Prescription onlyLower-cost generic availableClass: Cardiovascular

Loniten Alternatives

(minoxidil)

Prescription onlyLower-cost generic availableClass: Cardiovascular
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Compare Loniten (minoxidil) to alternatives

These medications are comparable to Loniten (minoxidil) or used for similar purposes.

Loniten
(minoxidil)

hydralazine

Isordil
(isosorbide dinitrate)

Nitrostat
(nitroglycerin)

Lowers blood pressure. Loniten (Minoxidil) should only be used to treat blood pressure when other medications can’t.Coming soon.Relieves chest pain. Isosorbide dinitrate is good for chest pain, but you have to be able to stick to your dosing schedule or it won't work as well.Relieves chest pain. Nitroglycerin is the fastest-working medicine to relieve chest pain, but make sure to sit down before taking it.
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Reviews & ratings
Filter group. All currently selected
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Not enough reviews for this treatment. Help someone out, leave a review!

Have you used Loniten (minoxidil)?
Worth itNot sureNot worth it

Not enough reviews for this treatment. Help someone out, leave a review!

Have you used Hydralazine?
Worth itNot sureNot worth it
Reviews for Isordil
46%
+54% better vs. Minoxidil
24%
+26% better vs. Minoxidil
20%
+20% better vs. Minoxidil
Have you used Isordil (isosorbide dinitrate)?
Worth itNot sureNot worth it
Reviews for Nitrostat
41%
+59% better vs. Minoxidil
51%
-1% worse vs. Minoxidil
21%
+21% better vs. Minoxidil
Have you used Nitrostat (nitroglycerin)?
Worth itNot sureNot worth it
Side effects
MinoxidilHydralazineIsordilNitrostat

We haven’t found good data for Minoxidil side effects.

FDA side effect reports for Minoxidil »

We haven’t found good data for Hydralazine side effects.

FDA side effect reports for Hydralazine »

The Isordil FDA package insert doesn’t have numbers about how common side effects are.

More about Isordil side effects »
  • Headache 45%
  • Lightheadedness 2%
  • Low blood pressure 4%
More Nitrostat side effects »
How it works
MinoxidilHydralazineIsordilNitrostat
Loniten (Minoxidil) is a vasodilator. It helps lower blood pressure by relaxing and opening the blood vessels in your arms, legs, and organs.Coming soon.Isosorbide dinitrate is a nitrate. It dilates blood vessels all over the body. This makes it less work for the heart to pump, which relieves heart-related chest pain.Nitroglycerin is a nitrate. It dilates blood vessels all over the body. This makes it less work for the heart to pump, which relieves heart-related chest pain.
Type of medication
MinoxidilHydralazineIsordilNitrostat
Prescription onlyPrescription onlyPrescription only
Available as
MinoxidilHydralazineIsordilNitrostat
  • Pill
  • Pill
  • Pill
  • Extended release
  • Dissolving tablet
  • Pill
  • Extended release
  • Patch
  • Mouth spray
  • Cream, gel, or ointment
  • Rectal gel or ointment
Used for
MinoxidilHydralazineIsordilNitrostat
  • Essential Hypertension
Risk factors for serious side effects
MinoxidilHydralazineIsordilNitrostat
    Detailed Loniten (minoxidil) risks & warnings »
      Coming soon.
      • Age 65 years or older
      • Taking drugs for erectile dysfunction
      • Alcohol use
      Detailed Isordil (isosorbide dinitrate) risks & warnings »
      • Concurrent use of erectile dysfunction medicine
      • Age 65 years or older
      • Alcohol use
      • Long term use
      Detailed Nitrostat (nitroglycerin) risks & warnings »
      Pregnancy

      Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

      Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

      Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

      Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

      Alcohol
      MinoxidilHydralazineIsordilNitrostat
      No alcohol related info.No alcohol related info.
      • Don't drink alcohol while taking this medicine. It can make you really dizzy.
      • Don't drink alcohol while taking this medicine. It can make dizziness worse.
      Food
      MinoxidilHydralazineIsordilNitrostat
      • You can take Loniten (Minoxidil) with or without food.
      No food related info.No food related info.No food related info.
      Kidneys and liver
      MinoxidilHydralazineIsordilNitrostat
      • Decreases your chance of stroke, heart attack, and kidney problems.
      No kidneys and liver related info.No kidneys and liver related info.No kidneys and liver related info.
      Pain
      MinoxidilHydralazineIsordilNitrostat
      No pain related info.No pain related info.No pain related info.
      • Usually relieves chest pain in 1 to 5 minutes. If pain continues, you can take up to 3 doses, with 5 minutes in between each dose. Call 911 or go to the hospital if you've taken a second dose.
      • First-choice treatment for quick relief of heart-related chest pain (angina).
      Upsides and benefits
      MinoxidilHydralazineIsordilNitrostat
      • In a clinical trial, 75% of people using Loniten (Minoxidil) were able to greatly decrease their blood pressure.
      • Decreases your chance of stroke, heart attack, and kidney problems.
      • Loniten (Minoxidil) comes in a generic form, so it’s pretty cheap.
      • Could be safe to use if you're pregnant.
      Coming soon
      • Treats and prevents heart-related chest pain (angina) from the narrowing of heart blood vessels (coronary artery disease).
      • First-choice treatment for quick relief of heart-related chest pain (angina).
      • Can also be used to prevent chest pain from happening.
      • Available in various forms that take effect at different speeds and stay in your system for different lengths of time. Sublingual form works the fastest (1-3 minutes) but lasts the shortest in your body (25 minutes), while the patch form takes the longest to start working (30 minutes) but lasts the longest (10-12 hours). Your doctor can help you find the one that's best for you.
      Downsides and risks
      MinoxidilHydralazineIsordilNitrostat
      • You'll need to take a diuretic or “water pill” to get rid of the salt and water your body hangs onto when taking Loniten (Minoxidil).
      • You'll also need to take a heart medication like a beta-blocker to slow your heart from beating too fast.
      • In some people, Loniten (Minoxidil) can cause chest pain, heart attack, or heart failure.
      • It can take a few weeks after starting Loniten (Minoxidil) before you feel the full benefits.
      Coming soon
      • You can develop tolerance to this medicine over time, which means that the same dose becomes less effective. You have to stick to a really specific dosing schedule to prevent this from happening.
      • Headaches are normal with this medicine and they go away as your body gets used to it, but they can be severe or not tolerable for some people.
      • You can develop tolerance to this medicine over time, which means that the same dose becomes less effective. You have to stick to a really specific dosing schedule for the extended-release, ointment, and patch forms to prevent this from happening.
      • Headaches are normal with this medicine and they go away as your body gets used to it, but they can be severe or not tolerable for some people.
      Tips from our pharmacists for people taking the medication
      MinoxidilHydralazineIsordilNitrostat
      • Loniten (Minoxidil) works best over time, so even if you're feeling okay, be sure to take it at the same time everyday.
      • You can take Loniten (Minoxidil) with or without food.
      • Avoid activities that need you to be fully alert like driving, until you know how Loniten (Minoxidil) affects you.
      • If you're sitting or lying down, get up slowly to minimize dizziness.
      • Be sure to have your blood pressure and heart rate checked often while taking Loniten (Minoxidil).
      • Talk to your doctor before taking medications that can raise your blood pressure, like cough or cold medications, diet pills, stimulants, ibuprofen, and some natural products.
      Coming soon
      • Can cause headaches, dizziness, lightheadedness, or fainting.
      • Don't drink alcohol while taking this medicine. It can make you really dizzy.
      • Tell your doctor if you're taking any medicine for erectile dysfunction.
      • Don't stop taking this medicine suddenly.
      • Can cause headaches, dizziness, lightheadedness, or fainting. Sit down before taking this medicine in case you get dizzy.
      • Take it exactly as instructed by your doctor.
      • Usually relieves chest pain in 1 to 5 minutes. If pain continues, you can take up to 3 doses, with 5 minutes in between each dose. Call 911 or go to the hospital if you've taken a second dose.
      • Don't drink alcohol while taking this medicine. It can make dizziness worse.
      • Tell your doctor if you're taking any medicine for erectile dysfunction.
      Learn more
      More about MinoxidilSide effectsReviews & ratingsAlternativesFDA package insert
      Have you used Loniten (minoxidil)?
      Worth itNot sureNot worth it
      More about HydralazineSide effectsReviews & ratingsFDA package insert
      Have you used Hydralazine?
      Worth itNot sureNot worth it
      More about IsordilSide effectsReviews & ratingsFDA package insert
      Have you used Isordil (isosorbide dinitrate)?
      Worth itNot sureNot worth it
      More about NitrostatSide effectsReviews & ratingsFDA package insert
      Have you used Nitrostat (nitroglycerin)?
      Worth itNot sureNot worth it