Nesina Alternatives

(Alogliptin)

  • Pill
  • Diabetes mellitus type 2
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Compare Nesina (Alogliptin) to alternatives

These medications are comparable to Nesina (Alogliptin) or used for similar purposes.

Nesina
(Alogliptin)

Januvia
(Sitagliptin)

Byetta
(Exenatide)

Glucophage
(Metformin)

Precose
(Acarbose)

Glucotrol
(Glipizide)

Actos
(Pioglitazone)

Lowers your blood sugar. alogliptin is a good add-on treatment if your blood sugar is still too high, but you don't want to use an injectable medicine.Lowers blood sugar. Januvia (Sitagliptin) is a good add-on treatment if your blood sugar is still too high, but you don't want to use an injectable medicine.Lowers your blood sugar. Byetta (Exenatide) helps lower blood sugar for people with diabetes and causes weight loss, but it has to be given by injection and many people have upset stomach.Lowers blood sugar. Glucophage (Metformin) is a very effective medicine to lower blood sugar and the risk of complications and death from diabetes, but it's likely to cause diarrhea for the first few weeks.Coming soon.Lowers blood sugar. Glucotrol (Glipizide) is a very effective oral blood sugar-lowering medicine. It can cause low blood sugar, so make sure you know what the symptoms are and always have a source of sugar nearby.Lowers blood sugar. Actos (Pioglitazone) is a last-choice blood sugar-lowering medicine since it's only moderately effective but has a lot of undesirable side effects.
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Reviews & ratings
Filter group. All currently selected
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Not enough reviews for this drug. Help someone out, leave a review!

Have you used Nesina (Alogliptin)?
Worth itNot sureNot worth it
Reviews for Januvia (Sitagliptin)
43%
57% vs. Nesina (Alogliptin)
34%
66% vs. Nesina (Alogliptin)
17%
17% vs. Nesina (Alogliptin)
138 reviews
Have you used Januvia (Sitagliptin)?
Worth itNot sureNot worth it

Not enough reviews for this drug. Help someone out, leave a review!

Have you used Byetta (Exenatide)?
Worth itNot sureNot worth it
Reviews for Glucophage (Metformin)
65%
35% vs. Nesina (Alogliptin)
46%
54% vs. Nesina (Alogliptin)
16%
16% vs. Nesina (Alogliptin)
929 reviews
Have you used Glucophage (Metformin)?
Worth itNot sureNot worth it

Not enough reviews for this drug. Help someone out, leave a review!

Have you used Precose (Acarbose)?
Worth itNot sureNot worth it
Reviews for Glucotrol (Glipizide)
50%
50% vs. Nesina (Alogliptin)
32%
68% vs. Nesina (Alogliptin)
19%
19% vs. Nesina (Alogliptin)
330 reviews
Have you used Glucotrol (Glipizide)?
Worth itNot sureNot worth it
Reviews for Actos (Pioglitazone)
42%
58% vs. Nesina (Alogliptin)
31%
69% vs. Nesina (Alogliptin)
21%
21% vs. Nesina (Alogliptin)
173 reviews
Have you used Actos (Pioglitazone)?
Worth itNot sureNot worth it
Side effects
NesinaJanuviaByettaMetforminPrecoseGlucotrolActos

We haven’t found good data for Nesina side effects.

FDA side effect reports for Nesina »
  • Common cold 2%
  • Diarrhea 1%
More Januvia side effects »
  • Low blood sugar 33%
  • Nausea 26%
  • Vomiting 14%
  • Headache 10%
  • Diarrhea 10%
  • Constipation 8%
  • Indigestion 6%
  • Feeling jittery 5%
  • Muscle weakness 4%
  • Dizziness 3%
More Byetta side effects »
  • Diarrhea 41%
  • Nausea/vomiting 18%
  • Passing gas 6%
  • Indigestion 3%
  • Muscle weakness 3%
  • Abdominal discomfort 1%
  • Headache 1%
More Metformin side effects »

We haven’t found good data for Precose side effects.

