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Advil Alternatives

(Ibuprofen)

  • Pill
  • Chewable tablet
  • Oral suspension
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Compare Advil (Ibuprofen) to alternatives

These medications are comparable to Advil (Ibuprofen) or used for similar purposes.

Advil
(Ibuprofen)

Aleve
(Naproxen)

Mobic
(Meloxicam)

Aspirin

Tylenol Regular Strength
(Acetaminophen)

Celebrex
(Celecoxib)

Zorvolex
(Diclofenac)

Lodine
(Etodolac)

Relafen
(Nabumetone)

Relieves pain, fever, and inflammation. Advil (Ibuprofen) works well for mild to moderate pain and inflammation, but it doesn't last as long as other NSAIDs.Relieves pain, fever, and inflammation. Aleve (Naproxen) works well for mild to moderate pain and inflammation, and it lasts longer than other NSAIDs.Relieves pain and inflammation. Mobic (Meloxicam) works well for treating pain and causes less upset stomach than other NSAIDs.Relieves pain, fever, and inflammation. Protects your heart and thins blood. A low dose of Aspirin (81mg) every day can protect your heart, but it's not the best medicine to take for pain, swelling, or fever.Relieves pain and fever. Tylenol Regular Strength (Acetaminophen) reduces fever and relieves pain well, but it doesn't lower inflammation and swelling.Relieves pain and inflammation. Celebrex (Celecoxib) works well for treating pain and causes less upset stomach than other NSAIDs.Treats arthritis pain and swelling. Zorvolex (Diclofenac) is an okay medication used to treat pain and swelling caused by arthritis. However, because of the risk of heart attack, you should limit the amount you take.Coming soon.Coming soon.
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Reviews & ratings
Button Group. All currently active
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5.479768786127168Ibuprofen
Reviews for Advil (Ibuprofen)
88%
of people say Advil (Ibuprofen) is worth it
51%
say it works well
4%
say it's a big hassle
Reviews for Aleve (Naproxen)
78%
10% vs. Advil (Ibuprofen)
46%
5% vs. Advil (Ibuprofen)
5%
1% vs. Advil (Ibuprofen)
Reviews for Mobic (Meloxicam)
56%
32% vs. Advil (Ibuprofen)
48%
3% vs. Advil (Ibuprofen)
16%
12% vs. Advil (Ibuprofen)
Reviews for Aspirin
76%
12% vs. Advil (Ibuprofen)
41%
10% vs. Advil (Ibuprofen)
6%
2% vs. Advil (Ibuprofen)
Reviews for Tylenol Regular Strength (Acetaminophen)
77%
11% vs. Advil (Ibuprofen)
37%
14% vs. Advil (Ibuprofen)
3%
+1% vs. Advil (Ibuprofen)
Reviews for Celebrex (Celecoxib)
56%
32% vs. Advil (Ibuprofen)
36%
15% vs. Advil (Ibuprofen)
13%
9% vs. Advil (Ibuprofen)

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Side effects
IbuprofenNaproxenMeloxicamAspirinTylenolCelebrexDiclofenacLodineRelafen

We haven’t found good data for Ibuprofen side effects.

FDA side effect reports for Ibuprofen »

The Naproxen FDA package insert doesn’t have numbers about how common side effects are.

More about Naproxen side effects »
  • Gastrointestinal disorders 5%
  • Diarrhea 4%
  • Infection and infestations 3%
  • Accident household 3%
  • Swelling due to excess fluid 2%
  • Dyspeptic signs and symptoms 2%
  • Sore throat 2%
  • Dizziness 1%
  • Flu-like symptomsa-like symptoms 1%
More Meloxicam side effects »

We haven’t found good data for Aspirin side effects.

FDA side effect reports for Aspirin »

We haven’t found good data for Tylenol side effects.

FDA side effect reports for Tylenol »

We haven’t found good data for Celebrex side effects.

FDA side effect reports for Celebrex »
  • Constipation 4%
  • Diarrhea 3%
  • Abdominal pain upper 2%
  • Pain in extremity 2%
  • Itching 1%
  • Swelling due to excess fluid 1%
  • Passing gas 1%
More Diclofenac side effects »

We haven’t found good data for Lodine side effects.

FDA side effect reports for Lodine »

We haven’t found good data for Relafen side effects.

