Prescription onlyLower-cost generic availableClass: Neuro/psych



Prescription onlyLower-cost generic availableClass: Neuro/psych
Back to: Full Site NavigationSkip to: side effects sectionSkip to: What to expect sectionSkip to: Risks and warnings sectionSkip to: Common concerns from users and pharmacists

Treats appetite and weight loss in people with AIDS, and pain in people with cancer.

Skip Upsides & Downsides section. Skip to side effects section.

Our bottom line

Megace (megestrol) is good for treating appetite and weight loss in people with advanced cancer or AIDS, without causing the side effects of steroids.

Price and discounts
Prices and coupons for 60 (40mg) tablets of megestrol


  • Compared to other medicines, Megace (megestrol) has fewer side effects.
  • Megace (megestrol) is available in generic and comes in a pleasant tasting liquid that is easy to take.
  • Megace (megestrol) comes in 2 different strengths, which can lower the amount of liquid you have to take.


  • Can make it difficult to get or maintain an erection.
  • Can cause vaginal bleeding.
  • If you've ever had blood clots, Megace (megestrol) can make you more likely to have them again.
How it works

Megace (megestrol) is a progestin derivative (steroid hormone). In people who have endometrial and breast cancer, it lowers certain hormones created in tumors that are responsible for causing pain. It is not clear how Megace (megestrol) treats appetite and weight loss.

What to expect when you take Megace (megestrol) for Appetite & weight loss

Skip what to expect section. Skip to Risks & Warnings section.
Skip side effects section. Skip to What to Expect and Pharmacists Tips section.

Side effect rates for Megace (megestrol)

102 From clinical trials of Megace / Appetite & weight loss (100mg daily)
  • Diarrhea
  • Headache
  • Skin rash
  • Fever
  • Nausea
  • Unable to get or maintain an erection
  • Lower sexual desire
  • Trouble sleeping
  • Low red blood cells
  • Vomiting

Risks and Warnings for Megace (megestrol)

Skip risks section. Skip to common concerns section.
    • Higher risk if:
    • Pregnancy

    If you're pregnant, don't take Megace (megestrol) because it can harm your fetus. Use birth control while you're taking Megace (megestrol) to prevent an unwanted pregnancy from happening. Talk to your doctor if this is a problem.

Common concerns from people taking Megace (megestrol)

Final section. Do you want to return to drug navigation?