Prescription onlyLower-cost generic availableClass: Cardiovascular

NiaspanAlternatives

(niacin)

Prescription onlyLower-cost generic availableClass: Cardiovascular
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Compare Niaspan (niacin) to alternatives

These medications are comparable to Niaspan (niacin) or used for similar purposes.

Niaspan
(niacin)

Zetia
(ezetimibe)

Pravachol
(pravastatin)

Mevacor
(lovastatin)

Lovaza
(omega-3 acid)

Antara
(fenofibrate)

Trilipix
(fenofibric acid)

Vytorin
(ezetimibe / simvastatin)

Lipitor
(atorvastatin)

Crestor
(rosuvastatin)

Zocor
(simvastatin)

Lowers cholesterol. Niaspan (Niacin) lowers triglycerides, but isn't as good as statins for improving cholesterol levels.Lowers cholesterol. Zetia (ezetimibe) can improve your cholesterol and can be used as an alternative to statins.Lowers cholesterol. Pravachol (pravastatin) can improve cholesterol, but it's not as strong as other statin medicines. It does cause fewer side effects and is safer for your kidneys and liver.Lowers cholesterol. Mevacor (Lovastatin) can improve cholesterol, but it's not as strong as other statin medicines. Statin side effects can be difficult to deal with, but the benefits might outweigh the risks.Lowers triglycerides. Omega-3 Acid is good for lowering triglycerides (fats), but some people can't take it due to allergies.Lowers cholesterol. Antara (Fenofibrate) is good for lowering triglycerides (fats), but it's not as good as statins for improving cholesterol.Lowers cholesterol. Trilipix is good for lowering triglycerides (fats), but it's not as good as statins for improving cholesterol and cardiovascular disease risk.Lowers cholesterol. Vytorin is expensive and is no more effective than simvastatin by itself.Lowers cholesterol. Lipitor (atorvastatin) improves your cholesterol levels and is a common first treatment for people with high cholesterol or heart disease.Lowers cholesterol. Crestor (rosuvastatin) is one of the most effective statins to improve cholesterol. It's also available as a generic.Lowers cholesterol. Zocor (Simvastatin) is a good medication to improve your cholesterol. Statin side effects can be difficult to deal with, but the benefits might outweigh the risks.
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Reviews & ratings
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4.23Niaspan
Reviews for Niaspan (niacin)
43%
of people (All ages) say Niaspan (niacin) is worth it
31%
say it works well
19%
say it's a big hassle
380 reviews
Have you used Niaspan (niacin)?
Worth itNot sureNot worth it
Reviews for Zetia (ezetimibe)
42%
-1% worse vs. Niaspan (niacin)
34%
+3% better vs. Niaspan (niacin)
21%
-2% worse vs. Niaspan (niacin)
128 reviews
Have you used Zetia (ezetimibe)?
Worth itNot sureNot worth it
Reviews for Pravachol (pravastatin)
54%
+11% better vs. Niaspan (niacin)
44%
+13% better vs. Niaspan (niacin)
19%
Same vs. Niaspan (niacin)
426 reviews
Have you used Pravachol (pravastatin)?
Worth itNot sureNot worth it
Reviews for Mevacor (lovastatin)
43%
Same vs. Niaspan (niacin)
39%
+8% better vs. Niaspan (niacin)
22%
-3% worse vs. Niaspan (niacin)
Have you used Mevacor (lovastatin)?
Worth itNot sureNot worth it
Reviews for Lovaza (omega-3 acid)
59%
+16% better vs. Niaspan (niacin)
50%
+19% better vs. Niaspan (niacin)
28%
-9% worse vs. Niaspan (niacin)
Have you used Lovaza (omega-3 acid)?
Worth itNot sureNot worth it
Reviews for Antara (fenofibrate)
27%
-16% worse vs. Niaspan (niacin)
14%
-17% worse vs. Niaspan (niacin)
29%
-10% worse vs. Niaspan (niacin)
Have you used Antara (fenofibrate)?
Worth itNot sureNot worth it
Reviews for Trilipix (fenofibric acid)
50%
+7% better vs. Niaspan (niacin)
22%
-9% worse vs. Niaspan (niacin)
25%
-6% worse vs. Niaspan (niacin)
Have you used Trilipix (fenofibric acid)?
Worth itNot sureNot worth it
Reviews for Vytorin (ezetimibe / simvastatin)
53%
+10% better vs. Niaspan (niacin)
36%
+5% better vs. Niaspan (niacin)
19%
Same vs. Niaspan (niacin)
Have you used Vytorin (ezetimibe / simvastatin)?
Worth itNot sureNot worth it
Reviews for Lipitor (atorvastatin)
63%
+20% better vs. Niaspan (niacin)
51%
+20% better vs. Niaspan (niacin)
13%
+6% better vs. Niaspan (niacin)
1377 reviews
Have you used Lipitor (atorvastatin)?
Worth itNot sureNot worth it
Reviews for Crestor (rosuvastatin)
60%
+17% better vs. Niaspan (niacin)
47%
+16% better vs. Niaspan (niacin)
15%
+4% better vs. Niaspan (niacin)
751 reviews
Have you used Crestor (rosuvastatin)?
