Prescription or OTCLower-cost generic available



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Relieves pain, fever, and inflammation.

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Prescription or OTCLower-cost generic available

Our bottom line

Aleve (Naproxen) works well for mild to moderate pain and inflammation, and it lasts longer than other NSAIDs.


  • Works well to relieve pain, swelling, and fevers.
  • Good for menstrual cramps, toothaches, body aches, and mild arthritis pain.
  • Lasts longer than Ibuprofen, so you can take it less often.
  • Aleve (Naproxen) works as well as Aspirin and Indomethacin to treat arthritis pain, and causes fewer stomach problems.
  • Although not without side effects, it's been around for a long time and is generally safe for short-term use.
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  • It needs to be taken with food to avoid getting an upset stomach.
  • Can't be taken by pregnant women.
  • It can cause serious kidney and stomach problems (like ulcers and bleeding) the longer you take it.
  • Like all NSAIDs, it can raise your risk of having blood clots, heart attack, or stroke.

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What to expect when you take Aleve (Naproxen) for Pain

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Tips from our pharmacists
  • Starts relieving pain in 30 to 60 minutes.
  • Take it with a meal or a snack to prevent an upset stomach.
  • Can make you bruise or bleed more easily and it can also cause stomach ulcers.
  • Don't take it with other blood thinners, like aspirin, unless your doctor tells you it's safe.
  • Can hurt your kidneys, so don't use it if you have a history of kidney problems.
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Side effects for Aleve (Naproxen)

Manufacturers don’t say how common these side effects are

  • "stomach flu"
  • Abdominal pain
  • Abscess
  • Abscess periodontal
  • Acne
  • Albumin protein in urine
  • Amnesia
  • Aortic valve stenosis
  • Aphthous stomatitis
  • Arterial disorder
  • Bleeding time prolonged
  • Bleeding under the skin
  • Blood urea increased
  • Blood vessel disease
  • Bone disorder
  • Bone pain
  • Breast disorder
  • Breast neoplasm
  • Bronchitis
  • Calculus of kidney
  • Carcinoma
  • Carcinoma breast
  • Cardiac disorder
  • Chest pain
  • Cholestasis
  • Clouded eye lens
  • Colitis ulcerative
  • Constipation
  • Cough
  • Cough increased
  • Deep thrombophlebitis
  • Dehydration
  • Dermatitis contact
  • Diarrhea
  • Difficulty swallowing
  • Disease of a joint
  • Dissecting aortic aneurysm, thoracic
  • Double vision
  • Drowsiness
  • Dry skin
  • Ear disorder
  • Electrocardiogram abnormal
  • Enlargement abdomen
  • Eye disorder
  • Eye pain
  • Fatigue
  • Flu
  • Frequent daytime urination
  • Frequent nighttime urination
  • Gallbladder inflammation
  • Gallstones
  • Gastric disorder
  • Gastric ulcer
  • Haematoma
  • Having high blood pressure
  • Heart block
  • Heart blood vessel disease
  • Heart pounding or racing sensation
  • Heart-related chest pain
  • Heavy periods
  • Hepatic enzyme increased
  • Hepatic impairment
  • Hepatobiliary disease
  • Hepatosplenomegaly
  • Herpes nos
  • Herpes simplex
  • High blood cholesterol
  • Hypersensitivity
  • Hyperuricaemia
  • Immune system disorder
  • Inability to move
  • Incontinence
  • Indigestion
  • Infertility female
  • Inflammation inside the nose
  • Inflammatory bowel disease
  • Itching
  • Joint pain
  • Keratoconjunctivitis
  • Kidney function abnormal
  • Lacrimal disorder
  • Large bruise
  • Lazy eye, blurred vision
  • Leg or ankle swelling
  • Lightheadedness
  • Loss of appetite
  • Loss of bladder control
  • Low acid in blood
  • Low blood potassium
  • Lung disorder
  • Lupus, autoimmune disorder
  • Mediastinal disorder
  • Mental illness
  • Metrorrhagia
  • Middle ear inflammation
  • Migraine
  • Mood swings
  • Mouth ulceration
  • Mucous membrane disorder
  • Muscle rigidity
  • Muscle spasms
  • Muscle weakness
  • Nail disorder
  • Nail-patella syndrome
  • Nausea
  • Neck pain
  • Neck stiffness
  • Neoplasm skin
  • Nephrosclerosis
  • Nervous system disorder
  • Neuritis retrobulbar
  • Nodule
  • Nosebleed
  • Oesophageal achalasia
  • Oesophageal disorder
  • Oesophageal ulcer
  • Optic neuritis
  • Otitis
  • Passing gas
  • Pathological fracture
  • Pelvic pain
  • Prostate disorder
  • Ptosis
  • Pyelonephritis
  • Pyuria
  • Reaction gastrointestinal
  • Rectal disorder
  • Red blood cell abnormality
  • Renal impairment
  • Renal pain
  • Renal tubular disorder
  • Renal tubular necrosis
  • Respiratory disorder
  • Respiratory distress
  • Ringing in the ears
  • Scaly, itchy rash
  • Scleritis
  • Serum creatinine increased
  • Sharp pain from nerve damage
  • Shingles
  • Shortness of breath
  • Sinus inflammation
  • Skin infection
  • Skin necrosis
  • Skin ulcer
  • Sore throat
  • Stiff or rigid muscles
  • Stroke
  • Subcutaneous nodule
  • Subdural haematoma
  • Sugar in urine
  • Sweating
  • Tears
  • Tendon disorder
  • Thirst
  • Thrombophlebitis
  • Tooth disorder
  • Tumor
  • Type 2 diabetes mellitus
  • Unspecified disorder of intestine
  • Urinary retention
  • Urinary tract disorder
  • Urinary tract infection
  • Urine abnormality
  • Uterine spasm
  • Vaginal inflammation
  • Vascular anomaly
  • Vertigo
  • Visual disturbance
  • Vocal cord inflammation
  • Wbc abnormal nos
  • Weight decreased
  • Widening of blood vessels

