Over-the-counterLower-cost generic available

Mucinex D Alternatives

(Guaifenesin / Pseudoephedrine)

  • Extended release
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Compare Mucinex D (Guaifenesin / Pseudoephedrine) to alternatives

These medications are comparable to Mucinex D (Guaifenesin / Pseudoephedrine) or used for similar purposes.

Mucinex D
(Guaifenesin / Pseudoephedrine)

Mucinex
(Guaifenesin)

Robitussin
(Guaifenesin)

Mucinex Dm
(Dextromethorphan / Guaifenesin)

Robitussin Dm
(Guaifenesin / Dextromethorphan)

Mucinex Dm
(Dextromethorphan / Guaifenesin)

Delsym
(Dextromethorphan)

Ala-Hist Ir
(Brompheniramine)

Breaks up mucus and relieves congestion. Mucinex D (Guaifenesin / Pseudoephedrine) is good if you have a stuffy nose and a cough with mucus, but it could keep you up at night.Breaks up mucus that causes cough. Mucinex (Guaifenesin) is a useful medicine for loosening congestion in your chest and throat, and it lasts longer than other guaifenesin products.Breaks up mucus that causes cough. Robitussin (Guaifenesin) is a useful medicine for loosening congestion in your chest and throat, but it doesn't last as long as other guaifenesin products.Breaks up mucus and relieves cough. Mucinex Dm (Dextromethorphan / Guaifenesin) is okay for loosening congestion in your chest and throat, but it could prevent you from coughing the mucus up. It comes as an extended-release tablet and a short-acting liquid.Breaks up mucus and relieves cough. Robitussin Dm (Guaifenesin / Dextromethorphan) is okay for loosening congestion in your chest and throat, but it could prevent you from coughing the mucus up. You have to take it more often than other guaifenesin products.Breaks up mucus and relieves cough. Mucinex Dm (Dextromethorphan / Guaifenesin) is okay for loosening congestion in your chest and throat, but it could prevent you from coughing the mucus up. It comes as an extended-release tablet and a short-acting liquid.Relieves coughing. Delsym (Dextromethorphan) is a good option for treating dry cough. It's not safe to take with MAO inhibitors though.Coming soon.
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Reviews & ratings
Button Group. All currently active
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5.155573376102646Mucinex D
Reviews for Mucinex D (Guaifenesin / Pseudoephedrine)
76%
of people say Mucinex D (Guaifenesin / Pseudoephedrine) is worth it
41%
say it works well
7%
say it's a big hassle
Reviews for Mucinex (Guaifenesin)
78%
+2% vs. Mucinex D (Guaifenesin / Pseudoephedrine)
47%
+6% vs. Mucinex D (Guaifenesin / Pseudoephedrine)
7%
Same vs. Mucinex D (Guaifenesin / Pseudoephedrine)

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Reviews for Robitussin Dm (Guaifenesin / Dextromethorphan)
75%
1% vs. Mucinex D (Guaifenesin / Pseudoephedrine)
37%
4% vs. Mucinex D (Guaifenesin / Pseudoephedrine)
7%
Same vs. Mucinex D (Guaifenesin / Pseudoephedrine)

Not enough reviews for this drug. Help someone out, leave a review!

Reviews for Delsym (Dextromethorphan)
64%
12% vs. Mucinex D (Guaifenesin / Pseudoephedrine)
31%
10% vs. Mucinex D (Guaifenesin / Pseudoephedrine)
12%
5% vs. Mucinex D (Guaifenesin / Pseudoephedrine)

Not enough reviews for this drug. Help someone out, leave a review!

Side effects
Mucinex DMucinexRobitussinMucinex DMRobitussin DMMucinex DMDelsymBrompheniramine

We haven’t found good data for Mucinex D side effects.

FDA side effect reports for Mucinex D »

We haven’t found good data for Mucinex side effects.

FDA side effect reports for Mucinex »

We haven’t found good data for Robitussin side effects.

FDA side effect reports for Robitussin »

We haven’t found good data for Mucinex DM side effects.

FDA side effect reports for Mucinex DM »

We haven’t found good data for Robitussin DM side effects.

FDA side effect reports for Robitussin DM »

We haven’t found good data for Mucinex DM side effects.

FDA side effect reports for Mucinex DM »

We haven’t found good data for Delsym side effects.

FDA side effect reports for Delsym »

We haven’t found good data for Brompheniramine side effects.