Worth itNot sureNot worth it
Reviews for Zocor (simvastatin)
61%
+18% better vs. Niaspan (niacin)
48%
+17% better vs. Niaspan (niacin)
14%
+5% better vs. Niaspan (niacin)
1176 reviews
Have you used Zocor (simvastatin)?
Worth itNot sureNot worth it
Side effects
NiaspanZetiapravastatinLovastatinOmega 3 AcidAntaraTrilipixVytorinAtorvastatinCrestorSimvastatin
  • Flushing 49%
  • Itching 6%
  • Rash 5%
More Niaspan side effects »
  • Common cold 1%
  • Sore throat 4%
  • Sinus infection 1%
  • Abnormal liver tests 3%
  • Joint pain 1%
  • Pain in arms and legs 1%
  • Muscle pain 3%
More Zetia side effects »
  • Upper respiratory infection 4%
  • Diarrhea 3%
  • Headache 2%
  • Chest pain 2%
  • Sore throat 2%
  • Rash 2%
  • Muscle pain 2%
More pravastatin side effects »
  • Diarrhea 1%
  • Muscle pain 1%
  • Muscle weakness 1%
  • Elevations of ck levels 11%
More Lovastatin side effects »
  • Eructation 3%
  • Change in taste 4%
  • Indigestion 1%
More Omega 3 Acid side effects »
  • Abnormal liver function tests 7%
  • Abdominal pain 1%
  • Increased ast 2%
  • Increased alt 1%
  • Increased creatine phosphokinase 2%
  • Constipation 1%
More Antara side effects »
  • Headache 13%
  • Back pain 6%
  • Pain in extremity 5%
  • Ear, nose, or throat infection 5%
  • Nausea 4%
  • Common cold 4%
  • Diarrhea 4%
  • Joint pain 4%
  • Pain 4%
  • Dizziness 4%
More Trilipix side effects »
  • Headache 1%
  • Any side effect 3%
  • Muscle pain 4%
  • Ear, nose, or throat infection 4%
  • Increased alt 4%
  • Diarrhea 3%
  • Flu 1%
  • Pain in extremity 1%
  • Unexplained muscle pain or weakness 1%
More Vytorin side effects »
  • Diarrhea 1%
  • Indigestion 1%
  • Muscle spasms 1%
  • Muscle pain 1%
More Atorvastatin side effects »
  • Headache 1%
  • Nausea 1%
  • Muscle pain 2%
  • Joint pain 1%
  • Diabetes mellitus 1%
  • Dizziness 1%
More Crestor side effects »
  • Upper respiratory infections 9%
  • Abdominal pain 7%
  • Constipation 7%
  • Headache 7%
  • Bronchitis 1%
  • Abnormal heart rhythm 1%
  • Nausea 5%
  • Scaly, itchy rash 2%
  • Upset stomach 3%
  • Vertigo 1%
More Simvastatin side effects »
How it works
NiaspanZetiapravastatinLovastatinOmega 3 AcidAntaraTrilipixVytorinAtorvastatinCrestorSimvastatin
Niaspan (Niacin) is a cholesterol-lowering medicine. Researchers don't know exactly how it works, but it seems to lower the amount of "bad" cholesterol (LDL) made by the liver.Zetia (ezetimibe) is a cholesterol-lowering medicine. It stops your body from absorbing cholesterol in food and helps process other forms of cholesterol.Pravachol (pravastatin) is cholesterol-lowering medicine called a statin. It lowers the amount of cholesterol your body makes, which helps lower "bad" cholesterol (LDL) and raise "good" cholesterol (HDL).Mevacor (Lovastatin) is cholesterol-lowering medicine called a statin. It lowers the amount of cholesterol your body makes, which helps lower "bad" cholesterol (LDL) and raise "good" cholesterol (HDL).Omega-3 Acid is a cholesterol-lowering medicine. Researchers don't know exactly how it works, but it may help the liver remove triglycerides from your body, and also prevent your body from making more triglycerides.Antara (Fenofibrate) is a cholesterol-lowering medicine. It removes triglycerides from your body and makes it easier to process "bad" cholesterol (LDL). This also increases "good" cholesterol (HDL).Trilipix is a cholesterol-lowering medicine. It removes triglycerides from your body and makes it easier to process "bad" cholesterol (LDL). This also increases "good" cholesterol (HDL).Vytorin is a combination cholesterol-lowering medicine. Simvastatin prevents your body from making "bad" cholesterol (LDL) while raising "good" cholesterol (HDL). Ezetimibe prevents cholesterol absorption in your intestines.Lipitor (atorvastatin) is a cholesterol-lowering medicine called a statin. It lowers the amount of cholesterol your body makes, which helps lower "bad" cholesterol (LDL) and raise "good" cholesterol (HDL).Crestor (rosuvastatin) is a statin medication that changes the amount of cholesterol your body makes. It lowers "bad" cholesterol (LDL) and improves your "good" cholesterol (HDL) levels.Zocor (Simvastatin) is cholesterol-lowering medicine called a statin. It lowers the amount of cholesterol your body makes, which helps lower "bad" cholesterol (LDL) and raise "good" cholesterol (HDL).
Type of medication
NiaspanZetiapravastatinLovastatinOmega 3 AcidAntaraTrilipixVytorinAtorvastatinCrestorSimvastatin
