Prescription onlyLower-cost generic availableClass: Mental health

Paxil 

(paroxetine)

Prescription onlyLower-cost generic availableClass: Mental health
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Improves mood and helps you relax.

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Our bottom line

Paxil (Paroxetine) is good for treating depression and anxiety but it causes more weight gain, sleepiness, and withdrawal symptoms than other antidepressants.

Price and discounts
Best available price for 30 (20mg) tablets of paroxetine

Upsides

  • Effective at relieving depression and anxiety symptoms.
  • Lowers relapse rates of depression and anxiety disorders, including OCD, panic disorder, social anxiety disorder, and generalized anxiety disorder.
  • It causes drowsiness, so it's good for people who have trouble sleeping.
  • Can cause weight gain, which can be helpful if you've recently lost weight or have a low appetite.
  • Six out of ten people who use an antidepressant for the first time find that it works for them.
People say this drug is:
694 reviews

Downsides

  • Can cause more sexual side effects like low libido and an inability to orgasm or ejaculate than most antidepressants.
  • More likely to cause minor weight gain (1 to 5 pounds) or make you feel sick if you miss a dose than other antidepressants.
  • Can harm an unborn child, so you can't take it if you're pregnant.
  • Like most antidepressants, it can cause a higher risk of suicidal thoughts and behavior for people younger than age 24.
  • The first antidepressant you try doesn't always work or it can cause side effects you really don't like. You might need to try a few different medications until you find one that works for you.
How it works

Paxil (Paroxetine) is a selective serotonin reuptake inhibitor (SSRI) antidepressant. It increases serotonin activity in the brain, which regulates mood.

What to expect when you take Paxil (paroxetine) for Depression

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Side effect rates for Paxil (paroxetine)

3162 From clinical trials of Paxil / Females only
  • Decreased libido
  • Difficulty reaching orgasm

Risks and Warnings for Paxil (paroxetine)

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    • Higher risk if:
    • Age 24 years or younger

    Paxil (Paroxetine) may increase the risk of suicidal thoughts or behavior. Watch for worsening depression or any unusual changes in mood or behavior, especially during the first few months of treatment or when the dose changes. Report anything concerning to a doctor immediately. Paxil (Paroxetine) is not approved for use in children younger than age 18.

    This is a black box warning. The FDA requires this warning when there is a significant risk of serious or life-threatening effects that anyone taking the drug should consider.

Means that some groups have a high risk of experiencing this side effect

Common concerns from people taking Paxil (paroxetine)

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Pregnancy
Price
  • The discontinuation syndrome was awful. "Zaps" throughout my body and nausea for months.
Alcohol
  • If you have any history of drug or alcohol abuse, you are likely to relapse, and make other horrible decisions, as this prescription distorts reality and makes you think nothing matters, or that there are no consequences for poor choices. By the time you try to come off it, the damage is done, and you will go through weeks of hell trying to wean yourself off because the withdrawal symptoms are horrendous. This drug is banned in many countries, for obvious reasons.
Food
  • Take with food to avoid upset stomach.
Sex
  • Made orgasms more difficult, but saved me from crippling panic attacks. Worth it, but only if you really need to be on it.
  • no ability to orgasm, horrible withdrawal after 1 day
Sleep
  • It causes drowsiness, so it's good for people who have trouble sleeping.
  • I take it in the morning. I sleep very well. I only take 10 MG. I seemed to have no side effects. It have taken the edge off for me. I feel great.
  • I hate the drowsiness, lack of motivation and general apathy toward life.
  • Prepare to sleep ALLLLLLLLLLL the time..
Weight
  • Can cause weight gain, which can be helpful if you've recently lost weight or have a low appetite.
  • More likely to cause minor weight gain (1 to 5 pounds) or make you feel sick if you miss a dose than other antidepressants.
  • Outrageous weight gain - no problems like that with other antidepressants. Difficult to get off. Try something else unless this is a necessity.
  • Experienced weight gain, high blood pressure and trouble sleeping. I ate healthy and balanced. I also worked out 5 days a week and still could not lose weight.
  • Caused weight gain.