FDA side effect reports for Precose »
  • Passing gas 2%
  • Dizziness 1%
  • Nervousness 1%
More Glucotrol side effects »
  • Swelling due to excess fluid 11%
  • Low blood sugar 8%
  • Ear, nose, or throat infection 4%
  • Sore throat 4%
  • Cardiac failure 2%
  • Muscle pain 2%
  • Headache 2%
  • Back pain 1%
  • Sinus inflammation 1%
More Actos side effects »
How it works
NesinaJanuviaByettaMetforminPrecoseGlucotrolActos
alogliptin is an anti-diabetic drug. It improves your body's ability to use insulin to lower your blood sugar.Januvia (Sitagliptin) is an anti-diabetic drug. It helps your body release more insulin in order to lower blood sugar.Byetta (Exenatide) is a medication for diabetes. It stimulates your body to produce and release more insulin, lower the sugar hormone (glucagon), and slow down digestion.Glucophage (Metformin) is an anti-diabetic drug. It lowers sugar production in your body, decreases sugar absorption in your intestines, and makes your body more sensitive to insulin.Coming soon.Glucotrol (Glipizide) is an anti-diabetic drug. It stimulates your body to make more insulin to lower blood sugar.Actos (Pioglitazone) is an anti-diabetic drug. It improves your body's ability to use insulin to lower your blood sugar.
Type of medication
NesinaJanuviaByettaMetforminPrecoseGlucotrolActos
Coming soon.
Anti-diabetic
DPP-4 inhibitor
Prescription only
Anti-diabetic
Incretin mimetic
Prescription only
Anti-diabetic
Biguanide
Prescription only
Coming soon.
Anti-diabetic
Sulfonylurea
Prescription only
Anti-diabetic
Thiazoladinedione
Prescription only
Available as
NesinaJanuviaByettaMetforminPrecoseGlucotrolActos
  • Pill
  • Pill
  • Injection
  • Pill
  • Extended release
  • Liquid
  • Pill
  • Pill
  • Extended release
  • Pill
Used for (click to learn more)
NesinaJanuviaByettaMetforminPrecoseGlucotrolActos
  • Diabetes mellitus type 2
  • Diabetes mellitus type 2
Risk factors for serious side effects
NesinaJanuviaByettaMetforminPrecoseGlucotrolActos
      Detailed Nesina (Alogliptin) risks & warnings »
          Detailed Januvia (Sitagliptin) risks & warnings »
                • Severe renal impairment
                • End-stage renal disease
                • Severe gastrointestinal disease
                • Gastroparesis
                  Detailed Byetta (Exenatide) risks & warnings »
                  • Kidney problems
                  • Liver problems
                  • Congestive heart failure
                  • Using contrast dye for procedures
                  • Surgery
                  • Alcohol use
                    Detailed Glucophage (Metformin) risks & warnings »
                    Coming soon.
                      • Use of other blood sugar lowering medicines
                      • Alcohol
                      • Intense physical activity
                      • History of sulfa allergies
                      Detailed Glucotrol (Glipizide) risks & warnings »
                      • Heart failure diagnosis
                        • Current liver problems
                          • Female
                          Detailed Actos (Pioglitazone) risks & warnings »
                          Pregnancy

