Prescription onlyLower-cost generic available

Nitrostat Alternatives

(Nitroglycerin)

  • Dissolving tablet
  • Pill
  • Extended release
  • Patch
  • Mouth spray
  • Cream, gel, or ointment
  • Rectal gel or ointment
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Compare Nitrostat (Nitroglycerin) to alternatives

These medications are comparable to Nitrostat (Nitroglycerin) or used for similar purposes.

Nitrostat
(Nitroglycerin)

Imdur
(Isosorbide Mononitrate)

Isordil
(Isosorbide Dinitrate)

Relieves chest pain. Nitroglycerin is the fastest-working medicine to relieve chest pain, but make sure to sit down before taking it.Relieves chest pain. Isosorbide mononitrate is good for chest pain, but you have to be able to stick to your dosing schedule or it won't work as well.Relieves chest pain. Isosorbide dinitrate is good for chest pain, but you have to be able to stick to your dosing schedule or it won't work as well.
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Reviews & ratings
Button Group. All currently active
Button Group. All currently active
4.725806451612903Nitrostat
Reviews for Nitrostat (Nitroglycerin)
40%
of people say Nitrostat (Nitroglycerin) is worth it
50%
say it works well
21%
say it's a big hassle
Reviews for Imdur (Isosorbide Mononitrate)
48%
+8% vs. Nitrostat (Nitroglycerin)
30%
20% vs. Nitrostat (Nitroglycerin)
33%
12% vs. Nitrostat (Nitroglycerin)
Reviews for Isordil (Isosorbide Dinitrate)
46%
+6% vs. Nitrostat (Nitroglycerin)
24%
26% vs. Nitrostat (Nitroglycerin)
20%
+1% vs. Nitrostat (Nitroglycerin)
Side effects
NitrostatImdurIsordil
  • Headache 45%
  • Lightheadedness 2%
More Nitrostat side effects »
  • Headache 42%
  • Dizziness 7%
More Imdur side effects »

The Isordil FDA package insert doesn’t have numbers about how common side effects are.

More about Isordil side effects »
How it works
NitrostatImdurIsordil
Nitroglycerin is a nitrate. It dilates blood vessels all over the body. This makes it less work for the heart to pump, which relieves heart-related chest pain.Isosorbide mononitrate is a nitrate. It dilates blood vessels all over the body. This makes it less work for the heart to pump, which relieves heart-related chest pain.Isosorbide dinitrate is a nitrate. It dilates blood vessels all over the body. This makes it less work for the heart to pump, which relieves heart-related chest pain.
Type of medication
NitrostatImdurIsordil
Vasodilator
Nitrate
Prescription only
Vasodilator
Nitrate
Prescription only
Vasodilator
Nitrate
Prescription only
Available as
NitrostatImdurIsordil
  • Dissolving tablet
  • Pill
  • Extended release
  • Patch
  • Mouth spray
  • Cream, gel, or ointment
  • Rectal gel or ointment
  • Pill
  • Extended release
  • Pill
  • Extended release
Used for (click to learn more)
NitrostatImdurIsordil
Risk factors for serious side effects
NitrostatImdurIsordil
  • Concurrent use of erectile dysfunction medicine
  • Age 65 years or older
  • Alcohol use
  • Long term use
Detailed Nitrostat (Nitroglycerin) risks & warnings »
Coming soon.Coming soon.
Pregnancy category
NitrostatImdurIsordil
CFDA pregnancy category (Weigh risks vs. benefits)

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

See the FDA package insert
CFDA pregnancy category (Weigh risks vs. benefits)

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

See the FDA package insert
CFDA pregnancy category (Weigh risks vs. benefits)

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

See the FDA package insert
Alcohol
  • Don't drink alcohol while taking this medicine. It can make dizziness worse.
  • Don't drink alcohol while taking this medicine. It can make you really dizzy.
  • Don't drink alcohol while taking this medicine. It can make you really dizzy.
Food
No specific food-related info.No specific food-related info.No specific food-related info.
Kidneys and liver
No specific kidneys and liver-related info.No specific kidneys and liver-related info.No specific kidneys and liver-related info.
Sex
No specific sex-related info.No specific sex-related info.No specific sex-related info.
Sleep
No specific sleep-related info.No specific sleep-related info.No specific sleep-related info.
Weight
No specific weight-related info.No specific weight-related info.No specific weight-related info.
Upsides and benefits
NitrostatImdurIsordil
  • First-choice treatment for quick relief of heart-related chest pain (angina).
  • Can also be used to prevent chest pain from happening.
  • Available in various forms that take effect at different speeds and stay in your system for different lengths of time. Sublingual form works the fastest (1-3 minutes) but lasts the shortest in your body (25 minutes), while the patch form takes the longest to start working (30 minutes) but lasts the longest (10-12 hours). Your doctor can help you find the one that's best for you.
  • Prevents heart-related chest pain (angina) from the narrowing of heart blood vessels (coronary artery disease).
  • Treats and prevents heart-related chest pain (angina) from the narrowing of heart blood vessels (coronary artery disease).
Downsides and risks
NitrostatImdurIsordil
  • You can develop tolerance to this medicine over time, which means that the same dose becomes less effective. You have to stick to a really specific dosing schedule for the extended-release, ointment, and patch forms to prevent this from happening.
  • Headaches are normal with this medicine and they go away as your body gets used to it, but they can be severe or not tolerable for some people.
  • You can develop tolerance to this medicine over time, which means that the same dose becomes less effective. You have to stick to a really specific dosing schedule to prevent this from happening.
  • Headaches are normal with this medicine and they go away as your body gets used to it, but they can be severe or not tolerable for some people.
  • You can develop tolerance to this medicine over time, which means that the same dose becomes less effective. You have to stick to a really specific dosing schedule to prevent this from happening.
  • Headaches are normal with this medicine and they go away as your body gets used to it, but they can be severe or not tolerable for some people.
Tips from our pharmacists for people taking the medication
NitrostatImdurIsordil
  • Can cause headaches, dizziness, lightheadedness, or fainting. Sit down before taking this medicine in case you get dizzy.
  • Take it exactly as instructed by your doctor.
  • Usually relieves chest pain in 1 to 5 minutes. If pain continues, you can take up to 3 doses, with 5 minutes in between each dose. Call 911 or go to the hospital if you've taken a second dose.
  • Don't drink alcohol while taking this medicine. It can make dizziness worse.
  • Tell your doctor if you're taking any medicine for erectile dysfunction.
  • Can cause headaches, dizziness, lightheadedness, or fainting. Headache can be a sign that the medicine is working.
  • Don't drink alcohol while taking this medicine. It can make you really dizzy.
  • Tell your doctor if you're taking any medicine for erectile dysfunction.
  • Don't stop taking this medicine suddenly.
  • Can cause headaches, dizziness, lightheadedness, or fainting.
  • Don't drink alcohol while taking this medicine. It can make you really dizzy.
  • Tell your doctor if you're taking any medicine for erectile dysfunction.
  • Don't stop taking this medicine suddenly.
Learn more
More about NitrostatSide effectsReviews & ratingsAlternativesFDA package insert
More about ImdurSide effectsReviews & ratingsFDA package insert
More about IsordilSide effectsReviews & ratingsFDA package insert