Prescription onlyLower-cost generic availableClass: Neurology

Mirapex 

(pramipexole)

Prescription onlyLower-cost generic availableClass: Neurology
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Helps with movement problems.

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Our bottom line

Mirapex (Pramipexole) is an effective medicine for Parkinson's disease or restless leg syndrome, but there are potentially serious side effects.

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Best available price for 30 (0.25mg) tablets of pramipexole
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Upsides

  • In studies, Mirapex (Pramipexole) when taken by itself or with other medicines, was effective in lowering movement fluctuations for people with Parkinson's disease.
  • Mirapex (Pramipexole) is sometimes preferred over other medicines that treat Parkinson's disease in older people since it causes fewer movement and mental fluctuations.
  • Is effective for treating restless leg syndrome.
  • Available in a short-acting and a long-acting form.

Downsides

  • Mirapex (Pramipexole) isn't a first-choice treatment for Parkinson's disease. It can be used by itself, but it's usually used with other medicines.
  • Mirapex (Pramipexole) can cause hallucinations in older people.
  • Not the best choice if you have kidney problems. Your doctor may have to adjust your dose based on your kidney function.
  • You can't suddenly stop taking Mirapex (Pramipexole). You'll have to slowly lower your dose, especially if you've been using it for a long time.
How it works

Mirapex (Pramipexole) is a dopamine agonist. It binds to receptors in the brain and helps improve movement in people with Parkinson's disease or restless leg syndrome.

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Side effect rates for Mirapex (pramipexole)

524 From clinical trials of Mirapex / Advanced Parkinson's disease
  • Positional low blood pressure
  • Dyskinesia
  • Extrapyramidal syndrome
  • Sleep difficulty
  • Dizziness
  • Dyskinesia
  • Hallucinations
  • Dyskinesia
  • Accidental injury
  • Any side effect

Risks and Warnings for Mirapex (pramipexole)

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  • Mirapex (Pramipexole) can cause intense urges and compulsive behaviors that are hard to control, such as binge eating, gambling, and sexual urges. Talk to your doctor right away if you have any of these feelings.

Common concerns from people taking Mirapex (pramipexole)

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Pregnancy
Price
  • I discontinued pramipexole due to the requirement to take this drug every day, the common, and unpleasant, side effects and the lack of effectiveness. I also tried ropinirole, with similar effect. The only effective treatment I have found is small to moderate doses of opiods (hydrocodone, oxycodone, oral morphine). The latter also has the advantage of only needing to be taken when symptoms occur, but care must be taken to avoid dependence, particularly with morphine.
Food
  • Take Mirapex (Pramipexole) with food if it makes you feel nauseous.
Kidneys and liver
  • Not the best choice if you have kidney problems. Your doctor may have to adjust your dose based on your kidney function.
  • Mirapex (Pramipexole) is processed by the kidney. If you have kidney problems, talk to your doctor because you may need a different dose.