Prescription onlyLower-cost generic availableClass: Gastrointestinal

Protonix Alternatives

(pantoprazole)

Prescription onlyLower-cost generic availableClass: Gastrointestinal
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Compare Protonix (pantoprazole) to alternatives

These medications are comparable to Protonix (pantoprazole) or used for similar purposes.

Protonix
(pantoprazole)

Prilosec
(omeprazole)

Nexium
(esomeprazole)

Prevacid
(lansoprazole)

Zantac 75
(ranitidine)

Pepcid
(famotidine)

Maalox
(aluminum / magnesium / simethicone)

Tums
(calcium carbonate)

Alka-Seltzer Original
(aspirin / citric acid / sodium bicarbonate)

Treats heartburn and excess release of stomach acid. Protonix (pantoprazole) is usually only taken once a day for long-lasting heartburn relief, but it can increase your risk of bone fractures if you've used it for a long time.Treats heartburn and stomach ulcers. Prilosec (Omeprazole) gives you long-lasting heartburn relief. Choose the cheapest proton pump inhibitor because they all work equally well for heartburn.Treats heartburn and stomach ulcers. Nexium (esomeprazole) gives you long-lasting heartburn relief but has some risks if used long term.Treats heartburn and stomach ulcers. Prevacid (lansoprazole) is an effective and inexpensive acid reducer commonly used to provide heartburn relief and help heal ulcers.Relieves heartburn and stomach ulcers. Zantac 75 (ranitidine) is an effective and inexpensive medicine for hearburn with few side effects, but may interfere with other drugs.Relieves heartburn. Pepcid (Famotidine) works well for heartburn but may not last as long or start working as quickly as other antacids.Relieves heartburn and indigestion. Maalox (aluminum / magnesium / simethicone) gives quick relief for heartburn, gas, and bloating, but it may not be as effective or last as long as other antacids.Relieves heartburn. Tums (Calcium carbonate) gives quick relief for heartburn, but does not last all day. Talk to your doctor or pharmacist about other medicines if you need additional relief.Relieves heartburn, headache, and body pains. Alka-Seltzer Original (Aspirin / Citric Acid / Sodium Bicarbonate) gives quick relief for headache, body pains, and upset tummies, but might be hard to swallow if you don't like the taste or fizz.
Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
5.14pantoprazole
Reviews for pantoprazole
68%
of people (All ages) say pantoprazole is worth it
51%
say it works well
13%
say it's a big hassle
584 reviews
Have you used Protonix (pantoprazole)?
Worth itNot sureNot worth it
Reviews for Omeprazole
80%
-12% worse vs. pantoprazole
59%
-8% worse vs. pantoprazole
8%
-5% worse vs. pantoprazole
1167 reviews
Have you used Prilosec (omeprazole)?
Worth itNot sureNot worth it
Reviews for Nexium
75%
-7% worse vs. pantoprazole
59%
-8% worse vs. pantoprazole
11%
-2% worse vs. pantoprazole
1239 reviews
Have you used Nexium (esomeprazole)?
Worth itNot sureNot worth it
Reviews for Prevacid
71%
-3% worse vs. pantoprazole
71%
-20% worse vs. pantoprazole
19%
+6% better vs. pantoprazole
Have you used Prevacid (lansoprazole)?
Worth itNot sureNot worth it
Reviews for Zantac
72%
-4% worse vs. pantoprazole
44%
+7% better vs. pantoprazole
7%
-6% worse vs. pantoprazole
1062 reviews
Have you used Zantac 75 (ranitidine)?
Worth itNot sureNot worth it
Reviews for Pepcid
75%
-7% worse vs. pantoprazole
41%
+10% better vs. pantoprazole
8%
-5% worse vs. pantoprazole
853 reviews
Have you used Pepcid (famotidine)?
Worth itNot sureNot worth it
Reviews for Maalox
69%
-1% worse vs. pantoprazole
30%
+21% better vs. pantoprazole
9%
-4% worse vs. pantoprazole
213 reviews
Have you used Maalox (aluminum / magnesium / simethicone)?
Worth itNot sureNot worth it
Reviews for Tums
82%
-14% worse vs. pantoprazole
43%
+8% better vs. pantoprazole
5%
-8% worse vs. pantoprazole
1373 reviews
Have you used Tums (calcium carbonate)?
Worth itNot sureNot worth it
Reviews for Alka-Seltzer
81%
-13% worse vs. pantoprazole
52%
-1% worse vs. pantoprazole
8%
-5% worse vs. pantoprazole
1055 reviews
Have you used Alka-Seltzer Original (aspirin / citric acid / sodium bicarbonate)?
Worth itNot sureNot worth it
Side effects
pantoprazoleOmeprazoleNexiumPrevacidZantacPepcidMaaloxTumsAlka-Seltzer
  • Headache 3%
  • Diarrhea 4%
  • Vomiting 2%
  • Dizziness 2%
  • Joint pain 2%
More pantoprazole side effects »
  • Upper respiratory infection 75%
  • Fever 33%
  • Headache 7%
  • Abdominal pain 5%
  • Nausea 4%
  • Diarrhea 4%
  • Accidental injuries 4%
  • Flatulence 3%
  • Vomiting 3%
More Omeprazole side effects »

