standing up 3%
  • Akathisia (can't sit still) 4%
  • Weight gain 5%
  • Personality disorder 4%
  • Constipation 6%
  • Dizziness 7%
  • Increased appetite 3%
  • Tremor 3%
  • Stomach problems 6%
  • Weakness 9%
More Zyprexa side effects »

The chlorpromazine FDA package insert doesn’t have numbers about how common side effects are.

More about chlorpromazine side effects »
How it works
HaldolRisperdalSeroquelAbilifyZyprexachlorpromazine
Haldol (Haloperidol) is a traditional antipsychotic. Researchers don't know exactly how it works, but it seems to change dopamine activity in your brain, which affects thoughts and mood.Risperdal (Risperidone) is an atypical antipsychotic. Researchers don't know exactly how it works. It seems to change dopamine and serotonin activity in your brain, which affects thoughts and mood.Seroquel (Quetiapine) is an atypical antipsychotic. Researchers don't know exactly how it works. It seems to change dopamine and serotonin activity in your brain, which affects thoughts and mood.Abilify (aripiprazole) is an atypical antipsychotic. It stabilizes dopamine and serotonin levels in your brain to help control your thoughts and affect mood.Zyprexa (olanzapine) is an atypical antipsychotic. Researchers don't know exactly how it works. It seems to change chemical activity (like dopamine and serotonin) in your brain, which affects thoughts and mood.Thorazine (chlorpromazine) is a derivative of phenothiazine, which regulates dopamine levels in your brain to improve your mood.
Type of medication
HaldolRisperdalSeroquelAbilifyZyprexachlorpromazine
Prescription onlyLower-cost generic availablePrescription onlyLower-cost generic availablePrescription onlyLower-cost generic availablePrescription onlyLower-cost generic availablePrescription onlyLower-cost generic availablePrescription onlyLower-cost generic available
Available as
HaldolRisperdalSeroquelAbilifyZyprexachlorpromazine
  • Pill
  • Liquid
  • Injection
  • Pill
  • Dissolving tablet
  • Liquid
  • Injection
  • Pill
  • Extended release
  • Pill
  • Dissolving tablet
  • Liquid
  • Injection
  • Pill
  • Dissolving tablet
  • Injection
  • Pill
  • Injection
Used for
HaldolRisperdalSeroquelAbilifyZyprexachlorpromazine
Risk factors for serious side effects
HaldolRisperdalSeroquelAbilifyZyprexachlorpromazine
  • Elderly patients with dementia
  • History of heart problems
  • Drug interactions
  • People with diabetes
  • People with high cholesterol
Detailed Haldol (Haloperidol) risks & warnings »
  • Elderly patients with dementia
  • History of heart problems
  • Drug interactions
  • People with diabetes
  • People with high cholesterol
Detailed Risperdal (Risperidone) risks & warnings »
  • Elderly patients with dementia
  • History of heart problems
  • Drug interactions
  • People with diabetes
  • People with high cholesterol
Detailed Seroquel (Quetiapine) risks & warnings »
  • Elderly patients with dementia
  • Age 24 years or younger
  • Use of antidepressant medications
  • People with diabetes
  • People with high cholesterol
Detailed Abilify (aripiprazole) risks & warnings »
  • Elderly patients with dementia
  • History of heart problems
  • Drug interactions
  • People with diabetes
  • People with high cholesterol
Detailed Zyprexa (olanzapine) risks & warnings »
  • People over 65 with dementia and psychosis
  • Taking antipsychotic medications
  • Asthma
  • COPD
  • Acute respiratory infections
Detailed Thorazine (chlorpromazine) risks & warnings »
Pregnancy

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

Alcohol
HaldolRisperdalSeroquelAbilifyZyprexachlorpromazine
No alcohol related info.No alcohol related info.No alcohol related info.No alcohol related info.No alcohol related info.
  • Don't combine with alcohol or narcotics because it can cause you to stop breathing.
Food
HaldolRisperdalSeroquelAbilifyZyprexachlorpromazine
  • Haldol (Haloperidol) can increase your blood sugar and cholesterol. However, Haldol (Haloperidol) is less likely to raise your blood sugar and cholesterol compared to other antipsychotic medications. Exercise and eat healthy food to lower your risk.
  • Risperdal (Risperidone) can increase your blood sugar and cholesterol. Exercise and eat healthy food to lower your risk.
  • Seroquel (Quetiapine) can increase your blood sugar and cholesterol. Seroquel (Quetiapine) is more likely to raise your blood sugar and cholesterol compared to other antipsychotic medications. Exercise and eat healthy food to lower your risk.
No food related info.No food related info.No food related info.
Sleep
HaldolRisperdalSeroquelAbilifyZyprexachlorpromazine
  • It can cause dizziness, drowsiness, and can lower your blood pressure.
