Over-the-counterLower-cost generic availableClass: Pain

AdvilAlternatives

(ibuprofen)

Over-the-counterLower-cost generic availableClass: Pain
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Compare Advil (ibuprofen) to alternatives

These medications are comparable to Advil (ibuprofen) or used for similar purposes.

Advil
(ibuprofen)

Mobic
(meloxicam)

Tylenol Regular Strength
(acetaminophen)

Celebrex
(celecoxib)

Zorvolex
(diclofenac)

Lodine
(etodolac)

Relafen
(nabumetone)

Relieves pain, fever, and swelling. Advil (ibuprofen) works well for treating fever, inflammation, and a variety of mild to moderate pain conditions, but it doesn't last as long as other NSAIDs.Relieves pain and inflammation. Mobic (meloxicam) works well for pain and inflammation and you only take it once a day, but you need a prescription.Relieves pain and fever. Tylenol Regular Strength (Acetaminophen) reduces fever and relieves pain well, but it doesn't lower inflammation and swelling.Relieves pain and inflammation. Celebrex (Celecoxib) works well for treating pain and causes less upset stomach than other NSAIDs.Treats arthritis pain and swelling. Zorvolex (Diclofenac) is an okay medication used to treat pain and swelling caused by arthritis. However, because of the risk of heart attack, you should limit the amount you take.Coming soon.Coming soon.
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Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
5.49ibuprofen
Reviews for Advil (ibuprofen)
88%
of people (All ages) say Advil (ibuprofen) is worth it
52%
say it works well
4%
say it's a big hassle
892 reviews
Have you used Advil (ibuprofen)?
Worth itNot sureNot worth it
Reviews for Mobic (meloxicam)
64%
-24% worse vs. Advil (ibuprofen)
54%
+2% better vs. Advil (ibuprofen)
13%
-9% worse vs. Advil (ibuprofen)
141 reviews
Have you used Mobic (meloxicam)?
Worth itNot sureNot worth it
Reviews for Tylenol Regular Strength (acetaminophen)
77%
-11% worse vs. Advil (ibuprofen)
37%
-15% worse vs. Advil (ibuprofen)
3%
+1% better vs. Advil (ibuprofen)
1002 reviews
Have you used Tylenol Regular Strength (acetaminophen)?
Worth itNot sureNot worth it
Reviews for Celebrex (celecoxib)
57%
-31% worse vs. Advil (ibuprofen)
38%
-14% worse vs. Advil (ibuprofen)
14%
-10% worse vs. Advil (ibuprofen)
550 reviews
Have you used Celebrex (celecoxib)?
Worth itNot sureNot worth it

Not enough reviews for this drug. Help someone out, leave a review!

Have you used Zorvolex (diclofenac)?
Worth itNot sureNot worth it

Not enough reviews for this drug. Help someone out, leave a review!

Have you used Lodine (etodolac)?
Worth itNot sureNot worth it

Not enough reviews for this drug. Help someone out, leave a review!

Have you used Relafen (nabumetone)?
Worth itNot sureNot worth it
Side effects
ibuprofenmeloxicamTylenolCelebrexDiclofenacLodineRelafen

The ibuprofen FDA package insert doesn’t have numbers about how common side effects are.

More about ibuprofen side effects »
  • Indigestion 10%
  • Ear, nose, or throat infection 8%
  • Nausea 7%
  • Urinary tract infection 7%
  • Pain 5%
  • Abdominal pain 3%
  • Constipation 3%
  • Diarrhea 3%
  • Gas 3%
  • Vomiting 3%
More meloxicam side effects »

We haven’t found good data for Tylenol side effects.

FDA side effect reports for Tylenol »

We haven’t found good data for Celebrex side effects.

FDA side effect reports for Celebrex »
  • Swelling due to excess fluid 1%
  • Constipation 4%
  • Itching 1%
  • Passing gas 1%
  • Pain in extremity 2%
  • Indigestion 1%
More Diclofenac side effects »

We haven’t found good data for Lodine side effects.

FDA side effect reports for Lodine »

We haven’t found good data for Relafen side effects.

