Lyrica

(Pregabalin)

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4.39Lyrica

Treats nerve pain and prevents seizures.

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Our bottom line

Lyrica (Pregabalin) works well as an add-on medicine for seizures and fibromyalgia, but it's especially effective for nerve-related pain after shingles. Not available as a generic, so it might be expensive.

Quick facts about Lyrica
  • Drug class: Neurology
  • Rx status: Prescription only
  • Generic status: No lower cost generic available
Prices and discounts
Lowest price for 60 75mg capsules
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$431.10
  • Retail price
    507.18
  • Savings
    15%

Upsides

  • Relieves nerve-related (neuropathic) pain caused by different conditions including diabetes, shingles (herpes zoster), fibromyalgia, and spinal cord damage.
  • Studies show that lower doses of Lyrica (Pregabalin) cause fewer side effects and still relieve pain just as well as higher doses.
  • Also used in combination with other medications to treat epilepsy (partial seizures).
People’s experience with Lyrica

66reviews so far. What do you think?

Worth itNot sureNot worth it

Downsides

  • Not available as a generic, so it can be pricey.
  • You can't skip or miss doses since suddenly stopping Lyrica (Pregabalin) can cause seizures.
  • Lyrica (Pregabalin) is likely to cause some side effects, including memory problems, drowsiness, dizziness, and confusion.
  • Has a higher risk than other pain medicines of affecting your heart rate or rhythm, so it might not be the best choice if you have cardiovascular disease (previous heart attack, stroke, fast/uncontrolled heart rate, or irregular heartbeat).
Prices and discounts
Lowest price for 60 75mg capsules
Determining your location...
$431.10
  • Retail price
    507.18
  • Savings
    15%
How it works

Lyrica (Pregabalin) is a nerve pain reliever. Researchers don't know exactly how it works, but it has a similar structure to GABA, a neurotransmitter that calms nerves in the brain and spinal cord.

Quick facts about Lyrica
  • Drug class: Neurology
  • Rx status: Prescription only
  • Generic status: No lower cost generic available

Dosage forms

  • Pill
  • Liquid
People’s experience with Lyrica

66reviews so far. What do you think?

Worth itNot sureNot worth it

What to expect when you take Lyrica (Pregabalin) for Diabetic nerve pain

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Side effect rates for Lyrica (Pregabalin)

637 From clinical trials of Lyrica / Fibromyalgia (150 mg daily)
  • Vertigo
  • Vomiting
  • Abdominal distension
  • Chest pain
  • Fluid retention
  • Muscle spasms
  • Back pain
  • Balance disorder
  • Coordination abnormal
  • Hypoesthesia

Risks and Warnings for Lyrica (Pregabalin)

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  • Lyrica (Pregabalin) is only approved for use in adults. It can increase the risk of suicidal thoughts or behavior. Report new or worsening depression or unusual changes in mood or behavior to your doctor right away, especially during the first few months of treatment or when the dose changes.

Common concerns from people taking Lyrica (Pregabalin)

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Pregnancy
Price
  • Not available as a generic, so it can be pricey.
  • Cost vs sideeffects. Worried to try to switch and my pain gets out of control
Alcohol
  • It's not safe to take this medication with alcohol or other drugs that make you drowsy.
Food
  • Start slowly and work your way up. Even experiment taking it with or without food to get rid of the initial side effects.
  • Hide all food in the house, or you will eat it all in one day.
Pain
  • Has a higher risk than other pain medicines of affecting your heart rate or rhythm, so it might not be the best choice if you have cardiovascular disease (previous heart attack, stroke, fast/uncontrolled heart rate, or irregular heartbeat).
  • Worked well for the pain that I had in my kidney due to kidney stones. haven't experienced much side effects, haven't gained weight neither. Good medication for nerve pain.
Sleep
  • Can make you drowsy or dizzy.
  • Lyrica (Pregabalin) is likely to cause some side effects, including memory problems, drowsiness, dizziness, and confusion.
  • I've been on Lyrica for many years now. It has never helped my Fibromyalgia! All it does is cause drowsiness, so I only take 100mg before bedtime.
  • It does cause a lot of drowsiness at first, but there is adjustment to that. 2-3 hours after taking it there is drowsiness. I only take it in evening due to that.
Weight
  • Up to 200mg 3 times a day. Fatigued, unstable gait, lack of concentration, much weight gain. Also take Cymbalta, Celebrex, and Elavil. Beginning to think my doctors don't care OR don't know what is right for me!
  • Great if you're thin, but if on the heavy side ask for something different as this medication will put weight on you, don't stop it suddenly as the withdrawals are horrendous, go to your gp or neurologist to set out a plan to be weaned off
  • This stuff is notorious for making people gain weight!! I was on it for about 4 months and it made me gain more than 30lbs....