Prescription onlyLower-cost generic availableClass: Neuro/psych



Prescription onlyLower-cost generic availableClass: Neuro/psych
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Treats schizophrenia.

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Our bottom line

Navane (thiothixene) isn't a first choice for treating schizophrenia because of the side effects, but it is cheaper than other medicines.

Price and discounts
Best available price for 30 (5mg) capsules of thiothixene
What is GoodRx?


  • Navane (thiothixene) is available in generic.
  • Navane (thiothixene) is less likely to make you sleepy.


  • Side effects include weight gain and high blood sugar.
  • Navane (thiothixene) can cause low blood pressure, which can cause fainting or falls if you’re not careful.
  • Smoking tobacco can make Navane (thiothixene) work poorly.
How it works

Navane (thiothixene) is a typical antipsychotic. It works by lowering levels of dopamine in the brain. It's believed that schizophrenia might be caused by the brain being too sensitive to changes in dopamine.

What to expect when you take Navane (thiothixene) for Schizophrenia

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Side effect rates for Navane (thiothixene)

Risks and Warnings for Navane (thiothixene)

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    • Higher risk if:
    • People age 65 or older with dementia and psychosis

    Older people who have dementia and psychosis have a higher risk of death if they take antipsychotic medicines like Navane (thiothixene). They shouldn't be given this medicine.

    This is a black box warning. The FDA requires this warning when there is a significant risk of serious or life-threatening effects that anyone taking the drug should consider.

Means that some groups have a high risk of experiencing this side effect

Common concerns from people taking Navane (thiothixene)

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  • Don't drink alcohol while taking Navane (thiothixene).
  • Take Navane (thiothixene) with food so you don't get an upset stomach.
  • Navane (thiothixene) can make you sleepy and unable to focus, so don't drive or do anything requiring concentration for a few hours after taking it until you know how Navane (thiothixene) affects your concentration. This can be worse if you drink alcohol or take medicines that can make you sleepy, such as opioids for pain, benzodiazepines for anxiety, or medicines to help you sleep.
  • Side effects include weight gain and high blood sugar.