Isentress

(raltegravir)

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Works with other medicications to treat HIV infection.

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Our bottom line

Isentress (raltegravir) is considered a first choice to be used with other medications for treating HIV, but it can have more side effects than other similar medicines.

Quick facts about Isentress
  • Drug class: Infection
  • Rx status: Prescription only
  • Generic status: No lower cost generic available
Prices and discounts
Lowest price for 60 400mg tablets
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$1424.38

Upsides

  • Isentress (raltegravir) is a first choice treatment to use together with other medications to treat HIV.
  • If you have difficulty swallowing the tablet, there is a chewable tablet or oral suspension available.
  • Can be used by children 4 weeks and older.
  • People with mild to moderate kidney or liver damage can use Isentress (raltegravir).
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Downsides

  • It might be hard to remember to take Isentress (raltegravir) two times a day. Other similar medicines are once a day.
  • The chewable tablets contain phenylalanine and should be avoided in people who have phenylketonuria.
  • Isentress (raltegravir) cannot be used alone to treat or prevent HIV. It must be used together with other medications.
  • Not available as part of a combination tablet, so you'll have to take more tablets daily compared to other combinations.
Prices and discounts
Lowest price for 60 400mg tablets
Determining your location...
$1424.38
How it works

Isentress (raltegravir) is an integrase inhibitor. It treats or prevents HIV by stopping the virus from reproducing within cells in your immune system.

Quick facts about Isentress
  • Drug class: Infection
  • Rx status: Prescription only
  • Generic status: No lower cost generic available

Used for

Dosage forms

  • Pill
  • Chewable tablet
  • Liquid
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What to expect when you take Isentress (raltegravir) for HIV treatment

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Side effect rates for Isentress (raltegravir)

281 
From clinical trials of Isentress / HIV treatment (400mg)
  • Headache
  • Insomnia
  • Nausea
  • Fatigue
  • Dizziness

Risks and Warnings for Isentress (raltegravir)

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    • Higher risk if:
    • Prior severe allergic reaction to Isentress

    Some people taking Isentress (raltegravir) have had severe and potentially life-threatening skin reactions. If you suddenly get a high fever, blistering rash all over your body, oral lesions, or trouble breathing, go to the emergency room right away.

Common concerns from people taking Isentress (raltegravir)

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Kidneys and liver
  • People with mild to moderate kidney or liver damage can use Isentress (raltegravir).
Pain
  • Isentress (raltegravir) might cause muscle pain, weakness, or damage in some patients, which can also cause kidney damage if it's not caught in time. If you have any of these symptoms or notice dark urine, to your doctor immediately.