Prescription or OTCLower-cost generic available

Nexium Alternatives

(Esomeprazole)

Prescription or OTCLower-cost generic available
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Compare Nexium (Esomeprazole) to alternatives

These medications are comparable to Nexium (Esomeprazole) or used for similar purposes.

Nexium
(Esomeprazole)

Alka-Seltzer Original
(Aspirin / Citric Acid / Sodium Bicarbonate)

Pepcid
(Famotidine)

Zegerid
(Omeprazole / Sodium Bicarbonate)

Rolaids
(Calcium Carbonate / Magnesium Hydroxide)

Prilosec
(Omeprazole)

Tums
(Calcium Carbonate)

Maalox
(Aluminum / Magnesium / Simethicone)

Zantac 75
(Ranitidine)

Tagamet
(Cimetidine)

Protonix
(Pantoprazole)

Treats heartburn and stomach ulcers. Nexium (Esomeprazole) gives you long-lasting heartburn relief. But this purple pill ain't cheap! The generic forms of alternative drugs work just as well, and are usually less expensive.Relieves heartburn, headache, and body pains. Alka-Seltzer Original (Aspirin / Citric Acid / Sodium Bicarbonate) gives quick relief for headache, body pains, and upset tummies, but might be hard to swallow if you don't like the taste or fizz.Relieves heartburn. Pepcid (Famotidine) works well for heartburn but may not last as long or start working as quickly as other antacids.Relieves heartburn, ulcers, and acid tummy. Zegerid (Omeprazole / Sodium Bicarbonate) gives you long-lasting heartburn relief. Choose the cheapest proton pump inhibitor because they all work equally well for heartburn.Relieves heartburn and acid tummy. Rolaids (Calcium Carbonate / Magnesium Hydroxide) gives quick relief for heartburn, but don't expect it to last all day.Treats heartburn and stomach ulcers. Prilosec (Omeprazole) gives you long-lasting heartburn relief. Choose the cheapest proton pump inhibitor because they all work equally well for heartburn.Relieves heartburn. Tums (Calcium Carbonate) gives quick relief for heartburn, but don't expect it to last all day.Relieves heartburn and acid tummy. Maalox (Aluminum / Magnesium / Simethicone) gives quick relief for heartburn, gas, and bloating. It may not be as effective or last as long as alternative antacids though.Relieves heartburn. Zantac 75 (Ranitidine) works well for heartburn but may not last as long or start working as quickly as other antacids.Relieves heartburn and acid tummy. Tagamet (Cimetidine) works well for heartburn but may not last as long or start working as quickly as other antacids.Treats heartburn and stomach ulcers. Protonix (Pantoprazole) gives you long-lasting heartburn relief. Choose the cheapest proton pump inhibitor because they all work equally well for heartburn.
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Reviews & ratings
Filter group. All currently selected