The Nexium FDA package insert doesn’t have numbers about how common side effects are.

More about Nexium side effects »
  • Diarrhea 2%
  • Abdominal pain 1%
More Prevacid side effects »

The Zantac FDA package insert doesn’t have numbers about how common side effects are.

More about Zantac side effects »
  • Headache 5%
  • Diarrhea 2%
More Pepcid side effects »

The Maalox FDA package insert doesn’t have numbers about how common side effects are.

More about Maalox side effects »

We haven’t found good data for Tums side effects.

FDA side effect reports for Tums »

We haven’t found good data for Alka-Seltzer side effects.

FDA side effect reports for Alka-Seltzer »
How it works
pantoprazoleOmeprazoleNexiumPrevacidZantacPepcidMaaloxTumsAlka-Seltzer
Protonix (pantoprazole) is a proton pump inhibitor. It lowers the amount of acid in your stomach which treats heartburn.Prilosec (Omeprazole) is a proton pump inhibitor (PPI). It lowers the amount of acid in your stomach, treats heartburn, and heals ulcers.Nexium (esomeprazole) is a proton pump inhibitor (PPI). It treats heartburn and heals ulcers by lowering the amount of acid in your stomach.Prevacid (lansoprazole) is a proton pump inhibitor (PPI). It lowers the amount of acid in your stomach by blocking the final step of stomach acid production.Zantac 75 (ranitidine) reduces the production of acid by blocking a chemical from acting on the acid-producing cells in your stomach.Pepcid (Famotidine) is a type of antacid called an H2 blocker. It blocks the chemical histamine, which lowers acid production in your stomach. This treats heartburn and helps ulcers heal.Maalox (aluminum / magnesium / simethicone) is a combination medicine for heartburn and indigestion. Aluminum and magnesium are antacids that treat heartburn and indigestion. Simethicone relieves gas and bloating.Tums (Calcium carbonate) is an antacid. It relieves heartburn and indigestion by neutralizing stomach acid.Alka-Seltzer Original (Aspirin / Citric Acid / Sodium Bicarbonate) is a combination medicine. Sodium bicarbonate is an antacid that relieves heartburn and acid tummy (indigestion). Aspirin is a pain reliever that treats headache and body pains.
Type of medication
pantoprazoleOmeprazoleNexiumPrevacidZantacPepcidMaaloxTumsAlka-Seltzer
Prescription onlyPrescription or OTCOver-the-counterPrescription or OTCPrescription or OTCPrescription or OTCOver-the-counterOver-the-counterOver-the-counter
Available as
pantoprazoleOmeprazoleNexiumPrevacidZantacPepcidMaaloxTumsAlka-Seltzer
  • Pill
  • Packet
  • Extended release
  • Pill
  • Injection
  • Packet
  • Extended release
  • Dissolving tablet extended release
  • Liquid
  • Pill
  • Oral solution
  • Oral syrup
  • Injection
  • Pill
  • Chewable tablet
  • Liquid
  • Chewable tablet
  • Liquid
  • Chewable tablet
  • Liquid
  • Chewable tablet
  • Effervescent tablet
Used for
pantoprazoleOmeprazoleNexiumPrevacidZantacPepcidMaaloxTumsAlka-Seltzer
  • GERD
  • H Pylori Bacterial Infection
Risk factors for serious side effects
pantoprazoleOmeprazoleNexiumPrevacidZantacPepcidMaaloxTumsAlka-Seltzer
  • Using multiple daily doses and/or for 1 year or longer
  • People age 65 or older
  • High risk of bone fractures
  • People who are being treated in the hospital
  • People with lupus
Detailed Protonix (pantoprazole) risks & warnings »
  • Helicobacter pylori infection
  • Autoimmune disease
  • Being hospitalized
  • Antibiotic use
  • Osteoporosis
Detailed Prilosec (omeprazole) risks & warnings »
  • Being treated at a hospital
  • High dose Nexium (esomeprazole)
  • Long-term treatment with Nexium (esomeprazole)
  • Low bone mineral density
  • Aged 65 years or older
Detailed Nexium (esomeprazole) risks & warnings »
  • High dose Prevacid (lansoprazole)
  • Long-term treatment with Prevacid (lansoprazole)
  • Low bone mineral density
  • Older age
Detailed Prevacid (lansoprazole) risks & warnings »
  • Aged 60 years or older
  • Kidney conditions
  • Liver conditions
  • Acute Porphyria
  • Asthma
Detailed Zantac 75 (ranitidine) risks & warnings »
  • Current kidney disease
Detailed Pepcid (famotidine) risks & warnings »
  • Kidney problems
  • Taking more than the recommended daily maximum
Detailed Maalox (aluminum / magnesium / simethicone) risks & warnings »
    Coming soon.
    • Current kidney disease
    • Kidney dialysis
    • Age 65 or older
    • Congestive heart failure (CHF)
    • High blood pressure
    Detailed Alka-Seltzer Original (aspirin / citric acid / sodium bicarbonate) risks & warnings »
    Pregnancy

