Prescription onlyLower-cost generic available

Nuvigil

(Armodafinil)

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Makes you feel awake.

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Prescription onlyLower-cost generic available

Our pharmacists’ bottom line

Nuvigil (Armodafinil) is effective in improving alertness, but it can interact with other medications and shouldn't be used long-term.

  • Effective in treating excess sleepiness in shift work sleep disorder (SWSD).
  • Doesn't negatively affect daytime sleep.
  • It's a non-amphetamine medication that helps improve alertness.
  • Nuvigil (Armodafinil) can be habit-forming, so it's typically not used for long-term treatment.
  • Interacts with many other medications.
  • Reduces the effectiveness of birth control pills. You need to use an additional contraceptive method while taking Nuvigil (Armodafinil).
  • Nuvigil (Armodafinil) is processed in the liver so it's not a good choice if you have liver, or even kidney, problems.
  • Not available as a generic.

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Side effects for Nuvigil (Armodafinil)

From clinical trials of Nuvigil / Excessive sleepiness from sleep apnea or shift work ( 1090)

  • HeadacheHeadache17% for Nuvigil vs.9% for placebo
  • Adverse eventsAdverse events7% for Nuvigil vs.4% for placebo
  • NauseaNausea7% for Nuvigil vs.3% for placebo
  • Sleep difficultySleep difficulty5% for Nuvigil vs.1% for placebo
  • DizzinessDizziness5% for Nuvigil vs.2% for placebo
  • DiarrheaDiarrhea4% for Nuvigil vs.2% for placebo
  • Dry mouthDry mouth4% for Nuvigil vs.1% for placebo
  • AnxietyAnxiety4% for Nuvigil vs.1% for placebo
  • Heart pounding or racing sensationHeart pounding or racing sensation2% for Nuvigil vs.1% for placebo
  • ThirstThirst2% for Nuvigil vs.1% for placebo

What to expect when you take Nuvigil (Armodafinil)

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Tips from our pharmacists
  • If using for shift work sleep disorder (SWSD), take Nuvigil (Armodafinil) about an hour before the start of your shift.
  • Taking caffeine with Nuvigil (Armodafinil) can make you feel nervous, shaky, and will raise your heartbeat.
  • If you've been taking Nuvigil (Armodafinil) for a while and decide to stop it, you'll experience withdrawal symptoms if you stop it too fast.
  • Tell your doctor right away if you break out in a rash.
  • Don't drink alcohol with Nuvigil (Armodafinil).

Risks and Warnings for Nuvigil (Armodafinil)

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    • Higher risk if:
    • Taking with alcohol
    • Taking other medicines that make you less alert

    Nuvigil (Armodafinil) lowers your ability to focus, think, and react. Be careful and avoid activities that require you to be alert, such as driving a car or operating machinery, until you know how this medication affects you.

Means that some groups have a high risk of experiencing this side effect

Tips from pharmacists and people taking Nuvigil (Armodafinil)

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The FDA category for this medication is C. It is advised that you: Weigh risks vs. benefits
Pregnancy
Alcohol
  • Tips from our pharmacists
  • Don't drink alcohol with Nuvigil (Armodafinil).
Kidneys & liver
  • Upsides and downsides from our pharmacists
  • Nuvigil (Armodafinil) is processed in the liver so it's not a good choice if you have liver, or even kidney, problems.
  • Risks from our pharmacists
  • Nuvigil (Armodafinil) is processed by the kidney and liver. If you have kidney or liver problems, you may need a different dose, or other medication, to prevent increased risk of side effects.
Sleep
  • Upsides and downsides from our pharmacists
  • Effective in treating excess sleepiness in shift work sleep disorder (SWSD).
  • Doesn't negatively affect daytime sleep.
  • Tips from our pharmacists
  • If using for shift work sleep disorder (SWSD), take Nuvigil (Armodafinil) about an hour before the start of your shift.
  • Great medicine, keeps me awake without overstimulation. I take it for shift work sleep disorder.
    Age: 37
    Gender: Woman
    Taken for: Shift work sleep disorder