Prescription onlyLower-cost generic available

Isordil

(Isosorbide Dinitrate)

  • Pill
  • Extended release
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Relieves chest pain.

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Prescription onlyLower-cost generic available

Our pharmacists’ bottom line

Isosorbide dinitrate is good for chest pain, but you have to be able to stick to your dosing schedule or it won't work as well.

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  • Treats and prevents heart-related chest pain (angina) from the narrowing of heart blood vessels (coronary artery disease).
  • You can develop tolerance to this medicine over time, which means that the same dose becomes less effective. You have to stick to a really specific dosing schedule to prevent this from happening.
  • Headaches are normal with this medicine and they go away as your body gets used to it, but they can be severe or not tolerable for some people.

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Side effects for Isordil (Isosorbide Dinitrate)

Manufacturers don’t say how common these side effects are

  • Crescendo angina
  • Fainting
  • Headache
  • Lightheadedness
  • Low blood pressure
  • Rebound hypertension

What to expect when you take Isordil (Isosorbide Dinitrate)

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Tips from our pharmacists
  • Can cause headaches, dizziness, lightheadedness, or fainting.
  • Don't drink alcohol while taking this medicine. It can make you really dizzy.
  • Tell your doctor if you're taking any medicine for erectile dysfunction.
  • Don't stop taking this medicine suddenly.

Risks and Warnings for Isordil (Isosorbide Dinitrate)

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    • Higher risk if:
    • Age 65 years or older
    • Taking drugs for erectile dysfunction
    • Alcohol use

    Dizziness and falls may occur due to a sudden drop in blood pressure when you change positions, like from lying down or sitting to standing. This is called orthostatic hypotension. If you're sensitive to low blood pressure, change position slowly until your body is used to the medicine. If symptoms continues for more than a week, talk to your doctor. Also tell your doctor if you are taking any drugs for erectile dysfunction, as this can increase the likelihood of dizziness or falls. Drinking alcohol while on this medication may also increase the risk of dizziness or falling.

Means that some groups have a high risk of experiencing this side effect

Tips from pharmacists and people taking Isordil (Isosorbide Dinitrate)

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The FDA category for this medication is C. It is advised that you: Weigh risks vs. benefits
Pregnancy
Alcohol
  • Tips from our pharmacists
  • Don't drink alcohol while taking this medicine. It can make you really dizzy.
  • Risks from our pharmacists
  • Dizziness and falls may occur due to a sudden drop in blood pressure when you change positions, like from lying down or sitting to standing. This is called orthostatic hypotension. If you're sensitive to low blood pressure, change position slowly until your body is used to the medicine. If symptoms continues for more than a week, talk to your doctor. Also tell your doctor if you are taking any drugs for erectile dysfunction, as this can increase the likelihood of dizziness or falls. Drinking alcohol while on this medication may also increase the risk of dizziness or falling.