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

    The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

    Price
    pantoprazoleOmeprazoleNexiumPrevacidZantacPepcidMaaloxTumsAlka-Seltzer
    No price related info.No price related info.No price related info.
    • Prevacid (lansoprazole) is available over-the-counter and as inexpensive, generic options.
    No price related info.No price related info.No price related info.No price related info.No price related info.
    Interactions
    pantoprazoleOmeprazoleNexiumPrevacidZantacPepcidMaaloxTumsAlka-Seltzer
    No interactions related info.
    • Avoid drug interactions by telling your doctor all of the other medications or herbal supplements you take before starting Omeprazole.
    • Can interact with other drugs so be sure your doctor knows all the medicine you're taking before starting Omeprazole.
    • Since some prescription drugs can interact with Nexium (esomeprazole), talk to your doctor about all the medicines that you're taking.
    • Some prescription drugs can interact with Prevacid (lansoprazole), so talk to your doctor or pharmacist about the medicines you are taking.
    • Zantac 75 (ranitidine) can interact with certain prescription and over-the-counter medications. Let your doctor or pharmacist know about the medicines you are currently taking.
    • Few drug interactions.
    No interactions related info.No interactions related info.No interactions related info.
    Alcohol
    pantoprazoleOmeprazoleNexiumPrevacidZantacPepcidMaaloxTumsAlka-Seltzer
    No alcohol related info.No alcohol related info.No alcohol related info.No alcohol related info.
    • The syrup product may contain up to 7.5% of alcohol.
    No alcohol related info.No alcohol related info.No alcohol related info.No alcohol related info.
    Food
    pantoprazoleOmeprazoleNexiumPrevacidZantacPepcidMaaloxTumsAlka-Seltzer
    • Unlike other proton pump inhibitors, it can be taken with or without food and have the same effectiveness.
    • Take 1 hour before a meal.
    No food related info.No food related info.No food related info.No food related info.
    • Talk to your doctor or pharmacist about foods to avoid that can help prevent heartburn.
    No food related info.
    • Take it with food to lower the chance of an upset stomach.
    Kidneys and liver
    pantoprazoleOmeprazoleNexiumPrevacidZantacPepcidMaaloxTumsAlka-Seltzer
    • Protonix (pantoprazole) can very rarely damage your kidneys. This can happen at any time. Talk to your doctor right away if you are urinating less or have blood in the urine.
    No kidneys and liver related info.
    • Nexium (esomeprazole) can cause acute kidney damage that can occur at any time during treatment. If you notice blood in the urine, changes in urine output, swelling of the body, weight gain, fever, or confusion, stop taking Nexium (esomeprazole) and speak to your doctor immediately.
    • Prevacid (lansoprazole) can cause acute kidney damage that can occur at any time during treatment. Stop taking Prevacid (lansoprazole) and speak to your doctor immediately if you notice blood in the urine, changes in urine output, swelling of the body, weight gain, fever, or confusion.
    No kidneys and liver related info.
    • Because Pepcid (Famotidine) is processed by the kidney it can cause some worrisome side effects for people with kidney problems. These include confusion, delirium, and a dangerous irregular heartbeat known as QT prolongation. If you have kidney problems, you may need a different dose to prevent this increased risk for side effects.
    • Can cause more serious side effects for people with kidney disease. Ask your doctor to give you a lower dose or choose a different option.
