Prescription onlyLower-cost generic availableClass: Mental health

Pamelor

(Nortriptyline)

Prescription onlyLower-cost generic availableClass: Mental health
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Improves your mood.

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Our bottom line

Pamelor (Nortriptyline) is a good option for treating depression, especially for people who also have problems with persistent nerve pain.

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Upsides

  • Helpful with treating certain types of pain, like migraines or nerve-related pain.
  • Generally well tolerated and has fewer side effects than other medicines in the same class of drugs.

Downsides

  • Side effects are usually manageable, but can be annoying.
  • Increases the risk of falls, especially when used in the elderly.
  • There's an increased chance of it causing heart problems, especially in people with a history of heart problems.
How it works

Pamelor (Nortriptyline) is a tricyclic antidepressant (TCA). It helps improve your mood by altering the levels of serotonin, norepinephrine, and other similar chemicals in your brain.

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Side effect rates for Pamelor (Nortriptyline)

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These are side effects of Pamelor (Nortriptyline) reported to the FDA by people taking it, and by doctors and pharmacists.
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Risks and Warnings for Pamelor (Nortriptyline)

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    • Higher risk if:
    • Age 24 years or younger

    Pamelor (Nortriptyline) may increase the risk of suicidal thoughts or behavior. Watch for worsening depression or any unusual changes in mood or behavior, especially during the first few months of treatment or when the dose changes. Report anything concerning to a doctor immediately. Pamelor (Nortriptyline) is not approved for use in children younger than age 10.

    This is a black box warning. The FDA requires this warning when there is a significant risk of serious or life-threatening effects that anyone taking the drug should consider.

Means that some groups have a high risk of experiencing this side effect

Common concerns from people taking Pamelor (Nortriptyline)

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Pregnancy
Food
  • Take it with food and/or at bedtime to decrease the potential side effects.