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Microzide Alternatives

(Hydrochlorothiazide )

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Compare Microzide (Hydrochlorothiazide (Hctz)) to alternatives

These medications are comparable to Microzide (Hydrochlorothiazide (Hctz)) or used for similar purposes.

Microzide
(Hydrochlorothiazide )

Lasix
(Furosemide)

Zestril
(Lisinopril)

Aldactone
(Spironolactone)

Edecrin
(Ethacrynic Acid)

Lanoxin
(Digoxin)

Lowers blood pressure. Removes extra water from your body. Microzide (Hydrochlorothiazide (Hctz)) is a well-tolerated water pill that's often the first-choice treatment for mild high blood pressure.Lowers blood pressure. Removes extra water from your body. Lasix (Furosemide) is a very effective water pill and it'll certainly make you go to the bathroom more often.Lowers blood pressure. Zestril (Lisinopril) is a good blood pressure-lowering medicine that protects kidney function.Removes extra water from your body. Aldactone (Spironolactone) is helpful when added to another diuretic to get rid of excess fluid in your body. Doesn't work well on its own.Coming soon.Improves heart pumping. Digoxin is a good backup for treating heart failure symptoms, but it doesn't, by itself, lower your risk of death.
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Reviews & ratings
Button Group. All currently active
Button Group. All currently active
4.467153284671533Hydrochlorothiazide
Reviews for Microzide (Hydrochlorothiazide (Hctz))
47%
of people say Microzide (Hydrochlorothiazide (Hctz)) is worth it
31%
say it works well
15%
say it's a big hassle
Reviews for Lasix (Furosemide)
66%
+19% vs. Microzide (Hydrochlorothiazide (Hctz))
47%
+16% vs. Microzide (Hydrochlorothiazide (Hctz))
16%
1% vs. Microzide (Hydrochlorothiazide (Hctz))
Reviews for Zestril (Lisinopril)
61%
+14% vs. Microzide (Hydrochlorothiazide (Hctz))
51%
+20% vs. Microzide (Hydrochlorothiazide (Hctz))
13%
+2% vs. Microzide (Hydrochlorothiazide (Hctz))

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Not enough reviews for this drug. Help someone out, leave a review!

Reviews for Lanoxin (Digoxin)
64%
+17% vs. Microzide (Hydrochlorothiazide (Hctz))
43%
+12% vs. Microzide (Hydrochlorothiazide (Hctz))
31%
16% vs. Microzide (Hydrochlorothiazide (Hctz))
Side effects
HydrochlorothiazideLasixLisinoprilAldactoneEdecrinDigoxin

The Hydrochlorothiazide FDA package insert doesn’t have numbers about how common side effects are.

More about Hydrochlorothiazide side effects »

The Lasix FDA package insert doesn’t have numbers about how common side effects are.

More about Lasix side effects »
  • Dizziness 7%
  • Headache 4%
  • Cough 3%
  • Diarrhea 2%
  • Chest pain 2%
  • Fatigue 2%
  • Upper respiratory infection 1%
More Lisinopril side effects »

We haven’t found good data for Aldactone side effects.

FDA side effect reports for Aldactone »

We haven’t found good data for Edecrin side effects.

