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Calms down your immune system.

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Prescription onlyNo lower cost generic available

Our pharmacists’ bottom line

Humira (Adalimumab) is very effective at calming down your immune system, but it's expensive, you have to take into account the hassle of injections and traveling with the medication.

Worth it?Is it worth it?
Works well?Does it work?
Hassle?Is it a hassle?
  • Treats certain types of arthritis and gastrointestinal conditions caused by an overactive immune system.
  • Most people feel it's worth the hassle.
  • Once you've learned the correct way to use Humira, you can inject the medicine yourself without going to your doctor's office.
  • It's available in a single-use pen (Humira Pen) that may be more convenient and easier for some people to use.
  • It's an alternative for people with Crohn's disease who stopped getting better on other TNF-blockers or had side effects that made them switch.
  • It's an injection.
  • It's expensive because there's no generic available yet.
  • Humira lowers your ability to fight infection and can cause serious life-threatening illness. The risk is greater if you take other drugs that lower your immune system, have an active infection, diabetes, or had tuberculosis (TB) in the past.
  • You're first dose of Humira will need to be given at your doctor's office. If you decide not to self-inject and don't have someone to do it for you, you'll need to continue to see your doctor for each dose.
  • You'll need to properly dispose of the needle, syringes, or Pen in a special (FDA-approved) sharps container.
  • Because it needs to be refrigerated until you use it, if you're traveling, you'll need to carry it in a cooler with an ice pack.

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Side effects for Humira (Adalimumab)

From clinical trials of Humira / Any condition ( 11536)

  • Injection site reactionsInjection site reactions20% for Humira vs.14% for placebo
  • Serious infectionsSerious infections5% for Humira vs.3% for placebo
  • Alt increased (>3x)Alt increased (>3x)4% for Humira vs.2% for placebo

What to expect when you start Humira (Adalimumab)

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Tips from our pharmacists
  • Humira (Adalimumab) is a medication that's injected under the skin (subcutaneous). Your doctor can give you your first dose, then let you self-inject it once so you learn how to do it correctly.
  • Humira (Adalimumab) lowers the your immune system's ability to fight infections, so it's important to let your doctor know if you come down with a fever, cough, or notice flu-like symptoms.
  • You'll need to have a TB test before you start using Humira (Adalimumab).
  • Tell your doctor if you have an allergy to latex since the syringe needle cover has latex in it.
  • Don't inject Humira (Adalimumab) into skin that's red, bruised, or irritated. Rotate your injection areas to avoid skin reactions.
  • As with all injection medicines, store away from children and throw used syringes away in a protective container, and not in the trash.

Risks and Warnings for Humira (Adalimumab)

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  • Humira (Adalimumab) has been reported to cause hypersensitivity reactions (severe rash, trouble breathing) and angioedema (life-threatening condition with swelling with or without hives). If you notice these symptoms after your dose or days later, call your doctor and get medical care right away.

Means that some groups have a high risk of experiencing this side effect

Tips from pharmacists and people taking Humira (Adalimumab)

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The FDA category for this medication is B. It is advised that you: Probably safe
  • Don't drink alcohol the day before for less pain. Always had bruising and muscle pain for day after injection. Along with headache.
    Age: 22
    Gender: man
    Taken for: Crohn's disease (moderate to severe)
  • Travelling can be huge pain with this refridgeerator medication. There are 30 hour chill containers out there. One piece of advice that really help me is if you can find ice. Do to the nearest fast food place and bring a ziploc bag
    Age: 31
    Gender: man
    Taken for: Crohn's disease (moderate to severe)
    Duration taken: two years or more
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  • Risks from our pharmacists
  • Humira (Adalimumab) can increase your risk of serious or life-threatening bacterial, fungal and viral infections. In some cases infections can be reactivated from an inactive virus in your body like tuberculosis (TB) or hepatitis B virus (HBV). You may need to take medicine for TB before you can begin taking Humira (Adalimumab). If you develop symptoms of cough, fever, chills, muscle aches, feel very tired, or you notice dark urine, yellowing of skin/eyes, appetite/weight loss, vomiting, change in stool color, stomach discomfort, and skin rash, tell your doctor and get medical care right away.