Prescription onlyLower-cost generic available

Zestril

(Lisinopril)

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Lowers blood pressure.

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Prescription onlyLower-cost generic available

Our pharmacists’ bottom line

Zestril (Lisinopril) is a good blood pressure-lowering medicine that protects kidney function.

Worth it?Is it worth it?
Works well?Does it work?
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  • A first-choice blood pressure treatment for many people.
  • Lowers the risk of heart attack and stroke.
  • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
  • Recommended for anyone with heart failure since it lowers the risk of death and further damage to your heart.
  • Up to 1 in 10 people can get a dry cough with this medicine. It ranges from a mild tickle in the throat to a persistent hacking cough.
  • Requires a yearly blood test to see how the medicine is affecting your body.
  • Not safe to use if you're pregnant.

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Side effects for Zestril (Lisinopril)

From clinical trials of Lisinopril / High blood pressure ( 1556)

  • HeadacheHeadache6% for Lisinopril vs.2% for placebo
  • DizzinessDizziness5% for Lisinopril vs.2% for placebo
  • CoughCough4% for Lisinopril vs.1% for placebo
  • DiarrheaDiarrhea3% for Lisinopril vs.2% for placebo
  • FatigueFatigue3% for Lisinopril vs.1% for placebo
  • InfectionInfection2% for Lisinopril vs.0% for placebo
  • NauseaNausea2% for Lisinopril vs.2% for placebo
  • Low blood pressureLow blood pressure1% for Lisinopril vs.0% for placebo
  • ImpotenceImpotence1% for Lisinopril vs.0% for placebo
  • Muscle weaknessMuscle weakness1% for Lisinopril vs.1% for placebo

What to expect when you take Zestril (Lisinopril) for Lowers blood pressure

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Tips from our pharmacists
  • Can cause dizziness in the first few days.
  • Check your blood pressure 1 week after starting this medicine, and tell your doctor if it hasn't improved.
  • Tell your doctor about any dizziness, fatigue, cough, or throat irritation that doesn't go away.
  • Requires routine blood tests to check kidney function.
  • Don't take it if you're pregnant.

Risks and Warnings for Zestril (Lisinopril)

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    • Higher risk if:
    • Women of childbearing age

    Zestril (Lisinopril) can cause birth defects or death to a fetus. If you are pregnant or considering having a baby, talk to your doctor about alternative medicines.

    This is a black box warning. The FDA requires this warning when there is a significant risk of serious or life-threatening effects that anyone taking the drug should consider.

Means that some groups have a high risk of experiencing this side effect

Tips from pharmacists and people taking Zestril (Lisinopril)

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The FDA category for this medication is D. It is advised that you: Weigh risks vs. benefits
Pregnancy
Kidneys & liver
  • Upsides and downsides from our pharmacists
  • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
  • Tips from our pharmacists
  • Requires routine blood tests to check kidney function.
  • It will make you sleepy!I took a very low dose, 2.5 mg., to protect my kidney function from lupus. I had to get off it due to a life-threatening, but comical, allergic reaction: angio-edema causing facial swelling.
    Age: 47
    Gender: Woman
    Taken for: High blood pressure