Prescription onlyLower-cost generic available



  • Extended release
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Treats ADHD and lowers blood pressure.

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Prescription onlyLower-cost generic available

Our pharmacists’ bottom line

Clonidine is a non-stimulant option to manage ADHD symptoms and behaviors, but it can lower your blood pressure.

  • Can be used alone or together with a stimulant-type medicine to treat ADHD.
  • In studies, it improved attention span and lowered hyperactivity and impulsivity in children and adolescents ages 6 to 17.
  • Also treats blood pressure and some nervous system and psychiatric conditions.
  • Can lower blood pressure.
  • The pill form can make some people sleepy, dizzy, and have dry mouth.
  • You can't miss doses. Stopping Clonidine suddenly can cause your blood pressure to go up suddenly, which raises the risk of heart attack and stroke.

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Side effects for Kapvay (Clonidine)

From clinical trials of Kapvay / ADHD (0.2 mg/day)  ( 152)

  • DrowsinessDrowsiness38% for Clonidine vs.4% for placebo
  • HeadacheHeadache20% for Clonidine vs.16% for placebo
  • FatigueFatigue16% for Clonidine vs.1% for placebo
  • Upper abdominal painUpper abdominal pain15% for Clonidine vs.12% for placebo
  • IrritabilityIrritability9% for Clonidine vs.4% for placebo
  • DizzinessDizziness7% for Clonidine vs.5% for placebo
  • Any side effectAny side effect7% for Clonidine vs.1% for placebo
  • Sleep difficultySleep difficulty5% for Clonidine vs.1% for placebo
  • NightmareNightmare4% for Clonidine vs.0% for placebo
  • NauseaNausea4% for Clonidine vs.3% for placebo

Manufacturers don’t say how common these side effects are

  • Abnormally slow heartbeat
  • Dry mouth
  • Enuresis
  • Increased heart rate
  • Poor quality sleep

What to expect when you take Kapvay (Clonidine)

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Tips from our pharmacists
  • Can cause drowsiness, headache, dizziness, and dry mouth.
  • For ADHD: Might take up to 2 weeks to see effects.
  • For high blood pressure: Check your blood pressure 1 week after starting this medicine, and tell your doctor if it hasn't improved.
  • If side effects don't go away, talk to your doctor about alternatives.
  • Don't stop taking this medicine suddenly.

Risks and Warnings for Kapvay (Clonidine)

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    • Higher risk if:
    • Sudden discontinuation of medicine

    Stopping Kapvay (Clonidine) suddenly can cause agitation, headache, tremors, and a sudden rise of blood pressure that can produce complications. Kapvay (Clonidine) should be stopped over 2-4 days with the supervision of a doctor. If using with a beta blocker medicine, slowly stop the beta blocker first before stopping Kapvay (Clonidine).

Means that some groups have a high risk of experiencing this side effect

Tips from pharmacists and people taking Kapvay (Clonidine)

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The FDA category for this medication is C. It is advised that you: Weigh risks vs. benefits
  • Tips from our pharmacists
  • Can cause drowsiness, headache, dizziness, and dry mouth.
  • Best to take at night due to drowsiness side effect.
    Age: 48
    Gender: Man
    Taken for: ADHD