Prescription only
Prescription only
Prescription only
Prescription only
Prescription only
Prescription only
Prescription only
Prescription only
Prescription only
Prescription only
Prescription only
Available as
NiaspanZetiapravastatinLovastatinOmega 3 AcidAntaraTrilipixVytorinAtorvastatinCrestorSimvastatin
  • Pill
  • Extended release
  • Pill
  • Pill
  • Pill
  • Extended release
  • Pill
  • Pill
  • Pill
  • Extended release
  • Pill
  • Pill
  • Pill
  • Pill
  • Dissolving tablet
Used for
NiaspanZetiapravastatinLovastatinOmega 3 AcidAntaraTrilipixVytorinAtorvastatinCrestorSimvastatin
Risk factors for serious side effects
NiaspanZetiapravastatinLovastatinOmega 3 AcidAntaraTrilipixVytorinAtorvastatinCrestorSimvastatin
  • Taking Niaspan (Niacin) with statins
  • Heavy alcohol use
  • Past history of liver disease
  • Diabetes
  • Taking Niaspan (Niacin) with anticoagulants
  • Gout
Detailed Niaspan (niacin) risks & warnings »
    • Taking Zetia (ezetimibe) with statins
    • Past history of liver disease
    • Taking Zetia (ezetimibe) with statins
    Detailed Zetia (ezetimibe) risks & warnings »
    • Kidney disease
    • An underactive thyroid
    • Over age 65
    • Female gender
    • Taking other medicines to lower your cholesterol
    • Heavy alcohol use
    • History of chronic liver disease
    • Pregnancy
    • Breast feeding
    • Spironolactone use
    • Cimetidine use
    • Ketoconazole use
    Detailed Pravachol (pravastatin) risks & warnings »
    • Kidney disease
    • High dose of Mevacor (Lovastatin)
    • Combining with certain cholesterol-lowering drugs
    • Older age and female gender
    • Heavy alcohol use
    • History of chronic liver disease
    • Pregnancy
    • Breast feeding
    • Taking with certain drugs that increase the dose of Mevacor (Lovastatin) in the body
      Detailed Mevacor (lovastatin) risks & warnings »
      • Allergy to fish or shellfish
      • Atrial fibrillation
      Detailed Lovaza (omega-3 acid) risks & warnings »
      • Taking Antara (Fenofibrate) with statins
      • Past history of liver disease
        • Taking Antara (Fenofibrate) with anticoagulants
                Detailed Antara (fenofibrate) risks & warnings »
                • Taking Trilipix (Fenofibric Acid) with statins
                • Past history of liver disease
                  • Taking Trilipix (Fenofibric Acid) with anticoagulants
                            Detailed Trilipix (fenofibric acid) risks & warnings »
                            • Asian patients taking high-dose niacin
                            • Past history of liver disease
                            • heavy alcohol use
                            • Diabetes
                                • Pregnancy
                                Detailed Vytorin (ezetimibe / simvastatin) risks & warnings »
                                  • Heavy alcohol use
                                  • Prior history of chronic liver disease
                                  • Pregnancy
                                  • History of hemorrhagic strokes
                                    Detailed Lipitor (atorvastatin) risks & warnings »
                                    • Taking Coumadin (warfarin)
                                    • Age 65 or older
                                    • Taking higher doses of Crestor (rosuvastatin)
                                    • Diabetes
                                    • Heavy alcohol use
                                    • Prior history of chronic liver disease
                                    • Pregnancy
                                    Detailed Crestor (rosuvastatin) risks & warnings »
                                    • Kidney disease
                                    • High dose of Zocor (Simvastatin)
                                    • Combining Zocor (Simvastatin) with certain cholesterol-lowering drugs
                                    • Older age and female gender
                                    • Heavy alcohol use
                                    • History of chronic liver disease
                                    • Pregnancy
                                    • Breast feeding
                                    • Certain drugs can increase the dose of Zocor (Simvastatin) in the body
                                      Detailed Zocor (simvastatin) risks & warnings »
                                      Pregnancy