  • Can cause dizziness and drowsiness.
  • Can cause dizziness, drowsiness, and low blood pressure.
No sleep related info.
  • Can cause dizziness and drowsiness.
  • Might make you more sleepy than some antipsychotics.
  • Can make you very sleepy so don't drive or do anything that requires concentration until you know how it affects you.
Weight
HaldolRisperdalSeroquelAbilifyZyprexachlorpromazine
  • Haldol (Haloperidol) can cause you to gain weight. However, Haldol (Haloperidol) is less likely to cause weight gain compared to other antipsychotic medications. Exercise and eat healthy food to lower your risk.
  • Less likely to cause weight gain and problems with cholesterol and blood sugar than most other antipsychotics.
  • Risperdal (Risperidone) can cause you to gain weight. Exercise and eat healthy food to lower your risk.
  • May cause weight gain and worsen cholesterol or blood sugar.
  • Moderate risk of weight gain and problems with cholesterol or blood sugar compared to other antipsychotics.
  • Seroquel (Quetiapine) can cause you to gain weight. Seroquel (Quetiapine) is moderately likely to cause weight gain compared to other antipsychotic medications. Exercise and eat healthy food to lower your risk.
  • May cause weight gain and worsen cholesterol or blood sugar.
  • Sometimes causes weight gain, sleepiness, and low blood pressure.
  • Abilify (aripiprazole) can make you gain weight, which can also increase your blood sugar and cholesterol. If you're at risk for diabetes, high blood pressure or high cholestetrol, talk to your doctor how to lower your risk.
  • Zyprexa (olanzapine) is more likely to raise your blood sugar and cholesterol compared to other antipsychotic medications. Zyprexa (olanzapine) can also cause you to gain weight. Exercise and eat healthy food to lower your risk.
  • May cause weight gain and increased cholesterol or blood sugar.
  • More likely to cause weight gain and increase cholesterol or blood sugar compared to other antipsychotics.
No weight related info.
Upsides and benefits
HaldolRisperdalSeroquelAbilifyZyprexachlorpromazine
  • Effective at relieving psychotic symptoms and agitation.
  • Works just as well as other antipsychotic medicines.
  • Less likely to cause weight gain and problems with cholesterol and blood sugar than most other antipsychotics.
  • Effective at relieving psychotic symptoms, manic episodes, irritability, and aggressive behavior.
  • Lowers relapse rates in people with schizophrenia and people with irritability associated with autism.
  • Antipsychotic medicines are all about equally effective.
  • Less likely to cause heart problems than some antipsychotics.
  • Effective at relieving psychotic symptoms and manic episodes.
  • Antipsychotic medicines are all about equally effective.
  • Fewer side effects than most antipsychotic medicines.
  • Less likely to cause heart problems compared to some antipsychotics.
  • Compared to other antipsychotics, the least likely to cause Extrapyramidal Symptoms (EPS): Movement disorders that include stiffness, tremor, restlessness, and slow, repetitive, or involuntary movements.
  • Effective at relieving psychotic symptoms and manic episodes.
  • More energizing than other antipsychotics.
  • Fewer side effects than other antipsychotics.
  • Studies show that it can also be helpful for depression, especially in women, if your symptoms don't go away with an antidepressant alone.
  • Available as a generic, which is cheaper.
  • Effective at relieving psychotic symptoms, manic episodes, and agitation in people with schizophrenia and bipolar disorder.
  • Less likely to cause heart problems than other antipsychotics.
  • Less likely to cause movement problems compared to older antipsychotics.
  • Acts fast to slow you down during a psychotic episode.
  • Can also be used for nausea or migraines.
  • Safe for use in children as young as 6 months.
  • Comes in a sugar-coated pill for easy administration.
Downsides and risks
HaldolRisperdalSeroquelAbilifyZyprexachlorpromazine
  • It's an older medicine and has a lot more side effects than newer antipsychotics.
  • Compared to other antipsychotics, it causes more hormone problems that can cause nipples to leak fluid, and sudden, dangerous abnormal heart rhythms.
  • Has a higher risk of extrapyramidal symptoms (EPS): movement disorders that include stiffness, tremor, restlessness, and slow, repetitive, or involuntary movements. One of these symptoms (called tardive dyskinesia) is permanent and more likely if you take this medicine for many years.
  • You might need routine blood tests to check how the medicine is affecting your body.
  • All antipsychotics have side effects that make them difficult to take. You might need to try a few different medicines until you find one that works best for you.
  • Mild to moderate risk of Extrapyramidal Symptoms (EPS): Movement disorders that include stiffness, tremor, restlessness, and slow, repetitive, or involuntary movements.
  • Moderate risk of weight gain and problems with cholesterol or blood sugar compared to other antipsychotics.
  • Compared to other antipsychotics, higher risk of hormone problems that cause nipples to leak and male breasts to grow abnormally large.
