Prescription onlyNo lower cost generic available



Prescription onlyNo lower cost generic available
Back to: Full Site NavigationSkip to: side effects sectionSkip to: What to expect sectionSkip to: Risks and warnings sectionSkip to: Common concerns from users and pharmacists

Calms down your immune system.

Skip Upsides & Downsides section. Skip to side effects section.

Our bottom line

Humira (Adalimumab) is very effective at calming down your immune system, but it's expensive, you have to take into account the hassle of injections and traveling with the medication.

Coupons and discounts


  • Treats certain types of arthritis and gastrointestinal conditions caused by an overactive immune system.
  • Most people feel it's worth the hassle.
  • Once you've learned the correct way to use Humira, you can inject the medicine yourself without going to your doctor's office.
  • It's available in a single-use pen (Humira Pen) that may be more convenient and easier for some people to use.
  • It's an alternative for people with Crohn's disease who stopped getting better on other TNF-blockers or had side effects that made them switch.
People say this drug is:
164 reviews


  • It's an injection.
  • It's expensive because there's no generic available yet.
  • Humira lowers your ability to fight infection and can cause serious life-threatening illness. The risk is greater if you take other drugs that lower your immune system, have an active infection, diabetes, or had tuberculosis (TB) in the past.
  • You're first dose of Humira will need to be given at your doctor's office. If you decide not to self-inject and don't have someone to do it for you, you'll need to continue to see your doctor for each dose.
  • You'll need to properly dispose of the needle, syringes, or Pen in a special (FDA-approved) sharps container.
  • Because it needs to be refrigerated until you use it, if you're traveling, you'll need to carry it in a cooler with an ice pack.

What to expect when you take Humira (Adalimumab) for Rheumatoid arthritis

Skip what to expect section. Skip to Risks & Warnings section.
Skip side effects section. Skip to What to Expect and Pharmacists Tips section.

Side effect rates for Humira (Adalimumab)

From clinical trials of Humira / Any condition
  • Injection site reactions
  • Serious infections
  • Alt increased (>3x)

Risks and Warnings for Humira (Adalimumab)

Skip risks section. Skip to common concerns section.
  • Humira (Adalimumab) has been reported to cause hypersensitivity reactions (severe rash, trouble breathing) and angioedema (life-threatening condition with swelling with or without hives). If you notice these symptoms after your dose or days later, call your doctor and get medical care right away.

Means that some groups have a high risk of experiencing this side effect

Common concerns from people taking Humira (Adalimumab)

Final section. Do you want to return to drug navigation?
  • Don't drink alcohol the day before for less pain. Always had bruising and muscle pain for day after injection. Along with headache.
  • Travelling can be huge pain with this refridgeerator medication. There are 30 hour chill containers out there. One piece of advice that really help me is if you can find ice. Do to the nearest fast food place and bring a ziploc bag
  • Find the shot painful, very painful. Does help to let it get to room temperature, but the pain is still more than I expect., stings like hell!
  • This drug gave me my life back. I had gotten to the wheelchair stage with back pain and was retired early on health grounds. Once the Humira kicked in I didn't even need a stick to walk anymore, so retirement is OK! My tip is that, if you were put on other drugs to treat back pain before going on Humira, you might want to consider coming off them once the Humira works. Oh, and I'm terrified of needles, but the new formulation feels completely painless (1hr warm up)