Microzide Alternatives

(hydrochlorothiazide )

Alternatives

Compare Microzide (hydrochlorothiazide (HCTZ)) to alternatives

These medications are comparable to Microzide (hydrochlorothiazide (HCTZ)) or used for similar purposes.

Microzide
(hydrochlorothiazide )

Lasix
(Furosemide)

chlorthalidone

spironolactone

Edecrin
(Ethacrynic Acid)

Removes water from the body, which lowers blood pressure. Microzide (hydrochlorothiazide (HCTZ)) is a well-tolerated water pill that's often the first-choice treatment for mild high blood pressure.Lowers blood pressure. Removes extra water from your body. Lasix (Furosemide) is a very effective water pill and it'll certainly make you go to the bathroom more often.Lowers blood pressure. Removes extra water from your body. Thalitone (chlorthalidone) is a well-tolerated water pill that's increasingly used to treat high blood pressure.Removes extra water from your body. Aldactone (spironolactone) should be used with other medicines to get rid of excess fluid in your body, especially if you have heart failure.Coming soon.
Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
4.48hydrochlorothiazide
Reviews for hydrochlorothiazide
47%
of people (All ages) say hydrochlorothiazide is worth it
31%
say it works well
16%
say it's a big hassle
139 reviews
Have you used Microzide (hydrochlorothiazide (HCTZ))?
Worth itNot sureNot worth it
Reviews for Lasix
67%
-20% worse vs. hydrochlorothiazide
47%
-16% worse vs. hydrochlorothiazide
16%
Same vs. hydrochlorothiazide
371 reviews
Have you used Lasix (Furosemide)?
Worth itNot sureNot worth it

Not enough reviews for this treatment. Help someone out, leave a review!

Have you used Thalitone (chlorthalidone)?
Worth itNot sureNot worth it

Not enough reviews for this treatment. Help someone out, leave a review!

Have you used Aldactone (spironolactone)?
Worth itNot sureNot worth it

Not enough reviews for this treatment. Help someone out, leave a review!

Have you used Edecrin (Ethacrynic Acid)?
Worth itNot sureNot worth it
Side effects
hydrochlorothiazideLasixchlorthalidonespironolactoneEdecrin

The hydrochlorothiazide FDA package insert doesn’t have numbers about how common side effects are.

More about hydrochlorothiazide side effects »

The Lasix FDA package insert doesn’t have numbers about how common side effects are.

More about Lasix side effects »

The chlorthalidone FDA package insert doesn’t have numbers about how common side effects are.

More about chlorthalidone side effects »

The spironolactone FDA package insert doesn’t have numbers about how common side effects are.

More about spironolactone side effects »

We haven’t found good data for Edecrin side effects.

FDA side effect reports for Edecrin »
How it works
hydrochlorothiazideLasixchlorthalidonespironolactoneEdecrin
Microzide (hydrochlorothiazide (HCTZ)) is a thiazide diuretic (water pill) that makes you urinate more. It works in the kidneys to remove extra water and certain electrolytes, while lowering blood pressure and reducing swelling.Lasix (Furosemide) is a loop diuretic (water pill). It works in the kidneys to make you urinate more, which removes extra water and certain electrolytes. This lowers blood pressure and swelling.Thalitone (chlorthalidone) is a thiazide-like diuretic (water pill) that makes you urinate more. It works in the kidneys to remove extra water and certain electrolytes, while lowering blood pressure and reducing swelling.Aldactone (spironolactone) is a potassium-sparing diuretic that blocks aldosterone (a hormone) and helps the kidney get rid of excess fluids in your body.Coming soon.
Type of medication
hydrochlorothiazideLasixchlorthalidonespironolactoneEdecrin
Prescription onlyLower-cost generic availablePrescription onlyLower-cost generic availablePrescription onlyLower-cost generic availablePrescription onlyLower-cost generic availableNo lower cost generic available
Available as
hydrochlorothiazideLasixchlorthalidonespironolactoneEdecrin
  • Pill
  • Pill
  • Liquid
  • Pill
  • Pill
  • Pill
Used for
hydrochlorothiazideLasixchlorthalidonespironolactoneEdecrin
  • Edema
Risk factors for serious side effects
hydrochlorothiazideLasixchlorthalidonespironolactoneEdecrin
  • Current electrolyte imbalance
  • Lower kidney function
  • Dehydration
  • History of sulfa allergies
  • History of gout
Detailed Microzide (hydrochlorothiazide (HCTZ)) risks & warnings »
  • Current electrolyte imbalance
  • History of sulfa allergies
  • Current kidney problems
  • Dose too high
  • Low blood protein
Detailed Lasix (Furosemide) risks & warnings »
  • History of gout
  • History of diabetes
  • History of kidney disease
  • History of acute kidney failure
  • History of azotemia
Detailed Thalitone (chlorthalidone) risks & warnings »
  • Taking with alcohol
  • Taking other medicines that lower your blood pressure
  • Current kidney problems
  • Taking other medicines that increase potassium
  • Use of salt substitutes
Detailed Aldactone (spironolactone) risks & warnings »
    Coming soon.
    Pregnancy

    Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

    Kidneys and liver
    hydrochlorothiazideLasixchlorthalidonespironolactoneEdecrin
    • Requires routine blood tests to check kidney function.
    • Requires routine blood tests to check kidney function.
    • Thalitone (chlorthalidone) works on the kidneys to help increase the amount of fluids removed from the body. This also causes a loss of electrolytes. Your doctor will perform routine blood tests to monitor your electrolyte levels.
    • Thalitone (chlorthalidone) can increase the kidney's retention of uric acid, which can increase your risk of gouty attacks. Let your doctor know if you have a history of gout.
    • Thalitone (chlorthalidone) works on the kidneys. For people with a history of kidney problems, this can put more pressure on your kidneys and make it harder for them to work. Let your doctor know if you have a history of kidney disease.
    • Requires routine blood tests to check your kidney function.
    • You'll need to have blood tests done regularly since Aldactone (spironolactone) can affect your potassium levels and kidneys.
    No kidneys and liver related info.
    Pain
    hydrochlorothiazideLasixchlorthalidonespironolactoneEdecrin
    No pain related info.No pain related info.No pain related info.
    • It can cause breast pain/swelling, irregular periods (women), or trouble with sexual performance.
    No pain related info.
    Upsides and benefits
    hydrochlorothiazideLasixchlorthalidonespironolactoneEdecrin
    • Does a good job getting rid of extra fluids in your body by making you urinate more.
    • A first-choice blood pressure treatment. Works especially well for people of African descent.
    • Lowers the risk of heart attack and stroke.
    • Good option if you have high blood pressure and heart failure.
    • Most people have very few side effects from Microzide (hydrochlorothiazide (HCTZ)).
    • Can be good for patients with osteoporosis since it raises the body's level of calcium.
    • A strong diuretic (water pill) that works well to get rid of extra fluids in your body through urination.
    • Lowers your blood pressure and your risk of heart attack and stroke.
    • Works better than thiazide diuretics (like Hydrochlorothiazide) at removing harmful levels of certain electrolytes, such as potassium.
    • Okay to take if you have kidney problems.
    • Does a good job getting rid of extra fluids in your body by making you urinate more.
    • A good blood pressure treatment for people who haven't responded well to other thiazide diuretics. Works especially well for people of African descent.
    • Lowers the risk of heart attack and stroke.
    • Good option if you have high blood pressure and heart failure.
    • Can be good for patients with osteoporosis since it raises the body's level of calcium.
    • Has a low risk of causing muscle problems from low potassium levels in your blood.
    • More useful when taken with another diuretic that'll also help your body get rid of extra fluids.
    • Can lower blood pressure.
    • Reduces the risk of death in people with heart failure.
    Coming soon
    Downsides and risks
    hydrochlorothiazideLasixchlorthalidonespironolactoneEdecrin
    • Makes you urinate more often.
    • Microzide (hydrochlorothiazide (HCTZ)) doesn't work well in people with severe kidney problems.
    • It can increase the risk of gout attacks in people with poor kidney function or a history of gout.
    • People with a sulfa allergy may be allergic to Microzide (hydrochlorothiazide (HCTZ)).
    • Makes you urinate very frequently.
    • Can cause low levels of important electrolytes, such as potassium.
