Over-the-counterLower-cost generic available

Mucinex D

(Guaifenesin / Pseudoephedrine)

  • Extended release
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Breaks up mucus and relieves congestion.

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Over-the-counterLower-cost generic available

Our pharmacists’ bottom line

Mucinex D (Guaifenesin / Pseudoephedrine) is good if you have a stuffy nose and a cough with mucus, but it could keep you up at night.

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  • Mucinex D (Guaifenesin / Pseudoephedrine) is a combination medicine that relieves multiple cold symptoms. It's good to use if you have sinus and chest congestion.
  • Helps loosen the mucus in your airways so that you can cough it up more easily.
  • Works well to clear nasal congestion and help you breathe better.
  • Pseudoephedrine, the decongestant in Mucinex D (Guaifenesin / Pseudoephedrine), can make your heart race or make you feel anxious and restless.
  • Doesn't work as well if you use it for more than 4 days at a time.
  • Although you don't need a prescription to get Mucinex D (Guaifenesin / Pseudoephedrine), you need to show a photo ID to buy it in the drugstore.
  • Mucinex D (Guaifenesin / Pseudoephedrine) isn’t useful if you have a dry cough.

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Side effects for Mucinex D (Guaifenesin / Pseudoephedrine)

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These are side effects of Mucinex D (Guaifenesin / Pseudoephedrine) reported to the FDA by people taking it, and by doctors and pharmacists.

0 reports

What to expect when you take Mucinex D (Guaifenesin / Pseudoephedrine)

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Tips from our pharmacists
  • Drink plenty of fluids while taking Mucinex D (Guaifenesin / Pseudoephedrine) because liquid helps break down mucus.
  • Follow age-specific dosing instructions on how much to take. Don't take more than the recommended dose.
  • You need to show an ID to buy Mucinex D (Guaifenesin / Pseudoephedrine) in the drugstore because it contains pseudoephedrine.
  • Don't take Mucinex D (Guaifenesin / Pseudoephedrine) too close to bedtime since it can keep you awake.
  • Can cause an irregular or fast heartbeat, and can raise your blood pressure.

Risks and Warnings for Mucinex D (Guaifenesin / Pseudoephedrine)

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    • Higher risk if:
    • History of high blood pressure

    People taking Mucinex D (Guaifenesin / Pseudoephedrine) and MAO inhibitors together, or up to 14 days apart from each other, can experience very high blood pressure that can cause headaches and strokes. MAOI drugs are used to treat Parkinson's disease, depression, and other emotional conditions. Talk to your doctor or pharmacist if you're taking MAO inhibitors and still want to use a cough medicine.

Means that some groups have a high risk of experiencing this side effect

Tips from pharmacists and people taking Mucinex D (Guaifenesin / Pseudoephedrine)

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The FDA category for this medication is N. It is advised that you: Unknown
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