Prescription onlyLower-cost generic available

Maxalt Alternatives

(Rizatriptan)

  • Pill
  • Dissolving tablet
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Compare Maxalt (Rizatriptan) to alternatives

These medications are comparable to Maxalt (Rizatriptan) or used for similar purposes.

Maxalt
(Rizatriptan)

Amerge
(Naratriptan)

Fioricet
(Butalbital / Acetaminophen / Caffeine)

Fiorinal
(Butalbital / Aspirin / Caffeine)

Relpax
(Eletriptan)

Frova
(Frovatriptan)

Axert
(Almotriptan)

Imitrex
(Sumatriptan)

Zomig
(Zolmitriptan)

Treats migraine headaches. Maxalt (Rizatriptan) is great for relieving short migraines, but doesn't work as well for long-lasting headaches.Coming soon.Treats tension headaches. Fioricet (Butalbital / Acetaminophen / Caffeine) works well for tension headaches, but isn’t recommended due to the ability to overuse it and have withdrawal symptoms.Coming soon.Coming soon.Coming soon.Coming soon.Treats migraine headaches. Imitrex (Sumatriptan) is an excellent choice for acute migraine relief, but you might need another medication to prevent headaches.Coming soon.
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Reviews & ratings
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Reviews for Imitrex (Sumatriptan)
77%
1% vs. Maxalt (Rizatriptan)
73%
+6% vs. Maxalt (Rizatriptan)
15%
+7% vs. Maxalt (Rizatriptan)

Not enough reviews for this drug. Help someone out, leave a review!

Side effects
MaxaltAmergeFioricetFiorinalRelpaxFrovaAxertImitrexZomig

We haven’t found good data for Maxalt side effects.

FDA side effect reports for Maxalt »

We haven’t found good data for Amerge side effects.

FDA side effect reports for Amerge »

We haven’t found good data for Fioricet side effects.

FDA side effect reports for Fioricet »

We haven’t found good data for Fiorinal side effects.

FDA side effect reports for Fiorinal »

We haven’t found good data for Relpax side effects.

FDA side effect reports for Relpax »
  • Fatigue 3%
  • Dizziness 3%
  • Tingling sensation 2%
  • Flushing 2%
  • Dry mouth 2%
  • Headache 1%
  • Indigestion 1%
  • Chest pain 1%
  • Hot or cold sensation 1%
  • Skeletal pain 1%
More Frova side effects »

We haven’t found good data for Axert side effects.

FDA side effect reports for Axert »
  • Pain and other pressure sensations 4%
  • Paresthesia (all types) 3%
  • Atypical sensations 2%
  • Chest - pain/tightness/pressure and/or heaviness 1%
  • Pain - location specified 1%
  • Sensation warm/cold 1%
  • Other - pressure/tightness/ heaviness 1%
More Imitrex side effects »

We haven’t found good data for Zomig side effects.

FDA side effect reports for Zomig »
How it works
MaxaltAmergeFioricetFiorinalRelpaxFrovaAxertImitrexZomig
Maxalt (Rizatriptan) is a triptan medication that treats migraine headaches. It releases serotonin, which lowers the inflammation that causes headaches.Coming soon.Fioricet (Butalbital / Acetaminophen / Caffeine) is a combination of three medications. Butalbital is a barbiturate that relaxes you. Acetaminophen relieves pain, and caffeine narrows the blood vessels that otherwise cause headaches.Coming soon.Coming soon.Coming soon.Coming soon.Imitrex (Sumatriptan) is a triptan medication that treats migraine headaches. It releases serotonin, which lowers the inflammation that causes headaches.Coming soon.
Type of medication
MaxaltAmergeFioricetFiorinalRelpaxFrovaAxertImitrexZomig
Antimigraine
Triptan
Prescription only
Coming soon.
Pain reliever
Barbiturate
Prescription only
Coming soon.
Coming soon.
Coming soon.
Coming soon.
Antimigraine
Triptan
Prescription only
Coming soon.
Available as
MaxaltAmergeFioricetFiorinalRelpaxFrovaAxertImitrexZomig
  • Pill
  • Dissolving tablet
  • Pill
  • Pill
  • Oral solution
  • Pill
  • Pill
  • Pill
  • Pill
  • Pill
  • Injection
  • Nasal spray
  • Pill
  • Dissolving tablet
  • Nasal spray
Used for (click to learn more)
MaxaltAmergeFioricetFiorinalRelpaxFrovaAxertImitrexZomig
  • Migraine (Acute)
  • Tension-type headache
  • Migraine (Acute)
  • Migraine (Acute)
  • Migraine (Acute)
  • Migraine (Acute)
Risk factors for serious side effects
MaxaltAmergeFioricetFiorinalRelpaxFrovaAxertImitrexZomig
  • History of heart problems
  • High blood pressure
  • High cholesterol
  • Diabetes
  • Being overweight or obese
  • Smoking
  • History of heart problems
  • High blood pressure
  • High cholesterol
  • Diabetes
  • Being overweight or obese
  • Smoking
    • Patients taking SSRIs and SNRIs
    • History of high blood pressure
    • History of seizures
    • Phenylketonuria (PKU)
    Detailed Maxalt (Rizatriptan) risks & warnings »
    Coming soon.Coming soon.Coming soon.Coming soon.Coming soon.Coming soon.Coming soon.Coming soon.
    Pregnancy category
    MaxaltAmergeFioricetFiorinalRelpaxFrovaAxertImitrexZomig
    CFDA pregnancy category (Weigh risks vs. benefits)