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5.442903752039152Nexium
Reviews for Nexium (Esomeprazole)
75%
of people (All ages) say Nexium (Esomeprazole) is worth it
59%
say it works well
11%
say it's a big hassle
1226 reviews
Have you used Nexium (Esomeprazole)?
Worth itNot sureNot worth it
Reviews for Alka-Seltzer Original (Aspirin / Citric Acid / Sodium Bicarbonate)
81%
+6% vs. Nexium (Esomeprazole)
52%
7% vs. Nexium (Esomeprazole)
8%
+3% vs. Nexium (Esomeprazole)
1053 reviews
Have you used Alka-Seltzer Original (Aspirin / Citric Acid / Sodium Bicarbonate)?
Worth itNot sureNot worth it
Reviews for Pepcid (Famotidine)
75%
Same vs. Nexium (Esomeprazole)
41%
18% vs. Nexium (Esomeprazole)
8%
+3% vs. Nexium (Esomeprazole)
848 reviews
Have you used Pepcid (Famotidine)?
Worth itNot sureNot worth it
Reviews for Zegerid (Omeprazole / Sodium Bicarbonate)
71%
4% vs. Nexium (Esomeprazole)
54%
5% vs. Nexium (Esomeprazole)
13%
2% vs. Nexium (Esomeprazole)
Have you used Zegerid (Omeprazole / Sodium Bicarbonate)?
Worth itNot sureNot worth it
Reviews for Rolaids (Calcium Carbonate / Magnesium Hydroxide)
75%
Same vs. Nexium (Esomeprazole)
37%
22% vs. Nexium (Esomeprazole)
7%
+4% vs. Nexium (Esomeprazole)
1087 reviews
Have you used Rolaids (Calcium Carbonate / Magnesium Hydroxide)?
Worth itNot sureNot worth it
Reviews for Prilosec (Omeprazole)
80%
+5% vs. Nexium (Esomeprazole)
59%
Same vs. Nexium (Esomeprazole)
7%
+4% vs. Nexium (Esomeprazole)
1142 reviews
Have you used Prilosec (Omeprazole)?
Worth itNot sureNot worth it
Reviews for Tums (Calcium Carbonate)
82%
+7% vs. Nexium (Esomeprazole)
43%
16% vs. Nexium (Esomeprazole)
5%
+6% vs. Nexium (Esomeprazole)
1370 reviews
Have you used Tums (Calcium Carbonate)?
Worth itNot sureNot worth it
Reviews for Maalox (Aluminum / Magnesium / Simethicone)
68%
7% vs. Nexium (Esomeprazole)
30%
29% vs. Nexium (Esomeprazole)
9%
+2% vs. Nexium (Esomeprazole)
212 reviews
Have you used Maalox (Aluminum / Magnesium / Simethicone)?
Worth itNot sureNot worth it
Reviews for Zantac 75 (Ranitidine)
72%
3% vs. Nexium (Esomeprazole)
43%
16% vs. Nexium (Esomeprazole)
7%
+4% vs. Nexium (Esomeprazole)
1049 reviews
Have you used Zantac 75 (Ranitidine)?
Worth itNot sureNot worth it
Reviews for Tagamet (Cimetidine)
63%
12% vs. Nexium (Esomeprazole)
36%
23% vs. Nexium (Esomeprazole)
12%
1% vs. Nexium (Esomeprazole)
631 reviews
Have you used Tagamet (Cimetidine)?
Worth itNot sureNot worth it
Reviews for Protonix (Pantoprazole)
69%
6% vs. Nexium (Esomeprazole)
51%
8% vs. Nexium (Esomeprazole)
13%
2% vs. Nexium (Esomeprazole)
551 reviews
Have you used Protonix (Pantoprazole)?
Worth itNot sureNot worth it
Side effects
NexiumAlka-SeltzerPepcidZegeridRolaidsOmeprazoleTumsMaaloxZantacTagametPantoprazole

