Prescription onlyLower-cost generic availableClass: Cardiovascular

Lasix Alternatives

(furosemide)

Prescription onlyLower-cost generic availableClass: Cardiovascular
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Compare Lasix (furosemide) to alternatives

These medications are comparable to Lasix (furosemide) or used for similar purposes.

Lasix
(furosemide)

Microzide
(hydrochlorothiazide )

Zestril
(lisinopril)

Aldactone
(spironolactone)

Edecrin
(ethacrynic acid)

Lanoxin
(digoxin)

Lowers blood pressure. Removes extra water from your body. Lasix (Furosemide) is a very effective water pill and it'll certainly make you go to the bathroom more often.Removes water from the body, which lowers blood pressure. Microzide (hydrochlorothiazide (HCTZ)) is a well-tolerated water pill that's often the first-choice treatment for mild high blood pressure.Lowers blood pressure. Zestril (lisinopril) is a good blood pressure-lowering medicine that protects kidney function.Removes extra water from your body. Aldactone (spironolactone) should be used with other medicines to get rid of excess fluid in your body, especially if you have heart failure.Coming soon.Improves heart pumping. Digoxin is a good backup for treating heart failure symptoms, but it doesn't, by itself, lower your risk of death.
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Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
5.06Lasix
Reviews for Lasix
67%
of people (All ages) say Lasix is worth it
47%
say it works well
16%
say it's a big hassle
371 reviews
Have you used Lasix (furosemide)?
Worth itNot sureNot worth it
Reviews for hydrochlorothiazide
47%
+20% better vs. Lasix
31%
+16% better vs. Lasix
16%
Same vs. Lasix
139 reviews
Have you used Microzide (hydrochlorothiazide )?
Worth itNot sureNot worth it
Reviews for Lisinopril
61%
+6% better vs. Lasix
51%
-4% worse vs. Lasix
14%
-2% worse vs. Lasix
687 reviews
Have you used Zestril (lisinopril)?
Worth itNot sureNot worth it

Not enough reviews for this treatment. Help someone out, leave a review!

Have you used Aldactone (spironolactone)?
Worth itNot sureNot worth it

Not enough reviews for this treatment. Help someone out, leave a review!

Have you used Edecrin (ethacrynic acid)?
Worth itNot sureNot worth it
Reviews for Digoxin
64%
+3% better vs. Lasix
43%
+4% better vs. Lasix
31%
+15% better vs. Lasix
Have you used Lanoxin (digoxin)?
Worth itNot sureNot worth it
Side effects
LasixhydrochlorothiazideLisinoprilspironolactoneEdecrinDigoxin

The Lasix FDA package insert doesn’t have numbers about how common side effects are.

More about Lasix side effects »

The hydrochlorothiazide FDA package insert doesn’t have numbers about how common side effects are.

More about hydrochlorothiazide side effects »
  • Headache 4%
  • Dizziness 4%
  • Cough 3%
  • Low blood pressure 4%
  • Chest pain 2%
  • Kidney damage 10%
  • Fainting 7%
  • High potassium 6%
More Lisinopril side effects »

The spironolactone FDA package insert doesn’t have numbers about how common side effects are.

More about spironolactone side effects »

We haven’t found good data for Edecrin side effects.

