Prescription onlyLower-cost generic availableClass: Autoimmune

PlaquenilAlternatives

(hydroxychloroquine)

Prescription onlyLower-cost generic availableClass: Autoimmune
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Compare Plaquenil (hydroxychloroquine) to alternatives

These medications are comparable to Plaquenil (hydroxychloroquine) or used for similar purposes.

Plaquenil
(hydroxychloroquine)

Rituxan
(rituximab)

Humira
(adalimumab)

Cimzia
(certolizumab)

Enbrel
(etanercept)

Orencia
(abatacept)

Arava
(leflunomide)

Actimmune
(tocilizumab)

Otrexup
(methotrexate)

Remicade
(infliximab)

Improves inflammatory conditions like rheumatoid arthritis. Plaquenil (Hydroxychloroquine) is a great medication for rheumatoid arthritis and comes with less side effects than other DMARDs.Calms down your immune system. Rituxan (Rituximab) is effective for treating multiple types of cancer and arthritis. That said, you'll need to watch for possibly serious side effects, especially infusion reactions.Calms down the immune system. Humira (adalimumab) is good for treating many autoimmune conditions, but it can also cause serious side effects.Reduces inflammation. Cimzia (Certolizumab) is an effective medicine to calm down your immune system, but it can be expensive and it requires a lot of monitoring while you're taking it.Calms down your immune system. Enbrel (Etanercept) is very effective at calming down your immune system, but it's expensive, you have to take into account the hassle of injections and traveling with the medication.Orencia (Abatacept) decreases inflammation in rheumatoid arthritis. Orencia (Abatacept) slows the progress of rheumatoid arthritis, but can also have serious side effects.Coming soon.Calms down the immune system and helps prevent joint damage. Actimmune (tocilizumab) effectively relieves pain and prevents joint damage. You can get it as a shot or an infusion, but it may not be the best choice if you have liver problems.Treats cancer and changes how your immune system works. Otrexup (Methotrexate) is a first line treatment for many autoimmune diseases and types of cancer. If you're taking it for a long time, you'll have to get routine blood tests.Calms down your immune system. Remicade (Infliximab) is very effective at calming down your immune system, but you have to get each dose at your doctor's office and watch out for serious side effects.
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Reviews & ratings
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Not enough reviews for this drug. Help someone out, leave a review!

Have you used Plaquenil (hydroxychloroquine)?
Worth itNot sureNot worth it

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Have you used Rituxan (rituximab)?
Worth itNot sureNot worth it
Reviews for Humira (adalimumab)
60%
-33% worse vs. Plaquenil (hydroxychloroquine)
51%
-20% worse vs. Plaquenil (hydroxychloroquine)
26%
-5% worse vs. Plaquenil (hydroxychloroquine)
182 reviews
Have you used Humira (adalimumab)?
Worth itNot sureNot worth it

Not enough reviews for this drug. Help someone out, leave a review!

Have you used Cimzia (certolizumab)?
Worth itNot sureNot worth it
Reviews for Enbrel (etanercept)
62%
-31% worse vs. Plaquenil (hydroxychloroquine)
53%
-18% worse vs. Plaquenil (hydroxychloroquine)
17%
+4% better vs. Plaquenil (hydroxychloroquine)
Have you used Enbrel (etanercept)?
Worth itNot sureNot worth it

Not enough reviews for this drug. Help someone out, leave a review!

Have you used Orencia (abatacept)?
Worth itNot sureNot worth it

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Have you used Arava (leflunomide)?
Worth itNot sureNot worth it

Not enough reviews for this drug. Help someone out, leave a review!

Have you used Actimmune (tocilizumab)?
Worth itNot sureNot worth it

Not enough reviews for this drug. Help someone out, leave a review!

Have you used Otrexup (methotrexate)?
Worth itNot sureNot worth it
Reviews for Remicade (infliximab)
76%
-17% worse vs. Plaquenil (hydroxychloroquine)
62%
-9% worse vs. Plaquenil (hydroxychloroquine)
15%
+6% better vs. Plaquenil (hydroxychloroquine)
Have you used Remicade (infliximab)?
Worth itNot sureNot worth it
Side effects
PlaquenilRituxanHumiraCimziaEnbrelOrenciaAravaActemraMethotrexateRemicade

We haven’t found good data for Plaquenil side effects.

