Prescription onlyLower-cost generic availableClass: Neuro/psych



Prescription onlyLower-cost generic availableClass: Neuro/psych
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Treats schizophrenia.

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Our bottom line

Loxitane (loxapine) is not recommended as a first choice medicine for treatment of schizophrenia, but it can be good if other medicines haven't worked because of bad side effects.


  • Loxitane (loxapine) can be used to control schizophrenia if other medicines haven't worked because you don't like their side effects.
  • Loxitane (loxapine) is available as a generic.


  • Loxitane (loxapine) is not recommended as a first choice for treating schizophrenia because it's more likely to cause trouble with controlling movements.
  • Loxitane (loxapine) can stop vomiting, so it can be difficult to tell if someone's overdosed on drugs.
  • Loxitane (loxapine) can raise heart rate and lower blood pressure.
How it works

Loxitane (loxapine) is a typical antipsychotic. It works in the brain to calm down parts of the brain that might be responsible for aggressive behavior.

What to expect when you take Loxitane (loxapine) for Schizophrenia

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Side effect rates for Loxitane (loxapine)

Risks and Warnings for Loxitane (loxapine)

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    • Higher risk if:
    • People age 65 and older with dementia and psychosis

    Older people who have dementia and psychosis have a higher risk of death if they take antipsychotic medicines like Loxitane (loxapine). They shouldn't be given this medicine.

    This is a black box warning. The FDA requires this warning when there is a significant risk of serious or life-threatening effects that anyone taking the drug should consider.

Means that some groups have a high risk of experiencing this side effect

Common concerns from people taking Loxitane (loxapine)

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  • Don't drink alcohol or take narcotics while taking Loxitane (loxapine) since you can have problems breathing.
  • Take Loxitane (loxapine) with food to avoid stomach upset.