The Nexium FDA package insert doesn’t have numbers about how common side effects are.

More about Nexium side effects »

We haven’t found good data for Alka-Seltzer side effects.

FDA side effect reports for Alka-Seltzer »

The Pepcid FDA package insert doesn’t have numbers about how common side effects are.

More about Pepcid side effects »

The Zegerid FDA package insert doesn’t have numbers about how common side effects are.

More about Zegerid side effects »

We haven’t found good data for Rolaids side effects.

FDA side effect reports for Rolaids »

The Omeprazole FDA package insert doesn’t have numbers about how common side effects are.

More about Omeprazole side effects »

We haven’t found good data for Tums side effects.

FDA side effect reports for Tums »

We haven’t found good data for Maalox side effects.

FDA side effect reports for Maalox »

The Zantac FDA package insert doesn’t have numbers about how common side effects are.

More about Zantac side effects »
  • Headache 2%
More Tagamet side effects »

We haven’t found good data for Pantoprazole side effects.

FDA side effect reports for Pantoprazole »
How it works
NexiumAlka-SeltzerPepcidZegeridRolaidsOmeprazoleTumsMaaloxZantacTagametPantoprazole
Nexium (Esomeprazole) is a proton pump inhibitor (PPI). It lowers the amount of acid in your stomach, treats heartburn, and heals ulcers.Alka-Seltzer Original (Aspirin / Citric Acid / Sodium Bicarbonate) is a combination medicine. Sodium bicarbonate is an antacid that relieves heartburn and acid tummy (indigestion). Aspirin is a pain reliever that treats headache and body pains.Pepcid (Famotidine) is a type of antacid called an H2 blocker. It blocks the chemical histamine, which lowers acid production in your stomach. This treats heartburn and helps ulcers heal.Zegerid (Omeprazole / Sodium Bicarbonate) is a type of antacid called a proton pump inhibitor. It blocks the release of acid in your stomach, which treats heartburn and helps ulcers heal.Rolaids (Calcium Carbonate / Magnesium Hydroxide) is an antacid. It counteracts the effects of stomach acid to relieve heartburn and acid tummy (indigestion).Prilosec (Omeprazole) is a proton pump inhibitor (PPI). It lowers the amount of acid in your stomach, treats heartburn, and heals ulcers.Tums (Calcium Carbonate) is an antacid. It counteracts the effects of stomach acid to relieve heartburn and acid tummy (indigestion).Maalox (Aluminum / Magnesium / Simethicone) is a combination medicine for stomach trouble. Aluminum and magnesium are antacids that relieve heartburn and acid tummy (indigestion). Simethicone relieves gas and bloating.Zantac 75 (Ranitidine) is an H2 blocker. It blocks the chemical histamine, which lowers acid production in your stomach. This treats heartburn and helps ulcers heal.Tagamet (Cimetidine) is a type of antacid called an H2 blocker. It blocks the chemical histamine, which lowers acid production in your stomach. This treats heartburn and helps ulcers heal.Protonix (Pantoprazole) is a proton pump inhibitor (PPI). It lowers the amount of acid in your stomach, treats heartburn, and heals ulcers.
Type of medication
NexiumAlka-SeltzerPepcidZegeridRolaidsOmeprazoleTumsMaaloxZantacTagametPantoprazole
Acid reducer
Proton pump inhibitor
Prescription or OTC
AntacidOver-the-counter
Acid reducer
Histamine blocker
Prescription or OTC
Acid reducer
Proton pump inhibitor
Antacid
Prescription or OTC
AntacidOver-the-counter
Acid reducer
Proton pump inhibitor
Prescription or OTC
AntacidOver-the-counter
AntacidOver-the-counter
Acid reducer
Histamine blocker
Prescription or OTC
Acid reducer
Histamine blocker
Prescription or OTC
Acid reducer
Proton pump inhibitor
Prescription only
Available as
NexiumAlka-SeltzerPepcidZegeridRolaidsOmeprazoleTumsMaaloxZantacTagametPantoprazole
  • Extended release
  • Chewable tablet
  • Effervescent tablet
  • Pill
  • Chewable tablet
  • Liquid
  • Pill
  • Chewable tablet
  • Liquid
  • Extended release
  • Chewable tablet
  • Liquid
  • Chewable tablet
  • Liquid
  • Pill
  • Oral solution
  • Injection
  • Pill
  • Liquid
  • Extended release
Used for (click to learn more)
NexiumAlka-SeltzerPepcidZegeridRolaidsOmeprazoleTumsMaaloxZantacTagametPantoprazole
Risk factors for serious side effects
NexiumAlka-SeltzerPepcidZegeridRolaidsOmeprazoleTumsMaaloxZantacTagametPantoprazole
    • Helicobacter pylori infection
    • Autoimmune disease
    • Being hospitalized
    • Antibiotic use
    • Osteoporosis
    • Age 50 or older
    • Using high medication doses
    • Long-term therapy (1 year or more)
    • Smoking
