Prescription onlyNo lower cost generic available

Januvia

(Sitagliptin)

  • Pill
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Lowers blood sugar.

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Prescription onlyNo lower cost generic available

Our pharmacists’ bottom line

Januvia (Sitagliptin) is a good add-on treatment if your blood sugar is still too high, but you don't want to use an injectable medicine.

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  • Oral blood sugar-lowering medicine.
  • Lowers A1c levels by 0.5-0.8%. (Hemoglobin A1c measures your average blood sugar over time.)
  • Prevents the harmful effects of high sugar levels on your organs and blood vessels.
  • Uses the hormones naturally produced by your body to affect how sugar is processed.
  • Unlike some diabetes medicines, it's unlikely to cause weight gain and low blood sugar.
  • You don't have to check your blood sugar every day with this medicine.
  • Not as strong as other diabetes medicines. Your doctor might add it to your blood sugar-lowering regimen if your sugar levels are still too high.
  • Likely expensive since there's no generic version available.
  • Some people might get frequent throat infections or nasal congestion.

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Side effects for Januvia (Sitagliptin)

From clinical trials of Januvia / Type 2 diabetes 

  • DiarrheaDiarrhea3% for Januvia vs.2% for placebo
  • Abdominal painAbdominal pain2% for Januvia vs.2% for placebo
  • NauseaNausea1% for Januvia vs.1% for placebo
  • Low blood sugarLow blood sugar1% for Januvia vs.1% for placebo

What to expect when you take Januvia (Sitagliptin) for Improves blood sugar levels

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Tips from our pharmacists
  • Can cause headache and cold-like symptoms.
  • Tell your doctor about persistent stomach pain, nausea, vomiting, or loss of appetite.
  • Can be expensive depending on insurance coverage.
  • Check your blood sugar regularly.

Risks and Warnings for Januvia (Sitagliptin)

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  • Januvia (Sitagliptin) can cause a sudden swelling of the pancreas. This can be life-threatening if not treated. Let your doctor know about any stomach pain, nausea, vomiting, or loss of appetite that don't go away.

Means that some groups have a high risk of experiencing this side effect

Tips from pharmacists and people taking Januvia (Sitagliptin)

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The FDA category for this medication is B. It is advised that you: Probably safe
Pregnancy
Weight gain or loss
  • Upsides and downsides from our pharmacists
  • Unlike some diabetes medicines, it's unlikely to cause weight gain and low blood sugar.