    • Maalox (aluminum / magnesium / simethicone) contains aluminum and magnesium that can build up in your kidneys if you have kidney problems which can be dangerous. Talk to your doctor or pharmacist before taking Maalox (aluminum / magnesium / simethicone) to see if it is right for you. Don't take more than the maximum amount per day as shown on the label.
    • May increase calcium levels too much in people with kidney or thyroid conditions.
    • If you have kidney or hyperparathyroid disease Alka-Seltzer Original (Aspirin / Citric Acid / Sodium Bicarbonate) can build up in your blood. This may can cause toxic levels of sodium in your body. This is more likely if you have severe kidney disease (defined as a kidney function blood test called GFR of less than 30ml/min). If you have severe kidney disease or are on kidney dialysis don't use Alka-Seltzer Original (Aspirin / Citric Acid / Sodium Bicarbonate); a different antacid would be better for you.
    Pain
    pantoprazoleOmeprazoleNexiumPrevacidZantacPepcidMaaloxTumsAlka-Seltzer
    • Talk to your doctor if you get watery diarrhea, fever, or stomach pain that don't go away after taking Protonix (pantoprazole), which can happen even 2 months after stopping the medicine.
    No pain related info.No pain related info.No pain related info.No pain related info.No pain related info.No pain related info.No pain related info.No pain related info.
    Upsides and benefits
    pantoprazoleOmeprazoleNexiumPrevacidZantacPepcidMaaloxTumsAlka-Seltzer
    • Most people can take Protonix (pantoprazole) without any noticeable day-to-day side effects.
    • Protonix (pantoprazole) lasts longer than other types of antacids (like Zantac, Pepcid, or Tums), and you only need to take it once or twice a day.
    • You can take it with a quick-acting antacid (like Maalox or Tums) if you need relief right away.
    • Unlike other proton pump inhibitors, it can be taken with or without food and have the same effectiveness.
    • Can be used in children age 5 or older.
    • Most people can take Omeprazole without any noticeable day-to-day side effects.
    • Omeprazole lasts longer than other types of antacids (like Zantac, Pepcid, or Tums), and you only need to take it once or twice a day.
    • You can take it in combination with a quick-acting antacid (like Maalox or Tums) if you need relief right away.
    • In studies it was better than a placebo (sugar pill) and as good as other proton pump inhibitors at treating heartburn.
    • Available as both a generic and over-the-counter option, so it's pretty affordable.
    • Most people can take Nexium (esomeprazole) without any noticeable day-to-day side effects.
    • Nexium (esomeprazole) lasts longer than other types of antacids (like Zantac, Pepcid, or Tums), and you only need to take it once a day.
    • You can take it in combination with a quick-acting antacid (like Maalox or Tums) if you need quicker relief.
    • Nexium (esomeprazole) is inexpensive, with over-the-counter and generic options.
    • Coupons are available for the brand name - speak to your doctor or pharmacist.
    • The packet form is a good option if you have trouble swallowing pills.They can be mixed with water for easier swallowing.
    • Most people can take Prevacid (lansoprazole) without any noticeable day-to-day side effects.
    • Comes in a dissolving tablet to be placed on the tongue if you cannot or do not like to swallow pills.
    • Prevacid (lansoprazole) lasts longer than other types of antacids (like Zantac, Pepcid, or Tums), and you only need to take it once a day.
    • You can take it in combination with a quick-acting antacid (like Maalox or Tums) if you need relief right away.
    • Prevacid (lansoprazole) is available over-the-counter and as inexpensive, generic options.
    • Zantac 75 (ranitidine) works well to relieve heartburn symtoms and is quite tolerable.
