Prescription onlyLower-cost generic available



Prescription onlyLower-cost generic available
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Makes you feel awake.

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Our bottom line

Nuvigil (Armodafinil) is effective in improving alertness, but it can interact with other medications and shouldn't be used long-term.

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  • Effective in treating excess sleepiness in shift work sleep disorder (SWSD).
  • Doesn't negatively affect daytime sleep.
  • It's a non-amphetamine medication that helps improve alertness.


  • Nuvigil (Armodafinil) can be habit-forming, so it's typically not used for long-term treatment.
  • Interacts with many other medications.
  • Reduces the effectiveness of birth control pills. You need to use an additional contraceptive method while taking Nuvigil (Armodafinil).
  • Nuvigil (Armodafinil) is processed in the liver so it's not a good choice if you have liver, or even kidney, problems.
  • Not available as a generic.
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Side effect rates for Nuvigil (Armodafinil)

1090 From clinical trials of Nuvigil / Excessive sleepiness from sleep apnea or shift work
  • Headache
  • Nausea
  • Adverse events
  • Sleep difficulty
  • Dizziness
  • Diarrhea
  • Dry mouth
  • Anxiety
  • Heart pounding or racing sensation
  • Thirst

Risks and Warnings for Nuvigil (Armodafinil)

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    • Higher risk if:
    • Taking with alcohol
    • Taking other medicines that make you less alert

    Nuvigil (Armodafinil) lowers your ability to focus, think, and react. Be careful and avoid activities that require you to be alert, such as driving a car or operating machinery, until you know how this medication affects you.

Common concerns from people taking Nuvigil (Armodafinil)

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  • Interacts with many other medications.
  • Don't drink alcohol with Nuvigil (Armodafinil).
Kidneys and liver
  • Nuvigil (Armodafinil) is processed in the liver so it's not a good choice if you have liver, or even kidney, problems.
  • Nuvigil (Armodafinil) is processed by the kidney and liver. If you have kidney or liver problems, you may need a different dose, or other medication, to prevent increased risk of side effects.