    • Use of other medications that weaken bones
      Detailed Nexium (Esomeprazole) risks & warnings »
        • Current kidney disease
        • Kidney dialysis
        • Age 65 or older
        • Congestive heart failure (CHF)
        • High blood pressure
        • Current kidney disease
        • Kidney dialysis
        • Children 18 years or younger recovering from viral infections
        • History of stomach bleeding or ulcers
        • Age 60 or older
        • Also taking other blood thinners
        • Drinking 3 or more alcoholic drinks a day
        • Asthma
        • Rhinitis
        • Nasal Polyps
        • Aspirin Allergy
        • NSAID Allergy
          Detailed Alka-Seltzer Original (Aspirin / Citric Acid / Sodium Bicarbonate) risks & warnings »
            • Current kidney disease
              Detailed Pepcid (Famotidine) risks & warnings »
                • Helicobacter pylori infection
                • Autoimmune disease
                • Being hospitalized
                • Antibiotic use
                • Osteoporosis
                • Age 50 or older
                • Using high medication doses
                • Long-term therapy (1 year or more)
                • Smoking
                • Use of other medications that weaken bones
                  • Stroke
                  • Coronary artery stent
                  • Taking Clopidogrel
                  • Rheumatoid arthritis
                  • Psoriasis
                  • Cancer
                  • Taking methotrexate
                    Detailed Zegerid (Omeprazole / Sodium Bicarbonate) risks & warnings »
                      • Current kidney disease
                      • Kidney dialysis
                      • Hyperparathyroid disease
                      • Taking high doses of Vitamin D
                      • Previous kidney stones
                      Detailed Rolaids (Calcium Carbonate / Magnesium Hydroxide) risks & warnings »
                        • Helicobacter pylori infection
                        • Autoimmune disease
                        • Being hospitalized
                        • Antibiotic use
                        • Osteoporosis
                        • Age 50 or older
                        • Using high medication doses
                        • Long-term therapy (1 year or more)
                        • Smoking
                        • Use of other medications that weaken bones
                          Detailed Prilosec (Omeprazole) risks & warnings »
                            • Current kidney disease
                            • Kidney dialysis
                            • Hyperparathyroid disease
                            • Taking high doses of Vitamin D
                            • Previous kidney stones
                            Detailed Tums (Calcium Carbonate) risks & warnings »
                            • Age 65 or older
                              • Current kidney disease
                                Detailed Maalox (Aluminum / Magnesium / Simethicone) risks & warnings »
                                  • Current kidney problems
                                  • Current liver problems
                                  • Acute Porphyria
                                  • History of Phenylketonuria (PKU)
                                  Detailed Zantac 75 (Ranitidine) risks & warnings »
                                    • Current kidney disease
                                    • Current liver disease
                                    • Age 50 or older
                                    • Current severe illness
                                      • Autoimmune disease
                                      • HIV or AIDS
                                      • Organ transplant
                                      • People without a spleen
                                      Detailed Tagamet (Cimetidine) risks & warnings »
                                        • Helicobacter pylori infection
                                        • Autoimmune disease
                                        • Osteoporosis
                                        • Age 50 or older
                                        • Using high medication doses
                                        • Long-term therapy (1 year or more)
                                        • Smoking
                                        • Use of other medications that weaken bones
                                            Detailed Protonix (Pantoprazole) risks & warnings »
                                            Pregnancy