FDA side effect reports for Plaquenil »
  • Fever 60%
  • Lung disorder 31%
  • Cardiac disorder 28%
  • Chills 13%
  • Any infection 62%
  • Infusion reaction 12%
  • Any serious infection 11%
  • Cardiac side effect 1%
  • Tested positive for haca 23%
More Rituxan side effects »
  • Upper airway infection 4%
  • Rash 6%
  • Headache 4%
  • Sinus infection 2%
  • Nausea 1%
  • Injection site reactions 7%
  • Urinary tract infection 3%
  • Flu syndrome 1%
  • Stomach pain 3%
  • High cholesterol 2%
More Humira side effects »
  • Any side effect 1%
  • Upper respiratory infections 7%
  • Urinary tract infections 1%
  • Joint pain 2%
  • Ear, nose, or throat infection 4%
  • Headache 1%
  • High blood pressure 3%
  • Common cold 4%
  • Back pain 3%
  • Fever 1%
More Cimzia side effects »
  • Positive anti-double-stranded dna antibodies 11%
  • Antibodies to etanercept 6%
  • Crithidia luciliae 3%
  • Anticardiolipin 3%
  • Mild or moderate skin reactions 15%
  • Any infection 11%
  • Upper respiratory infections 8%
  • Injection site reactions 26%
  • Non-upper respiratory infections 6%
  • Positive ana 6%
More Enbrel side effects »
  • Headache 5%
  • Common cold 3%
  • Dizziness 2%
  • Cough 1%
  • Back pain 1%
  • High blood pressure 3%
  • Indigestion 2%
  • Urinary tract infection 1%
  • Rash 1%
  • Pain in extremity 1%
More Orencia side effects »

We haven’t found good data for Arava side effects.