FDA side effect reports for Brompheniramine »
How it works
Mucinex DMucinexRobitussinMucinex DMRobitussin DMMucinex DMDelsymBrompheniramine
Mucinex D (Guaifenesin / Pseudoephedrine) is a combination medicine. Guaifenesin (an expectorant) breaks up and thins out mucus. Pseudoephedrine (a decongestant) clears your sinuses.Mucinex (Guaifenesin) is an expectorant. It contains guaifenesin, which thins and loosens mucus, making it easier to cough out.Robitussin (Guaifenesin) is an expectorant. It contains guaifenesin, which thins and loosens mucus, making it easier to cough out.Mucinex Dm (Dextromethorphan / Guaifenesin) is a combination medicine. Guaifenesin is an expectorant that breaks up and thins out mucus. Dextromethorphan is a cough suppressant.Robitussin Dm (Guaifenesin / Dextromethorphan) is a combination medicine. Guaifenesin is an expectorant that breaks up and thins out mucus. Dextromethorphan is a cough suppressant.Mucinex Dm (Dextromethorphan / Guaifenesin) is a combination medicine. Guaifenesin is an expectorant that breaks up and thins out mucus. Dextromethorphan is a cough suppressant.Delsym (Dextromethorphan) is a cough suppressant.Coming soon.
Type of medication
Mucinex DMucinexRobitussinMucinex DMRobitussin DMMucinex DMDelsymBrompheniramine
ExpectorantDecongestantOver-the-counter
ExpectorantOver-the-counter
ExpectorantOver-the-counter
Cough suppressantExpectorantOver-the-counter
ExpectorantCough suppressantOver-the-counter
Cough suppressantExpectorantOver-the-counter
Cough suppressantOver-the-counter
Coming soon.
Available as
Mucinex DMucinexRobitussinMucinex DMRobitussin DMMucinex DMDelsymBrompheniramine
  • Extended release
  • Extended release
  • Liquid
  • Liquid
  • Pill
  • Extended release
  • Liquid
  • Liquid
  • Pill
  • Extended release
  • Liquid
  • Pill
  • Liquid extended release
  • Pill
  • Liquid
Used for (click to learn more)
Mucinex DMucinexRobitussinMucinex DMRobitussin DMMucinex DMDelsymBrompheniramine
  • Allergic rhinitis Anaphylaxis
Risk factors for serious side effects
Mucinex DMucinexRobitussinMucinex DMRobitussin DMMucinex DMDelsymBrompheniramine
  • History of high blood pressure
  • History of heart problems
  • Age 65 years or older
    Detailed Mucinex D (Guaifenesin / Pseudoephedrine) risks & warnings »
    Coming soon.Coming soon.Coming soon.Coming soon.Coming soon.Coming soon.Coming soon.
    Pregnancy category
    Mucinex DMucinexRobitussinMucinex DMRobitussin DMMucinex DMDelsymBrompheniramine
    NFDA pregnancy category (Unknown)

    The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

    See the FDA package insert
    NFDA pregnancy category (Unknown)

    The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

    See the FDA package insert
    NFDA pregnancy category (Unknown)

    The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

    See the FDA package insert
    NFDA pregnancy category (Unknown)

    The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

    See the FDA package insert
    NFDA pregnancy category (Unknown)

    The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

    See the FDA package insert
    NFDA pregnancy category (Unknown)

    The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

    See the FDA package insert
    NFDA pregnancy category (Unknown)

    The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

    See the FDA package insert
    NFDA pregnancy category (Unknown)