                          Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

                          Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

                          Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

                          Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

                          Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

                          Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

                          Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

                          Interactions
                          NesinaJanuviaByettaMetforminPrecoseGlucotrolActos
                          No interactions related info.No interactions related info.
                          • Because Byetta (Exenatide) can interact with antibiotics and birth control pills, you can't take it until one hour after these medications.
                          No interactions related info.No interactions related info.No interactions related info.No interactions related info.
                          Alcohol
                          NesinaJanuviaByettaMetforminPrecoseGlucotrolActos
                          No alcohol related info.No alcohol related info.No alcohol related info.No alcohol related info.No alcohol related info.
                          • Avoid drinking alcohol.
                          No alcohol related info.
                          Food
                          NesinaJanuviaByettaMetforminPrecoseGlucotrolActos
                          No food related info.No food related info.
                          • Eat regular, balanced meals to avoid low blood sugar.
                          • Always take it with food or switch to the extended release version to avoid upset stomach.
                          No food related info.
                          • Food can cause unpredictable effects of the immediate-release version of Glipizide, so you have to take it at least 30 minutes before a meal.
                          • Eat regular, balanced meals to avoid low blood sugar.
                          No food related info.
                          Kidneys and liver
                          NesinaJanuviaByettaMetforminPrecoseGlucotrolActos
                          No kidneys and liver related info.No kidneys and liver related info.
                          • If you have severe kidney or liver problems, you should not take Byetta (Exenatide). Talk to your doctor about testing your kidneys before starting Byetta (Exenatide). People taking medications that are damaging to kidneys such as ACE inhibitors, NSAIDs or diuretics in addition to Byetta (Exenatide) may notice nausea, vomiting, or diarrhea.
                          • People with poor kidney function can't use it.
                          • Glucophage (Metformin) can cause this rare but life-threatening condition. Symptoms include deep and rapid breathing, nausea, vomiting, and stomach pain. This is a medical emergency and you should get help right away. Baseline blood work for kidney and liver function are helpful to see if you can use Glucophage (Metformin). It may not be a good choice for people with kidney problems. Glucophage (Metformin) should be stopped 48 hours before and/or after surgery or any imaging procedure needing contrast dye.
                          No kidneys and liver related info.
                          • Might be a better choice for people with kidney problems compared to similar drugs because Glipizide isn't processed by the kidneys.
                          No kidneys and liver related info.
                          Pain
                          NesinaJanuviaByettaMetforminPrecoseGlucotrolActos
                          No pain related info.No pain related info.
                          • Using Byetta (Exenatide) has been associated with stomach pain, nausea, vomiting and diarrhea. If you have severe gastrointestinal disease such as Crohn’s Disease or Ulcerative Colitis, you should talk to your doctor about using a different medication for diabetes. You should not use Byetta (Exenatide) if you have gastroparesis, a condition that causes slow or irregular digestion. Gastroparesis can be common for people that have had uncontrolled diabetes for a while.
                          No pain related info.No pain related info.No pain related info.No pain related info.
                          Weight
                          NesinaJanuviaByettaMetforminPrecoseGlucotrolActos
                          No weight related info.
                          • Unlike some diabetes medicines, it's unlikely to cause weight gain and low blood sugar.
                          No weight related info.
                          • Unlike some diabetes medicines, doesn't cause weight gain or low blood sugar.
                          No weight related info.
                          • Can cause mild weight gain (2 to 3 pounds).
                          • Can cause weight gain, dizziness, or stomach upset.
                          • More likely to cause weight gain (2 to 6 pounds or more) compared to other blood sugar-lowering medicines.
                          • Can cause weight gain, headache, and fluid retention.
                          Upsides and benefits
                          NesinaJanuviaByettaMetforminPrecoseGlucotrolActos
                          • Patients taking alogliptin had less cold symptoms than patients taking Januvia.
                          • Oral blood sugar-lowering medicine.
                          • Lowers A1c levels by around 1%. (Hemoglobin A1c measures your average blood sugar over time.)