                                            Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

                                            The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

                                            Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

                                            Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

                                            The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

                                            Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

                                            The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

                                            The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

                                            Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

                                            Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

                                            Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

                                            Interactions
                                            NexiumAlka-SeltzerPepcidZegeridRolaidsOmeprazoleTumsMaaloxZantacTagametPantoprazole
                                            • Can interact with other drugs so be sure your doctor knows all the medicine you're taking before starting Nexium.
                                            • Avoid drug interactions by telling your doctor all of the other medications or herbal supplements you take before starting Nexium.
                                            No interactions related info.
                                            • Few drug interactions.
                                            • Can interact with other drugs so be sure your doctor knows all the medicine you're taking before starting Zegerid.
                                            • Avoid drug interactions by telling your doctor all of the other medications or herbal supplements you take before starting Zegerid.
                                            No interactions related info.
                                            • Can interact with other drugs so be sure your doctor knows all the medicine you're taking before starting Omeprazole.
                                            • Avoid drug interactions by telling your doctor all of the other medications or herbal supplements you take before starting Omeprazole.
                                            • You need to separate Tums from some medications to avoid interactions.
                                            No interactions related info.
                                            • Few drug interactions.
                                            • Has more drug interactions than zantac and pepcid.
                                            • Less risk of drug interactions with Pantoprazole than with other proton pump inhibitors.
                                            • Avoid drug interactions by telling your doctor all of the other medications or herbal supplements you take before starting Pantoprazole.
                                            Food
                                            NexiumAlka-SeltzerPepcidZegeridRolaidsOmeprazoleTumsMaaloxZantacTagametPantoprazole
                                            • Take 1 hour before a meal.
                                            • Take it with food to lower the chance of an upset stomach.
                                            No food related info.
                                            • Take 1 hour before a meal.
                                            No food related info.
                                            • Take 1 hour before a meal.
                                            No food related info.
                                            • Take 1-3 hours after a meal.
                                            No food related info.No food related info.
                                            • Take with or without food.
                                            Kidneys and liver
                                            NexiumAlka-SeltzerPepcidZegeridRolaidsOmeprazoleTumsMaaloxZantacTagametPantoprazole
                                            No kidneys and liver related info.
                                            • If you have kidney or hyperparathyroid disease Alka-Seltzer Original (Aspirin / Citric Acid / Sodium Bicarbonate) can build up in your blood. This may can cause toxic levels of sodium in your body. This is more likely if you have severe kidney disease (defined as a kidney function blood test called GFR of less than 30ml/min). If you have severe kidney disease or are on kidney dialysis don't use Alka-Seltzer Original (Aspirin / Citric Acid / Sodium Bicarbonate); a different antacid would be better for you.
                                            • Can cause more serious side effects for people with kidney disease. Ask your doctor to give you a lower dose or choose a different option.
                                            • Because Pepcid (Famotidine) is processed by the kidney it can cause some worrisome side effects for people with kidney problems. These include confusion, delirium, and a dangerous irregular heartbeat known as QT prolongation. If you have kidney problems, you may need a different dose to prevent this increased risk for side effects.
                                            No kidneys and liver related info.
                                            • People with kidney disease on dialysis may need to take a lower dose or avoid use. Your doctor can do blood tests to see if it's safe to use.
                                            • If you have kidney or hyperparathyroid disease Rolaids (Calcium Carbonate / Magnesium Hydroxide) can build up in your blood. This may can cause toxic levels of calcium in your body. This is more likely if you have severe kidney disease (defined as a kidney function blood test called GFR of less than 30ml/min). If you have severe kidney disease or are on kidney dialysis don't use Rolaids (Calcium Carbonate / Magnesium Hydroxide); a different antacid would be better for you.
                                            • Rolaids (Calcium Carbonate / Magnesium Hydroxide) contains calcium. Calcium can be an ingredient in some kidney stones. If you have had kidney stones in the past (especially the calcium-containing kind) be careful using Rolaids (Calcium Carbonate / Magnesium Hydroxide). Use the lowest dose for the shortest time possible or just play it safe and use a different antacid instead.
                                            No kidneys and liver related info.
                                            • People with kidney disease on dialysis may need to take a lower dose or avoid use. Your doctor can do blood tests to see if it's safe to use.
                                            • If you have kidney or hyperparathyroid disease Tums (Calcium Carbonate) can build up in your blood. This may can cause toxic levels of calcium in your body. This is more likely if you have severe kidney disease (defined as a kidney function blood test called GFR of less than 30ml/min). If you have severe kidney disease or are on kidney dialysis don't use Tums (Calcium Carbonate); a different antacid would be better for you.
