Prescription onlyLower-cost generic availableClass: Cardiovascular



Prescription onlyLower-cost generic availableClass: Cardiovascular
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Lowers blood pressure.

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Our bottom line

Norvasc (Amlodipine) works well to lower blood pressure and prevent chest pain. You can't miss doses, and you might get persistent swelling.

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  • A first-choice blood pressure treatment for many people.
  • Calcium channel blockers work especially well for African Americans to lower blood pressure.
  • Lowers the risk of heart attack and stroke.
  • Prevents heart-related chest pain (angina) if you take it regularly.
  • Each dose lasts longer than other calcium channel blockers, which keeps blood pressure consistent without big ups and downs.
  • Particularly good at lowering systolic blood pressure (the top number), so it's a good option for older people who can commonly get high blood pressure only in the top number.
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  • Calcium channel blockers can cause swelling in your limbs. If this happens for you, it probably won't get better over time, so talk to your doctor about alternatives if it bothers you.
  • Women are more likely to have side effects (especially swelling) from Amlodipine than men.
  • Some people might experience flushing with this medication.
  • You can't miss doses. Stopping Amlodipine suddenly can cause your blood pressure to go up suddenly, which raises the risk of heart attack and stroke.
  • If you have severe heart disease, using Amlodipine might increase your risk of chest pain or heart attack during the time right after starting the medication or raising the dosage.
  • Might not be a good choice if you have liver disease.
How it works

Norvasc (Amlodipine) is a calcium channel blocker. It lowers blood pressure by slowing your heart rate and relaxing your blood vessels. Your heart gets more oxygen and doesn't have to work as hard to pump, which can relieve chest pain.

What to expect when you take Norvasc (amlodipine) for Lowers blood pressure

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Side effect rates for Norvasc (amlodipine)

2980 From clinical trials of Norvasc / High blood pressure or coronary artery disease
  • Fatigue
  • Nausea
  • Abdominal pain

Risks and Warnings for Norvasc (amlodipine)

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    • Higher risk if:
    • Age 65 years or older

    You can experience dizziness due to a drop in blood pressure. This is a common early side effect of many medications that lower blood pressure including Norvasc (Amlodipine). Typically this will go away over time as your body gets used to the lowered blood pressure. It may be more likely to occur when you change posture, such as going from sitting to standing. If you're sensitive to low blood pressure, change position slowly. If the dizziness is unbearable then talk with your doctor. A different medication may be better for you.

Common concerns from people taking Norvasc (amlodipine)

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  • Interacts with the cholesterol medicine Simvastatin.
Kidneys and liver
  • Might not be a good choice if you have liver disease.
  • Your body uses your liver to break down Norvasc (Amlodipine) and remove it from your blood. If you have liver disease you may not be able to remove Norvasc (Amlodipine) as quickly from your blood as someone with a healthy liver. You should increase the dose of Norvasc (Amlodipine) slowly and watch closely for how it is working in your body. Increasing the dose slowly will lower your chances of having side effects.
  • Worsening heart pain or increased risk of heart attack is possible when you first start taking Norvasc (Amlodipine). This can also happen after you increase the dose of Norvasc (Amlodipine). Notify your doctor immediately if you experience any heart pain, radiating jaw pain, crushing chest pain, or persistent racing heartbeat.
  • Swelling of the ankles, chest pain, flushing, sweating, some red spots on my legs.