Prescription onlyLower-cost generic availableClass: Cardiovascular


(isosorbide mononitrate)

Prescription onlyLower-cost generic availableClass: Cardiovascular
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Relieves chest pain.

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Our bottom line

Isosorbide mononitrate is good for chest pain, but you have to be able to stick to your dosing schedule or it won't work as well.

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  • Prevents heart-related chest pain (angina) from the narrowing of heart blood vessels (coronary artery disease).
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  • You can develop tolerance to this medicine over time, which means that the same dose becomes less effective. You have to stick to a really specific dosing schedule to prevent this from happening.
  • Headaches are normal with this medicine and they go away as your body gets used to it, but they can be severe or not tolerable for some people.
How it works

Isosorbide mononitrate is a nitrate. It dilates blood vessels all over the body. This makes it less work for the heart to pump, which relieves heart-related chest pain.

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Side effect rates for Imdur (isosorbide mononitrate)

156 From clinical trials of Imdur / Angina (Extended release 30mg)
  • Headache
  • Dizziness

Risks and Warnings for Imdur (isosorbide mononitrate)

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    • Higher risk if:
    • Concurrent use of erectile dysfunction medicine
    • Age 65 years or older
    • Alcohol use

    Don't use Imdur (Isosorbide Mononitrate) with an erectile dysfunction medicine without talking to your doctor. You can feel dizzy or fall from a sudden drop in blood pressure when you change positions, such as going from sitting to standing. This is called orthostatic hypotension. If you're sensitive to low blood pressure, change position slowly until your body is used to the medicine. If you continue to feel dizzy or have episodes of fast heart rate a week after using Imdur (Isosorbide Mononitrate), dose adjustment or a different medication may be needed.

Common concerns from people taking Imdur (isosorbide mononitrate)

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  • Don't drink alcohol while taking this medicine. It can make you really dizzy.