FDA side effect reports for Edecrin »
  • Dizziness 1%
  • Side effects requiring hospitalization 1%
  • Nausea 1%
  • Death 1%
More Digoxin side effects »
How it works
HydrochlorothiazideLasixLisinoprilAldactoneEdecrinDigoxin
Microzide (Hydrochlorothiazide (Hctz)) is a thiazide diuretic (water pill). It works in the kidneys to make you urinate more, which removes extra water and certain electrolytes. This lowers blood pressure and swelling.Lasix (Furosemide) is a loop diuretic (water pill). It works in the kidneys to make you urinate more, which removes extra water and certain electrolytes. This lowers blood pressure and swelling.Zestril (Lisinopril) is an angiotensin converting enzyme (ACE) inhibitor. It blocks a chemical that tightens blood vessels. This makes blood vessels relax, which lowers blood pressure and allows more blood and oxygen to get to your heart and other organs.Aldactone (Spironolactone) is a potassium-sparing diuretic that blocks aldosterone (a hormone) and helps the kidney get rid of excess fluids in your body.Coming soon.Digoxin helps your heart work more efficiently. It makes your heart pump slower and stronger, which helps it get more blood and oxygen out to your body and organs.
Type of medication
HydrochlorothiazideLasixLisinoprilAldactoneEdecrinDigoxin
Antihypertensive
Diuretic
Prescription only
Antihypertensive
Diuretic
Prescription only
Antihypertensive
ACE inhibitor
Prescription only
Antihypertensive
Diuretic
Prescription only
Coming soon.
Anti-arrhythmic
Inotrope
Prescription only
Available as
HydrochlorothiazideLasixLisinoprilAldactoneEdecrinDigoxin
  • Pill
  • Pill
  • Liquid
  • Pill
  • Pill
  • Pill
  • Pill
  • Liquid
Used for (click to learn more)
HydrochlorothiazideLasixLisinoprilAldactoneEdecrinDigoxin
  • Edema
Risk factors for serious side effects
HydrochlorothiazideLasixLisinoprilAldactoneEdecrinDigoxin
  • Current electrolyte imbalance
  • History of sulfa allergies
  • History of gout
  • Current kidney problems
    Detailed Microzide (Hydrochlorothiazide (Hctz)) risks & warnings »
    Coming soon.Coming soon.Coming soon.Coming soon.Coming soon.
    Pregnancy category
    HydrochlorothiazideLasixLisinoprilAldactoneEdecrinDigoxin
    BFDA pregnancy category (Probably safe)

    Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

    See the FDA package insert
    CFDA pregnancy category (Weigh risks vs. benefits)

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    See the FDA package insert
    DFDA pregnancy category (Weigh risks vs. benefits)

    Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    See the FDA package insert
    CFDA pregnancy category (Weigh risks vs. benefits)

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    See the FDA package insert
    BFDA pregnancy category (Probably safe)

    Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

    See the FDA package insert
    CFDA pregnancy category (Weigh risks vs. benefits)

