Lyrica

(pregabalin)

3.3/ 5 average rating with 66 reviewsforLyrica
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Treats pain caused by nerve damage and prevents seizures.

Skip Upsides & Downsides section. Skip to side effects section.

Our bottom line

Lyrica (pregabalin) is first-choice treatment for nerve pain, but may be expensive since it is available as brand name only.

Quick facts about Lyrica
  • Drug class: Neurology
  • Rx status: Prescription only
  • Generic status: No lower cost generic available
Prices and discounts
Lowest price for 60 75mg capsules
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$432.74
  • Retail price
    $534.64
  • Savings
    19%

Upsides

  • Unlike other pain relievers, it is very effective at treating and preventing nerve damage caused by diabetes, shingles, fibromyalgial, and spinal cord injuries.
  • It is less habit forming than narcotics.
  • It can also be used in combination with other anti-seizure medicines to treat epilepsy.

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What to expect from Lyrica, on one page

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People’s experience with Lyrica

66reviews so far. What do you think?

Downsides

  • Likely expensive since it is not available in generic versions.
  • Has a higher risk than other pain medicines to affect your heart rate or rhythm.
  • Requires adjustment in dose if you have lower kidney function.
  • Higher doses can cause drowsiness so you will have to divide the dose and take it throughout the day.

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Sign up and get Pill Talk, the latest in health & medicine news from Iodine

Get our free fact sheet

What to expect from Lyrica, on one page

Download Fact Sheet
Prices and discounts
Lowest price for 60 75mg capsules
Determining your location...
$432.74
  • Retail price
    $534.64
  • Savings
    19%
How it works

Lyrica (pregabalin) is a gamma-aminobutyric acid (GABA) analog, which decreases activity at the nerve endings to relieve pain and prevent seizures.

Quick facts about Lyrica
  • Drug class: Neurology
  • Rx status: Prescription only
  • Generic status: No lower cost generic available

Used for

Dosage forms

  • Pill
  • Liquid
People’s experience with Lyrica

66reviews so far. What do you think?

What to expect when you take Lyrica (pregabalin) for Fibromyalgia

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Skip side effects section. Skip to risks and warnings section.

Side effect rates for Lyrica (pregabalin)

From 637 clinical trials of Lyrica when taken for fibromyalgia (150 mg daily)
  • Dizziness
  • Drowsiness
  • Headache
  • Blurry vision
  • Weight gain
  • Dry mouth
  • Fatigue
  • Swelling of the hands and feet
  • Constipation
  • Sinus infection

Risks and Warnings for Lyrica (pregabalin)

Skip risks section. Skip to common concerns section.
    • Higher risk if:
    • Starting Lyrica (pregabalin) or changing doses

    Lyrica (pregabalin) can increase the risk of suicidal thoughts or behavior. Report new or worsening symptoms of depression or unusual changes in mood or behavior to your doctor right away.

Common concerns from people taking Lyrica (pregabalin)

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Price
  • Reviewed Lyricaon 7/18/2017Cost vs sideeffects. Worried to try to switch and my pain gets out of control
    44
    Woman
    Two years or more
    Fibromyalgia
Food
  • Reviewed Lyricaon 7/13/2016Start slowly and work your way up. Even experiment taking it with or without food to get rid of the initial side effects.
    45
    Woman
    Nerve pain from diabetes
  • Reviewed Lyricaon 1/30/2017Hide all food in the house, or you will eat it all in one day.
    54
    Man
    Nerve pain from shingles
Kidneys and liver
  • Requires adjustment in dose if you have lower kidney function.
Pain
  • Unlike other pain relievers, it is very effective at treating and preventing nerve damage caused by diabetes, shingles, fibromyalgial, and spinal cord injuries.
  • Has a higher risk than other pain medicines to affect your heart rate or rhythm.
  • Reviewed Lyricaon 1/29/2017Worked well for the pain that I had in my kidney due to kidney stones. haven't experienced much side effects, haven't gained weight neither. Good medication for nerve pain.
    31
    Man
    Fibromyalgia
  • Reviewed Lyricaon 9/17/2017Wish I could have been told my pain wouldn't be any better, and, how about making it a lot more affordable for us. In my generation, the majority of us can't afford to pay for it and still meet our other needs.
    70
    Man
    Two years or more
    Nerve pain
Sleep
  • Lyrica (pregabalin) causes drowsiness. Avoid activities that require you to be alert, such as driving a car or operating machinery, until you know how this medicine affects you.
  • Higher doses can cause drowsiness so you will have to divide the dose and take it throughout the day.
  • Reviewed Lyricaon 4/8/2017It does cause a lot of drowsiness at first, but there is adjustment to that. 2-3 hours after taking it there is drowsiness. I only take it in evening due to that.
    61
    Woman
    Two years or more
    Fibromyalgia
  • Reviewed Lyricaon 3/16/2017I've been on Lyrica for many years now. It has never helped my Fibromyalgia! All it does is cause drowsiness, so I only take 100mg before bedtime.
    51
    Woman
    Two years or more
    Fibromyalgia
  • Reviewed Lyricaon 10/8/2017I’m still on it, titrating up. The jury is still out on this. The drowsiness it causes affects my life in a major way every time pain management makes an increase and I have to ride it out until my system adjusts to it. Came down with constipation a week after titrating up to 150 mg a day. I keep having back pain flares and my physical therapy is not keeping those at bay, hence the dosage increases. I will say that this drug is more tolerable for me than Gabapentin.
    36
    Woman
    A few months
    Nerve pain
Weight
  • Reviewed Lyricaon 6/13/2015Up to 200mg 3 times a day. Fatigued, unstable gait, lack of concentration, much weight gain. Also take Cymbalta, Celebrex, and Elavil. Beginning to think my doctors don't care OR don't know what is right for me!
    59
    Man
    A year or so
    Nerve pain from spinal cord injury
  • Reviewed Lyricaon 7/2/2016Great if you're thin, but if on the heavy side ask for something different as this medication will put weight on you, don't stop it suddenly as the withdrawals are horrendous, go to your gp or neurologist to set out a plan to be weaned off
    45
    Woman
    Nerve pain from spinal cord injury
  • Reviewed Lyricaon 7/28/2016This stuff is notorious for making people gain weight!! I was on it for about 4 months and it made me gain more than 30lbs....
    44
    Man
    Nerve pain from spinal cord injury