Plaquenil

(hydroxychloroquine)

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Treats malaria and autoimmune conditions including rheumatoid arthritis and lupus.

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Our bottom line

Plaquenil (hydroxychloroquine) is an effective medication for autoimmune conditions and malaria that comes with less side effects than other DMARDs.

Quick facts about Plaquenil
  • Drug class: Autoimmune
  • Rx status: Prescription only
  • Generic status: Lower-cost generic available (hydroxychloroquine)
Prices and discounts
Lowest price for 60 200mg tablets
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$35.15
  • Price before coupon
    $243.24
  • Lowest price with coupon
    $35.15
    86% savings

Upsides

  • Plaquenil (hydroxychloroquine) has been shown to improve physical function in up to 80% of patients with rheumatoid arthritis. Plaquenil (hydroxychloroquine) is commonly used for lupus in children because of less side effects compared to other medications.
  • Plaquenil (hydroxychloroquine) helps minimize joint damage. It can also decrease symptoms and future complications.
  • Plaquenil (hydroxychloroquine) is a good choice for people who have difficulty tolerating newer biologic medications.
  • A generic form of Plaquenil (hydroxychloroquine) is available.

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What to expect from Plaquenil, on one page

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Downsides

  • You will likely have to take additional medications to keep your rheumatoid arthritis in control.
  • Some people may develop eye problems, so you’ll have to get your eyes checked often.
  • Depending on what you're being treated for, it can take up to 6 months for the full benefits of Plaquenil (hydroxychloroquine).
  • Many people have nausea, stomach cramps, and diarrhea when they first start taking Plaquenil (hydroxychloroquine).
  • If you have heart, eye, liver conditions, or psoriasis, talk to your doctor to see if Plaquenil (hydroxychloroquine) is right for you.

Get the newsletter!

Sign up and get Pill Talk, the latest in health & medicine news from Iodine

Get our free fact sheet

What to expect from Plaquenil, on one page

Download Fact Sheet
Prices and discounts
Lowest price for 60 200mg tablets
Determining your location...
$35.15
  • Price before coupon
    $243.24
  • Lowest price with coupon
    $35.15
    86% savings
How it works

Plaquenil (hydroxychloroquine) belongs to a group of drugs called DMARDs (disease-modifying anti-rheumatic drug).It calms your immune system and blocks the functioning of parasites responsible for malaria.

Quick facts about Plaquenil
  • Drug class: Autoimmune
  • Rx status: Prescription only
  • Generic status: Lower-cost generic available (hydroxychloroquine)

Dosage forms

  • Pill
Tried Plaquenil? Write a review!

What to expect when you take Plaquenil (hydroxychloroquine) for Rheumatoid arthritis

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Side effect rates for Plaquenil (hydroxychloroquine)

Risks and Warnings for Plaquenil (hydroxychloroquine)

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  • Doctors should be completely familiar with the medication label before prescribing Plaquenil (hydroxychloroquine).

    This is a black box warning. The FDA requires this warning when there is a significant risk of serious or life-threatening effects that anyone taking the drug should consider.

Means that some groups have a high risk of experiencing this side effect

Common concerns from people taking Plaquenil (hydroxychloroquine)

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Interactions
  • Certain medications can interact with Plaquenil (hydroxychloroquine), so to be safe, tell your doctor about other medications and supplements you may be taking.
Alcohol
  • Don't drink alcohol while taking Plaquenil (hydroxychloroquine). Alcoholic drinks can lead to liver problems while taking Plaquenil (hydroxychloroquine).
Food
  • Take Plaquenil (hydroxychloroquine) with food or milk to help decrease nausea. Do not break or crush the pills.
  • Reviewed Plaquenilon 3/16/2017Eat with food to help prevent stomach upset
    29
    Woman
    Two years or more
    Rheumatoid arthritis
  • Reviewed Plaquenilon 8/26/2017Take it with food just before bed so you sleep through the worst of the side effects
    27
    Woman
    Two years or more
Kidneys and liver
  • If you have heart, eye, liver conditions, or psoriasis, talk to your doctor to see if Plaquenil (hydroxychloroquine) is right for you.
Pain
  • Reviewed Plaquenilon 5/5/2017This medicine has worked well for me however, I do have some side effects that are not as bad as the pain. Tinitis and headaches
    59
    Man
    Two years or more
    Rheumatoid arthritis