Prescription onlyLower-cost generic available

Mirapex

(Pramipexole)

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Helps with movement problems.

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Prescription onlyLower-cost generic available

Our pharmacists’ bottom line

Mirapex (Pramipexole) is an effective medicine for Parkinson's disease or restless leg syndrome, but there are potentially serious side effects.

  • In studies, Mirapex (Pramipexole) when taken by itself or with other medicines, was effective in lowering movement fluctuations for people with Parkinson's disease.
  • Mirapex (Pramipexole) is sometimes preferred over other medicines that treat Parkinson's disease in older people since it causes fewer movement and mental fluctuations.
  • Is effective for treating restless leg syndrome.
  • Available in a short-acting and a long-acting form.
  • Mirapex (Pramipexole) isn't a first-choice treatment for Parkinson's disease. It can be used by itself, but it's usually used with other medicines.
  • Mirapex (Pramipexole) can cause hallucinations in older people.
  • Not the best choice if you have kidney problems. Your doctor may have to adjust your dose based on your kidney function.
  • You can't suddenly stop taking Mirapex (Pramipexole). You'll have to slowly lower your dose, especially if you've been using it for a long time.

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Side effects for Mirapex (Pramipexole)

From clinical trials of Mirapex / Advanced Parkinson's disease ( 524)

  • Positional low blood pressurePositional low blood pressure53% for Pramipexole vs.48% for placebo
  • DyskinesiaDyskinesia47% for Pramipexole vs.31% for placebo
  • Extrapyramidal syndromeExtrapyramidal syndrome28% for Pramipexole vs.26% for placebo
  • Sleep difficultySleep difficulty27% for Pramipexole vs.22% for placebo
  • DizzinessDizziness26% for Pramipexole vs.25% for placebo
  • DyskinesiaDyskinesia18% for Pramipexole vs.8% for placebo
  • DyskinesiaDyskinesia17% for Pramipexole vs.8% for placebo
  • HallucinationsHallucinations17% for Pramipexole vs.4% for placebo
  • Accidental injuryAccidental injury17% for Pramipexole vs.15% for placebo
  • Any side effectAny side effect12% for Pramipexole vs.16% for placebo

What to expect when you take Mirapex (Pramipexole)

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Tips from our pharmacists
  • You should start Mirapex (Pramipexole) at a low dose and your doctor will raise the dose slowly. This will help lower your risk of side effects, such as drowsiness and low blood pressure.
  • Can cause intense urges and compulsive behaviors that are hard to control, such as binge eating, gambling, and sexual urges. Talk to your doctor right away if you have any of these feelings.
  • You can suddenly fall asleep without warning while on this medicine. Don't perform any tasks that require mental alertness, like driving, or drinking alcohol until you know how Mirapex (Pramipexole) affects you. Let your doctor know if you have a history of sleep problems.
  • Take Mirapex (Pramipexole) 2 to 3 hours before bedtime for restless leg syndrome.
  • Take Mirapex (Pramipexole) with food if it makes you feel nauseous.

Risks and Warnings for Mirapex (Pramipexole)

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  • Mirapex (Pramipexole) can cause intense urges and compulsive behaviors that are hard to control, such as binge eating, gambling, and sexual urges. Talk to your doctor right away if you have any of these feelings.

Means that some groups have a high risk of experiencing this side effect

Tips from pharmacists and people taking Mirapex (Pramipexole)

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The FDA category for this medication is C. It is advised that you: Weigh risks vs. benefits
Pregnancy
Alcohol
  • Tips from our pharmacists
  • You can suddenly fall asleep without warning while on this medicine. Don't perform any tasks that require mental alertness, like driving, or drinking alcohol until you know how Mirapex (Pramipexole) affects you. Let your doctor know if you have a history of sleep problems.
Food
  • Tips from our pharmacists
  • Take Mirapex (Pramipexole) with food if it makes you feel nauseous.
Kidneys & liver
  • Upsides and downsides from our pharmacists
  • Not the best choice if you have kidney problems. Your doctor may have to adjust your dose based on your kidney function.
  • Risks from our pharmacists
  • Mirapex (Pramipexole) is processed by the kidney. If you have kidney problems, talk to your doctor because you may need a different dose.
Sex
  • Tips from our pharmacists
  • Can cause intense urges and compulsive behaviors that are hard to control, such as binge eating, gambling, and sexual urges. Talk to your doctor right away if you have any of these feelings.
  • Risks from our pharmacists
  • Mirapex (Pramipexole) can cause intense urges and compulsive behaviors that are hard to control, such as binge eating, gambling, and sexual urges. Talk to your doctor right away if you have any of these feelings.
Sleep
  • Tips from our pharmacists
  • You should start Mirapex (Pramipexole) at a low dose and your doctor will raise the dose slowly. This will help lower your risk of side effects, such as drowsiness and low blood pressure.
  • You can suddenly fall asleep without warning while on this medicine. Don't perform any tasks that require mental alertness, like driving, or drinking alcohol until you know how Mirapex (Pramipexole) affects you. Let your doctor know if you have a history of sleep problems.