Prescription onlyLower-cost generic available

Hectorol Alternatives

(Doxercalciferol)

  • Pill
  • Intravenous (IV) solution
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Compare Hectorol (Doxercalciferol) to alternatives

These medications are comparable to Hectorol (Doxercalciferol) or used for similar purposes.

Hectorol
(Doxercalciferol)

Rocaltrol
(Calcitriol)

Raises Vitamin D levels. Hectorol (Doxercalciferol) works well for people with low vitamin D in kidney disease, but you'll need regular blood tests and you have to avoid certain antacids.Raises Vitamin D levels. Rocaltrol (Calcitriol) is the strongest form of vitamin D available, but it's prescription-only and more expensive than over-the-counter alternatives, and you have to get regular blood tests.
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Reviews & ratings
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4.1891891891891895Hectorol
Reviews for Hectorol (Doxercalciferol)
43%
of people say Hectorol (Doxercalciferol) is worth it
30%
say it works well
19%
say it's a big hassle

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Side effects
HectorolRocaltrol

We haven’t found good data for Hectorol side effects.

FDA side effect reports for Hectorol »

We haven’t found good data for Rocaltrol side effects.

FDA side effect reports for Rocaltrol »
How it works
HectorolRocaltrol
Hectorol (Doxercalciferol) is a synthetic form of Vitamin D2. It raises Vitamin D levels in your blood, which calms down overactive parathyroid glands. (Too much parathyroid hormone weakens your bones.) This issue is common in people with kidney disease because unhealthy kidneys can't convert Vitamin D to its active form.Rocaltrol (Calcitriol) is the active form of Vitamin D. It raises Vitamin D levels in your blood. This in turn raises calcium levels in your blood by helping you absorb more calcium from food in your intestine.
Type of medication
HectorolRocaltrol
Vitamin DPrescription only
Vitamin DPrescription only
Available as
HectorolRocaltrol
  • Pill
  • Intravenous (IV) solution
  • Pill
  • Liquid
  • Injection
Used for (click to learn more)
HectorolRocaltrol
Risk factors for serious side effects
HectorolRocaltrol
    Detailed Hectorol (Doxercalciferol) risks & warnings »
    Coming soon.
    Pregnancy category
    HectorolRocaltrol
    BFDA pregnancy category (Probably safe)

    Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

    See the FDA package insert
    CFDA pregnancy category (Weigh risks vs. benefits)

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    See the FDA package insert
    Alcohol
    No specific alcohol-related info.No specific alcohol-related info.
    Food
    No specific food-related info.No specific food-related info.
    Kidneys and liver
    • Effective for treating overactive parathyroid glands due to kidney disease.
    • People on Hectorol (Doxercalciferol) who take more than the recommended dose can have high calcium in the blood, which can be dangerous in the kidneys. If you notice a metallic taste in your mouth, muscle or joint pain or a bad headache, talk to your doctor. Keep the amount of calcium you eat the same from day to day.
    • The strongest form of vitamin D that's available to help keep your calcium levels in line in case your parathyroid or kidneys aren't working like they should.
    Sex
    No specific sex-related info.No specific sex-related info.
    Sleep
    No specific sleep-related info.No specific sleep-related info.
    Weight
    No specific weight-related info.No specific weight-related info.
    Upsides and benefits
    HectorolRocaltrol
    • Effective for treating overactive parathyroid glands due to kidney disease.
    • Available as a generic.
    • Available as either an oral capsule or an IV solution.
    • It's made from the plant-based version of vitamin D, so it's useful for vegetarians.
    • The strongest form of vitamin D that's available to help keep your calcium levels in line in case your parathyroid or kidneys aren't working like they should.
    • Available in generic.
    • Available in both intravenous infusion and oral capsule form.
    Downsides and risks
    HectorolRocaltrol
    • Can interact with antacids that contain magnesium.
    • Your doctor will want to take blood tests to make sure that your body is responding to the medication.
    • Your doctor may prescribe other medications to make sure other chemicals (phosphate and calcium) in your body remain in balance.
    • Can interact with antacids containing magnesium.
    • Your doctor will want to take blood tests to make sure that your body is responding to the medication.
    • Your doctor may prescribe other medications to make sure other chemicals (phosphate and calcium) in your body remain in balance.
    Tips from our pharmacists for people taking the medication
    HectorolRocaltrol
    • Don't take other forms of vitamin D unless told to by your doctor.
    • Avoid antacids containing magnesium.
    • Can be given as a capsule or as a shot.
    • Can cause swelling in the legs, weakness, nausea and vomiting.
    • If you're using the ointment, avoid extended exposure to sunlight or tanning beds.
    • Make sure to take at least 600 to 1200 mg of calcium per day.
    • Drink plenty of fluids while you're on this medication.
    • Call your doctor if you notice a metallic taste in your mouth, muscle or joint pain, headache or sleepiness.
    • Keep your diet and calcium intake consistent every day.
    Learn more
    More about HectorolSide effectsReviews & ratingsAlternativesFDA package insert
    More about RocaltrolSide effectsReviews & ratingsFDA package insert