Prescription onlyClass: Autoimmune



Prescription onlyClass: Autoimmune
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Calms down the immune system.

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Our bottom line

Humira (adalimumab) is good for treating many autoimmune conditions, but it can also cause serious side effects.

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Price and discounts
Best available price for 1 (2 pens of 40mg/0.8ml) carton of adalimumab


  • Humira (adalimumab) is effective in reducing symptoms in all of its approved indications.
  • You can give yourself Humira (adalimumab) on your own at home rather than visiting a clinic or hospital.
  • Humira (adalimumab) treats many different autoimmune conditions.
  • Available in a single-use pen (Humira Pen) that may be more convenient and easier for some people to use.
People say this drug is:
182 reviews


  • Not first-choice treatment for rheumatoid arthritis.
  • Humira (adalimumab) is an injection and not an oral medication.
  • Humira (adalimumab) is expensive because there's no generic available yet.
  • Humira (adalimumab) lowers your ability to fight infection and in some cases can cause serious life-threatening illness. The risk is greater if you take other drugs that lower your immune system, have an active infection, diabetes, or had tuberculosis (TB) in the past.
  • You'll need to properly dispose of the needle, syringes, or Pen in a sharps container.
  • Humira (adalimumab) needs to be refrigerated until you use it, so if you're traveling, you'll need to carry it in a cooler with an ice pack.
How it works

Humira (adalimumab) is a TNF blocker which stops inflammation.

What to expect when you take Humira (adalimumab) for Autoimmune diseases

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Side effect rates for Humira (adalimumab)

1395 From clinical trials of Humira / Rheumatoid arthritis (40 mg every other week)
  • Upper airway infection
  • Rash
  • Headache
  • Sinus infection
  • Nausea
  • Injection site reactions
  • Urinary tract infection
  • Flu syndrome
  • Stomach pain
  • High cholesterol

Risks and Warnings for Humira (adalimumab)

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    • Higher risk if:
    • Taking other immunosuppressant medications such as Kineret or Orencia
    • Age 65 or older
    • Active, chronic, or recurrent infection
    • Comorbidities

    Humira (adalimumab) can increase your risk of serious or life-threatening infections. In some cases, existing inactive infections can be reactivated such as tuberculosis (TB) or hepatitis B virus (HBV). You may need to take medicine for TB before you can begin taking Humira (adalimumab). If you develop symptoms of cough, fever, chills, muscle aches, fatigue, dark urine, yellowing of skin/eyes, loss of appetite, vomiting, change in stool color, stomach discomfort, or skin rash, tell your doctor right away.

    This is a black box warning. The FDA requires this warning when there is a significant risk of serious or life-threatening effects that anyone taking the drug should consider.

Means that some groups have a high risk of experiencing this side effect

Common concerns from people taking Humira (adalimumab)

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  • the cost of the medication is really the main issue
  • Don't drink alcohol the day before for less pain. Always had bruising and muscle pain for day after injection. Along with headache.
  • Travelling can be huge pain with this refridgeerator medication. There are 30 hour chill containers out there. One piece of advice that really help me is if you can find ice. Do to the nearest fast food place and bring a ziploc bag
  • No pain from using pen injection. Had to check it had actually pierced the skin. However, suffering from joint, neck & back pain, blurred vision and occasional head rush. On a positive Chrohns flare has ceased. So a mixed opinion.
  • Humira worked great. It took away the pain and swelling. After 2 doses I felt relief from RA.