    The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

    See the FDA package insert
    Alcohol
    No specific alcohol-related info.
    • Mucinex (Guaifenesin) is alcohol- and sugar-free.
    No specific alcohol-related info.No specific alcohol-related info.No specific alcohol-related info.No specific alcohol-related info.No specific alcohol-related info.No specific alcohol-related info.
    Food
    No specific food-related info.No specific food-related info.No specific food-related info.No specific food-related info.No specific food-related info.No specific food-related info.No specific food-related info.No specific food-related info.
    Kidneys and liver
    No specific kidneys and liver-related info.No specific kidneys and liver-related info.No specific kidneys and liver-related info.No specific kidneys and liver-related info.No specific kidneys and liver-related info.No specific kidneys and liver-related info.No specific kidneys and liver-related info.No specific kidneys and liver-related info.
    Sex
    No specific sex-related info.No specific sex-related info.No specific sex-related info.No specific sex-related info.No specific sex-related info.No specific sex-related info.No specific sex-related info.No specific sex-related info.
    Sleep
    No specific sleep-related info.No specific sleep-related info.No specific sleep-related info.No specific sleep-related info.No specific sleep-related info.No specific sleep-related info.No specific sleep-related info.No specific sleep-related info.
    Weight
    No specific weight-related info.No specific weight-related info.No specific weight-related info.No specific weight-related info.No specific weight-related info.No specific weight-related info.No specific weight-related info.No specific weight-related info.
    Upsides and benefits
    Mucinex DMucinexRobitussinMucinex DMRobitussin DMMucinex DMDelsymBrompheniramine
    • Mucinex D (Guaifenesin / Pseudoephedrine) is a combination medicine that relieves multiple cold symptoms. It's good to use if you have sinus and chest congestion.
    • Helps loosen the mucus in your airways so that you can cough it up more easily.
    • Works well to clear nasal congestion and help you breathe better.
    • Mucinex (Guaifenesin) reduces the thickness and amount of mucus in your throat and chest.
    • Lasts longer than some other products that contain guaifenesin, such as Robitussin, because it's an extended-release form.
    • Available in liquid and tablet forms.
    • Mucinex (Guaifenesin) is alcohol- and sugar-free.
    • It’s available at the drugstore either by itself or in combination with other medications to treat cold and flu symptoms.
    • Robitussin (Guaifenesin) reduces the thickness and amount of mucus in your throat and chest.
    • Available in multiple forms.
    • Can be used in children 12 years and older.
    • It’s available at the drugstore either by itself or in combination with other medications to treat cold and flu symptoms.
    • Mucinex Dm (Dextromethorphan / Guaifenesin) is a combination medicine that relieves multiple cold symptoms. It's good to use if you have chest congestion and a cough.
    • Helps loosen the mucus and phlegm that builds up in productive and wet coughs.
    • The extended release version of Mucinex DM lasts up to 12 hours.
    • Robitussin Dm (Guaifenesin / Dextromethorphan) is a combination medicine that relieves multiple cold symptoms. It's good to use if you have chest congestion and a cough.
    • Helps loosen the mucus and phlegm that builds up and causes productive, wet coughs.
    • Mucinex Dm (Dextromethorphan / Guaifenesin) is a combination medicine that relieves multiple cold symptoms. It's good to use if you have chest congestion and a cough.
    • Helps loosen the mucus and phlegm that builds up in productive and wet coughs.
    • The extended release version of Mucinex DM lasts up to 12 hours.
    • Good for treating dry cough.
    • Available in drugstores either by itself or in combination with other medications to treat cold and allergy symptoms.
    • Available as a liquid and a tablet.
    • Some products relieve cough for up to 12 hours.
    Coming soon.
    Downsides and risks
    Mucinex DMucinexRobitussinMucinex DMRobitussin DMMucinex DMDelsymBrompheniramine
    • Pseudoephedrine, the decongestant in Mucinex D (Guaifenesin / Pseudoephedrine), can make your heart race or make you feel anxious and restless.
    • Doesn't work as well if you use it for more than 4 days at a time.
    • Although you don't need a prescription to get Mucinex D (Guaifenesin / Pseudoephedrine), you need to show a photo ID to buy it in the drugstore.
    • Mucinex D (Guaifenesin / Pseudoephedrine) isn’t useful if you have a dry cough.
    • Mucinex (Guaifenesin) is more expensive than other medications that treat congestion.
    • Mucinex (Guaifenesin) isn’t useful if you have a dry cough.
    • You need to drink a lot of fluids while taking this medication or it won't work as well.
    • Can cause nausea, headache, and an upset stomach.
    • Robitussin (Guaifenesin) doesn't last as long as other products that contain guaifenesin. Mucinex's extended release form lasts 12 hours and Robitussin (Guaifenesin)'s lasts 8 hours.
