Prescription onlyLower-cost generic availableClass: Cardiovascular

NitrostatAlternatives

(nitroglycerin)

Prescription onlyLower-cost generic availableClass: Cardiovascular
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Compare Nitrostat (nitroglycerin) to alternatives

These medications are comparable to Nitrostat (nitroglycerin) or used for similar purposes.

Nitrostat
(nitroglycerin)

Imdur
(isosorbide mononitrate)

Isordil
(isosorbide dinitrate)

Relieves chest pain. Nitroglycerin is the fastest-working medicine to relieve chest pain, but make sure to sit down before taking it.Relieves chest pain. Isosorbide mononitrate is good for chest pain, but you have to be able to stick to your dosing schedule or it won't work as well.Relieves chest pain. Isosorbide dinitrate is good for chest pain, but you have to be able to stick to your dosing schedule or it won't work as well.
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Prices and coupon for 30 (0.2mg) patches of nitroglycerin
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Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
4.76Nitrostat
Reviews for Nitrostat (nitroglycerin)
41%
of people (All ages) say Nitrostat (nitroglycerin) is worth it
51%
say it works well
21%
say it's a big hassle
Have you used Nitrostat (nitroglycerin)?
Worth itNot sureNot worth it
Reviews for Imdur (isosorbide mononitrate)
47%
+6% better vs. Nitrostat (nitroglycerin)
29%
-22% worse vs. Nitrostat (nitroglycerin)
32%
-11% worse vs. Nitrostat (nitroglycerin)
Have you used Imdur (isosorbide mononitrate)?
Worth itNot sureNot worth it
Reviews for Isordil (isosorbide dinitrate)
46%
+5% better vs. Nitrostat (nitroglycerin)
24%
-27% worse vs. Nitrostat (nitroglycerin)
20%
+1% better vs. Nitrostat (nitroglycerin)
Have you used Isordil (isosorbide dinitrate)?
Worth itNot sureNot worth it
Side effects
NitrostatImdurIsordil
  • Headache 45%
  • Lightheadedness 2%
  • Low blood pressure 4%
More Nitrostat side effects »
  • Dizziness 4%
More Imdur side effects »

The Isordil FDA package insert doesn’t have numbers about how common side effects are.

More about Isordil side effects »
How it works
NitrostatImdurIsordil
Nitroglycerin is a nitrate. It dilates blood vessels all over the body. This makes it less work for the heart to pump, which relieves heart-related chest pain.Isosorbide mononitrate is a nitrate. It dilates blood vessels all over the body. This makes it less work for the heart to pump, which relieves heart-related chest pain.Isosorbide dinitrate is a nitrate. It dilates blood vessels all over the body. This makes it less work for the heart to pump, which relieves heart-related chest pain.
Type of medication
NitrostatImdurIsordil
Prescription only
Prescription only
Prescription only
Available as
NitrostatImdurIsordil
  • Dissolving tablet
  • Pill
  • Extended release
  • Patch
  • Mouth spray
  • Cream, gel, or ointment
  • Rectal gel or ointment
  • Pill
  • Extended release
  • Pill
  • Extended release
Used for
NitrostatImdurIsordil
Risk factors for serious side effects
NitrostatImdurIsordil
  • Concurrent use of erectile dysfunction medicine
  • Age 65 years or older
  • Alcohol use
  • Long term use
Detailed Nitrostat (nitroglycerin) risks & warnings »
  • Concurrent use of erectile dysfunction medicine
  • Age 65 years or older
  • Alcohol use
  • Long term use
Detailed Imdur (isosorbide mononitrate) risks & warnings »
  • Age 65 years or older
  • Taking drugs for erectile dysfunction
  • Alcohol use
    Detailed Isordil (isosorbide dinitrate) risks & warnings »
    Pregnancy

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    Alcohol
    NitrostatImdurIsordil
    • Don't drink alcohol while taking this medicine. It can make dizziness worse.
    • Don't drink alcohol while taking this medicine. It can make you really dizzy.
    • Don't drink alcohol while taking this medicine. It can make you really dizzy.
    Pain
    NitrostatImdurIsordil
    • First-choice treatment for quick relief of heart-related chest pain (angina).
    • Usually relieves chest pain in 1 to 5 minutes. If pain continues, you can take up to 3 doses, with 5 minutes in between each dose. Call 911 or go to the hospital if you've taken a second dose.
    No pain related info.No pain related info.
    Upsides and benefits
    NitrostatImdurIsordil
    • First-choice treatment for quick relief of heart-related chest pain (angina).
    • Can also be used to prevent chest pain from happening.
    • Available in various forms that take effect at different speeds and stay in your system for different lengths of time. Sublingual form works the fastest (1-3 minutes) but lasts the shortest in your body (25 minutes), while the patch form takes the longest to start working (30 minutes) but lasts the longest (10-12 hours). Your doctor can help you find the one that's best for you.
    • Prevents heart-related chest pain (angina) from the narrowing of heart blood vessels (coronary artery disease).
    • Treats and prevents heart-related chest pain (angina) from the narrowing of heart blood vessels (coronary artery disease).
    Downsides and risks
    NitrostatImdurIsordil
    • You can develop tolerance to this medicine over time, which means that the same dose becomes less effective. You have to stick to a really specific dosing schedule for the extended-release, ointment, and patch forms to prevent this from happening.
    • Headaches are normal with this medicine and they go away as your body gets used to it, but they can be severe or not tolerable for some people.
    • You can develop tolerance to this medicine over time, which means that the same dose becomes less effective. You have to stick to a really specific dosing schedule to prevent this from happening.
    • Headaches are normal with this medicine and they go away as your body gets used to it, but they can be severe or not tolerable for some people.
    • You can develop tolerance to this medicine over time, which means that the same dose becomes less effective. You have to stick to a really specific dosing schedule to prevent this from happening.
    • Headaches are normal with this medicine and they go away as your body gets used to it, but they can be severe or not tolerable for some people.
    Tips from our pharmacists for people taking the medication
    NitrostatImdurIsordil
    • Can cause headaches, dizziness, lightheadedness, or fainting. Sit down before taking this medicine in case you get dizzy.
    • Take it exactly as instructed by your doctor.
    • Usually relieves chest pain in 1 to 5 minutes. If pain continues, you can take up to 3 doses, with 5 minutes in between each dose. Call 911 or go to the hospital if you've taken a second dose.
    • Don't drink alcohol while taking this medicine. It can make dizziness worse.
    • Tell your doctor if you're taking any medicine for erectile dysfunction.
    • Can cause headaches, dizziness, lightheadedness, or fainting. Headache can be a sign that the medicine is working.
    • Don't drink alcohol while taking this medicine. It can make you really dizzy.
    • Tell your doctor if you're taking any medicine for erectile dysfunction.
    • Don't stop taking this medicine suddenly.
    • Can cause headaches, dizziness, lightheadedness, or fainting.
    • Don't drink alcohol while taking this medicine. It can make you really dizzy.
    • Tell your doctor if you're taking any medicine for erectile dysfunction.
    • Don't stop taking this medicine suddenly.
    Learn more
    More about NitrostatSide effectsReviews & ratingsAlternativesFDA package insert
    Have you used Nitrostat (nitroglycerin)?
    Worth itNot sureNot worth it
    More about ImdurSide effectsReviews & ratingsFDA package insert
    Have you used Imdur (isosorbide mononitrate)?
    Worth itNot sureNot worth it
    More about IsordilSide effectsReviews & ratingsFDA package insert
    Have you used Isordil (isosorbide dinitrate)?
    Worth itNot sureNot worth it