  • You might need routine blood tests to check how the medicine is affecting your body.
  • All antipsychotics come with side effects that make them difficult to take. You might need to try a few different medicines until you find one that works for you and that you can tolerate.
  • In studies, less effective for people over age 40 for schizophrenia.
  • Sometimes causes weight gain, sleepiness, and low blood pressure.
  • You might need routine blood tests to check how the medicine is affecting your body.
  • All antipsychotics come with side effects that make them difficult to take. You might need to try a few different medicines until you find one that works for you and that you can tolerate.
  • Mild risk of extrapyramidal symptoms (EPS), a movement disorder that includes stiffness, tremor, restlessness, and slow, repetitive, or involuntary movements.
  • You might need routine blood tests to check how the medicine is affecting your body.
  • All antipsychotics come with side effects that make them difficult to take. You might need to try a few different medicines until you find the one that works for you and that you can tolerate.
  • More likely to cause weight gain and increase cholesterol or blood sugar compared to other antipsychotics.
  • Might make you more sleepy than some antipsychotics.
  • Mild risk of Extrapyramidal Symptoms (EPS): Movement disorders that include stiffness, tremor, restlessness, and slow, repetitive movements you can't control.
  • You may need routine blood tests to check how the medicine is affecting your body..
  • Has more side effects than other medicines like it.
  • Can affect how your other medicines work.
  • Makes you more sensitive to the sun.
  • Can make you dizzy or lightheaded, especially when injected.
  • Cannot be stopped right away.
Tips from our pharmacists for people taking the medication
HaldolRisperdalSeroquelAbilifyZyprexachlorpromazine
  • It'll take 4 to 6 weeks to see the medication's full effects on your thoughts.
  • It can cause dizziness, drowsiness, and can lower your blood pressure.
  • For the first week, avoid activities like driving that require you to be alert.
  • Immediately tell your doctor if you can't control your muscle movements or if you have a fever or excess sweating.
  • Don't use in elderly people who have dementia.
  • The oral liquid concentrate can be mixed with water or juice before taking it.
  • Takes 4 to 6 weeks to see full effects on thoughts and mood.
  • Can cause dizziness and drowsiness.
  • For the first week, avoid activities that require you to be alert.
  • May cause weight gain and worsen cholesterol or blood sugar.
  • Report any unusual thoughts, inability to control muscle movements, or fever and excess sweating to your doctor.
  • Elderly people with dementia shouldn't take it.
  • Takes 4 to 6 weeks to see full effects on thoughts and mood.
  • Can cause dizziness, drowsiness, and low blood pressure.
  • For the first week, avoid activities that require you to be alert.
  • May cause weight gain and worsen cholesterol or blood sugar.
  • Report any unusual thoughts, inability to control muscle movements, or fever and excess sweating to your doctor.
  • Elderly people with dementia shouldn't take it.
  • Takes 4 to 6 weeks to see full effects on thoughts and mood.
  • Makes you energized. Take in the morning to avoid difficulty sleeping.
  • For the first week, avoid activities that require you to be alert.
  • May increase cholesterol or blood sugar.
  • Report any unusual thoughts, inability to control muscle movements, or fever and excess sweating to your doctor.
  • Available in pills that you take daily, and as a monthly injection.
  • Takes at least 4 to 6 weeks to see full effects on thoughts and mood.
  • Can cause dizziness and drowsiness.
  • For the first week, avoid activities that require you to be alert.
  • May cause weight gain and increased cholesterol or blood sugar.
  • Report any unusual thoughts, inability to control muscle movements, or fever and excess sweating to your doctor.
  • Elderly people with dementia shouldn't take Zyprexa (olanzapine).
  • Can make you very sleepy so don't drive or do anything that requires concentration until you know how it affects you.
  • Can cause involuntary muscle movements just like other medicines for your mood.
  • Can dry you out and make you more sensitive to the sun.
  • Don't combine with alcohol or narcotics because it can cause you to stop breathing.
  • Cannot be stopped suddenly.
Learn more
More about HaldolSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Haldol (Haloperidol)?
Worth itNot sureNot worth it
More about RisperdalSide effectsReviews & ratingsFDA package insert
Have you used Risperdal (Risperidone)?
Worth itNot sureNot worth it
More about SeroquelSide effectsReviews & ratingsFDA package insert
Have you used Seroquel (Quetiapine)?
Worth itNot sureNot worth it
More about AbilifySide effectsReviews & ratingsFDA package insert
Have you used Abilify (aripiprazole)?
Worth itNot sureNot worth it
More about ZyprexaSide effectsReviews & ratingsFDA package insert
Have you used Zyprexa (olanzapine)?
Worth itNot sureNot worth it
More about chlorpromazineSide effectsFDA package insert
Have you used Thorazine (chlorpromazine)?
Worth itNot sureNot worth it