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    See the FDA package insert
    CFDA pregnancy category (Weigh risks vs. benefits)

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    See the FDA package insert
    CFDA pregnancy category (Weigh risks vs. benefits)

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    See the FDA package insert
    CFDA pregnancy category (Weigh risks vs. benefits)

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    See the FDA package insert
    CFDA pregnancy category (Weigh risks vs. benefits)

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    See the FDA package insert
    CFDA pregnancy category (Weigh risks vs. benefits)

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    See the FDA package insert
    CFDA pregnancy category (Weigh risks vs. benefits)

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    See the FDA package insert
    CFDA pregnancy category (Weigh risks vs. benefits)

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    See the FDA package insert
    CFDA pregnancy category (Weigh risks vs. benefits)

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    See the FDA package insert
    Alcohol
    No specific alcohol-related info.No specific alcohol-related info.
    • While taking Fioricet (Butalbital / Acetaminophen / Caffeine), don’t drink alcohol or take other drugs that slow your body down.
    No specific alcohol-related info.No specific alcohol-related info.No specific alcohol-related info.No specific alcohol-related info.No specific alcohol-related info.No specific alcohol-related info.
    Food
    No specific food-related info.No specific food-related info.No specific food-related info.No specific food-related info.No specific food-related info.No specific food-related info.No specific food-related info.No specific food-related info.No specific food-related info.
    Kidneys and liver
    No specific kidneys and liver-related info.No specific kidneys and liver-related info.No specific kidneys and liver-related info.No specific kidneys and liver-related info.No specific kidneys and liver-related info.No specific kidneys and liver-related info.No specific kidneys and liver-related info.No specific kidneys and liver-related info.No specific kidneys and liver-related info.
    Sex
    No specific sex-related info.No specific sex-related info.No specific sex-related info.No specific sex-related info.No specific sex-related info.No specific sex-related info.No specific sex-related info.No specific sex-related info.No specific sex-related info.
    Sleep
    No specific sleep-related info.No specific sleep-related info.No specific sleep-related info.No specific sleep-related info.No specific sleep-related info.No specific sleep-related info.No specific sleep-related info.
    • Imitrex (Sumatriptan) can make you drowsy, so avoid activities that need you to be fully alert until you know how it affects you.
    No specific sleep-related info.
    Weight
    No specific weight-related info.No specific weight-related info.No specific weight-related info.No specific weight-related info.No specific weight-related info.No specific weight-related info.No specific weight-related info.No specific weight-related info.No specific weight-related info.
    Upsides and benefits
    MaxaltAmergeFioricetFiorinalRelpaxFrovaAxertImitrexZomig
    • Triptans like Maxalt (Rizatriptan) are considered the first-choice treatment to relieve moderate to severe migraine-type headaches.
    • It can also be used to treat tension-type headaches.
    • Not all triptans work the same way for people, so you can try multiple ones to find the right medication for you.
    • You don't need to drink water with the orally disintegrating tablet for it to work, so this could be a good medication for people who can't keep water down when they have a migraine.
    Coming soon.
    • Fioricet (Butalbital / Acetaminophen / Caffeine) works better and faster in treating tension headaches than the combination of acetaminophen and codeine.
    • Fioricet (Butalbital / Acetaminophen / Caffeine) doesn’t cost much since it's available as a generic medication.
    • Fioricet (Butalbital / Acetaminophen / Caffeine) has very few side effects.
    • It has been widely used for a long time.
    Coming soon.Coming soon.Coming soon.Coming soon.
    • Comes in several forms. Ask your doctor if you should use the pill, nasal spray, patch, or injection.
    • A combination of forms can be used if symptoms do not improve.
    • The nasal spray and injectable forms work very quickly.
    • It's generally safe to use if you are pregnant.
    • Comes in a generic form, so it can be pretty cheap.
    Coming soon.
