Prescription onlyNo lower cost generic available

Lyrica

(Pregabalin)

Prescription onlyNo lower cost generic available
Back to: Full Site NavigationSkip to: side effects sectionSkip to: What to expect sectionSkip to: Risks and warnings sectionSkip to: Common concerns from users and pharmacists

Treats nerve pain and prevents seizures.

Skip Upsides & Downsides section. Skip to side effects section.

Our bottom line

Lyrica (Pregabalin) works well as an add-on medicine for seizures and fibromyalgia, but it's especially effective for nerve-related pain after shingles. Not available as a generic, so it might be expensive.

Coupons and discounts

Upsides

  • Relieves nerve-related (neuropathic) pain caused by different conditions including diabetes, shingles (herpes zoster), fibromyalgia, and spinal cord damage.
  • Studies show that lower doses of Lyrica (Pregabalin) cause fewer side effects and still relieve pain just as well as higher doses.
  • Also used in combination with other medications to treat epilepsy (partial seizures).
People say this drug is:
63 reviews

Downsides

  • Not available as a generic, so it can be pricey.
  • You can't skip or miss doses since suddenly stopping Lyrica (Pregabalin) can cause seizures.
  • Lyrica (Pregabalin) is likely to cause some side effects, including memory problems, drowsiness, dizziness, and confusion.
  • Has a higher risk than other pain medicines of affecting your heart rate or rhythm, so it might not be the best choice if you have cardiovascular disease (previous heart attack, stroke, fast/uncontrolled heart rate, or irregular heartbeat).

What to expect when you take Lyrica (Pregabalin) for Diabetic nerve pain

Skip what to expect section. Skip to Risks & Warnings section.
Skip side effects section. Skip to What to Expect and Pharmacists Tips section.

Side effect rates for Lyrica (Pregabalin)

637 From clinical trials of Lyrica / Fibromyalgia (150 mg daily)
  • Dizziness
  • Drowsiness
  • Headache
  • Weight increased
  • Vision blurred
  • Dry mouth
  • Ankle and leg swelling
  • Fatigue
  • Sinus inflammation
  • Joint pain

Risks and Warnings for Lyrica (Pregabalin)

Skip risks section. Skip to common concerns section.
  • Lyrica (Pregabalin) is only approved for use in adults. It can increase the risk of suicidal thoughts or behavior. Report new or worsening depression or unusual changes in mood or behavior to your doctor right away, especially during the first few months of treatment or when the dose changes.

Common concerns from people taking Lyrica (Pregabalin)

Final section. Do you want to return to drug navigation?
Pregnancy
Alcohol
  • It's not safe to take this medication with alcohol or other drugs that make you drowsy.
  • It enhances the effects of other drugs, so avoid alcohol at all costs. Causes sleepiness so take it at night. Taking it for Generalised Anxiety Disorder, and I can't say it has helped greatly.
Food
  • Hide all food in the house, or you will eat it all in one day.
  • Start slowly and work your way up. Even experiment taking it with or without food to get rid of the initial side effects.
Pain
  • Has a higher risk than other pain medicines of affecting your heart rate or rhythm, so it might not be the best choice if you have cardiovascular disease (previous heart attack, stroke, fast/uncontrolled heart rate, or irregular heartbeat).
  • I did find it took my body a bit to get used to the drug, I did have some dizziness. The pain relief was worth every penny. It's the best I have felt in years!
  • Worked well for the pain that I had in my kidney due to kidney stones. haven't experienced much side effects, haven't gained weight neither. Good medication for nerve pain.
  • Works better if taken before pain starts. Also, sometimes it makes it hard to concentrate.
Sleep
  • Lyrica (Pregabalin) is likely to cause some side effects, including memory problems, drowsiness, dizziness, and confusion.
  • Can make you drowsy or dizzy.
  • Take it at night, it will help you sleep better without the pain
  • I've been on Lyrica for many years now. It has never helped my Fibromyalgia! All it does is cause drowsiness, so I only take 100mg before bedtime.
  • Don't take it if you are prone to sleepiness while driving especially combined with Cymbalta and/or Ropinorole
Weight
  • unhappy about Weight gain
  • This stuff is notorious for making people gain weight!! I was on it for about 4 months and it made me gain more than 30lbs....
  • Great if you're thin, but if on the heavy side ask for something different as this medication will put weight on you, don't stop it suddenly as the withdrawals are horrendous, go to your gp or neurologist to set out a plan to be weaned off