FDA side effect reports for Arava »
  • Headache 3%
  • High blood pressure 1%
  • Bronchitis (airway inflammation) 1%
  • Rash 3%
  • Alt increase (liver test change) 2%
  • Upper abdominal pain 1%
  • Mouth sores 1%
More Actemra side effects »
  • Elevated liver function tests 15%
  • Nausea/vomiting 10%
  • Mouth and lip swelling 10%
  • Thrombocytopenia 10%
  • Rash/pruritus/dermatitis 3%
  • Diarrhea 3%
  • Hair loss or baldness 3%
  • Low white blood cells 3%
  • Low blood cell count 3%
  • Dizziness 3%
More Methotrexate side effects »
  • Infections 11%
  • Infusion reaction 13%
More Remicade side effects »
How it works
PlaquenilRituxanHumiraCimziaEnbrelOrenciaAravaActemraMethotrexateRemicade
Plaquenil (Hydroxychloroquine) is called a DMARD, a disease-modifying antirheumatic drug. It prevents your body from activating cells that cause inflammation.Rituxan (Rituximab) is a monoclonal antibody. It targets a specific protein on white blood cells that makes it easier for your immune system to find and destroy cancerous cells. It also relieves symptoms and slows the progression of Rheumatoid Arthritis.Humira (adalimumab) is a TNF blocker which stops inflammation.Cimzia (Certolizumab) is a monoclonal antibody. It lowers inflammation in the body by blocking a protein called TNF (tumor necrosis factor).Enbrel (Etanercept) is a biologic response modifier. It works in the immune system to block a protein called TNF (tumor necrosis factor). Blocking TNF relieves symptoms and prevents disease progression.Orencia (Abatacept) is called a DMARD, a disease-modifying antirheumatic drug. It prevents your body from activating cells that cause inflammation.Coming soon.Actimmune (tocilizumab) is a biologic drug. It belongs to a group of drugs called DMARDs (disease-modifying anti-rheumatic drug). Actimmune (tocilizumab) stops IL-6 (interleukin-6), a protein that revs up the immune system, from working. Actimmune (tocilizumab) lowers inflammation, relieves symptoms, and prevents the disease from getting worse.Otrexup (Methotrexate) is an anti-cancer and immunosuppressive medication that treats forms of cancer, arthritis, and psoriasis. For cancer, it helps your body destroy cancer cells by blocking building blocks that cancer cells need to grow. For rheumatoid arthritis and psoriasis, it lowers the body's normal immune response and prevents the body from attacking itself.Remicade (Infliximab) is a biologic response modifier. It works in the immune system to block a protein called TNF (tumor necrosis factor). Blocking TNF relieves symptoms and prevents disease progression.
Type of medication
PlaquenilRituxanHumiraCimziaEnbrelOrenciaAravaActemraMethotrexateRemicade
Prescription only
Prescription only
Prescription only
Prescription only
Prescription only
Prescription only
Prescription only
Prescription only
Prescription only
Available as
PlaquenilRituxanHumiraCimziaEnbrelOrenciaAravaActemraMethotrexateRemicade
  • Pill
  • Infusion (iv)
  • Injection
  • Injection
  • Injection
  • Injection
  • Pill
  • Infusion
  • Injection
  • Pill
  • Injection
  • Injection
Used for
PlaquenilRituxanHumiraCimziaEnbrelOrenciaAravaActemraMethotrexateRemicade
  • Rheumatoid Arthritis
  • Rheumatoid Arthritis Moderate To Severe
Risk factors for serious side effects
PlaquenilRituxanHumiraCimziaEnbrelOrenciaAravaActemraMethotrexateRemicade
      • Children
      • Women of childbearing age
      • Taking Plaquenil (Hydroxychloroquine) in higher than recommended doses
      • Kidney disease
      • Total dose greater than 200 grams
      • Current problems with vision
      • Taking with alcohol
      • Taking other medicines that make you less alert
      Detailed Plaquenil (hydroxychloroquine) risks & warnings »
        • Taking other immunosuppressant drugs
        • Age 60 or older
        • Weak immune system
        • Taking Rituxan (Rituximab) with immunosuppressant drugs (if using for RA)
        • Taking Rituxan (Rituximab) with chemotherapy (if using for NHL or CLL
        • Stem cell transplant
          • Taking Rituxan (Rituximab) for Non-Hodgkin's Lymphoma (NHL)
          • Rapidly growing tumors
          • History of heart problems
          • Drug interactions
          • Start of therapy with Rituxan (Rituximab)
            Detailed Rituxan (rituximab) risks & warnings »
            • Taking other immunosuppressant medications such as Kineret or Orencia
            • Age 65 or older
            • Active, chronic, or recurrent infection
            • Comorbidities
            • Taking other immunosuppressant medications, such as azathiprine or 6-mercaptopurine, at the same time as Humira (adalimumab)
            • History of malignancy
            • Adolescent age
            • COPD with significant smoking history
              • History of heart failure
              • Preexisting or recently acquired neurologic condition
                Detailed Humira (adalimumab) risks & warnings »
                • Medications that lower immune system function
                • Younger age
                    • History of heart failure
                      Detailed Cimzia (certolizumab) risks & warnings »
                        • History of heart failure
                        • Taking other immunosuppressant drugs
                        • Age 60 or older
                        • Taking other immunosuppressant drugs
                        • History of malignancy
                        • History of neurologic condition
                          Detailed Enbrel (etanercept) risks & warnings »
                                • Taking immunosuppressive medications
                                • History of repeat infections
                                • Adults with rheumatoid arthritis taking TNF inhibitors
                                Detailed Orencia (abatacept) risks & warnings »
                                Coming soon.
                                • Diabetes, HIV, or other medical conditions that cause a weak immune system
                                • Taking other immunosuppressant medications
                                • Had TB or were exposed to TB in the past
                                • History of diverticulitis
                                        Detailed Actimmune (tocilizumab) risks & warnings »
                                        • Women of childbearing age
                                        • Men of childbearing potential
                                          • Reduced kidney function
                                          • fluid in the abdomen (ascites)
                                          • fluid in the lungs (pleural effusion)
                                          • Long-term use
                                          • Psoriasis
                                            • Taking Otrexup (Methotrexate) with high-dose NSAIDs
                                              • Taking Otrexup (Methotrexate) to treat cancer
                                              • Rapidly growing tumors
                                              Detailed Otrexup (methotrexate) risks & warnings »
                                                • History of heart failure
                                                • Taking other immunosuppressant drugs
                                                • Age 60 or older
                                                • Taking other immunosuppressant drugs
                                                • History of malignancy
                                                • History of neurologic condition
                                                    Detailed Remicade (infliximab) risks & warnings »
                                                    Pregnancy

                                                    The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

                                                    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

                                                    Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

                                                    Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

                                                    Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

                                                    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

                                                    Research studies with real people or animals found harmful effects on unborn babies. If you’re pregnant, the risks to your unborn baby outweigh the benefits.