                                      Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

                                      Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

                                      Research studies with real people or animals found harmful effects on unborn babies. If you’re pregnant, the risks to your unborn baby outweigh the benefits.

                                      Research studies with real people or animals found harmful effects on unborn babies. If you’re pregnant, the risks to your unborn baby outweigh the benefits.

                                      Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

                                      Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

                                      Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

                                      Research studies with real people or animals found harmful effects on unborn babies. If you’re pregnant, the risks to your unborn baby outweigh the benefits.

                                      Research studies with real people or animals found harmful effects on unborn babies. If you’re pregnant, the risks to your unborn baby outweigh the benefits.

                                      Research studies with real people or animals found harmful effects on unborn babies. If you’re pregnant, the risks to your unborn baby outweigh the benefits.

                                      Research studies with real people or animals found harmful effects on unborn babies. If you’re pregnant, the risks to your unborn baby outweigh the benefits.

                                      Interactions
                                      NiaspanZetiapravastatinLovastatinOmega 3 AcidAntaraTrilipixVytorinAtorvastatinCrestorSimvastatin
                                      • Niaspan (Niacin) can interact with blood thinners and make you more likely to bleed. Your doctor may have you do regular blood tests and change your medication doses.
                                      No interactions related info.No interactions related info.
                                      • Certain medications can interact with this drug. Talk to your doctor or pharmacist.
                                      No interactions related info.No interactions related info.No interactions related info.No interactions related info.No interactions related info.No interactions related info.
                                      • Certain medications can interact with this drug. Talk to your doctor or pharmacist.
                                      Alcohol
                                      NiaspanZetiapravastatinLovastatinOmega 3 AcidAntaraTrilipixVytorinAtorvastatinCrestorSimvastatin
                                      • Don't have alcohol, spicy foods, or hot beverages right before you take this medicine.
                                      No alcohol related info.No alcohol related info.
                                      • You're at higher risk for these side effects if you are female, are 65 years or older, drink alcohol every day, take more than one medicine for cholesterol, or have liver disease, kidney disease, or diabetes.
                                      No alcohol related info.
                                      • Drinking large amounts of alcohol regularly can raise your risk of liver damage.
                                      • Don't drink a lot of alcohol while taking this medicine.
                                      No alcohol related info.No alcohol related info.
                                      • You're at higher risk for these side effects if you are a female, are 65 years or older, or drink more than two alcoholic drinks a day, take more than one medicine for cholesterol, or have liver disease, kidney disease, or diabetes.
                                      • You're more likely to have side effects if you're a female, are 65 years or older, drink alcohol every day, or take more than one medicine for cholesterol.
                                      • Don't have more than 2 glasses of alcohol a day since Crestor (rosuvastatin) can cause liver damage.
                                      • You're at higher risk for these side effects if you are female, are 65 years or older, drink alcohol every day, take more than one medicine for cholesterol, or have liver disease, kidney disease, or diabetes.
                                      Food
                                      NiaspanZetiapravastatinLovastatinOmega 3 AcidAntaraTrilipixVytorinAtorvastatinCrestorSimvastatin
                                      • You need to take it before bedtime with a low-fat snack.
                                      • Don't have alcohol, spicy foods, or hot beverages right before you take this medicine.
                                      • Niaspan (Niacin) can interact with blood thinners and make you more likely to bleed. Your doctor may have you do regular blood tests and change your medication doses.
                                      No food related info.No food related info.
                                      • Works best if you take it once a day after your evening meal.
                                      • You have to take it with food.
                                      • Take it with food.
                                      No food related info.No food related info.No food related info.No food related info.No food related info.No food related info.
                                      Kidneys and liver
                                      NiaspanZetiapravastatinLovastatinOmega 3 AcidAntaraTrilipixVytorinAtorvastatinCrestorSimvastatin
                                      No kidneys and liver related info.