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    See the FDA package insert
    Alcohol
    No specific alcohol-related info.No specific alcohol-related info.No specific alcohol-related info.No specific alcohol-related info.No specific alcohol-related info.No specific alcohol-related info.
    Food
    No specific food-related info.No specific food-related info.No specific food-related info.No specific food-related info.No specific food-related info.No specific food-related info.
    Kidneys and liver
    • Doesn't work well in people with severe kidney problems.
    • Requires routine blood tests to check kidney function.
    • Okay to take if you have kidney problems.
    • Requires routine blood tests to check kidney function.
    • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
    • Requires routine blood tests to check kidney function.
    • Needs to have blood tests done to monitor electrolyte levels and kidney function.
    No specific kidneys and liver-related info.No specific kidneys and liver-related info.
    Sex
    No specific sex-related info.No specific sex-related info.No specific sex-related info.
    • You can have breast pain/swelling, irregular periods (women), or trouble with sexual performance.
    No specific sex-related info.No specific sex-related info.
    Sleep
    No specific sleep-related info.No specific sleep-related info.No specific sleep-related info.No specific sleep-related info.No specific sleep-related info.No specific sleep-related info.
    Weight
    No specific weight-related info.No specific weight-related info.No specific weight-related info.No specific weight-related info.No specific weight-related info.No specific weight-related info.
    Upsides and benefits
    HydrochlorothiazideLasixLisinoprilAldactoneEdecrinDigoxin
    • Works well to get rid of extra fluids in your body through urination.
    • A first-choice blood pressure treatment for many people. Works especially well for African Americans.
    • Good option if you have both high blood pressure and heart failure.
    • Raises calcium levels in the body, so it can be good for people with osteoporosis to slow down bone loss and even help with new bone formation.
    • Most people have very few side effects.
    • Lowers the risk of heart attack and stroke.
    • A strong diuretic (water pill) that works well to get rid of extra fluids in your body through urination.
    • Lowers your blood pressure and your risk of heart attack and stroke.
    • Works better than thiazide diuretics (like Hydrochlorothiazide) at removing harmful levels of certain electrolytes, such as potassium.
    • Okay to take if you have kidney problems.
    • A first-choice blood pressure treatment for many people.
    • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
    • Recommended for anyone with heart failure since it lowers the risk of death and further damage to your heart.
    • Lowers the risk of heart attack and stroke.
    • Has a low risk of causing muscle problems due to low potassium levels in your blood.
    • More useful when taken with another diuretic that'll also help your body get rid of extra fluids.
    • Can lower blood pressure.
    • Reduces the risk of death in people with heart failure.
    Coming soon.
    • Used for some abnormal heart rhythms, and for heart failure that can't be controlled by other medications.
    • Relieves shortness of breath, and makes it easier to be active without having symptoms.
    • In studies, Digoxin lowered the risk of having to be admitted to the hospital for worsening heart failure.
    Downsides and risks
    HydrochlorothiazideLasixLisinoprilAldactoneEdecrinDigoxin
    • Makes you urinate more often.
    • Doesn't work well in people with severe kidney problems.
    • Makes you urinate very frequently.
    • Can cause low levels of important electrolytes, such as potassium.
    • Up to 1 in 10 people can get a dry cough with this medicine. It ranges from a mild tickle in the throat to a persistent hacking cough.
    • Requires a yearly blood test to see how the medicine is affecting your body.
    • Not safe to use if you're pregnant.
    • Not very good at getting rid of excess fluids on its own. Should be used with another drug to help get rid of excess fluids.
    • Has many possible side effects, especially when higher doses are used.
    • Can increase the risk of tumor growth.
    • Needs to have blood tests done to monitor electrolyte levels and kidney function.
    Coming soon.
    • For heart failure, relieves symptoms, but does not lower the risk of death. That's why it's usually used together with other heart failure medicines that do lower the risk of death.
    • Requires blood tests, especially during the first few weeks of treatment.
    Tips from our pharmacists for people taking the medication
    HydrochlorothiazideLasixLisinoprilAldactoneEdecrinDigoxin
    • Starts working in about 2 hours.
    • Makes you urinate more often, so avoid taking it at bedtime.
    • Can cause dizziness in the first few days.
    • Check your blood pressure 1 week after starting this medicine, and tell your doctor if it hasn't improved.
    • Tell your doctor about any dizziness, fatigue, or muscle weakness that doesn't go away.
    • Requires routine blood tests to check kidney function.
    • Starts working in 30 minutes.
    • Makes you urinate more often, so avoid taking it at bedtime.
    • Can cause dizziness in the first few days.
    • Check your blood pressure 1 week after starting this medicine, and tell your doctor if it hasn't improved.
    • Tell your doctor about any dizziness, fatigue, or muscle weakness that doesn't go away.
    • Requires routine blood tests to check kidney function.
    • Tell your doctor about any dizziness, fatigue, cough, or throat irritation that doesn't go away.
    • Don't take it if you're pregnant.
    • Can cause dizziness in the first few days.
    • Check your blood pressure 1 week after starting this medicine, and tell your doctor if it hasn't improved.
    • Requires routine blood tests to check kidney function.
    • Can make you dizzy or cause trouble concentrating, so be careful using it until you know how the medicine affects you.
    • Don't use supplements or salt substitutes that are high in potassium.
    • You can have breast pain/swelling, irregular periods (women), or trouble with sexual performance.
    • Tell your doctor about any muscle weakness, skin changes, red or black tarry stool.
    • Can take 2 to 3 days to see full diuretic effects and 2 to 3 weeks to see blood pressure lowering effects.
    Coming soon.
    • Take it at the same time every day.
    • Drink plenty of water while taking this medicine.
    • Requires routine blood tests to make sure you have the right amount of Digoxin in your body.
    • Tell your doctor about other medicines you're taking to avoid drug interactions.
    Learn more
    More about HydrochlorothiazideSide effectsReviews & ratingsAlternativesFDA package insert
    More about LasixSide effectsReviews & ratingsFDA package insert
    More about LisinoprilSide effectsReviews & ratingsFDA package insert
    More about AldactoneSide effectsReviews & ratingsFDA package insert
    More about EdecrinSide effectsFDA package insert
    More about DigoxinSide effectsReviews & ratingsFDA package insert