Prescription onlyLower-cost generic available

Zestril

(Lisinopril)

Prescription onlyLower-cost generic available
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Lowers blood pressure.

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Our bottom line

Zestril (Lisinopril) is a good blood pressure-lowering medicine that protects kidney function.

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Upsides

  • A first-choice blood pressure treatment for many people.
  • Lowers the risk of heart attack and stroke.
  • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
  • Recommended for anyone with heart failure since it lowers the risk of death and further damage to your heart.
People say this drug is:
676 reviews

Downsides

  • Up to 1 in 10 people can get a dry cough with this medicine. It ranges from a mild tickle in the throat to a persistent hacking cough.
  • Requires a yearly blood test to see how the medicine is affecting your body.
  • Not safe to use if you're pregnant.

What to expect when you take Zestril (Lisinopril) for Lowers blood pressure

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Side effect rates for Zestril (Lisinopril)

From clinical trials of Lisinopril / After heart attack
  • Low blood pressure
  • Renal dysfunction

Risks and Warnings for Zestril (Lisinopril)

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    • Higher risk if:
    • Women of childbearing age

    Zestril (Lisinopril) can cause birth defects or death to a fetus. If you are pregnant or considering having a baby, talk to your doctor about alternative medicines.

    This is a black box warning. The FDA requires this warning when there is a significant risk of serious or life-threatening effects that anyone taking the drug should consider.

Means that some groups have a high risk of experiencing this side effect

Common concerns from people taking Zestril (Lisinopril)

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Pregnancy
Kidneys and liver
  • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
  • Requires routine blood tests to check kidney function.
Pain
  • Had severe muscle pain (enough to make walking/biking almost impossible) at the 20mg dose, had to go down to 10mg dose.
Sleep
  • It will make you sleepy!I took a very low dose, 2.5 mg., to protect my kidney function from lupus. I had to get off it due to a life-threatening, but comical, allergic reaction: angio-edema causing facial swelling.