Prescription onlyLower-cost generic availableClass: Cardiovascular


(hydrochlorothiazide )

Prescription onlyLower-cost generic availableClass: Cardiovascular
Back to: Full Site NavigationSkip to: side effects sectionSkip to: What to expect sectionSkip to: Risks and warnings sectionSkip to: Common concerns from users and pharmacists

Removes water from the body, which lowers blood pressure.

Skip Upsides & Downsides section. Skip to side effects section.

Our bottom line

Microzide (hydrochlorothiazide (HCTZ)) is a well-tolerated water pill that's often the first-choice treatment for mild high blood pressure.

No pricing data for this drug at this filter setting. Try searching onGoodRx


  • Does a good job getting rid of extra fluids in your body by making you urinate more.
  • A first-choice blood pressure treatment. Works especially well for people of African descent.
  • Lowers the risk of heart attack and stroke.
  • Good option if you have high blood pressure and heart failure.
  • Most people have very few side effects from Microzide (hydrochlorothiazide (HCTZ)).
  • Can be good for patients with osteoporosis since it raises the body's level of calcium.
People say this drug is:
139 reviews


  • Makes you urinate more often.
  • Microzide (hydrochlorothiazide (HCTZ)) doesn't work well in people with severe kidney problems.
  • It can increase the risk of gout attacks in people with poor kidney function or a history of gout.
  • People with a sulfa allergy may be allergic to Microzide (hydrochlorothiazide (HCTZ)).
How it works

Microzide (hydrochlorothiazide (HCTZ)) is a thiazide diuretic (water pill) that makes you urinate more. It works in the kidneys to remove extra water and certain electrolytes, while lowering blood pressure and reducing swelling.

What to expect when you take Microzide (hydrochlorothiazide ) for High blood pressure

Skip what to expect section. Skip to Risks & Warnings section.
Skip side effects section. Skip to What to Expect and Pharmacists Tips section.

Side effect rates for Microzide (hydrochlorothiazide )

Risks and Warnings for Microzide (hydrochlorothiazide )

Skip risks section. Skip to common concerns section.
    • Higher risk if:
    • Current electrolyte imbalance
    • Lower kidney function
    • Dehydration

    Taking too much Microzide (hydrochlorothiazide (HCTZ)) can cause excessive urine production, which leads to dehydration and low levels of sodium, potassium, or magnesium. This can affect your heart and other muscles. Any current fluid or electrolyte imbalances should be corrected before using Microzide (hydrochlorothiazide (HCTZ)). Make sure to stay hydrated while you're taking Microzide (hydrochlorothiazide (HCTZ)).

Common concerns from people taking Microzide (hydrochlorothiazide )

Final section. Do you want to return to drug navigation?
Kidneys and liver
  • Requires routine blood tests to check kidney function.