                                                    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

                                                    Research studies with real people or animals found harmful effects on unborn babies. If you’re pregnant, the risks to your unborn baby outweigh the benefits.

                                                    Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

                                                    Interactions
                                                    PlaquenilRituxanHumiraCimziaEnbrelOrenciaAravaActemraMethotrexateRemicade
                                                    • Certain medications can interact with Plaquenil (Hydroxychloroquine), so to be safe, tell your doctor about other medications and supplements you may be taking.
                                                    No interactions related info.No interactions related info.No interactions related info.No interactions related info.No interactions related info.No interactions related info.No interactions related info.No interactions related info.No interactions related info.
                                                    Alcohol
                                                    PlaquenilRituxanHumiraCimziaEnbrelOrenciaAravaActemraMethotrexateRemicade
                                                    • Stay away from alcohol while taking Plaquenil (Hydroxychloroquine).
                                                    No alcohol related info.No alcohol related info.No alcohol related info.No alcohol related info.No alcohol related info.No alcohol related info.No alcohol related info.
                                                    • You have to avoid alcohol and being in the sun too long.
                                                    • Don't use alcohol, NSAIDs (anti-inflammatory medications), or stay in the sun too long.
                                                    No alcohol related info.
                                                    Kidneys and liver
                                                    PlaquenilRituxanHumiraCimziaEnbrelOrenciaAravaActemraMethotrexateRemicade
                                                    No kidneys and liver related info.
                                                    • Discuss with your doctor the serious heart, kidney, liver, or stomach problems that can happen while on Rituxan (Rituximab).
                                                    No kidneys and liver related info.No kidneys and liver related info.No kidneys and liver related info.No kidneys and liver related info.No kidneys and liver related info.
                                                    • This drug may not be the best choice if you have liver problems.
                                                    No kidneys and liver related info.No kidneys and liver related info.
                                                    Pain
                                                    PlaquenilRituxanHumiraCimziaEnbrelOrenciaAravaActemraMethotrexateRemicade
                                                    No pain related info.No pain related info.No pain related info.No pain related info.No pain related info.No pain related info.No pain related info.
                                                    • In studies, Actimmune (tocilizumab) lowered joint pain and slowed down joint damage better than a placebo in people who didn't have earlier success with methotrexate.
                                                    • Actimmune (tocilizumab) makes it harder for your immune system to fight infections. It increases the risk of serious or life-threatening infections, including TB (tuberculosis). Let your doctor know if you have a fever, cough, red or painful skin sores, stomach pain, or pain when you urinate. You'll need to have a TB (tuberculosis) test before starting Actimmune (tocilizumab).
                                                    No pain related info.No pain related info.
                                                    Weight
                                                    PlaquenilRituxanHumiraCimziaEnbrelOrenciaAravaActemraMethotrexateRemicade
                                                    No weight related info.No weight related info.No weight related info.No weight related info.No weight related info.No weight related info.No weight related info.No weight related info.No weight related info.
                                                    • Although rare, Remicade (Infliximab) can cause serious liver injury. You'll need to have your liver enzymes tested regularly. If liver enzymes are significantly elevated and you have appetite/weight loss, stomach discomfort, vomiting, and notice dark urine, yellowing of skin/eyes, change in stool color, and skin rash you should stop treatment with Remicade (Infliximab) until you can be completely assessed,
                                                    Upsides and benefits
                                                    PlaquenilRituxanHumiraCimziaEnbrelOrenciaAravaActemraMethotrexateRemicade
                                                    • Plaquenil (Hydroxychloroquine) has been shown to improve physical function in up to 80% of patients.
                                                    • Plaquenil (Hydroxychloroquine) and similar DMARD medications help minimize joint damage, decrease symptoms and lessen future complications.
                                                    • Plaquenil (Hydroxychloroquine) is an excellent choice for people who have difficulty tolerating newer biologic medications.
                                                    • A generic form of Plaquenil (Hydroxychloroquine) is available.
                                                    • Treats leukemia, lymphoma, and blood vessel inflammation.