    • You can take it in combination with a quick-acting antacid (like Maalox or Tums) if you need relief right away.
    • If you have trouble swallowing pills you may find the liquid product a good option.
    • Inexpensive with over-the-counter and generic options.
    • Coupons are available for the brand product - speak to your doctor or pharmacist.
    • Most people can take Famotidine without any noticeable day-to-day side effects.
    • Famotidine lasts longer than many other antacids like Maalox and Tums, and you only need to take it once or twice a day.
    • You can take it in combination with a quick-acting antacid (like Maalox or Tums) if you need relief right away.
    • Available as both a generic and over-the-counter option, so it's pretty affordable.
    • Few drug interactions.
    • Works quickly.
    • Inexpensive and available over-the-counter.
    • Is one of the first choice medications for heartburn relief if you are pregnant.
    • Tums (Calcium carbonate) is an effective, first-line medication for hearburn.
    • Tums (Calcium carbonate) starts working in seconds.
    • Has minimal side effects.
    • Available in chewable form.
    • Is inexpensive and readily available over-the-counter.
    • Coupons are available – speak to your doctor or pharmacist.
    • Works great if you have an upset stomach and a headache or body pain at the same time.
    • Works really fast.
    • Available over the counter without a prescription.
    • Cheap.
    Downsides and risks
    pantoprazoleOmeprazoleNexiumPrevacidZantacPepcidMaaloxTumsAlka-Seltzer
    • Doesn't start working as fast as some other antacids like Tums, Rolaids, or Maalox.
    • Needs to be taken every single day for a certain period of time to be effective.
    • Like with other proton pump inhibitors, long-term use can cause weak or broken bones.
    • Only available as a prescription medicine, not over the counter.
    • Can lower the magnesium level in your body so you may need to take a supplement for it.
    • Doesn't start working as fast as some other antacids like Tums, Rolaids, or Maalox.
    • Like with other proton pump inhibitors, long-term use can cause weak or broken bones.
    • Can cause low levels of magnesium in the blood. You might need to take a magnesium supplement if you use Omeprazole long-term.
    • Although the generic is affordable, other medications might still be cheaper than Omeprazole.
    • Can interact with other drugs so be sure your doctor knows all the medicine you're taking before starting Omeprazole.
    • Doesn't start working right away like antacids (Tums, Rolaids, or Maalox).
    • It can take several days or weeks to start feeling benefits.
    • May not be the best choice for patients 65 years of age and older due to risk of bone fractures and severe diarrhea.
    • Doesn't start working right away like some other acid reducers (Tums, Rolaids, or Maalox).
    • May not be the best choice for patients 65 years of age and older due to risk of bone fractures and C. diff infection (bacterial).
    • Is used if you have frequent heartburns that occur more than 2 days per week. Speak to your doctor or pharmacist if you only have occasional heartburn.
    • Zantac 75 (ranitidine) doesn't work as quickly as some other acid reducers. Speak to your doctor or pharmacist if you need quicker relief.
    • Zantac 75 (ranitidine) does not last as long as some other acid reducers. Speak to your doctor or pharmacist if you need longer relief.
    • May not be as effective in healing the esophagus when it is inflammed or torn, known as erosive esophagitis. Your doctor will assess which medication is best for you.
    • Can lower your vitamin B12 levels if you use Zantac 75 (ranitidine) for a long time. Your doctor can order lab tests to monitor your vitamin B12 levels.