FDA side effect reports for Edecrin »
  • Any side effect 20%
  • Dizziness 1%
  • Mental disturbances 4%
  • Nausea 1%
  • Diarrhea 3%
  • Death 1%
  • Side effects requiring hospitalization 1%
  • Abnormally fast heart beat 2%
  • Vomiting 2%
More Digoxin side effects »
How it works
LasixhydrochlorothiazideLisinoprilspironolactoneEdecrinDigoxin
Lasix (Furosemide) is a loop diuretic (water pill). It works in the kidneys to make you urinate more, which removes extra water and certain electrolytes. This lowers blood pressure and swelling.Microzide (hydrochlorothiazide (HCTZ)) is a thiazide diuretic (water pill) that makes you urinate more. It works in the kidneys to remove extra water and certain electrolytes, while lowering blood pressure and reducing swelling.Zestril (lisinopril) is an angiotensin converting enzyme (ACE) inhibitor. It blocks a chemical that tightens blood vessels. This makes blood vessels relax, which lowers blood pressure and allows more blood and oxygen to get to your heart and other organs.Aldactone (spironolactone) is a potassium-sparing diuretic that blocks aldosterone (a hormone) and helps the kidney get rid of excess fluids in your body.Coming soon.Digoxin helps your heart work more efficiently. It makes your heart pump slower and stronger, which helps it get more blood and oxygen out to your body and organs.
Type of medication
LasixhydrochlorothiazideLisinoprilspironolactoneEdecrinDigoxin
Prescription onlyPrescription onlyPrescription onlyPrescription onlyPrescription only
Available as
LasixhydrochlorothiazideLisinoprilspironolactoneEdecrinDigoxin
  • Pill
  • Liquid
  • Pill
  • Pill
  • Liquid
  • Pill
  • Pill
  • Pill
  • Liquid
Used for
LasixhydrochlorothiazideLisinoprilspironolactoneEdecrinDigoxin
  • Edema
Risk factors for serious side effects
LasixhydrochlorothiazideLisinoprilspironolactoneEdecrinDigoxin
  • Current electrolyte imbalance
  • History of sulfa allergies
  • Current kidney problems
  • Dose too high
  • Low blood protein
Detailed Lasix (furosemide) risks & warnings »
  • Current electrolyte imbalance
  • Lower kidney function
  • Dehydration
  • History of sulfa allergies
  • History of gout
Detailed Microzide (hydrochlorothiazide ) risks & warnings »
  • Women of childbearing age
  • African descent
  • Current kidney problems
  • Medicines that increase potassium
  • Use of salt substitutes
Detailed Zestril (lisinopril) risks & warnings »
  • Taking with alcohol
  • Taking other medicines that lower your blood pressure
  • Current kidney problems
  • Taking other medicines that increase potassium
  • Use of salt substitutes
Detailed Aldactone (spironolactone) risks & warnings »
    Coming soon.
    • History of heart problems
    • Drug interactions
    • Wolff-Parkinson-White syndrome
    • Low body weight, advanced age, impaired renal function, electrolyte imbalances
    • Overactive or underactive thyroid
    Detailed Lanoxin (digoxin) risks & warnings »
    Pregnancy