FDA side effect reports for Relafen »
How it works
IbuprofenNaproxenMeloxicamAspirinTylenolCelebrexDiclofenacLodineRelafen
Advil (Ibuprofen) is a non-steroidal anti-inflammatory drug (NSAID). It blocks the inflammation process in your body, which relieves swelling and pain.Aleve (Naproxen) is a non-steroidal anti-inflammatory drug (NSAID). It blocks the inflammation process in your body, which relieves swelling and pain.Mobic (Meloxicam) is a non-steroidal anti-inflammatory drug (NSAID). It blocks the inflammation process in your body, which relieves swelling and pain.Aspirin is a salicylate and non-steroidal anti-inflammatory drug (NSAID). It blocks the inflammation process in your body, which relieves swelling and pain. It also prevents blood platelets from forming clots, which thins your blood.Tylenol Regular Strength (Acetaminophen) reduces fever and relieves pain, but doesn't lower inflammation and swelling.Celebrex (Celecoxib) is a non-steroidal anti-inflammatory drug (NSAID). It blocks the inflammation process in your body, which relieves swelling and pain.Zorvolex (Diclofenac) is a non-steroidal anti-inflammatory drug (NSAID). It stops your body from making chemicals that cause inflammation and pain.Coming soon.Coming soon.
Type of medication
IbuprofenNaproxenMeloxicamAspirinTylenolCelebrexDiclofenacLodineRelafen
Pain reliever
Nonsteroidal anti-inflammatory drug (NSAID)
Prescription or OTC
Pain reliever
Nonsteroidal anti-inflammatory drug (NSAID)
Prescription or OTC
Pain reliever
Nonsteroidal anti-inflammatory drug (NSAID)
Prescription only
Pain reliever
Salicylate
Anticoagulant
Anti-platelet
Over-the-counter
Pain reliever
Acetaminophen (APAP)
Over-the-counter
Pain reliever
Nonsteroidal anti-inflammatory drug (NSAID)
Prescription only
Pain reliever
Nonsteroidal anti-inflammatory drug (NSAID)
Prescription only
Coming soon.
Coming soon.
Available as
IbuprofenNaproxenMeloxicamAspirinTylenolCelebrexDiclofenacLodineRelafen
  • Pill
  • Chewable tablet
  • Oral suspension
  • Pill
  • Delayed release tablet
  • Liquid
  • Pill
  • Liquid
  • Pill
  • Pill
  • Extended release tablet
  • Chewable tablet
  • Dissolving tablet
  • Gelcap
  • Liquid
  • Suppository
  • Pill
  • Pill
  • Pill
  • Extended release
  • Pill
Used for (click to learn more)
IbuprofenNaproxenMeloxicamAspirinTylenolCelebrexDiclofenacLodineRelafen
  • Osteoarthritis pain
  • Juvenile rheumatoid arthritis Osteoarthritis Pain Rheumatoid arthritis
  • Osteoarthritis Rheumatoid arthritis
Risk factors for serious side effects
IbuprofenNaproxenMeloxicamAspirinTylenolCelebrexDiclofenacLodineRelafen
  • History of heart problems
  • High blood pressure
  • High cholesterol
  • Diabetes
  • Smoking
  • History of stomach bleeding or ulcers
  • Age 60 years or older
  • Taking aspirin, NSAIDs, or blood thinners
  • Drinking more than 3 alcoholic beverages a day
  • Hemophilia
  • von Willebrand's disease
  • Low blood platelet count
  • Taking anticoagulant medications
  • Asthma
  • Rhinitis
  • Nasal polyps
  • Aspirin allergy
  • NSAID allergy
  • Kidney disease
  • Heart failure
  • Liver disease
  • Taking high blood pressure medications
  • Age 65 years or older
  • Women of childbearing age
Detailed Advil (Ibuprofen) risks & warnings »
Coming soon.Coming soon.Coming soon.Coming soon.Coming soon.Coming soon.Coming soon.Coming soon.
Pregnancy category
IbuprofenNaproxenMeloxicamAspirinTylenolCelebrexDiclofenacLodineRelafen
DFDA pregnancy category (Weigh risks vs. benefits)

Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

See the FDA package insert
CFDA pregnancy category (Weigh risks vs. benefits)

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

See the FDA package insert
DFDA pregnancy category (Weigh risks vs. benefits)

Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

See the FDA package insert
NFDA pregnancy category (Unknown)

The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

See the FDA package insert
NFDA pregnancy category (Unknown)

The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

See the FDA package insert
DFDA pregnancy category (Weigh risks vs. benefits)

Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

See the FDA package insert
DFDA pregnancy category (Weigh risks vs. benefits)

Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

See the FDA package insert
CFDA pregnancy category (Weigh risks vs. benefits)

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

See the FDA package insert
CFDA pregnancy category (Weigh risks vs. benefits)

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

See the FDA package insert
Alcohol
No specific alcohol-related info.No specific alcohol-related info.No specific alcohol-related info.No specific alcohol-related info.
  • Drinking alcohol while taking Tylenol Regular Strength (Acetaminophen) can damage your liver.
  • Heavy alcohol drinkers shouldn't use Tylenol Regular Strength (Acetaminophen) since it can cause serious liver damage.
No specific alcohol-related info.
  • You should avoid alcohol while on Zorvolex (Diclofenac) since it can increase your risk of stomach issues.
  • Don't drink alcohol while using Zorvolex (Diclofenac).
No specific alcohol-related info.No specific alcohol-related info.
Food
  • It needs to be taken with food to avoid getting an upset stomach.
  • Take it with a meal or a snack to prevent upset stomach.
  • It needs to be taken with food to avoid getting an upset stomach.
  • Take it with a meal or a snack to prevent an upset stomach.
  • Take Mobic (Meloxicam) only once a day. Take it with a meal or a snack to prevent an upset stomach.
  • Take with food to lower the chance of an upset stomach.
No specific food-related info.
  • Take it with a meal or a snack to prevent an upset stomach.
  • Take it with food to avoid getting diarrhea.
No specific food-related info.No specific food-related info.
Kidneys and liver
  • It can cause serious kidney and stomach problems (like ulcers and bleeding) the longer you take it.
  • Can hurt your kidneys, so don't use it if you have a history of kidney problems.
  • Advil (Ibuprofen) is an NSAID that can lower kidney function or cause damage. Taking the lowest dose for the shortest amount of time lowers your risk. Your doctor should check your kidney function if you take Advil (Ibuprofen) for any amount of time.
  • It can cause serious kidney and stomach problems (like ulcers and bleeding) the longer you take it.
  • Can hurt your kidneys, so don't use it if you have a history of kidney problems.
  • Can also affect your kidneys or cause permanent kidney damage if taken for a long time.
  • Can hurt your kidneys, so don't use it if you have a history of kidney problems.
No specific kidneys and liver-related info.
  • Doesn't cause kidney damage and is safe to use if you have heart problems or if you're pregnant.
  • Can also affect your kidneys or cause permanent kidney damage if taken for a long time.
  • Can hurt your kidneys, so don't use it if you have a history of kidney problems.
  • If you're taking it on a regular basis, you'll need to get labs done to make sure your liver and kidneys aren't being affected.
No specific kidneys and liver-related info.No specific kidneys and liver-related info.
Sex
No specific sex-related info.No specific sex-related info.No specific sex-related info.No specific sex-related info.No specific sex-related info.No specific sex-related info.No specific sex-related info.No specific sex-related info.No specific sex-related info.
Sleep
No specific sleep-related info.No specific sleep-related info.No specific sleep-related info.No specific sleep-related info.No specific sleep-related info.No specific sleep-related info.No specific sleep-related info.No specific sleep-related info.No specific sleep-related info.
Weight
No specific weight-related info.No specific weight-related info.No specific weight-related info.No specific weight-related info.No specific weight-related info.No specific weight-related info.No specific weight-related info.No specific weight-related info.No specific weight-related info.
Upsides and benefits
IbuprofenNaproxenMeloxicamAspirinTylenolCelebrexDiclofenacLodineRelafen
  • Ibuprofen works as well as aspirin in treating pain and causes fewer stomach problems.
  • Ibuprofen works better than acetaminophen (Tylenol) at lowering fever and relieving sinus pain.
