4.6/ 7 average rating with 620 reviewsforNeurontin

Neurontin
Alternatives

(gabapentin)

Neurontin (gabapentin)

Prescription only

Cymbalta (duloxetine)

Prescription only
1 of 7 alternatives
Treats tingling and burning nerve pain.

Neurontin (gabapentin) is an old seizure disorder medicine that is now used to treat nerve-related pain caused by different conditions.

Improves mood and relieves certain types of pain.

Cymbalta (duloxetine) is good for treating depression, anxiety, and some forms of chronic pain, but it is more likely than other antidepressants to cause problems if you drink alcohol or have high blood pressure.

Upsides
  • Originally used to treat epilepsy (partial seizures), but now it primarily treats neuropathic pain that's caused by nerve stimulation or damage.
  • Studies show it's most effective for nerve pain from diabetes, shingles, and fibromyalgia (a painful muscle condition).
  • It's available as a generic, so it's less expensive than similar medications.
  • Cymbalta (duloxetine) may help relieve nerve pain from diabetes and other forms of chronic pain.
  • Cymbalta (duloxetine) has several uses, which may be good for people with multiple conditions.
  • Available as a generic, which is cheaper.
Downsides
  • Neurontin (gabapentin) can cause some side effects, including memory problems, drowsiness, dizziness, or confusion. There is a higher risk for these side effects if you drink alcohol, so it might not be the best medication for heavy drinkers.
  • You can't skip or miss doses since suddenly stopping Neurontin (gabapentin) can cause seizures.
  • Cymbalta (duloxetine) may not be a good option if you're a heavy drinker, or have liver or kidney problems.
  • Cymbalta (duloxetine) can increase high blood pressure.
  • Like most antidepressants, Cymbalta (duloxetine) can cause higher risk of suicidal thoughts and behavior for people aged 24 and younger.
Used for
Dosage forms
  • Pill
  • Oral solution
  • Extended release
  • Pill
  • Extended release
Price
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Reviews
620 
57%
think this treatment is worth it
40%
think this treatment works well
19%
think this treatment is a hassle

Have you used Neurontin (gabapentin)?

Leave a review
496 
58%
think this treatment is worth it
49%
think this treatment works well
24%
think this treatment is a hassle

Have you used Cymbalta (duloxetine)?

Leave a review
Side effects
The Neurontin (gabapentin) FDA package insert doesn’t have numbers about how common side effects are.
10possible side effects
  • Nausea
    23%
  • Headache
    14%
  • Dry mouth
    13%
  • Drowsiness
    10%
  • Fatigue
    9%
  • Difficulty sleeping
    9%
  • Constipation
    9%
  • Dizziness
    9%
  • Diarrhea
    9%
  • Decreased appetite
    7%
See more detailed side effects
Risks and warnings
  • Neurologic and psychiatric side effects (children)

    Children ages 3 to 12

  • Driving impairment

    Taking Neurontin (gabapentin) with alcohol

    ...and 1 more risk factors

  • Withdrawal seizures

    Stopping Neurontin (gabapentin) suddenly

See more detailed risks and warnings
  • Suicidal thoughts or behavior

    Age 24 years or younger

  • Serotonin syndrome

    Taking tricyclic antidepressants, lithium, tramadol, fentanyl, amphetamines, certain headache medications (triptans), St. John's Wort

  • Withdrawal

    Stopping Cymbalta (duloxetine) abruptly

  • Increased bleeding

    Taking other blood-thinning drugs (including aspirin, NSAIDs such as Advil, warfarin)

  • Changes in blood pressure and risk of falls

    Elderly patients

    ...and 4 more risk factors

  • Bipolar disorder

    History of bipolar disorder

    ...and 1 more risk factors

See more detailed risks and warnings