                                            • Tums (Calcium Carbonate) contains calcium. Calcium can be an ingredient in some kidney stones. If you have had kidney stones in the past (especially the calcium-containing kind) be careful using Tums (Calcium Carbonate). Use the lowest dose for the shortest time possible or just play it safe and use a different antacid instead.
                                            • People with kidney disease may need to avoid Maalox. Ask your doctor.
                                            • If you have kidney disease Maalox (Aluminum / Magnesium / Simethicone) can build up in your blood. This may can cause toxic levels of aluminum or magnesium in your body. This is more likely if you have severe kidney disease (defined as a kidney function blood test called GFR of less than 30ml/min). If you have severe kidney disease or are on kidney dialysis don't use Maalox (Aluminum / Magnesium / Simethicone); a different antacid would be better for you.
                                            • People with kidney disease may need to take a lower dose.
                                            • Zantac 75 (Ranitidine) is processed by the kidney and liver. If you have kidney or liver problems, you may need a different dose to prevent this increased risk for side effects.
                                            • People with kidney disease may need to take a lower dose.
                                            No kidneys and liver related info.
                                            Upsides and benefits
                                            NexiumAlka-SeltzerPepcidZegeridRolaidsOmeprazoleTumsMaaloxZantacTagametPantoprazole
                                            • Most people can take Nexium without any noticeable day-to-day side effects.
                                            • Nexium lasts longer than other types of antacids (like Zantac, Pepcid, or Tums), and you only need to take it once or twice a day.
                                            • In studies it was better than a placebo (sugar pill) and as good as other proton pump inhibitors at treating heartburn.
                                            • Works great if you have an upset stomach and a headache or body pain at the same time.
                                            • Works really fast.
                                            • Available over the counter without a prescription.
                                            • Cheap.
                                            • Most people can take Famotidine without any noticeable day-to-day side effects.
                                            • Famotidine lasts longer than many other antacids like Maalox and Tums, and you only need to take it once or twice a day.
                                            • Few drug interactions.
                                            • Most people can take Zegerid without any noticeable day-to-day side effects.
                                            • Zegerid lasts longer than other types of antacids (like Zantac, Pepcid, or Tums), and you only need to take it once or twice a day.
                                            • In studies it was better than a placebo (sugar pill) and as good as other proton pump inhibitors at treating heartburn.
                                            • Works really fast.
                                            • Available over the counter without a prescription.
                                            • Cheap.
                                            • Most people can take Omeprazole without any noticeable day-to-day side effects.
                                            • Omeprazole lasts longer than other types of antacids (like Zantac, Pepcid, or Tums), and you only need to take it once or twice a day.
                                            • In studies it was better than a placebo (sugar pill) and as good as other proton pump inhibitors at treating heartburn.
                                            • Works really fast.
                                            • Available over the counter without a prescription.
                                            • Cheap.
                                            • Works really fast.
                                            • Available over the counter without a prescription.
                                            • Cheap.
                                            • Most people can take Ranitidine without any noticeable day-to-day side effects.
                                            • Ranitidine lasts longer than many other antacids like Maalox and Tums, and you only need to take it once or twice a day.
                                            • Few drug interactions.
                                            • Most people can take Cimetidine without any noticeable day-to-day side effects.
                                            • Cimetidine lasts longer than many other antacids like Maalox and Tums, and you only need to take it once or twice a day.
                                            • Most people can take Pantoprazole without any noticeable day-to-day side effects.
                                            • Pantoprazole lasts longer than other types of antacids (like Zantac, Pepcid, or Tums), and you only need to take it once or twice a day.
                                            • In studies it was better than a placebo (sugar pill) and as good as other proton pump inhibitors at treating heartburn.
                                            Downsides and risks
                                            NexiumAlka-SeltzerPepcidZegeridRolaidsOmeprazoleTumsMaaloxZantacTagametPantoprazole
                                            • Can cause low levels of magnesium in the blood. You might need to take a magnesium supplement if you use Nexium long-term.
                                            • Can be expensive—especially the purple brand-name pill. Other alternatives are usually cheaper than Nexium and work just as well.
                                            • Can interact with other drugs so be sure your doctor knows all the medicine you're taking before starting Nexium.
                                            • Doesn't start working as fast as some other antacids like Tums, Rolaids, or Maalox.
                                            • Like with other proton pump inhibitors, long-term use can cause weak or broken bones.
                                            • Because it has aspirin in it, it increases the risk of bleeding, especially if you take any other blood thinning medicine.
                                            • Can't be used by people with allergy to aspirin.
                                            • You may not like the taste or fizz.
                                            • Doesn't last very long.
                                            • Other antacids like Zantac (H2 blockers) and omeprazole (proton pump inhibitors) can work better and last longer.
                                            • Other antacids like Maalox, Tums, or Rolaids often start to work more quickly than Famotidine.
                                            • Medication like omeprazole (proton pump inhibitors) works better at healing and preventing stomach ulcers than medication like Famotidine (H2 blockers).