    • Other antacids like Maalox, Tums, or Rolaids often start to work more quickly than Famotidine.
    • Medication like omeprazole (proton pump inhibitors) works better at healing and preventing stomach ulcers than medication like Famotidine (H2 blockers).
    • Can cause more serious side effects for people with kidney disease. Ask your doctor to give you a lower dose or choose a different option.
    • Doesn't last very long. Talk to your doctor or pharmacist if you need longer lasting relief.
    • Is not a good option if you have frequent symptoms (more than 2 times a week). Talk to your doctor or pharmacist about stronger medications.
    • Because Tums (Calcium carbonate) only lasts for 1 to 2 hours, you may need additional doses.
    • May increase calcium levels too much in people with kidney or thyroid conditions.
    • May have a chalky taste.
    • Doesn't last very long.
    • Other antacids like Zantac (H2 blockers) and omeprazole (proton pump inhibitors) can work better and last longer.
    • Because it has aspirin in it, it increases the risk of bleeding, especially if you take any other blood thinning medicine.
    • Can't be used by people with allergy to aspirin.
    • You may not like the taste or fizz.
    Tips from our pharmacists for people taking the medication
    pantoprazoleOmeprazoleNexiumPrevacidZantacPepcidMaaloxTumsAlka-Seltzer
    • Take the tablet form of Protonix (pantoprazole) with or without food.
    • The medicine should be swallowed whole and not to to be chewed or crushed.
    • Protonix (pantoprazole) takes some time to kick in, about 2.5 hours after taking it.
    • The oral suspension form needs to be prepared and then taken 30 minutes before a meal. The contents of the packet for the suspension shouldn't be crushed or chewed and be taken in apple juice or applesauce only as stated in the instructions.
    • Talk to your doctor if you get watery diarrhea, fever, or stomach pain that don't go away after taking Protonix (pantoprazole), which can happen even 2 months after stopping the medicine.
    • Using this medicine for a long period of time can increase your risk of getting weaker bones. Talk to your doctor if you are worried about this possible long-term side effect.
    • Take 1 hour before a meal.
    • Don't chew or crush capsules; swallow them whole.
    • If you have trouble swallowing you can carefully open the capsules and sprinkle the inside pellets onto applesauce. Swallow the applesauce without chewing or crushing the pellets.
    • When using Omeprazole long-term, take a calcium citrate with vitamin D supplement daily to prevent bone loss. Be sure it's calcium citrate because it works the best when using a proton pump inhibitor.
    • Get a blood test for your magnesium level once a year; you may need a magnesium supplement while using Omeprazole.
    • Avoid drug interactions by telling your doctor all of the other medications or herbal supplements you take before starting Omeprazole.
    • Take Nexium (esomeprazole) with a full glass of water 1 hour before eating.
    • Starts working in as little as an hour.
    • It can take 1 to 4 days to take full effect.
    • Since some prescription drugs can interact with Nexium (esomeprazole), talk to your doctor about all the medicines that you're taking.
    • Do not take Nexium (esomeprazole) for more than 14 days, unless directed by your doctor. Speak to your doctor if your symptoms don't go away after 2 weeks.
    • Nexium (esomeprazole) capsules can be opened and sprinkled on 1 tablespoon of applesauce, cottage cheese, or yogurt. Swallow immediately after.
    • Take Prevacid (lansoprazole) with a full glass of water before eating.
    • Starts working in 1 to 3 hours. It can take 1 to 4 days to take full effect.
