Prescription onlyLower-cost generic available

Lamictal

(Lamotrigine)

  • Pill
  • Extended release
  • Chewable tablet
  • Dissolving tablet
Back to: Full Site NavigationSkip to: side effects sectionSkip to: What to expect sectionSkip to: Risks and warnings sectionSkip to: Tips from users and pharmacists

Prevents seizures and stabilizes mood.

Skip Upsides & Downsides section. Skip to side effects section.
Prescription onlyLower-cost generic available

Our pharmacists’ bottom line

Lamictal (Lamotrigine) is most useful for treating severe seizure disorders, and for bipolar disorder with more depression symptoms than manic symptoms. Just be careful to increase your dose slowly to avoid skin rash.

Worth it?Is it worth it?
Works well?Does it work?
Hassle?Is it a hassle?
  • Effective at lowering the frequency of seizures in people with epilepsy or Lennox-Gestaut syndrome. Typically used together with other medications for severe seizure disorders.
  • Works best for partial, tonic-clonic, and absence seizures.
  • A first-line treatment for bipolar disorder. Effective long-term treatment for stabilizing mood. Prevents both depressive and manic episodes, but the effect is greater for preventing depression.
  • Doesn't require routine blood tests.
  • Can cause double vision, dizziness, sleepiness, and headache.
  • Has the risk of a rare but life-threatening rash.
  • Can make hormonal birth control less effective.
  • Might be less effective than other medicines for treating manic episodes (acute mania) in people with bipolar disorder.

Save on your next Lamictal (Lamotrigine) prescription

Be sure you’re getting the lowest price for your medication, even if you have insurance.

Skip side effects sections. Skip to What to Expect and Pharmacists Tips section.

Side effects for Lamictal (Lamotrigine)

From clinical trials of Lamictal / Epilepsy, partial seizures ( 43)

  • VomitingVomiting9% for Lamictal vs.0% for placebo
  • IndigestionIndigestion7% for Lamictal vs.0% for placebo
  • NauseaNausea7% for Lamictal vs.0% for placebo
  • Coordination abnormalityCoordination abnormality7% for Lamictal vs.0% for placebo
  • DizzinessDizziness7% for Lamictal vs.0% for placebo
  • Inflammation inside the noseInflammation inside the nose7% for Lamictal vs.0% for placebo
  • Weight decreaseWeight decrease5% for Lamictal vs.0% for placebo
  • Chest painChest pain5% for Lamictal vs.0% for placebo
  • PainPain5% for Lamictal vs.0% for placebo
  • AnxietyAnxiety5% for Lamictal vs.0% for placebo

What to expect when you take Lamictal (Lamotrigine) for Seizures

Skip what to expect section. Skip to Risks & Warnings section.
Tips from our pharmacists
  • Follow dose adjustments set by your doctor to minimize skin rash.
  • Take with food to avoid upset stomach.
  • Report rash, blurry vision, fever, persistent headache, or neck stiffness to your doctor.
  • Makes hormonal birth control less effective.
  • Takes 4 to 6 weeks to feel full effects on mood.

Risks and Warnings for Lamictal (Lamotrigine)

Skip Risks and Warnings section. Skip to Tips section.
    • Higher risk if:
    • History of depression

    Lamictal (Lamotrigine) may increase the risk of suicidal thoughts or behavior. Watch for worsening depression or any unusual changes in mood or behavior, especially during the first few months of treatment or when the dose changes. Report anything concerning to a doctor immediately.

Means that some groups have a high risk of experiencing this side effect

Tips from pharmacists and people taking Lamictal (Lamotrigine)

Final section. Do you want to return to drug navigation?
The FDA category for this medication is C. It is advised that you: Weigh risks vs. benefits
Pregnancy
Food
  • Tips from our pharmacists
  • Take with food to avoid upset stomach.
  • Take it around the same time every day. I have to take mine in the morning and at night. Also taking it with food helps curb nausea & any possible drowsiness.
    Age: 37
    Gender: Woman
    Taken for: Seizures
    Duration taken: Two years or more
Sex
  • supresses libido at 75 mg
    Age: 33
    Gender: Woman
    Taken for: Bipolar II disorder
    Duration taken: A few months
  • Was prescribed lamictal (Off Label) for Bipolar NOS. It's very subtle, but for me it seems to be weight neutral and has no sexual side effects. I still get depressed and (very rarely) manic, but the depressive states are less severe and don't last as long. Inititally, it actually made my mania worse, but that subsided. I should probably give it a higher rating as it does eliminate the mixed states that caused me to have psychotic episodes and two suicide attempts
    Age: 32
    Gender: Woman
    Taken for: Bipolar I disorder (manic)
  • kills sex drive
    Age: 21
    Gender: Woman
    Taken for: Bipolar I disorder (manic)
Sleep
  • Weirdest/best side effect from any medicine goes to Lamictal - for the first couple weeks I had really intense and vivid movie-like dreams. It gives me horrible headaches but I take it before bed so I sleep through it.
    Age: 22
    Gender: Woman
    Taken for: Mood Disorder NOS
    Duration taken: Two years or more
  • Take it around the same time every day. I have to take mine in the morning and at night. Also taking it with food helps curb nausea & any possible drowsiness.
    Age: 37
    Gender: Woman
    Taken for: Seizures
    Duration taken: Two years or more
  • Drink the pill each day on the exact time. Take it 2 hours before bedtime to get you calm to get to sleep and avoid taking a sleeping tablet as well.
    Age: 40
    Gender: Man
    Taken for: Bipolar I disorder (manic)
Weight gain or loss
  • It's not known for weight gain, but coincidentally I have gained weight since taking. I'm not certain if it is due to Lamictal
    Age: 53
    Gender: Woman
    Taken for: Bipolar I disorder (manic)
  • Was prescribed lamictal (Off Label) for Bipolar NOS. It's very subtle, but for me it seems to be weight neutral and has no sexual side effects. I still get depressed and (very rarely) manic, but the depressive states are less severe and don't last as long. Inititally, it actually made my mania worse, but that subsided. I should probably give it a higher rating as it does eliminate the mixed states that caused me to have psychotic episodes and two suicide attempts
    Age: 32
    Gender: Woman
    Taken for: Bipolar I disorder (manic)
  • Haven't started taking it. Due to insurance companies refusing to cover Latuda, starting 1/1/2017, I'll need to switch. Liking into Lamictal ... any thoughts would be welcome. I'm afraid of weight gain. Had anyone experienced significant weight gain?
    Age: 57
    Gender: Woman
    Taken for: Seizures