                                                    • Also treats moderate to severe rheumatoid arthritis that hasn't responded to anti-TNF treatment (but you'll need to take methotrexate too).
                                                    • The chance of having a reaction to the infusion is highest during your first dose, but the risk decreases each time you get Rituxan (Rituximab). It usually happens within 30 minutes to 2 hours after starting the infusion.
                                                    • Rituxan (Rituximab) is a targeted therapy that works differently than chemotherapy. Both work well when they're taken together, especially when treating CLL and NHL.
                                                    • Humira (adalimumab) is effective in reducing symptoms in all of its approved indications.
                                                    • You can give yourself Humira (adalimumab) on your own at home rather than visiting a clinic or hospital.
                                                    • Humira (adalimumab) treats many different autoimmune conditions.
                                                    • Available in a single-use pen (Humira Pen) that may be more convenient and easier for some people to use.
                                                    • In studies, people with RA (rheumatoid arthritis) taking methotrexate had improved symptoms when Cimzia (Certolizumab) was added to methotrexate.
                                                    • Cimzia (Certolizumab) is as effective as other similar medicines for Crohn's disease. It can be an option for people taking other RA medications that have too many side effects of don't work anymore.
                                                    • Cimzia (Certolizumab) lasts longer in the body than other RA medications, letting it work longer.
                                                    • Available in a prefilled syringe. This can make it easier to give yourself the injection.
                                                    • Treats certain types of arthritis conditions caused by an overactive immune system.
                                                    • Enbrel is the first biologic approved for moderate to severe rheumatoid arthritis.
                                                    • It has an established safety profile for treatment of rheumatoid arthritis (RA).
                                                    • Available as a single-use syringe and SureClick auto-injector pen which may be more convenient and easier for some people to use.
                                                    • People taking Enbrel for rheumatoid arthritis showed significant improvement and were able to reduce the dose or stop immunosuppressant medicines.
                                                    • Helps minimize joint damage, lowers symptoms, and prevents future problems.
                                                    • In a 2-year study that used IV Orencia (Abatacept) with methotrexate, more than half of the people had remission and the majority felt significantly better.
                                                    • People taking [name-common] had no new joint damage after two years.
                                                    • Taking Orencia (Abatacept) allows RA patients to use less prednisone, a steroid that has many side effects.
                                                    • Orencia (Abatacept) can be used without other medications for RA.
                                                    Coming soon
                                                    • In studies, Actimmune (tocilizumab) lowered joint pain and slowed down joint damage better than a placebo in people who didn't have earlier success with methotrexate.
                                                    • Actimmune (tocilizumab) can work for you even if methotrexate or other medications haven't improved your rheumatoid arthritis.
                                                    • Many people have only minor side effects, or none at all.
                                                    • Recommended as first line treatment for rheumatoid arthritis.
                                                    • Available as a generic medication. Comes as a tablet, an injection that you give yourself weekly, and as an infusion that you get in your doctor's office or at an infusion center.
                                                    • If you accidentally take too much, there's an antidote to help your body recover.
                                                    • Treats certain types of arthritis and gastrointestinal conditions caused by an overactive immune system.
                                                    • Remicade has almost two decades of clinical trial data and real-life experience with millions of people who have used it.
                                                    • Initial dosing to introduce Remicade to your body might be a hassle, but then you only need to take it every 6-8 weeks depending on your condition.
                                                    Downsides and risks
                                                    PlaquenilRituxanHumiraCimziaEnbrelOrenciaAravaActemraMethotrexateRemicade
                                                    • You will likely have to take additional medications like Methotrexate to keep your RA in control.
                                                    • In some people, small particles develop in the eyes, so you’ll have to get your eyes checked once per year.
                                                    • It can take up to 6 months before the full benefits of Plaquenil (Hydroxychloroquine) are felt.
                                                    • Many people have nausea, stomach cramps, and diarrhea when they first start taking Plaquenil (Hydroxychloroquine).
                                                    • Only your doctor or other trained medical staff can administer Rituxan (Rituximab), so you'll need to go into an office or clinic for every dose.