    • Some prescription drugs can interact with Prevacid (lansoprazole), so talk to your doctor or pharmacist about the medicines you are taking.
    • Do not take for more than 14 days, unless directed by your doctor. Speak to your doctor if your symptoms don't go away after 2 weeks.
    • Prevacid (lansoprazole) capsules can be opened and sprinkled on 1 tablespoon of applesauce, cottage cheese, or yogurt. Swallow immediately after. The dissolving tablets shouldn't be swallowed, broken, or chewed.
    • To prevent a heartburn attack, take Zantac 75 (ranitidine) 30 minutes before eating.
    • Works within 30 to 60 minutes. Relief lasts up to 12 hours.
    • Do not use Zantac 75 (ranitidine) for more than 14 days. Talk to your doctor if your symptoms do not improve after 2 weeks of using the over-the-counter product, as this may indicate a more serious problem.
    • The syrup product may contain up to 7.5% of alcohol.
    • Speak to your doctor or pharmacist about lifestyle and dietary changes that can help prevent heartburn.
    • Short-term treatment of ulcers and acid reflux.
    • Starts working within minutes, and lasts for 1-2 hours.
    • If you are using the liquid product, shake well before using.
    • Don't take more than the recommended amount per day on the package. If you need to take this for more than 2 weeks, talk to your doctor.
    • People on a magnesium-restricted diet may need to avoid Maalox. Ask your doctor.
    • Talk to your doctor or pharmacist about foods to avoid that can help prevent heartburn.
    • Eating smaller portion sizes and not eating 3 hours before bedtime can help prevent heartburn.
    • Take at the first sign of discomfort.
    • You may need to separate Tums (Calcium carbonate) from some medicines to avoid interactions. Talk to your doctor or pharmacist about all the medicines you're taking, including prescription, supplements, and over the counter medicines.
    • Eating smaller, more frequent meals can help alleviate some symptoms of heartburn.
    • Certain spicy or fatty foods increase your risk of heartburn. Talk to your doctor or pharmacist to find out which foods you should avoid.
    • Avoiding eating 3 hours before bedtime can also help prevent heartburn.
    • If heartburn doesn't improve or lasts more than 2 weeks, talk to your doctor.
    • Don't take Alka-Seltzer if you're allergic to aspirin.
    • Take it with food to lower the chance of an upset stomach.
    • This medicine isn't recommended for kids 12 and younger because it has aspirin in it.
    • Stop taking this right away and talk to your doctor if you have ringing in your ears, rash, trouble breathing, unusual bleeding, or nausea or vomiting that doesn't go away.
    • Having a dental or medical procedure? You may need to stop taking this before the big day. Ask your dentist or doctor.
    • Alka-Seltzer contains sodium. If you need to follow a low sodium diet a different medication would be better for you.
    • Not a good choice if you have stomach bleeding, bleeding problems, diabetes, or gout, or if you're taking medicines to thin your blood.
    Learn more
    More about pantoprazoleSide effectsReviews & ratingsAlternativesFDA package insert
    Have you used Protonix (pantoprazole)?
    Worth itNot sureNot worth it
    More about OmeprazoleSide effectsReviews & ratingsFDA package insert
    Have you used Prilosec (omeprazole)?
    Worth itNot sureNot worth it
    More about NexiumSide effectsReviews & ratingsFDA package insert
    Have you used Nexium (esomeprazole)?
    Worth itNot sureNot worth it
    More about PrevacidSide effectsReviews & ratingsFDA package insert
    Have you used Prevacid (lansoprazole)?
    Worth itNot sureNot worth it
    More about ZantacSide effectsReviews & ratingsFDA package insert
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