                          • Prevents the harmful effects of high sugar levels on your organs and blood vessels.
                          • Rarely causes low blood sugar.
                          • Lowers A1c levels by 0.5-0.8%. (Hemoglobin A1c measures your average blood sugar over time.)
                          • Uses the hormones naturally produced by your body to affect how sugar is processed.
                          • Unlike some diabetes medicines, it's unlikely to cause weight gain and low blood sugar.
                          • Oral blood sugar-lowering medicine.
                          • Prevents the harmful effects of high sugar levels on your organs and blood vessels.
                          • You don't have to check your blood sugar every day with this medicine.
                          • Lowers A1c levels by 1% (A1c measures your average blood sugar over time.)
                          • Prevents the harmful effects of high sugar levels on your organs.
                          • Has a lower chance of causing low blood sugar than medications like glyburide or insulin.
                          • Can lower your appetite by making you feel full. Some people also lose weight when taking Byetta (Exenatide).
                          • Byetta (Exenatide) is not a replacement for diabetes pills, but you may be able to use it alone without the need for pills.
                          • The injectable “pen” has easy to use doses which you may find more convenient than other types of injections.
                          • A common first treatment for people with newly-diagnosed Type 2 diabetes.
                          • The only oral diabetes medicine that lowers complications and deaths from conditions related to diabetes.
                          • Also lowers certain lipid (fat and cholesterol) levels.
                          • Unlike some diabetes medicines, doesn't cause weight gain or low blood sugar.
                          • Oral blood sugar-lowering medicine.
                          • Lowers A1c levels by 1-2%. (Hemoglobin A1c measures your average blood sugar over time.)
                          • Prevents the harmful effects of high sugar levels on your organs and blood vessels.
                          • You don't have to check your blood sugar every day with this medicine.
                          • One of the least expensive diabetes medicines.
                          Coming soon
                          • Might be a better choice for people with kidney problems compared to similar drugs because Glipizide isn't processed by the kidneys.
                          • Oral blood sugar-lowering medicine.
                          • Lowers A1c levels by 1-2%. (Hemoglobin A1c measures your average blood sugar over time.)
                          • Prevents the harmful effects of high sugar levels on your organs and blood vessels.
                          • One of the least expensive diabetes medicines.
                          • Oral blood sugar-lowering medicine.
                          • Lowers A1c levels by around 1%. (Hemoglobin A1c measures your average blood sugar over time.)
                          • Prevents the harmful effects of high sugar levels on your organs and blood vessels.
                          • Rarely causes low blood sugar.
                          Downsides and risks
                          NesinaJanuviaByettaMetforminPrecoseGlucotrolActos
                          • Not as strong as other diabetes medicines. Your doctor might add it to your blood sugar-lowering regimen if your sugar levels are still too high.
                          • Likely expensive since there's no generic version available.
                          • Some people might get frequent throat infections or nasal congestion.
                          • Not as strong as other diabetes medicines. Your doctor might add it to your blood sugar-lowering regimen if your sugar levels are still too high.
                          • Likely expensive since there's no generic version available.
                          • Some people might get frequent throat infections or nasal congestion.
                          • Only lowers A1c levels by 1%, which may not be enough to get your blood sugar in the safe range.
                          • Byetta (Exenatide) must be injected twice a day.
                          • Up to 40% of people taking Byetta (Exenatide) have upset stomach and side effects like nausea, vomiting, diarrhea, constipation, or indigestion.
                          • Because Byetta (Exenatide) can interact with antibiotics and birth control pills, you can't take it until one hour after these medications.
                          • Other diabetes medications work as well and are cheaper.
                          • Most people will have nausea, indigestion, or diarrhea in the first few weeks. You can minimize this if you take it on a full stomach.
                          • People with poor kidney function can't use it.
                          • Only works if your body can still make your own insulin, a hormone that tells your body what to do with sugar, protein, and fat.
                          Coming soon
                          • Higher risk of low blood sugar episodes than other kinds of oral diabetes medicines.
                          • You have to check your blood sugar 2 to 5 times a week (less often once you are on a stable dose).
                          • Can cause mild weight gain (2 to 3 pounds).
                          • Loses effectiveness over time or as your body stops making insulin.