FDA side effect reports for Relafen »
How it works
ibuprofenmeloxicamTylenolCelebrexDiclofenacLodineRelafen
Advil (ibuprofen) is a non-steroidal anti-inflammatory drug (NSAID). It stops the inflammation process in your body, which relieves pain, swelling, and fever.Mobic (meloxicam) is a non-steroidal anti-inflammatory drug (NSAID). It blocks the inflammation process in your body, which relieves pain and swelling.Tylenol Regular Strength (Acetaminophen) reduces fever and relieves pain, but doesn't lower inflammation and swelling.Celebrex (Celecoxib) is a non-steroidal anti-inflammatory drug (NSAID). It blocks the inflammation process in your body, which relieves swelling and pain.Zorvolex (Diclofenac) is a non-steroidal anti-inflammatory drug (NSAID). It stops your body from making chemicals that cause inflammation and pain.Coming soon.Coming soon.
Type of medication
ibuprofenmeloxicamTylenolCelebrexDiclofenacLodineRelafen
Over-the-counter
Prescription only
Over-the-counter
Prescription only
Prescription only
Available as
ibuprofenmeloxicamTylenolCelebrexDiclofenacLodineRelafen
  • Pill
  • Chewable tablet
  • Suspension
  • Pill
  • Suspension
  • Pill
  • Extended release tablet
  • Chewable tablet
  • Dissolving tablet
  • Gelcap
  • Liquid
  • Suppository
  • Pill
  • Pill
  • Pill
  • Extended release
  • Pill
Used for
ibuprofenmeloxicamTylenolCelebrexDiclofenacLodineRelafen
  • Osteoarthritis Pain
  • Juvenile Rheumatoid Arthritis Osteoarthritis Pain Rheumatoid Arthritis
  • Osteoarthritis Rheumatoid Arthritis
Risk factors for serious side effects
ibuprofenmeloxicamTylenolCelebrexDiclofenacLodineRelafen
  • History of heart problems
  • Taking Advil (ibuprofen) for a long period of time
  • History of stomach bleeding
  • Age 60 or older
  • Taking aspirin, other NSAIDs, or blood thinners
  • Drinking more than 3 alcoholic beverages a day
  • Smoking
  • Taking the medicine for a long period of time
  • Asthma
  • Nasal polyps
  • Aspirin allergy
  • NSAID allergy
  • Kidney disease
  • Heart failure
  • Liver disease
  • Taking certain high blood pressure medications
  • Age 60 or older
  • Taking the medicine for a long period of time
  • Women who want to or can become pregnant
  • Pregnant women
Detailed Advil (ibuprofen) risks & warnings »
  • History of heart problems
  • Taking the medicine for a long period of time
  • History of stomach bleeding
  • Age 60 or older
  • Taking aspirin, other NSAIDs, or blood thinners
  • Drinking more than 3 alcoholic beverages a day
  • Smoking
  • Taking the medicine for a long time
  • Asthma
  • Nasal polyps
  • Aspirin allergy
  • NSAID allergy
  • Kidney disease
  • Heart failure
  • Liver disease
  • Taking certain high blood pressure medications
  • Age 60 or older
  • Taking the medicine for a long period of time
  • Women who want to or can become pregnant
  • Pregnant women
Detailed Mobic (meloxicam) risks & warnings »
  • Drinking more than 2 alcoholic beverages a day
  • Taking with other Tylenol-containing medicines
  • History of liver disease
Detailed Tylenol Regular Strength (acetaminophen) risks & warnings »
  • Long-term use
  • History of heart disease
  • History of heart bypass surgery (coronary artery bypass graft/CABG)
  • Age 65 or older
  • History of GI bleed or peptic ulcer disease
  • History of high blood pressure
  • Taking water pills (diuretics)
  • History of heart failure
    • History of asthma
    • Kidney Disease
    • Heart Failure
    • Liver Disease
    • Also taking diuretics
    • Also taking ACE inhibitors
    • Also taking Angiotensin Receptor Blockers (ARBs)
    • Age 65 or older
    • Late pregnancy (more than 30 weeks)
    Detailed Celebrex (celecoxib) risks & warnings »
    • History of heart problems
    • High blood pressure
    • High cholesterol
    • Diabetes
    • Being overweight or obese
    • Smoking
    • History of stomach bleeding or ulcers
    • Age 65 years or older
    • Bleeding disorder
    • Taking other blood-thinning medications
    • Asthma
    • Rhinitis
    • Nasal polyps
    • Aspirin allergy
    • NSAID allergy
    • Kidney problems
    • Heart failure
    • Liver disease
    • Taking diuretics
    • Taking ACE inhibitors or angiotensin receptor blockers (ARBs)
    • Age 65 or older
    • History of high blood pressure
    • Taking water pills (diuretics)
    Detailed Zorvolex (diclofenac) risks & warnings »
    Coming soon.Coming soon.
    Pregnancy