  • Works well to relieve pain, swelling, and fevers.
  • Good for menstrual cramps, toothaches, body aches, and mild arthritis pain.
  • Although not without side effects, it's been around for a long time and is generally safe for short-term use.
  • Lasts longer than Ibuprofen, so you can take it less often.
  • Aleve (Naproxen) works as well as Aspirin and Indomethacin to treat arthritis pain, and causes fewer stomach problems.
  • Works well to relieve pain, swelling, and fevers.
  • Good for menstrual cramps, toothaches, body aches, and mild arthritis pain.
  • Although not without side effects, it's been around for a long time and is generally safe for short-term use.
  • Works well to relieve pain and inflammation from osteoarthritis, rheumatoid arthritis, and juvenile rheumatoid arthritis.
  • Good for muscle aches and pains.
  • It lasts longer than Ibuprofen, so you can take it less often.
  • Causes less upset stomach than other NSAIDs, like Ibuprofen.
  • Can also caus less bruising or bleeding than other NSAIDs when taken at lower doses (7.5 mg per day or less).
  • When taking low doses (81 mg) every day, Aspirin provides protection for your heart and prevents heart attacks and stroke.
  • Used in higher doses to relieve pain, swelling, and fever.
  • Available over-the-counter in drugstores by itself and in combination with other cold and flu medications.
  • Works well to relieve pain and fevers.
  • Tylenol Regular Strength (Acetaminophen) causes less upset stomach, ulcers, bruising, and bleeding than other pain medications like aspirin, ibuprofen, and naproxen.
  • Doesn't cause kidney damage and is safe to use if you have heart problems or if you're pregnant.
  • Good for menstrual cramps, toothaches, body aches, and mild arthritis pain.
  • Although not without side effects, it's been around for a long time and is generally safe for short-term use.
  • Relieves pain and inflammation for many types of arthritis, including osteoarthritis, rheumatoid arthritis, and juvenile rheumatoid arthritis.
  • Good for treating muscle aches and pains, as well as menstrual cramps.
  • Causes fewer stomach problems than other NSAIDs like Ibuprofen or Naproxen.
  • Lasts longer than Ibuprofen.
  • Clinical studies show that Zorvolex (Diclofenac) is better at relieving arthritis pain than acetaminophen (Tylenol).
  • Can be used as needed to treat pain and swelling.
  • Available as a generic.
Coming soon.Coming soon.
Downsides and risks
IbuprofenNaproxenMeloxicamAspirinTylenolCelebrexDiclofenacLodineRelafen
  • Ibuprofen doesn't work as long as other NSAIDs, so follow the package directions on how often you can take it.
  • It needs to be taken with food to avoid getting an upset stomach.
  • Can't be taken by pregnant women.
  • It can cause serious kidney and stomach problems (like ulcers and bleeding) the longer you take it.
  • Like all NSAIDs, it can raise your risk of having blood clots, heart attack, or stroke.
  • It needs to be taken with food to avoid getting an upset stomach.
  • Can't be taken by pregnant women.
  • It can cause serious kidney and stomach problems (like ulcers and bleeding) the longer you take it.
  • Like all NSAIDs, it can raise your risk of having blood clots, heart attack, or stroke.
  • The longer you take Mobic (Meloxicam), the more likely you are to have stomach problems, including inflammation, ulcers, and bleeding. This can also happen if you take Mobic (Meloxicam) on an empty stomach.
  • Like all NSAIDs, it can raise your risk of blood clots, heart attack, or a stroke.
  • Can also affect your kidneys or cause permanent kidney damage if taken for a long time.
  • Not a preferred medication for treating pain, swelling, or fever due to its high risk of bleeding.
  • NSAIDs (like ibuprofen and naproxen) and acetaminophen (Tylenol) are better for treating pain and fever thank Aspirin.
  • Aspirin raises your risk of bleeding, especially when used with other blood thinner medications like warfarin (Coumadin).
  • Studies show that using higher doses of Aspirin (162 mg or more) every day raises your risk of stomach bleeding and doesn't provide any additional heart protection.
  • Tylenol Regular Strength (Acetaminophen) doesn't treat pain as well as other medications like ibuprofen and naproxen.
  • Drinking alcohol while taking Tylenol Regular Strength (Acetaminophen) can damage your liver.
  • To avoid hurting your liver, you need to keep track of the total amount of acetaminophen (APAP) you are taking since it's a very common ingredient in pain and cold/flu combination medicines.