                                            • Can cause more serious side effects for people with kidney disease. Ask your doctor to give you a lower dose or choose a different option.
                                            • Can cause low levels of magnesium in the blood. You might need to take a magnesium supplement if you use Zegerid long-term.
                                            • Although the generic is affordable, other medications might still be cheaper than Zegerid.
                                            • Can interact with other drugs so be sure your doctor knows all the medicine you're taking before starting Zegerid.
                                            • Doesn't start working as fast as some other antacids like Tums, Rolaids, or Maalox.
                                            • Like with other proton pump inhibitors, long-term use can cause weak or broken bones.
                                            • Doesn't last very long.
                                            • Other antacids like Zantac (H2 blockers) and omeprazole (proton pump inhibitors) can work better and last longer.
                                            • Some chalky aftertaste.
                                            • Can cause low levels of magnesium in the blood. You might need to take a magnesium supplement if you use Omeprazole long-term.
                                            • Although the generic is affordable, other medications might still be cheaper than Omeprazole.
                                            • Can interact with other drugs so be sure your doctor knows all the medicine you're taking before starting Omeprazole.
                                            • Doesn't start working as fast as some other antacids like Tums, Rolaids, or Maalox.
                                            • Like with other proton pump inhibitors, long-term use can cause weak or broken bones.
                                            • Doesn't last very long.
                                            • Other antacids like Zantac (H2 blockers) and omeprazole (proton pump inhibitors) can work better and last longer.
                                            • Some chalky aftertaste.
                                            • Some people don't care for the taste.
                                            • Doesn't last very long.
                                            • Other antacids like Zantac (H2 blockers) and omeprazole (proton pump inhibitors) can work better and last longer.
                                            • Other antacids like Maalox, Tums, or Rolaids often start to work more quickly than Ranitidine.
                                            • Medication like omeprazole (proton pump inhibitors) works better at healing and preventing stomach ulcers than medication like Ranitidine (H2 blockers).
                                            • Other antacids like Maalox, Tums, or Rolaids often start to work more quickly than Cimetidine.
                                            • Medication like omeprazole (proton pump inhibitors) works better at healing and preventing stomach ulcers than medication like Cimetidine (H2 blockers).
                                            • Has more drug interactions than zantac and pepcid.
                                            • Although rare, Cimetidine can cause large breasts or impotence for men who need to use high doses for 6 months or more. It's reversible though and should go away when you stop or if you change medication.
                                            • Can cause low levels of magnesium in the blood. You might need to take a magnesium supplement if you use Pantoprazole long-term.
                                            • Can be expensive. Other alternatives are usually cheaper than Pantoprazole.
                                            • Less risk of drug interactions with Pantoprazole than with other proton pump inhibitors.
                                            • Doesn't start working as fast as some other antacids like Tums, Rolaids, or Maalox.
                                            • Like with other proton pump inhibitors, long-term use can cause weak or broken bones.
                                            Tips from our pharmacists for people taking the medication
                                            NexiumAlka-SeltzerPepcidZegeridRolaidsOmeprazoleTumsMaaloxZantacTagametPantoprazole
                                            • When using Nexium long-term, take a calcium citrate with vitamin D supplement daily to prevent bone loss. Be sure it's calcium citrate because it works the best when using a proton pump inhibitor.
                                            • Get a blood test for your magnesium level once a year; you may need a magnesium supplement while using Nexium.
                                            • Avoid drug interactions by telling your doctor all of the other medications or herbal supplements you take before starting Nexium.
                                            • Take 1 hour before a meal.
                                            • Don't chew or crush capsules; swallow them whole.
                                            • If you have trouble swallowing you can carefully open the capsules and sprinkle the inside pellets onto applesauce. Swallow the applesauce without chewing or crushing the pellets.
                                            • Don't take Alka-Seltzer if you're allergic to aspirin.
                                            • Take it with food to lower the chance of an upset stomach.
                                            • This medicine isn't recommended for kids 12 and younger because it has aspirin in it.
                                            • Stop taking this right away and talk to your doctor if you have ringing in your ears, rash, trouble breathing, unusual bleeding, or nausea or vomiting that doesn't go away.
                                            • Having a dental or medical procedure? You may need to stop taking this before the big day. Ask your dentist or doctor.
                                            • Alka-Seltzer contains sodium. If you need to follow a low sodium diet a different medication would be better for you.
                                            • Not a good choice if you have stomach bleeding, bleeding problems, diabetes, or gout, or if you're taking medicines to thin your blood.
                                            • Short-term treatment of ulcers and acid reflux.
                                            • Avoid drug interactions by telling your doctor all of the other medications or herbal supplements you take before starting Zegerid.
                                            • If you've been having heartburn for 3 months or more, talk to your doctor before taking Zegerid. Get a check-up to make sure you aren't having a more serious stomach problem.
                                            • Talk to your doctor if you're still having heartburn after two weeks of use. Don't keep taking Zegerid; get checked-out first.
                                            • Take 1 hour before a meal.
                                            • Don't chew or crush capsules; swallow them whole.
                                            • Take at the first sign of discomfort.
