Sudafed Pe

Skip to: what to expect sectionSkip to: side effects sectionSkip to: risks and warnings sectionSkip to: common concerns from users and pharmacists
4.18Phenylephrine

Clears your sinuses.

Skip Upsides & Downsides section. Skip to side effects section.

Our bottom line

Sudafed Pe (Phenylephrine) is a good medication for relieving stuffy nose. It doesn't work as well as pseudoephedrine (Sudafed), but it has fewer side effects.

Quick facts about Phenylephrine
  • Drug class: Respiratory
  • Rx status: Prescription or OTC
  • Generic status: Generic only
Prices and discounts
Lowest price for 2 2ml of 2.5% eye droppers
Determining your location...
$12.53

Upsides

  • Works to clear nasal congestion and helps you breathe better.
  • Helpful in relieving congestion-related headaches.
  • Has fewer side effects than other decongestants like pseudoephedrine.
  • It doesn't raise your blood pressure and heart rate as much, or cause as much trouble falling asleep.
  • Doesn't give you rebound congestion (worse symptoms when you stop taking it) like nasal spray decongestants do.
People’s experience with Phenylephrine

164reviews so far. What do you think?

Worth itNot sureNot worth it

Downsides

  • Phenylephrine doesn't last as long as other decongestants like pseudoephedrine (Sudafed).
  • You shouldn't use it if you have high blood pressure.
  • Can make your heart race or make you feel anxious and restless.
  • Shouldn't use it before you want to sleep.
  • Not as effective after using it for 4 days in a row.
How it works

Sudafed Pe (Phenylephrine) is a decongestant. It narrows blood vessels and reduces swelling in your nasal passages to make breathing easier.

Quick facts about Phenylephrine
  • Drug class: Respiratory
  • Rx status: Prescription or OTC
  • Generic status: Generic only

Used for

Dosage forms

  • Pill
  • Nasal spray
  • Eye drops
  • Suppository
People’s experience with Phenylephrine

164reviews so far. What do you think?

Worth itNot sureNot worth it
Skip side effects section. Skip to risks and warnings section.

Side effect rates for Sudafed Pe (Phenylephrine)

0 reports
These are side effects of Sudafed Pe (Phenylephrine) reported to the FDA by people taking it, and by doctors and pharmacists.
Filter group. All currently selected
Filter group. All currently selected

Risks and Warnings for Sudafed Pe (Phenylephrine)

Skip risks section. Skip to common concerns section.
    • Higher risk if:
    • History of high blood pressure
    • Taking MAO inhibitors

    People taking Sudafed Pe (Phenylephrine) and MAO inhibitors together, or up to 14 days apart from each other, can experience very high blood pressure that can cause headaches and strokes. MAOI drugs are used to treat Parkinson's disease, depression, and other emotional conditions. Talk to your doctor or pharmacist if you're taking MAO inhibitors and still want to use a cough medicine.

Common concerns from people taking Sudafed Pe (Phenylephrine)

Final section. Do you want to return to drug navigation?
Pregnancy