    • Makes you urinate more often.
    • Doesn't work well in people with severe kidney problems.
    • Since Thalitone (chlorthalidone) works longer in the body than other thiazide diuretics, it has a higher chance of causing electrolyte changes.
    • Thalitone (chlorthalidone) can lead to more gouty attacks in people with gout.
    • Don't use this if you have a sulfa allergy.
    • Aldactone (spironolactone) doesn't work well on its own. It should be used with another drug to help get rid of excess fluids.
    • Has many possible side effects, especially when higher doses are used.
    • Can increase the risk of tumor growth.
    • You'll need to have blood tests done regularly since Aldactone (spironolactone) can affect your potassium levels and kidneys.
    Coming soon
    Tips from our pharmacists for people taking the medication
    hydrochlorothiazideLasixchlorthalidonespironolactoneEdecrin
    • Microzide (hydrochlorothiazide (HCTZ)) starts working in about 2 hours.
    • It makes you urinate more often, so don't take it at bedtime.
    • Can cause dizziness in the first few days.
    • Check your blood pressure 1 week after starting this medicine, and tell your doctor if it hasn't improved.
    • Tell your doctor about any tiredness or muscle weakness that doesn't go away.
    • Requires routine blood tests to check kidney function.
    • Starts working in 30 minutes.
    • Makes you urinate more often, so avoid taking it at bedtime.
    • Can cause dizziness in the first few days.
    • Check your blood pressure 1 week after starting this medicine, and tell your doctor if it hasn't improved.
    • Tell your doctor about any dizziness, fatigue, or muscle weakness that doesn't go away.
    • Requires routine blood tests to check kidney function.
    • Take Thalitone (chlorthalidone) in the morning with a meal. It starts working in two hours, so don't take it at night; otherwise you'll go to the bathroom more overnight.
    • Can cause dizziness in the first few days.
    • Check your blood pressure 1 week after starting this medicine, and tell your doctor if it hasn't improved.
    • Tell your doctor about any dizziness, tiredness, or muscle weakness that doesn't go away.
    • Requires routine blood tests to check your kidney function.
    • Your skin will be more sensitive to the sun while taking this, so don't forget to use sunscreen.
    • Can make you dizzy or cause trouble concentrating, so be careful using it until you know how the medicine affects you.
    • Don't use supplements or salt substitutes that are high in potassium.
    • It can cause breast pain/swelling, irregular periods (women), or trouble with sexual performance.
    • Tell your doctor about any muscle weakness, skin changes, and red or black tarry stool.
    • You will urinate more often within 2 to 3 days, and will have lower blood pressure in 2 to 3 weeks.
    Coming soon
    Learn more
    More about hydrochlorothiazideSide effectsReviews & ratingsAlternativesFDA package insert
    Have you used Microzide (hydrochlorothiazide (HCTZ))?
    Worth itNot sureNot worth it
    More about LasixSide effectsReviews & ratingsFDA package insert
    Have you used Lasix (Furosemide)?
    Worth itNot sureNot worth it
    More about chlorthalidoneSide effectsReviews & ratingsFDA package insert
    Have you used Thalitone (chlorthalidone)?
    Worth itNot sureNot worth it
    More about spironolactoneSide effectsFDA package insert
    Have you used Aldactone (spironolactone)?
    Worth itNot sureNot worth it
    More about EdecrinSide effectsFDA package insert
    Have you used Edecrin (Ethacrynic Acid)?
    Worth itNot sureNot worth it