Treats pain and swelling.
Our pharmacists’ bottom line
Indocin (Indomethacin) works well for mild to moderate pain and swelling, but it shouldn't be used long-term since it has some serious side effects.
- Effective option to relieve mild to moderate pain and swelling.
- Treats inflammation problems, such as rheumatoid arthritis, osteoarthritis, and acute gout attacks.
- In studies, Indocin (Indomethacin) was more effective than Tylenol for treating osteoarthritis pain.
- It works as well as Celebrex for treating an acute gout attacks.
- Available in capsules, long-acting capsules, suppositories, and as a suspension. All forms, except the suspension, are available as generic medications.
- Indocin (Indomethacin) can cause serious heart and stomach problems. The risk goes up the longer you take it, but problems can happen at any time. Don't take Indocin (Indomethacin) any longer than your doctor recommends.
- Indocin (Indomethacin) raises your risk of bleeding, especially when taken with other blood-thinning medicines.
- There are similar medicines that you don't have to take as often and can work just as well.
- Not a good choice if you have kidney, liver, or stomach problems.
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Side effects for Indocin (Indomethacin)
From clinical trials of Indocin / Mild to moderate acute pain (20 mg) ( 371)
- NauseaNausea34% for Indomethacin vs.36% for placebo
- Post procedural edemaPost procedural edema26% for Indomethacin vs.32% for placebo
- VomitingVomiting12% for Indomethacin vs.11% for placebo
- HeadacheHeadache11% for Indomethacin vs.11% for placebo
- DizzinessDizziness10% for Indomethacin vs.17% for placebo
- ConstipationConstipation6% for Indomethacin vs.5% for placebo
- Post procedural hemorrhagePost procedural hemorrhage5% for Indomethacin vs.6% for placebo
- ItchingItching4% for Indomethacin vs.0% for placebo
- DiarrheaDiarrhea2% for Indomethacin vs.1% for placebo
- RashRash2% for Indomethacin vs.0% for placebo
What to expect when you start Indocin (Indomethacin)Skip what to expect section. Skip to Risks & Warnings section.
- Takes about 30 minutes to start working and can last about 4 to 6 hours.
- Can cause stomach ulcers or bleeding. Don't take it with other blood-thinning medicines without talking to your doctor first.
- Can cause headaches. If the headaches continue even after you take a lower dose, talk to your doctor about stopping Indocin (Indomethacin).
- The long-acting capsules must be swallowed whole. Don't crush them.
- Take with food or milk to help prevent upset stomach.
Risks and Warnings for Indocin (Indomethacin)Skip Risks and Warnings section. Skip to Tips section.
- Higher risk if:
- › History of cardiovascular disease
- › High blood pressure
- › Smoking
Indocin (Indomethacin) can increase your chance of having blood clots, heart attack, or stroke. The risk can increase the longer you take it. Talk to your doctor about taking the lowest dose that works for you for the shortest time possible.
This is a black box warning. The FDA requires this warning when there is a significant risk of serious or life-threatening effects that anyone taking the drug should consider.
Tips from pharmacists and people taking Indocin (Indomethacin)Final section. Do you want to return to drug navigation?
- Tips from our pharmacists
- › Take with food or milk to help prevent upset stomach.
- always take with foodAge: 38Gender: womanTaken for: cluster headachesDuration taken: a month or so
- Make sure you take with food. I made the mistake of not and could not function at work.Age: 29Gender: womanTaken for: Gouty arthritis
- Upsides and downsides from our pharmacists
- › Not a good choice if you have kidney, liver, or stomach problems.
- Risks from our pharmacists
- › Indocin (Indomethacin) is processed by the kidney and liver. If you have kidney or liver problems, talk to your doctor because you may need a different dose. (No dose adjustments are specified on the manufacturer's label.)