                                      • Zetia (ezetimibe) can hurt your liver, especially if it is used with statins. Talk to your doctor if you have liver disease.
                                      • Pravachol (pravastatin) is less likely to cause muscle and kidney damage than other statin medicines.
                                      • If you have liver problems, Pravachol (pravastatin) is the safest statin to use.
                                      • Statins can cause digestive problems, blood sugar problems, muscle aches and stiffness, muscle injury, kidney damage, and liver damage. Some people have to stop taking this medicine because of these problems.
                                      • There are rare cases of muscle damage leading to kidney failure in people taking Mevacor (Lovastatin). The risk is greater in people with kidney disease or thyroid disease, are older and female and taking certain cholesterol-lowering medication combinations. Tell your doctor if you develop sudden muscle pain, weakness or fever and there is no known cause.
                                      • There are reports of liver damage in people who take Mevacor (Lovastatin), especially if they are heavy alcohol drinkers or have a history of liver disease. If you notice dark urine or yellowing of the eyes or skin, tell your doctor. Your doctor may also want to check your liver function periodically.
                                      No kidneys and liver related info.
                                      • Reports of liver damage have been reported in people who take Antara (Fenofibrate), especially in people with a history of liver disease. Your doctor may monitor your liver with blood tests on a regular basis.
                                      • Reports of liver damage have been reported in people who take Trilipix (Fenofibric Acid), especially in people with a history of liver disease. Your doctor may monitor your liver with blood tests on a regular basis.
                                      • People on Vytorin (Ezetimibe / Simvastatin) have reported muscle pain which may lead to muscle breakdown and kidney damage, especially in people of Asian ancestry who are also taking niacin. This has been very rare. Talk to your doctor if you suddenly develop muscle pain and a fever and you don't know why.
                                      • Statins such as Lipitor (atorvastatin) can cause digestive problems, blood sugar problems, muscle aches and stiffness, muscle injury, kidney damage, or liver damage. Some people need to stop taking this medicine if these problems occur.
                                      • Eating grapefruit or drinking grapefruit juice can raise your risk of liver damage while taking Lipitor (atorvastatin).
                                      • People on Lipitor (atorvastatin) have reported muscle pain, which may lead to muscle and kidney damage. This is more likely to happen if you're older and you're taking higher doses of Lipitor (atorvastatin). If you suddenly feel muscle pain or weakness and you haven't been exercising, stop taking Lipitor (atorvastatin) and talk to your doctor right away.
                                      • Liver damage has been reported in people who take Lipitor (atorvastatin). If you notice dark urine or yellowing of your eyes or skin, talk to your doctor. Your doctor might run blood tests to check your liver.
                                      • People with liver disease, kidney disease, or diabetes are also more likely to have side effects from Crestor (rosuvastatin).
                                      • People on Crestor (rosuvastatin) have reported muscle pain which can lead to muscle or kidney damage. This is more likely to happen if you're older and if you're taking higher doses of Crestor (rosuvastatin). If you suddenly feel severe muscle pain or weakness and you haven't been exercising, stop taking Crestor (rosuvastatin) and talk to your doctor right away.
                                      • Crestor (rosuvastatin) can cause liver damage. If your urine is darker than normal or if you notice a yellow color in your eyes or skin, talk to your doctor. Your doctor may run some tests to see how your liver is working.
                                      • Statins can cause digestive problems, blood sugar problems, muscle aches and stiffness, muscle injury, kidney damage, and liver damage. Some people have to stop taking this medicine because of these problems.
                                      • There are rare cases of muscle damage leading to kidney failure in people taking Zocor (Simvastatin). The risk is greater in people with kidney disease or thyroid disease, are older and female and taking certain cholesterol-lowering medication combinations. Tell your doctor if you develop sudden muscle pain, weakness or fever and there is no known cause.
                                      • There are reports of liver damage in people who take Zocor (Simvastatin), especially if they are heavy alcohol drinkers or have a history of liver disease. If you notice dark urine or yellowing of the eyes or skin, tell your doctor. Your doctor may also want to check your liver function periodically.
                                      Pain
                                      NiaspanZetiapravastatinLovastatinOmega 3 AcidAntaraTrilipixVytorinAtorvastatinCrestorSimvastatin
                                      • It can cause flushing and stomach pain or discomfort.
                                      • Zetia (ezetimibe) can hurt your liver, especially if it is used with statins. Talk to your doctor if you have liver disease.
                                      No pain related info.
                                      • Combining certain medications can increase the risk of muscle pain (myopathy), muscle damage (rhabdomyolysis) and kidney damage. Talk to your doctor or pharmacist when taking any new medications.