    Downsides and risks
    MaxaltAmergeFioricetFiorinalRelpaxFrovaAxertImitrexZomig
    • Maxalt (Rizatriptan) doesn’t prevent migraines or tension headaches, but only works once the headache starts.
    • It can cause rebound headaches if it’s used too often.
    • You need to wait at least 2 hours after your first dose to take a second dose.
    • May not be the best choice if you have long, drawn-out headaches. Ask your doctor about other triptans that can last longer than Maxalt (Rizatriptan).
    • Not a good choice if you have heart disease or if you’re pregnant or breast-feeding.
    Coming soon.
    • Fioricet (Butalbital / Acetaminophen / Caffeine) isn't the first choice medication for treating tension headaches.
    • It's not a good medication for long-term use.
    • Overuse of Fioricet (Butalbital / Acetaminophen / Caffeine) can lead to chronic tension headaches.
    • Fioricet (Butalbital / Acetaminophen / Caffeine) can cause dangerous withdrawal symptoms, intoxication, and dependence.
    • Taking Fioricet (Butalbital / Acetaminophen / Caffeine) can decrease your ability to drive a car, or operate machinery.
    Coming soon.Coming soon.Coming soon.Coming soon.
    • The oral and nasal versions of Imitrex (Sumatriptan) have an unpleasant after-taste.
    • Does not prevent migraine headaches; it only treats them once they start.
    • Must wait 1 hour before using second injection.
    • Can cause rebound (more) headaches if Imitrex (Sumatriptan) is used too often.
    • Need to have your blood pressure checked often, especially if you're pregnant.
    Coming soon.
    Tips from our pharmacists for people taking the medication
    MaxaltAmergeFioricetFiorinalRelpaxFrovaAxertImitrexZomig
    • Take Maxalt (Rizatriptan) as soon as you feel you’re getting a headache or experience warning signs like being sensitive to light or sound.
    • If you're taking other medicines to control your headaches (like propranolol), the dose of Maxalt (Rizatriptan) will be different.
    • Let your doctor know if your headaches don’t go away after taking [name-common] or if you have more than 4 migraines per month.
    • It’s available in two different dosage forms, a tablet you take by mouth and an orally disintegrating tablet (Maxalt-MLT) you place on your tongue to let it dissolve.
    • Lie down in a dark room after taking Maxalt (Rizatriptan) to help ease pain. Ask your doctor about other medicines that can help prevent your headaches.
    Coming soon.
    • Take Fioricet (Butalbital / Acetaminophen / Caffeine) as soon as your headache starts, then lie down in a dark room to help ease the pain.
    • Be sure to take each dose with a full glass of water.
    • Take your time getting up from sitting or lying down while taking Fioricet (Butalbital / Acetaminophen / Caffeine) to decrease your chances of feeling dizzy.
    • Be sure to limit how much caffeine and chocolate you take while on Fioricet (Butalbital / Acetaminophen / Caffeine) since it can cause nervousness, shakiness, and a fast heartbeat.
    • While taking Fioricet (Butalbital / Acetaminophen / Caffeine), don’t drink alcohol or take other drugs that slow your body down.
    • Don't take other forms of acetaminophen (Tylenol) while taking Fioricet (Butalbital / Acetaminophen / Caffeine), since taking too much can lead to liver problems.
    Coming soon.Coming soon.Coming soon.Coming soon.
    • Take it as soon as your headache starts.
    • If you use the nasal spray, be sure to blow your nose before using it.
    • If you use the patch, put it on a dry area free of scars, tattoos, or other cuts and scrapes. Be sure to press the button to activate it.
    • If you use the injection, you can use a second injection if you still have a headache after an hour. If you have symptoms 2 hours after the injection, switch to the pill version.
    • Imitrex (Sumatriptan) can make you drowsy, so avoid activities that need you to be fully alert until you know how it affects you.
    • Lie down in a dark room after taking Imitrex (Sumatriptan) to help ease the pain.
    Coming soon.
    Learn more
    More about MaxaltSide effectsReviews & ratingsAlternativesFDA package insert
    More about AmergeSide effectsReviews & ratingsFDA package insert
    More about FioricetSide effectsReviews & ratingsFDA package insert
    More about FiorinalSide effectsReviews & ratingsFDA package insert
    More about RelpaxSide effectsReviews & ratingsFDA package insert
    More about FrovaSide effectsFDA package insert
    More about AxertSide effectsReviews & ratingsFDA package insert
    More about ImitrexSide effectsReviews & ratingsFDA package insert
    More about ZomigSide effectsReviews & ratingsFDA package insert