4.3/ 7 average rating with 143 reviewsforJanuvia

Januvia
Alternatives

(sitagliptin)

Januvia (sitagliptin)

Prescription only

Onglyza (saxagliptin)

Prescription only
1 of 7 alternatives
Lowers your blood sugar.

Januvia (sitagliptin) is a good add-on treatment if your blood sugars are not controlled and you don't want to use an injectable medicine.

Lowers blood sugar.

Onglyza (saxagliptin) can cause heart failure unlike other medicines that work just like it.

Upsides
  • Oral blood sugar-lowering medicine.
  • Januvia (sitagliptin) is not linked to worsening heart failure like other medicines in its class.
  • Uses the hormones naturally produced by your body to affect how sugar is processed.
  • It is less likely to cause weight gain and low blood sugar compared to other diabetes medicines.
  • DRUG-NAME is an oral blood sugar lowering medicine. It's a good option if you don't like injections.
  • Does not cause weight gain.
  • May be a good option for those with bad liver function.
  • Does not cause hypoglycemia (low blood sugar) when taken by itself.
Downsides
  • Lowers A1c (average blood sugar over time) by less than 1%.
  • Available as brand version only.
  • Some people might get frequent cold-like symptoms.
  • Rare but serious side effects include pancreatitis and severe joint pain.
  • Typically not first-choice treatment for diabetes.
  • Only lowers A1C (average blood sugar over time) by ~0.5%.
  • Risk for heart failure has not been seen in other medicines that work just like it.
  • May be more expensive than other anti-diabetic medicines.
Used for
Dosage forms
  • Pill
  • Pill
Price
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Reviews
143 
44%
think this treatment is worth it
34%
think this treatment works well
17%
think this treatment is a hassle

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Side effects
3possible side effects
  • Common cold
    5%
  • Diarrhea
    3%
  • Abdominal pain
    2%
See more detailed side effects
The Onglyza (saxagliptin) FDA package insert doesn’t have numbers about how common side effects are.
Risks and warnings
  • Death from inflammation of the pancreas (pancreatitis)

    History of pancreatitis

    ...and 4 more risk factors

  • Kidney damage

    Pre-existing kidney damage

  • Low blood sugar (hypoglycemia)

    Taking medicines for diabetes

See more detailed risks and warnings
  • inflammation of the pancreas

    Alcoholism

    ...and 3 more risk factors

  • Heart failure

    History of heart failure

    ...and 1 more risk factors

  • Low blood sugar (hypoglycemia)

    Alcohol

    ...and 3 more risk factors

See more detailed risks and warnings