Prescription onlyLower-cost generic available

Lotrel

(Amlodipine / Benazepril)

Prescription onlyLower-cost generic available
  • Pill
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Lowers blood pressure.

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Our bottom line

Lotrel (Amlodipine / Benazepril) is good because it combines two first-line medications to lower blood pressure, and it's available in generic. However, it can cause throat irritation or a dry cough, and you can't stop it suddenly since it can cause your blood pressure to rise.

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Upsides

  • Both medications in Lotrel (Amlodipine / Benazepril) are recommended as first line medications to help lower blood pressure.
  • The combination of these two medications work together to lower your blood pressure better than either by itself.
  • This combines two medications into one pill, so it reduces the amount of pills you have to take every day.
  • Available as a generic version, so it shouldn't be too expensive.

Downsides

  • Can't be stopped suddenly because it can cause your blood pressure to bounce back very high.
  • Because it comes in fixed doses, it's hard to switch dosages if one medication isn't working as well as the other.
  • If you're pregnant or want to be pregnant, you'll have to be changed to another medication since Lotrel (Amlodipine / Benazepril) can cause birth defects.
  • In some people, benazepril, the ACE inhibitor, can cause throat irritation or a dry cough, and you can switch to another medication if it bothers you.
  • This is usually not given until you've tried at least one medication to lower your blood pressure and it hasn't worked.
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Side effect rates for Lotrel (Amlodipine / Benazepril)

1170 From clinical trials of Lotrel / High blood pressure
  • Any side effect
  • Cough
  • Headache
  • Swelling due to excess fluid

Risks and Warnings for Lotrel (Amlodipine / Benazepril)

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    • Higher risk if:
    • Women of childbearing age

    Lotrel (Amlodipine / Benazepril) can cause birth defects. If you're pregnant or considering having a baby, talk to your doctor about alternative medicines.

    This is a black box warning. The FDA requires this warning when there is a significant risk of serious or life-threatening effects that anyone taking the drug should consider.

Means that some groups have a high risk of experiencing this side effect

Common concerns from people taking Lotrel (Amlodipine / Benazepril)

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Pregnancy