Lowers blood sugar.
Our pharmacists’ bottom line
Januvia (Sitagliptin) is a good add-on treatment if your blood sugar is still too high, but you don't want to use an injectable medicine.
- Oral blood sugar-lowering medicine.
- Lowers A1c levels by 0.5-0.8%. (Hemoglobin A1c measures your average blood sugar over time.)
- Prevents the harmful effects of high sugar levels on your organs and blood vessels.
- Uses the hormones naturally produced by your body to affect how sugar is processed.
- Unlike some diabetes medicines, it's unlikely to cause weight gain and low blood sugar.
- You don't have to check your blood sugar every day with this medicine.
- Not as strong as other diabetes medicines. Your doctor might add it to your blood sugar-lowering regimen if your sugar levels are still too high.
- Likely expensive since there's no generic version available.
- Some people might get frequent throat infections or nasal congestion.
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Side effects for Januvia (Sitagliptin)
From clinical trials of Januvia / Type 2 diabetes
- DiarrheaDiarrhea3% for Januvia vs.2% for placebo
- Abdominal painAbdominal pain2% for Januvia vs.2% for placebo
- NauseaNausea1% for Januvia vs.1% for placebo
- Low blood sugarLow blood sugar1% for Januvia vs.1% for placebo
What to expect when you start Januvia (Sitagliptin)Skip what to expect section. Skip to Risks & Warnings section.
- Can cause headache and cold-like symptoms.
- Tell your doctor about persistent stomach pain, nausea, vomiting, or loss of appetite.
- Can be expensive depending on insurance coverage.
- Check your blood sugar regularly.
Risks and Warnings for Januvia (Sitagliptin)Skip Risks and Warnings section. Skip to Tips section.
Januvia (Sitagliptin) can cause a sudden swelling of the pancreas. This can be life-threatening if not treated. Let your doctor know about any stomach pain, nausea, vomiting, or loss of appetite that don't go away.
Tips from pharmacists and people taking Januvia (Sitagliptin)Final section. Do you want to return to drug navigation?
- Upsides and downsides from our pharmacists
- › Unlike some diabetes medicines, it's unlikely to cause weight gain and low blood sugar.