                          • Food can cause unpredictable effects of the immediate-release version of Glipizide, so you have to take it at least 30 minutes before a meal.
                          • May take several weeks to lower blood sugar.
                          • You have to check your blood sugar regularly with this medicine.
                          • Has more side effects than similar medicines, so it's usually not the first choice for new Type 2 diabetes patients.
                          • More likely to cause weight gain (2 to 6 pounds or more) compared to other blood sugar-lowering medicines.
                          • Up to 1 in 10 people might get fluid retention (edema), ranging from mild ankle swelling to severe swelling in the lungs that makes it hard to breathe. People with severe congestive heart failure shouldn't use Actos.
                          • Raises the risk of bone fractures, especially for people who already have a risk for fractures.
                          • Slightly raises the risk of bladder cancer.
                          Tips from our pharmacists for people taking the medication
                          NesinaJanuviaByettaMetforminPrecoseGlucotrolActos
                          • Can cause headache and cold-like symptoms.
                          • Tell your doctor about any mental confusion, persistent abdominal pain, dark urine, yellowing of eyes/skin, or easy bruising.
                          • Can be expensive depending on insurance coverage.
                          • Check your blood sugar regularly.
                          • Tell your doctor about persistent stomach pain, nausea, vomiting, or loss of appetite.
                          • Can cause headache and cold-like symptoms.
                          • Can be expensive depending on insurance coverage.
                          • Check your blood sugar regularly.
                          • Store in the refrigerator until opening. Do not freeze.
                          • Give injections in your belly, thighs, or upper arm within an hour of your two main meals of the day (separate doses by 6 or more hours).
                          • Change the needle and prime the pen every time you inject.
                          • It’s not safe to share this medication with other people, even if you change the needle.
                          • Don’t mix with insulin; give separate injections. Can be given at the same time as insulin, but in different injection areas.
                          • It's best to check your blood sugar at least once a day using a home blood sugar monitor to make sure your medication is working and is safe. Some people may need to test more often, ask your doctor.
                          • Eat regular, balanced meals to avoid low blood sugar.
                          • Can cause upset stomach with nausea and especially diarrhea in the first couple of weeks.
                          • Always take it with food or switch to the extended release version to avoid upset stomach.
                          • Tell your doctor about any deep or rapid breathing, or persistent nausea, vomiting, and stomach pain.
                          • Check your blood sugar regularly.
                          Coming soon
                          • Works best if you take it 30 minutes before a meal, usually your first big meal of the day.
                          • Can cause weight gain, dizziness, or stomach upset.
                          • Avoid drinking alcohol.
                          • Eat regular, balanced meals to avoid low blood sugar.
                          • Check your blood sugar regularly.
                          • Takes several weeks to see full effect on blood sugar control.
                          • Can cause weight gain, headache, and fluid retention.
                          • Not recommended for patients with certain heart problems.
                          • Tell your doctor about any mental confusion, persistent abdominal pain, dark urine, yellowing of eyes/skin, or easy bruising.
                          • Check your blood sugar regularly.
                          Learn more
                          More about NesinaSide effectsReviews & ratingsAlternativesFDA package insert
                          Have you used Nesina (Alogliptin)?
                          Worth itNot sureNot worth it
                          More about JanuviaSide effectsReviews & ratingsFDA package insert
                          Have you used Januvia (Sitagliptin)?
                          Worth itNot sureNot worth it
                          More about ByettaSide effectsReviews & ratingsFDA package insert
                          Have you used Byetta (Exenatide)?
                          Worth itNot sureNot worth it
                          More about MetforminSide effectsReviews & ratingsFDA package insert
                          Have you used Glucophage (Metformin)?
                          Worth itNot sureNot worth it
                          More about PrecoseSide effectsReviews & ratingsFDA package insert
                          Have you used Precose (Acarbose)?
                          Worth itNot sureNot worth it
                          More about GlucotrolSide effectsReviews & ratingsFDA package insert
                          Have you used Glucotrol (Glipizide)?
                          Worth itNot sureNot worth it
                          More about ActosSide effectsReviews & ratingsFDA package insert
                          Have you used Actos (Pioglitazone)?
                          Worth itNot sureNot worth it