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

    Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    Interactions
    LasixhydrochlorothiazideLisinoprilspironolactoneEdecrinDigoxin
    No interactions related info.No interactions related info.No interactions related info.No interactions related info.No interactions related info.
    • Tell your doctor about other medicines you're taking to avoid drug interactions.
    Kidneys and liver
    LasixhydrochlorothiazideLisinoprilspironolactoneEdecrinDigoxin
    • Requires routine blood tests to check kidney function.
    • Requires routine blood tests to check kidney function.
    • You'll need to have blood tests done to check your kidney function.
    • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
    • You'll need to have blood tests done regularly since Aldactone (spironolactone) can affect your potassium levels and kidneys.
    No kidneys and liver related info.No kidneys and liver related info.
    Pain
    LasixhydrochlorothiazideLisinoprilspironolactoneEdecrinDigoxin
    No pain related info.No pain related info.No pain related info.
    • It can cause breast pain/swelling, irregular periods (women), or trouble with sexual performance.
    No pain related info.No pain related info.
    Upsides and benefits
    LasixhydrochlorothiazideLisinoprilspironolactoneEdecrinDigoxin
    • A strong diuretic (water pill) that works well to get rid of extra fluids in your body through urination.
    • Lowers your blood pressure and your risk of heart attack and stroke.
    • Works better than thiazide diuretics (like Hydrochlorothiazide) at removing harmful levels of certain electrolytes, such as potassium.
    • Okay to take if you have kidney problems.
    • Does a good job getting rid of extra fluids in your body by making you urinate more.
    • A first-choice blood pressure treatment. Works especially well for people of African descent.
    • Lowers the risk of heart attack and stroke.
    • Good option if you have high blood pressure and heart failure.
    • Most people have very few side effects from Microzide (hydrochlorothiazide (HCTZ)).
    • Can be good for patients with osteoporosis since it raises the body's level of calcium.
    • A first-choice blood pressure treatment for many people.
    • Lowers the risk of heart attack and stroke.
    • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
    • Recommended for anyone with heart failure since it lowers the risk of death and further damage to your heart.
    • Very cheap drug, and comes available as a liquid for children over 6 years of age.
    • Has a low risk of causing muscle problems from low potassium levels in your blood.
    • More useful when taken with another diuretic that'll also help your body get rid of extra fluids.
    • Can lower blood pressure.
    • Reduces the risk of death in people with heart failure.
    Coming soon
    • Used for some abnormal heart rhythms, and for heart failure that can't be controlled by other medications.
    • Relieves shortness of breath, and makes it easier to be active without having symptoms.
    • In studies, Digoxin lowered the risk of having to be admitted to the hospital for worsening heart failure.
    Downsides and risks
    LasixhydrochlorothiazideLisinoprilspironolactoneEdecrinDigoxin
    • Makes you urinate very frequently.
    • Can cause low levels of important electrolytes, such as potassium.
    • Makes you urinate more often.
    • Microzide (hydrochlorothiazide (HCTZ)) doesn't work well in people with severe kidney problems.
    • It can increase the risk of gout attacks in people with poor kidney function or a history of gout.
    • People with a sulfa allergy may be allergic to Microzide (hydrochlorothiazide (HCTZ)).
    • Up to 10% of people can get a dry cough while using this medicine. It ranges from a mild tickle in the throat to a persistent hacking cough.
    • Requires a yearly blood test to see how the medicine is affecting your body.
    • Zestril (lisinopril) isn't safe to use if you're pregnant.
    • Doesn't work as well in people of African descent, and can cause a greater chance of face, tongue, or lip swelling.
    • Aldactone (spironolactone) doesn't work well on its own. It should be used with another drug to help get rid of excess fluids.
    • Has many possible side effects, especially when higher doses are used.
    • Can increase the risk of tumor growth.
    • You'll need to have blood tests done regularly since Aldactone (spironolactone) can affect your potassium levels and kidneys.
    Coming soon
    • For heart failure, relieves symptoms, but does not lower the risk of death. That's why it's usually used together with other heart failure medicines that do lower the risk of death.
    • Requires blood tests, especially during the first few weeks of treatment.
    Tips from our pharmacists for people taking the medication
    LasixhydrochlorothiazideLisinoprilspironolactoneEdecrinDigoxin
    • Starts working in 30 minutes.
    • Makes you urinate more often, so avoid taking it at bedtime.
    • Can cause dizziness in the first few days.
    • Check your blood pressure 1 week after starting this medicine, and tell your doctor if it hasn't improved.
    • Tell your doctor about any dizziness, fatigue, or muscle weakness that doesn't go away.
    • Requires routine blood tests to check kidney function.
    • Microzide (hydrochlorothiazide (HCTZ)) starts working in about 2 hours.
    • It makes you urinate more often, so don't take it at bedtime.
    • Can cause dizziness in the first few days.
    • Check your blood pressure 1 week after starting this medicine, and tell your doctor if it hasn't improved.
    • Tell your doctor about any tiredness or muscle weakness that doesn't go away.
    • Requires routine blood tests to check kidney function.
    • Can cause dizziness the first few days you're taking it.
    • Check your blood pressure about 1 week after starting Zestril (lisinopril), and tell your doctor if it hasn't improved.
    • Let your doctor know about any dizziness, tiredness, cough, or throat irritation that doesn't go away.
    • You'll need to have blood tests done to check your kidney function.
    • Don't take Zestril (lisinopril) if you're pregnant.
    • Can make you dizzy or cause trouble concentrating, so be careful using it until you know how the medicine affects you.
    • Don't use supplements or salt substitutes that are high in potassium.
    • It can cause breast pain/swelling, irregular periods (women), or trouble with sexual performance.
    • Tell your doctor about any muscle weakness, skin changes, and red or black tarry stool.
    • You will urinate more often within 2 to 3 days, and will have lower blood pressure in 2 to 3 weeks.
    Coming soon
    • Take it at the same time every day.
    • Drink plenty of water while taking this medicine.
    • Requires routine blood tests to make sure you have the right amount of Digoxin in your body.
    • Tell your doctor about other medicines you're taking to avoid drug interactions.
    Learn more
    More about LasixSide effectsReviews & ratingsAlternativesFDA package insert
    Have you used Lasix (furosemide)?
    Worth itNot sureNot worth it
    More about hydrochlorothiazideSide effectsReviews & ratingsFDA package insert
    Have you used Microzide (hydrochlorothiazide )?
    Worth itNot sureNot worth it
    More about LisinoprilSide effectsReviews & ratingsFDA package insert
    Have you used Zestril (lisinopril)?
    Worth itNot sureNot worth it
    More about spironolactoneSide effectsFDA package insert
    Have you used Aldactone (spironolactone)?
    Worth itNot sureNot worth it
    More about EdecrinSide effectsFDA package insert
    Have you used Edecrin (ethacrynic acid)?
    Worth itNot sureNot worth it
    More about DigoxinSide effectsReviews & ratingsFDA package insert
    Have you used Lanoxin (digoxin)?
    Worth itNot sureNot worth it