    • Robitussin (Guaifenesin) isn’t useful if you have a dry cough.
    • You need to drink a lot of fluids while taking this medication or it won't work as well.
    • Can cause nausea, headache, and an upset stomach.
    • Mucinex Dm (Dextromethorphan / Guaifenesin) isn’t useful if you have a dry cough without mucus or phlegm.
    • The two medications in this product could potentially work against each other. Guaifenesin makes mucus easier to cough up, while dextromethorphan (the "DM" in Mucinex Dm (Dextromethorphan / Guaifenesin)) stops you from coughing.
    • Can cause sleepiness, dizziness, and an upset stomach.
    • The two medications in this product could potentially work against each other. Guaifenesin makes mucus easier to cough up, while dextromethorphan (the "DM" in Robitussin Dm (Guaifenesin / Dextromethorphan)) stops you from coughing.
    • Needs to be taken more often during the day than other products with guaifenesin, like Mucinex.
    • Robitussin Dm (Guaifenesin / Dextromethorphan) isn’t useful if you have a dry cough without mucus or phlegm.
    • Can cause sleepiness, dizziness, and an upset stomach.
    • Mucinex Dm (Dextromethorphan / Guaifenesin) isn’t useful if you have a dry cough without mucus or phlegm.
    • The two medications in this product could potentially work against each other. Guaifenesin makes mucus easier to cough up, while dextromethorphan (the "DM" in Mucinex Dm (Dextromethorphan / Guaifenesin)) stops you from coughing.
    • Can cause sleepiness, dizziness, and an upset stomach.
    • Can't take dextromethorphan if you're taking MAO inhibitors (drugs used to treat Parkinson's disease, depression, and other emotional conditions). If taken together, they will cause dangerously high blood pressure levels.
    • If you're taking this in combination with other cold and allergy medications, you should read labels closely to make sure you're not accidentally taking too much of a single ingredient.
    Coming soon.
    Tips from our pharmacists for people taking the medication
    Mucinex DMucinexRobitussinMucinex DMRobitussin DMMucinex DMDelsymBrompheniramine
    • Drink plenty of fluids while taking Mucinex D (Guaifenesin / Pseudoephedrine) because liquid helps break down mucus.
    • You need to show an ID to buy Mucinex D (Guaifenesin / Pseudoephedrine) in the drugstore because it contains pseudoephedrine.
    • Don't take Mucinex D (Guaifenesin / Pseudoephedrine) too close to bedtime since it can keep you awake.
    • Can cause an irregular or fast heartbeat, and can raise your blood pressure.
    • Follow age-specific dosing instructions on how much to take. Don't take more than the recommended dose.
    • Drink plenty of fluids while taking Mucinex (Guaifenesin) because liquid helps break down mucus.
    • Mucinex (Guaifenesin) only works for coughs with mucus, so don't use it if you have a dry cough.
    • Steam from a humidifier, cool mist vaporizer, or hot shower can also help add moisture to your airways.
    • Follow age-specific dosing instructions on how much to take.
    • Drink plenty of fluids while taking Robitussin (Guaifenesin) because liquid helps break down mucus.
    • Robitussin (Guaifenesin) only works for coughs with mucus, so don't use it if you have a dry cough.
    • Steam from a humidifier, cool mist vaporizer, or hot shower can also help add moisture to your airways.
    • Follow age-specific dosing instructions on how much to take.
    • Cough suppressant starts working in 15 to 30 minutes.
    • Follow age-specific dosing instructions on how much to take. Don't take more than the recommended dose.
    • Drink plenty of fluids while taking Mucinex Dm (Dextromethorphan / Guaifenesin) because liquid helps break down mucus.
    • Drink plenty of fluids while taking Robitussin Dm (Guaifenesin / Dextromethorphan) because liquid helps break down mucus.
    • Cough suppressant starts working in 15 to 30 minutes.
    • Follow age-specific dosing instructions on how much to take. Don't take more than the recommended dose.
    • Cough suppressant starts working in 15 to 30 minutes.
    • Follow age-specific dosing instructions on how much to take. Don't take more than the recommended dose.
    • Drink plenty of fluids while taking Mucinex Dm (Dextromethorphan / Guaifenesin) because liquid helps break down mucus.
    • Cough suppressant starts working in 15 to 30 minutes.
    • Follow age-specific dosing instructions on how much to take. Don't take more than the recommended dose.
    Coming soon.
    Learn more
    More about Mucinex DSide effectsReviews & ratingsAlternativesFDA package insert
    More about MucinexSide effectsReviews & ratingsFDA package insert
    More about RobitussinSide effectsReviews & ratingsFDA package insert
    More about Mucinex DMSide effectsReviews & ratingsFDA package insert
    More about Robitussin DMSide effectsReviews & ratingsFDA package insert
    More about Mucinex DMSide effectsReviews & ratingsFDA package insert
    More about DelsymSide effectsReviews & ratingsFDA package insert
    More about BrompheniramineSide effectsFDA package insert