    The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

    Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    Alcohol
    ibuprofenmeloxicamTylenolCelebrexDiclofenacLodineRelafen
    No alcohol related info.No alcohol related info.
    • Drinking alcohol while taking Tylenol Regular Strength (Acetaminophen) can damage your liver.
    • Heavy alcohol drinkers shouldn't use Tylenol Regular Strength (Acetaminophen) since it can cause serious liver damage.
    No alcohol related info.
    • You should avoid alcohol while on Zorvolex (Diclofenac) since it can increase your risk of stomach issues.
    • Don't drink alcohol while using Zorvolex (Diclofenac).
    No alcohol related info.No alcohol related info.
    Food
    ibuprofenmeloxicamTylenolCelebrexDiclofenacLodineRelafen
    • It needs to be taken with food or millk to avoid getting an upset stomach.
    • Take it with food or milk to prevent stomach upset.
    • It should be taken only once a day, with food or milk to prevent stomach upset.
    No food related info.
    • Take it with a meal or a snack to prevent an upset stomach.
    • Take it with food to avoid getting diarrhea.
    No food related info.No food related info.
    Kidneys and liver
    ibuprofenmeloxicamTylenolCelebrexDiclofenacLodineRelafen
    • Advil (ibuprofen) can damage your kidneys. Taking the lowest dose for the shortest amount of time lowers your risk. Talk to your doctor if this worries you, or if you already have kidney damage before you start taking Advil (ibuprofen).
    • Mobic (meloxicam) can damage your kidneys if you take it for a very long time. Taking the lowest dose for the shortest amount of time lowers your risk. Talk to your doctor if this worries you, or if you already have kidney damage before you start taking Mobic (meloxicam).
    • Doesn't cause kidney damage and is safe to use if you have heart problems or if you're pregnant.
    • To avoid hurting your liver, you need to keep track of the total amount of acetaminophen (APAP) you are taking since it's a very common ingredient in pain and cold/flu combination medicines.
    • Can also affect your kidneys or cause permanent kidney damage if taken for a long time.
    • Can hurt your kidneys, so don't use it if you have a history of kidney problems.
    • Celebrex (Celecoxib), and similar medications in the NSAID family, can cause lower kidney function or cause permanent kidney damage. You're at higher risk for this if you've a history of kidney disease, heart failure, and liver disease. Taking Diuretic, ACE inhibitor, or Angiotensin Receptor Blocker (ARB) medications also increases your risk. If you are 65 or older you're also at a higher risk for these types of kidney problems.
    • Zorvolex (Diclofenac), and similar medications in the NSAID family, can lower kidney function or cause permanent kidney damage. Taking the lowest dose for the shortest amount of time necessary can lower your risk of kidney problems. It's important to get lab tests to check your kidney function periodically if you use Zorvolex (Diclofenac) for long periods of time.
    No kidneys and liver related info.No kidneys and liver related info.
    Pain
    ibuprofenmeloxicamTylenolCelebrexDiclofenacLodineRelafen
    • Good for relieving pain due to common conditions like menstrual cramps, toothaches, backaches, and sports-related injuries.
    • Do not take for more than 10 days for pain relief or more than 3 days for fever. Talk to your doctor if your symptoms do not go away.
    • Works well to relieve pain and inflammation due to osteoarthritis, rheumatoid arthritis, and juvenile rheumatoid arthritis.
    • Mobic (meloxicam) can cause stomach bleeding which can be dangerous. If you notice blood in your vomit or your stool has bright red blood or looks like black coffee grounds, or if you have pain in your stomach that doesn't go away, talk to your doctor right away.
    • Works well to relieve pain and fevers.
    • To avoid hurting your liver, you need to keep track of the total amount of acetaminophen (APAP) you are taking since it's a very common ingredient in pain and cold/flu combination medicines.
    • Relieves pain and inflammation for many types of arthritis, including osteoarthritis, rheumatoid arthritis, and juvenile rheumatoid arthritis.