                                            • You might need to take more than once a day but pay attention to the instructions on your bottle to avoid overdosing.
                                            • Take 1-2 hours apart from other medication that you take by mouth.
                                            • If heartburn doesn't improve or lasts more than 2 weeks, talk to your doctor.
                                            • People with kidney disease on dialysis may need to take a lower dose or avoid use. Your doctor can do blood tests to see if it's safe to use.
                                            • Don't take if you have high blood calcium levels.
                                            • When using Omeprazole long-term, take a calcium citrate with vitamin D supplement daily to prevent bone loss. Be sure it's calcium citrate because it works the best when using a proton pump inhibitor.
                                            • Get a blood test for your magnesium level once a year; you may need a magnesium supplement while using Omeprazole.
                                            • Avoid drug interactions by telling your doctor all of the other medications or herbal supplements you take before starting Omeprazole.
                                            • Take 1 hour before a meal.
                                            • Don't chew or crush capsules; swallow them whole.
                                            • If you have trouble swallowing you can carefully open the capsules and sprinkle the inside pellets onto applesauce. Swallow the applesauce without chewing or crushing the pellets.
                                            • You need to separate Tums from some medications to avoid interactions.
                                            • Take at the first sign of discomfort.
                                            • You might need to take more than once a day but pay attention to the instructions on your bottle to avoid overdosing.
                                            • If heartburn doesn't improve or lasts more than 2 weeks, talk to your doctor.
                                            • People with kidney disease on dialysis may need to take a lower dose or avoid use. Your doctor can do blood tests to see if it's safe to use.
                                            • Don't take if you have high blood calcium levels.
                                            • Take 1-3 hours after a meal.
                                            • Tell your doctor if you have severe diarrhea or constipation.
                                            • People with kidney disease may need to avoid Maalox. Ask your doctor.
                                            • Take 1-2 hours apart from other medication that you take by mouth.
                                            • Works best if you take it with a full glass of water.
                                            • Starts working in one hour.
                                            • If heartburn doesn't improve or lasts more than 2 weeks, talk to your doctor.
                                            • People with kidney disease may need to take a lower dose.
                                            • Tell your doctor all of the medications that you use before taking Cimetidine to avoid drug interactions.
                                            • Works best if you take it with a full glass of water.
                                            • Starts working in one hour.
                                            • If heartburn doesn't improve or lasts more than 2 weeks, talk to your doctor.
                                            • People with kidney disease may need to take a lower dose.
                                            • Take with or without food.
                                            • Swallow tablets whole; don't split, crush, or chew.
                                            • Take the oral suspension 30 minutes before a meal mixed only with applesauce or apple juice. Follow instructions carefully.
                                            • When using Pantoprazole long-term, take a calcium citrate with vitamin D supplement daily to prevent bone loss. Be sure it's calcium citrate because it works the best when using a proton pump inhibitor.
                                            • Get a blood test for your magnesium level once a year; you may need a magnesium supplement while using Pantoprazole.
                                            • Avoid drug interactions by telling your doctor all of the other medications or herbal supplements you take before starting Pantoprazole.
                                            Learn more
                                            More about NexiumSide effectsReviews & ratingsAlternativesFDA package insert
                                            Have you used Nexium (Esomeprazole)?
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                                            More about Alka-SeltzerSide effectsReviews & ratingsFDA package insert
                                            Have you used Alka-Seltzer Original (Aspirin / Citric Acid / Sodium Bicarbonate)?
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                                            More about PepcidSide effectsReviews & ratingsFDA package insert
                                            Have you used Pepcid (Famotidine)?
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                                            More about ZegeridSide effectsReviews & ratingsFDA package insert
                                            Have you used Zegerid (Omeprazole / Sodium Bicarbonate)?
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                                            More about RolaidsSide effectsReviews & ratingsFDA package insert
                                            Have you used Rolaids (Calcium Carbonate / Magnesium Hydroxide)?
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                                            More about OmeprazoleSide effectsReviews & ratingsFDA package insert
                                            Have you used Prilosec (Omeprazole)?
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                                            More about TumsSide effectsReviews & ratingsFDA package insert
                                            Have you used Tums (Calcium Carbonate)?
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                                            More about MaaloxSide effectsReviews & ratingsFDA package insert
                                            Have you used Maalox (Aluminum / Magnesium / Simethicone)?
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                                            More about ZantacSide effectsReviews & ratingsFDA package insert
                                            Have you used Zantac 75 (Ranitidine)?
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                                            More about TagametSide effectsReviews & ratingsFDA package insert
                                            Have you used Tagamet (Cimetidine)?
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                                            More about PantoprazoleSide effectsReviews & ratingsFDA package insert
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