                                      No pain related info.No pain related info.No pain related info.No pain related info.
                                      • Tell your doctor if you suddenly feel severe muscle pain, fever, or weakness.
                                      • Crestor (rosuvastatin) isn't safe to use if you're pregnant since it can hurt the fetus.
                                      • Call your doctor if you have sudden muscle pain, fever, or weakness.
                                      • Combining certain medications can increase the risk of muscle pain (myopathy), muscle damage (rhabdomyolysis) and kidney damage. Talk to your doctor or pharmacist when taking any new medications.
                                      Upsides and benefits
                                      NiaspanZetiapravastatinLovastatinOmega 3 AcidAntaraTrilipixVytorinAtorvastatinCrestorSimvastatin
                                      • Lowers "bad" cholesterol (LDL) and raises "good" cholesterol (HDL) in people who have trouble doing this through diet and exercise.
                                      • Good for lowering triglycerides (fats).
                                      • Lowers "bad" cholesterol (LDL) and raises "good" cholesterol (HDL) in people who have trouble doing this through diet and exercise.
                                      • Can be used with other medicines to improve cholesterol.
                                      • Available in a combination pill with simvastatin.
                                      • Available as a generic.
                                      • Compared to other statins, Pravachol (pravastatin) has fewer interactions with medicines.
                                      • Pravachol (pravastatin) is less likely to cause muscle and kidney damage than other statin medicines.
                                      • If you have liver problems, Pravachol (pravastatin) is the safest statin to use.
                                      • It's available as a generic.
                                      • Lowers "bad" cholesterol (LDL) and triglycerides (fats) and raises "good" cholesterol (HDL) in people who have trouble doing this through diet and exercise.
                                      • Can lower the risk of heart attack, stroke, and death, particularly if you have diabetes, high blood pressure, obesity, or a history of smoking.
                                      • Lowers triglycerides (fats) when combined with exercise and a low cholesterol diet.
                                      • In studies, Omega-3 Acid has lowered the risk of stroke and heart attack leading to death, especially in people with high cholesterol or high triglycerides.
                                      • Lowers "bad" cholesterol (LDL) and triglycerides (fats) and raises "good" cholesterol (HDL) in people who have trouble doing this through diet and exercise.
                                      • Lowers "bad" cholesterol (LDL) and triglycerides (fats) and raises "good" cholesterol (HDL) in people who have trouble doing this through diet and exercise.
                                      • Good medicine for lowering triglycerides.
                                      • A 2-in-1 cholesterol-lowering combination medicine.
                                      • Lowers "bad" cholesterol (LDL) and raises "good" cholesterol (HDL) in people who have trouble doing this through diet and exercise.
                                      • Lowers "bad" cholesterol (LDL) and triglycerides (fats), and raises "good" cholesterol (HDL) in people who have trouble doing this through diet and exercise.
                                      • Lipitor (atorvastatin) can lower the risk of heart attack, stroke, and death, particularly if you have diabetes, high blood pressure, obesity, or a history of smoking.
                                      • It's one of the strongest cholesterol-lowering statin medications.
                                      • Lipitor (atorvastatin) is a good option for people who have high cholesterol and diabetes.
                                      • It's available as a generic drug and can be used in combination with other cholesterol lowering drugs.
                                      • It's a good first choice medicine for lowering cholesterol levels when diet and exercise aren't enough.
                                      • Slows down the buildup of fatty deposits in your blood vessels, otherwise known as a hardening of the arteries.
                                      • In clinical studies, Crestor (rosuvastatin) has the strongest effect on lowering "bad" cholesterol compared to other statins.
                                      • Can lower your risk of heart attack, stroke, and death, particularly if you have diabetes, high blood pressure, obesity, or a history of smoking.
                                      • Available as a generic drug.
                                      • Lowers "bad" cholesterol (LDL) and triglycerides (fats) and raises "good" cholesterol (HDL) in people who have trouble doing this through diet and exercise.
                                      • Can lower the risk of heart attack, stroke, and death, particularly if you have diabetes, high blood pressure, obesity, or a history of smoking.
                                      Downsides and risks
                                      NiaspanZetiapravastatinLovastatinOmega 3 AcidAntaraTrilipixVytorinAtorvastatinCrestorSimvastatin
                                      • By itself, Niaspan (Niacin) isn't as effective as statins for improving cholesterol levels.