    • Good for treating muscle aches and pains, as well as menstrual cramps.
    • Can hurt your kidneys, so don't use it if you have a history of kidney problems.
    • Clinical studies show that Zorvolex (Diclofenac) is better at relieving arthritis pain than acetaminophen (Tylenol).
    • Can be used as needed to treat pain and swelling.
    • Can cause swelling in your legs, abdominal pain, constipation, diarrhea, and an upset stomach.
    No pain related info.No pain related info.
    Upsides and benefits
    ibuprofenmeloxicamTylenolCelebrexDiclofenacLodineRelafen
    • Advil (ibuprofen) is effective for treating fever, pain, and inflammation.
    • Good for relieving pain due to common conditions like menstrual cramps, toothaches, backaches, and sports-related injuries.
    • Advil (ibuprofen) is generally safe to use, cheap, and available over-the-counter.
    • Advil (ibuprofen) causes less stomach problems than its alternatives.
    • It comes in different flavored liquid forms that makes it easy for children to take.
    • Taken only once a day, while other NSAIDS need to be taken a few times a day for the same effect.
    • Works well to relieve pain and inflammation due to osteoarthritis, rheumatoid arthritis, and juvenile rheumatoid arthritis.
    • Causes less stomach upset than other NSAIDs.
    • Relatively cheap compared to other prescription NSAIDS.
    • Works well to relieve pain and fevers.
    • Good for menstrual cramps, toothaches, body aches, and mild arthritis pain.
    • Tylenol Regular Strength (Acetaminophen) causes less upset stomach, ulcers, bruising, and bleeding than other pain medications like aspirin, ibuprofen, and naproxen.
    • Doesn't cause kidney damage and is safe to use if you have heart problems or if you're pregnant.
    • Although not without side effects, it's been around for a long time and is generally safe for short-term use.
    • Relieves pain and inflammation for many types of arthritis, including osteoarthritis, rheumatoid arthritis, and juvenile rheumatoid arthritis.
    • Good for treating muscle aches and pains, as well as menstrual cramps.
    • Causes fewer stomach problems than other NSAIDs like Ibuprofen or Naproxen.
    • Lasts longer than Ibuprofen.
    • Clinical studies show that Zorvolex (Diclofenac) is better at relieving arthritis pain than acetaminophen (Tylenol).
    • Can be used as needed to treat pain and swelling.
    • Available as a generic.
    Coming soonComing soon
    Downsides and risks
    ibuprofenmeloxicamTylenolCelebrexDiclofenacLodineRelafen
    • Advil (ibuprofen) doesn't last as long as other NSAIDs, so you need to take it a few times a day to get relief of your symptoms.
    • It needs to be taken with food or millk to avoid getting an upset stomach.
    • Advil (ibuprofen) is not as safe as other alternatives for pregnant women and people who are age 60 or older.
    • It can cause serious complications like stomach bleeding and kidney problems if taken for a long period of time.
    • Like all NSAIDs, Advil (ibuprofen) can raise your risk of getting blood clots, a heart attack, or stroke.
    • Mobic (meloxicam) does not kick in as fast as other NSAIDS.
    • It's available by prescription only.
    • Mobic (meloxicam) is not as safe as other alternatives for pregnant women and people who are age 60 or older.
    • It can cause serious complications like stomach bleeding and kidney problems if taken for a long time.
    • Tylenol Regular Strength (Acetaminophen) doesn't treat pain as well as other medications like ibuprofen and naproxen.
    • Drinking alcohol while taking Tylenol Regular Strength (Acetaminophen) can damage your liver.
    • To avoid hurting your liver, you need to keep track of the total amount of acetaminophen (APAP) you are taking since it's a very common ingredient in pain and cold/flu combination medicines.
    • Heavy alcohol drinkers shouldn't use Tylenol Regular Strength (Acetaminophen) since it can cause serious liver damage.
    • The longer you take Celebrex (Celecoxib), the more likely you are to have stomach problems, including inflammation, ulcers, and bleeding. Can also happen if you take Celebrex (Celecoxib) on an empty stomach.