Risks and Warnings for Aleve (Naproxen)

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    • Higher risk if:
    • History of heart problems
    • High blood pressure
    • High cholesterol
    • Diabetes
    • Smoking

    Aleve (Naproxen) can increase your chance of having blood clots, heart attack, or stroke. Taking the lowest dose that works for you, for the shortest time possible, will lower your risk of having this problem. Don't take Aleve (Naproxen) after having heart surgery for at least two weeks.

    This is a black box warning. The FDA requires this warning when there is a significant risk of serious or life-threatening effects that anyone taking the drug should consider.

Means that some groups have a high risk of experiencing this side effect

Tips from pharmacists and people taking Aleve (Naproxen)

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The FDA category for this medication is C. It is advised that you: Weigh risks vs. benefits
  • Don't drink alcohol when taking diclofenac
  • Upsides and downsides from our pharmacists
  • It needs to be taken with food to avoid getting an upset stomach.
  • Tips from our pharmacists
  • Take it with a meal or a snack to prevent an upset stomach.
  • definitely take with food.
  • Take smaller dose twice a day with food
  • Take it with food
Kidneys and liver
  • Upsides and downsides from our pharmacists
  • It can cause serious kidney and stomach problems (like ulcers and bleeding) the longer you take it.
  • Tips from our pharmacists
  • Can hurt your kidneys, so don't use it if you have a history of kidney problems.
  • Risks from our pharmacists
  • Aleve (Naproxen) is an NSAID that can lower kidney function or cause damage. Taking the lowest dose for the shortest amount of time lowers your risk. Your doctor should check your kidney function if you take Aleve (Naproxen) for any amount of time.
  • Took this in 2008 for pain in hand due to computer overuse. It relieved the pain some but the nausea and drowsiness were unreal.
  • I had my circulation cut off, it fell like it was burning a hole in my stomach (with lots of food), and it made my heart race. I couldn't sleep, was jittery and lacked focus. This stuff is poison and very dangerous!
  • Something about the make up of Naproxen resulted in my body becoming hooked on it after just 1 dose. The second it wore off, I would immediately begin going through withdrawal symptoms and have to sleep a few hrs until it stopped.
  • Forget it, 7 stone I put on in weight due to this medication!!! And that was within a few months, also it did nothing for the pain, in fact made it worse
  • Weight gain