                                      • It can cause flushing and stomach pain or discomfort.
                                      • You need to take it before bedtime with a low-fat snack.
                                      • If you miss doses often, you may need to re-start taking the medicine more regularly at a lower dose.
                                      • Doesn't lower triglycerides (fats).
                                      • Hasn't been shown to lower the risk of heart attacks or heart disease.
                                      • By itself, it isn't as effective as statins for improving cholesterol.
                                      • Pravachol (pravastatin) isn't as strong as other statins in lowering your cholesterol.
                                      • You'll still need to eat a low fat diet and exercise regularly to get the full benefit of Pravachol (pravastatin).
                                      • Not the best choice for people who have very high cholesterol levels.
                                      • Statins can cause digestive problems, blood sugar problems, muscle aches and stiffness, muscle injury, kidney damage, and liver damage. Some people have to stop taking this medicine because of these problems.
                                      • You're at higher risk for these side effects if you are female, are 65 years or older, drink alcohol every day, take more than one medicine for cholesterol, or have liver disease, kidney disease, or diabetes.
                                      • Not safe to use if you're pregnant.
                                      • You can't take it if you're allergic to fish or shellfish.
                                      • You have to take it with food.
                                      • In studies, it didn't lower heart disease in people with Type 2 diabetes.
                                      • According to new guidelines, you shouldn't take this medicine by itself to lower cholesterol.
                                      • Drinking large amounts of alcohol regularly can raise your risk of liver damage.
                                      • Different forms and strengths of this medication can't be substituted for each other.
                                      • In clinical studies, Trilipix hasn't lowered cholesterol or the risk of heart attack and stroke better than statins.
                                      • Different forms and strengths of this medication can't be substituted for each other.
                                      • In clinical studies, simvastatin/ezetimibe hasn't controlled cholesterol better than simvastatin alone.
                                      • There's no generic available, so it can be expensive.
                                      • Statins such as Lipitor (atorvastatin) can cause digestive problems, blood sugar problems, muscle aches and stiffness, muscle injury, kidney damage, or liver damage. Some people need to stop taking this medicine if these problems occur.
                                      • You're at higher risk for these side effects if you are a female, are 65 years or older, or drink more than two alcoholic drinks a day, take more than one medicine for cholesterol, or have liver disease, kidney disease, or diabetes.
                                      • Eating grapefruit or drinking grapefruit juice can raise your risk of liver damage while taking Lipitor (atorvastatin).
                                      • You're more likely to have side effects if you're a female, are 65 years or older, drink alcohol every day, or take more than one medicine for cholesterol.
                                      • People with liver disease, kidney disease, or diabetes are also more likely to have side effects from Crestor (rosuvastatin).
                                      • Crestor (rosuvastatin) isn't safe to use if you're pregnant since it can hurt the fetus.
                                      • Statins can cause digestive problems, blood sugar problems, muscle aches and stiffness, muscle injury, kidney damage, and liver damage. Some people have to stop taking this medicine because of these problems.
                                      • You're at higher risk for these side effects if you are female, are 65 years or older, drink alcohol every day, take more than one medicine for cholesterol, or have liver disease, kidney disease, or diabetes.
                                      • Not safe to use if you're pregnant.
                                      Tips from our pharmacists for people taking the medication
                                      NiaspanZetiapravastatinLovastatinOmega 3 AcidAntaraTrilipixVytorinAtorvastatinCrestorSimvastatin
                                      • Take Niaspan (Niacin) at bedtime with a low-fat snack.
                                      • Don't have alcohol, spicy foods, or hot beverages right before you take this medicine.
                                      • Can cause make your skin feel hot and change color. Your doctor may tell you to take an aspirin 30 minutes before you take Niaspan (Niacin) to reduce the flushing.
                                      • Call your doctor if you feel unexplained muscle pain.
                                      • Niaspan (Niacin) works differently from other medicines you can buy over-the-counter. Don't switch it with other medicines unless your doctor agrees.
                                      • Lowers bad cholesterol and raises good cholesterol.
                                      • Tell your doctor if you develop bone or muscle pain.
                                      • Can be used with other medications to lower cholesterol.
                                      • Good alternative to statins if you can't tolerate statins or are unable to control cholesterol with statins alone.