    • Like all NSAIDs, it can raise your risk of blood clots, heart attack, or a stroke.
    • Can also affect your kidneys or cause permanent kidney damage if taken for a long time.
    • You should avoid alcohol while on Zorvolex (Diclofenac) since it can increase your risk of stomach issues.
    • If you're taking it on a regular basis, you'll need to get labs done to make sure your liver and kidneys aren't being affected.
    Coming soonComing soon
    Tips from our pharmacists for people taking the medication
    ibuprofenmeloxicamTylenolCelebrexDiclofenacLodineRelafen
    • Starts working in about 30 to 60 minutes.
    • Take it with food or milk to prevent stomach upset.
    • Do not take for more than 10 days for pain relief or more than 3 days for fever. Talk to your doctor if your symptoms do not go away.
    • If you normally take a daily aspirin, make sure to take Advil (ibuprofen) at least 30 minutes after taking aspirin or more than 8 hours before taking aspirin. This will help make sure the aspirin still works in your body.
    • Advil (ibuprofen) increases the risk of stomach bleeding so tell your doctor right away if you experience any bleeding.
    • If you are allergic to aspirin, there is a chance you may be allergic to Advil (ibuprofen) as well.
    • It should be taken only once a day, with food or milk to prevent stomach upset.
    • Mobic (meloxicam) increases the risk of stomach bleeding so tell your doctor right away if you experience any bleeding.
    • Do not take Mobic (meloxicam) with any blood thinners unless your doctor says so.
    • If you are allergic to aspirin, you may be allergic to Mobic (meloxicam) as well.
    • The capsule, suspension, and tablet forms of the medicine come in different strengths, so be careful when switching from one form to another.
    • Starts working in one hour.
    • Contains acetaminophen, also known as Tylenol or APAP. Taking too much can cause liver failure and death. Don't take more than what's recommended on the package or with other Tylenol-containing products.
    • Follow age-specific dosing instructions on how much to take. Adults should never take more than 3,000 milligrams (mg) in a single day.
    • Let your doctor know if your symptoms don't improve in a few days.
    • Starts working in 1 to 3 hours.
    • Take it with a meal or a snack to prevent an upset stomach.
    • Can make you bruise or bleed more easily and it can also cause stomach ulcers.
    • Don't take it with other blood thinners, like aspirin, unless your doctor tells you it's safe.
    • Can hurt your kidneys, so don't use it if you have a history of kidney problems.
    • Take it with food to avoid getting diarrhea.
    • Don't drink alcohol while using Zorvolex (Diclofenac).
    • Don't take other anti-inflammatory medications (NSAIDs) without talking to your doctor or pharmacist.
    • Can cause swelling in your legs, abdominal pain, constipation, diarrhea, and an upset stomach.
    • Don't take antacids with magnesium since they can interact with Zorvolex (Diclofenac).
    • Take Zorvolex (Diclofenac) at the smallest dose possible for the shortest amount of time to prevent an increased risk of heart attack.
    Coming soonComing soon
    Learn more
    More about ibuprofenSide effectsReviews & ratingsAlternativesFDA package insert
    Have you used Advil (ibuprofen)?
    Worth itNot sureNot worth it
    More about meloxicamSide effectsReviews & ratingsFDA package insert
    Have you used Mobic (meloxicam)?
    Worth itNot sureNot worth it
    More about TylenolSide effectsReviews & ratingsFDA package insert
    Have you used Tylenol Regular Strength (acetaminophen)?
    Worth itNot sureNot worth it
    More about CelebrexSide effectsReviews & ratingsFDA package insert
    Have you used Celebrex (celecoxib)?
    Worth itNot sureNot worth it
    More about DiclofenacSide effectsReviews & ratingsFDA package insert
    Have you used Zorvolex (diclofenac)?
    Worth itNot sureNot worth it
    More about LodineSide effectsReviews & ratingsFDA package insert
    Have you used Lodine (etodolac)?
    Worth itNot sureNot worth it
    More about RelafenSide effectsReviews & ratingsFDA package insert
    Have you used Relafen (nabumetone)?
    Worth itNot sureNot worth it