  • Heavy alcohol drinkers shouldn't use Tylenol Regular Strength (Acetaminophen) since it can cause serious liver damage.
  • The longer you take Celebrex (Celecoxib), the more likely you are to have stomach problems, including inflammation, ulcers, and bleeding. Can also happen if you take Celebrex (Celecoxib) on an empty stomach.
  • Like all NSAIDs, it can raise your risk of blood clots, heart attack, or a stroke.
  • Can also affect your kidneys or cause permanent kidney damage if taken for a long time.
  • You should avoid alcohol while on Zorvolex (Diclofenac) since it can increase your risk of stomach issues.
  • If you're taking it on a regular basis, you'll need to get labs done to make sure your liver and kidneys aren't being affected.
Coming soon.Coming soon.
Tips from our pharmacists for people taking the medication
IbuprofenNaproxenMeloxicamAspirinTylenolCelebrexDiclofenacLodineRelafen
  • Take it with a meal or a snack to prevent upset stomach.
  • Starts relieving pain in 30 to 60 minutes.
  • Can make you bruise or bleed more easily and it can also cause stomach ulcers.
  • Don't take it with other blood thinners, like aspirin, unless your doctor tells you it's safe.
  • Can hurt your kidneys, so don't use it if you have a history of kidney problems.
  • Starts relieving pain in 30 to 60 minutes.
  • Take it with a meal or a snack to prevent an upset stomach.
  • Can make you bruise or bleed more easily and it can also cause stomach ulcers.
  • Don't take it with other blood thinners, like aspirin, unless your doctor tells you it's safe.
  • Can hurt your kidneys, so don't use it if you have a history of kidney problems.
  • Take Mobic (Meloxicam) only once a day. Take it with a meal or a snack to prevent an upset stomach.
  • Can make you bruise or bleed more easily and it can also cause stomach ulcers.
  • Don't take it with other blood thinners, like aspirin, unless your doctor tells you it's safe.
  • Can hurt your kidneys, so don't use it if you have a history of kidney problems.
  • Using low doses (81mg) of Aspirin every day can lower your risk of heart attack and stroke, but it isn't good for everyone. Only take Aspirin daily if your doctor recommends it.
  • Higher Aspirin doses can be used to treat occasional pain, swelling, and fever. Using ibuprofen or acetaminophen (Tylenol) instead can lower your risk of serious bleeding.
  • Take with food to lower the chance of an upset stomach.
  • Don't use for kids younger than 18 years old.
  • Stop taking this right away and tell your doctor if you have ringing in your ears, unusual bleeding, or nausea or vomiting that doesn't go away.
  • Starts working in one hour.
  • Contains acetaminophen, also known as Tylenol or APAP. Taking too much can cause liver failure and death. Don't take more than what's recommended on the package or with other Tylenol-containing products.
  • Follow age-specific dosing instructions on how much to take. Adults should never take more than 3,000 milligrams (mg) in a single day.
  • Let your doctor know if your symptoms don't improve in a few days.
  • Starts working in 1 to 3 hours.
  • Take it with a meal or a snack to prevent an upset stomach.
  • Can make you bruise or bleed more easily and it can also cause stomach ulcers.
  • Don't take it with other blood thinners, like aspirin, unless your doctor tells you it's safe.
  • Can hurt your kidneys, so don't use it if you have a history of kidney problems.
  • Take it with food to avoid getting diarrhea.
  • Don't drink alcohol while using Zorvolex (Diclofenac).
  • Don't take other anti-inflammatory medications (NSAIDs) without talking to your doctor or pharmacist.
  • Can cause swelling in your legs, abdominal pain, constipation, diarrhea, and an upset stomach.
  • Don't take antacids with magnesium since they can interact with Zorvolex (Diclofenac).
  • Take Zorvolex (Diclofenac) at the smallest dose possible for the shortest amount of time to prevent an increased risk of heart attack.
Coming soon.Coming soon.
Learn more
More about IbuprofenSide effectsReviews & ratingsAlternativesFDA package insert
More about NaproxenSide effectsReviews & ratingsFDA package insert
More about MeloxicamSide effectsReviews & ratingsFDA package insert
More about AspirinSide effectsReviews & ratingsFDA package insert
More about TylenolSide effectsReviews & ratingsFDA package insert
More about CelebrexSide effectsReviews & ratingsFDA package insert
More about DiclofenacSide effectsReviews & ratingsFDA package insert
More about LodineSide effectsReviews & ratingsFDA package insert
More about RelafenSide effectsReviews & ratingsFDA package insert