Inspra

(eplerenone)

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Helps lower blood pressure and protect the heart in people with heart failure.

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Our bottom line

Inspra (eplerenone) lowers blood pressure and can help remove fluid when it's used with other drugs. It reduces the risk of death in people with heart failure and is usually used when people can't take spironolactone.

Quick facts about Inspra
  • Drug class: Cardiovascular
  • Rx status: Prescription only
  • Generic status: Lower-cost generic available (eplerenone)
Prices and discounts
Lowest price for 30 25mg tablets
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$39.26

Upsides

  • Lowers your blood pressure.
  • It can help remove fluid from your body when it's used with other drugs.
  • Reduces the risk of death in people with heart failure.
  • It can have fewer side effects than spironolactone.

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What to expect from Inspra, on one page

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Downsides

  • Inspra (eplerenone) isn't a first choice medicine for lowering blood pressure or getting rid of fluid in the body. It's usually used in combination with other medicines.
  • It can make you feel dizzy for the first few days. Be careful driving until you know how it affects you.
  • You'll need to have blood tests done regularly since Inspra (eplerenone) can affect your potassium levels and kidney function.
  • It can be very expensive compared to spironolactone.

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Sign up and get Pill Talk, the latest in health & medicine news from Iodine

Get our free fact sheet

What to expect from Inspra, on one page

Download Fact Sheet
Prices and discounts
Lowest price for 30 25mg tablets
Determining your location...
$39.26
How it works

Inspra (eplerenone) is an aldosterone antagonist. It blocks aldosterone (a hormone) and helps your kidneys get rid of excess fluid in your body, which helps lower blood pressure.

Quick facts about Inspra
  • Drug class: Cardiovascular
  • Rx status: Prescription only
  • Generic status: Lower-cost generic available (eplerenone)

Dosage forms

  • Pill
Tried Inspra? Write a review!

What to expect when you take Inspra (eplerenone) for High blood pressure

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Side effect rates for Inspra (eplerenone)

From 6608 clinical trials of Inspra when taken for heart failure
  • High potassium
  • Abnormal renal function

Risks and Warnings for Inspra (eplerenone)

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    • Higher risk if:
    • Taking with alcohol
    • Taking other medicines that lower your blood pressure

    Inspra (eplerenone) lowers your blood pressure and can make you feel lightheaded or dizzy. This should go away after a few days, but talk to your doctor if it doesn't. They may change your dose or put you on a different medication.

Common concerns from people taking Inspra (eplerenone)

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Pregnancy
Kidneys and liver
  • Inspra (eplerenone) shouldn't be used by people with bad kidneys since it can hurt your kidneys or cause worse side effects, such as high potassium levels. Your doctor will do frequent blood tests to monitor your kidney function and electrolytes while you're on this drug.
  • Shouldn't be used by people with kidney or liver damage.
  • You'll need to have blood tests done regularly since Inspra (eplerenone) can affect your potassium levels and kidney function.