                                      • Can cause diarrhea or increase your chance of getting colds.
                                      • Lowers bad cholesterol and triglycerides, and raises good cholesterol.
                                      • Most people reach their target cholesterol levels in 4 to 6 weeks.
                                      • Don't eat grapefruit and drink grapefruit juice while taking this medicine.
                                      • Tell your doctor if you develop sudden muscle pain, fever, or weakness.
                                      • Also let your doctor know if you notice dark urine or yellowing of your eyes or skin.
                                      • You'll need to stop taking Pravachol (pravastatin) if you get pregnant.
                                      • Lowers bad cholesterol and triglycerides, and raises good cholesterol.
                                      • Most people reach their target cholesterol levels in 4 to 6 weeks.
                                      • Works best if you take it once a day after your evening meal.
                                      • Avoid grapefruit and grapefruit juice while taking this medicine.
                                      • Tell your doctor if you develop sudden muscle pain, fever, or weakness.
                                      • Tell your doctor if you notice dark urine or yellowing of the eyes or skin.
                                      • Certain medications can interact with this drug. Talk to your doctor or pharmacist.
                                      • Lowers triglycerides.
                                      • Take it with food.
                                      • Swallow capsules whole.
                                      • Can cause burping and changes in taste.
                                      • Don't use if you have an allergy to fish or shellfish.
                                      • You should use this medicine in combination with a healthy diet.
                                      • Lowers triglycerides.
                                      • Can cause backache or headache.
                                      • Call your doctor if you develop muscle or abdominal pain.
                                      • Don't drink a lot of alcohol while taking this medicine.
                                      • Also taking Welchol or Questran? Take this medicine at least 1 hour before or 6 hours after.
                                      • You should use this medicine in combination with a healthy diet.
                                      • Can be used with other medications to help lower cholesterol.
                                      • Lowers triglycerides.
                                      • Can raise your chance of getting colds and flu.
                                      • Call your doctor if you develop muscle or abdominal pain.
                                      • Also taking Welchol or Questran? Take this medicine at least 2 hours before or 4 hours after.
                                      • Take it in the evening.
                                      • Avoid grapefruit and grapefruit juice while taking this medicine.
                                      • Can cause headaches or diarrhea.
                                      • Call your doctor if you develop muscle pain.
                                      • Also taking Welchol or Questran? Take this medicine at least 2 hours before or 4 hours after.
                                      • Lowers bad cholesterol and triglycerides, and raises good cholesterol.
                                      • Don't eat grapefruit or drink grapefruit juice while taking this medicine.
                                      • Tell your doctor if you suddenly feel severe muscle pain, fever, or weakness.
                                      • Also tell your doctor if you have dark urine or if you notice a yellow tint in your eyes or skin.
                                      • Lipitor (atorvastatin) isn't safe to use if you're pregnant.
                                      • Lowers bad cholesterol and triglycerides, and raises good cholesterol levels.
                                      • Don't have more than 2 glasses of alcohol a day since Crestor (rosuvastatin) can cause liver damage.
                                      • Don't take antacids for at least 2 hours before and after taking Crestor (rosuvastatin).
                                      • Call your doctor if you have sudden muscle pain, fever, or weakness.
                                      • Let your doctor know if you have dark urine or a yellow color in your eyes or skin.
                                      • Lowers bad cholesterol and triglycerides, and raises good cholesterol.
                                      • Most people reach their target cholesterol levels in 4 to 6 weeks.
                                      • Avoid grapefruit and grapefruit juice while taking this medicine.
                                      • Tell your doctor if you develop sudden muscle pain, fever, or weakness.
                                      • Tell your doctor if you notice dark urine or yellowing of the eyes or skin.
                                      • Certain medications can interact with this drug. Talk to your doctor or pharmacist.
                                      Learn more
                                      More about NiaspanSide effectsReviews & ratingsAlternativesFDA package insert
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                                      More about pravastatinSide effectsReviews & ratingsFDA package insert
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