                                                    • Not the best choice if you have heart problems.
                                                    • Rituxan (Rituximab) can stay in your body for up to 6 months after you complete treatment. Men and women who are able to have children need to use birth control for up to one year after finishing Rituxan (Rituximab).
                                                    • Discuss with your doctor the serious heart, kidney, liver, or stomach problems that can happen while on Rituxan (Rituximab).
                                                    • Not first-choice treatment for rheumatoid arthritis.
                                                    • Humira (adalimumab) is an injection and not an oral medication.
                                                    • Humira (adalimumab) is expensive because there's no generic available yet.
                                                    • Humira (adalimumab) lowers your ability to fight infection and in some cases can cause serious life-threatening illness. The risk is greater if you take other drugs that lower your immune system, have an active infection, diabetes, or had tuberculosis (TB) in the past.
                                                    • You'll need to properly dispose of the needle, syringes, or Pen in a sharps container.
                                                    • Humira (adalimumab) needs to be refrigerated until you use it, so if you're traveling, you'll need to carry it in a cooler with an ice pack.
                                                    • Can lower your immune system's ability to fight infections. You can get serious infections such as TB (tuberculosis) and infections caused by viruses, fungi, or bacteria.
                                                    • Can have a higher risk for causing bladder infections, rash, and upper respiratory infections (cold or flu) compared to other similar medicines.
                                                    • Cimzia (Certolizumab) can increase the risk of lymphoma, leukemia, and other cancers.
                                                    • Requires routine tests to check for infections.
                                                    • Not a good choice if you have a history of heart failure, nervous system problems, or hepatitis B.
                                                    • There's no generic available and it can be very expensive.
                                                    • It's an injection.
                                                    • It's expensive because there's no generic available yet.
                                                    • Enbrel lowers your ability to fight infection and can cause serious life-threatening illness. The risk is greater if you take other drugs that lower your immune system, have an active infection, diabetes, or had tuberculosis (TB) in the past.
                                                    • You're first dose of Enbrel will need to be given at your doctor's office. If you decide not to self-inject and don't have someone to do it for you, you'll need to continue to see your doctor for each dose.
                                                    • You'll need to properly dispose of the needle, syringes, or Pen in a special (FDA-approved) sharps container.
                                                    • Because it needs to be refrigerated until you use it, if you're traveling, you'll need to carry it in a cooler with an ice pack.
                                                    • You'll have to get your blood tested regularly while taking Orencia (Abatacept).
                                                    • You'll probably have to take other medications to help treat your RA symptoms.
                                                    • Orencia (Abatacept) is pretty expensive.
                                                    • The IV infusion form of Orencia (Abatacept) can cause a reaction, which ranges from a slight itching or warm feeling to more serious complications like low blood pressure and chest pain.
                                                    • Because RA is chronic disease, you'll likely take Orencia (Abatacept) for many years.
                                                    Coming soon
                                                    • Since Actimmune (tocilizumab) calms down your immune system, it raises your risk of serious or possibly life-threatening infections, including TB (tuberculosis).
                                                    • Actimmune (tocilizumab) doesn't come in a pill form - it has to be used as an injection or infusion.
                                                    • You'll need to get blood tests done before and during your treatment to make sure no problems arise while taking Actimmune (tocilizumab).
                                                    • This drug may not be the best choice if you have liver problems.
                                                    • There is no generic form of the drug, so it can be expensive.
                                                    • You have to be on birth control for at least 2 to 3 months after you finish Otrexup (Methotrexate) since it can cause birth defects.
                                                    • You have to avoid alcohol and being in the sun too long.
                                                    • You'll have to get blood tests done if you're taking this long-term because it can cause harmful side effects.
                                                    • You have to get every dose through an IV infusion at your doctor's office.
                                                    • It's expensive because there's no generic available yet.
                                                    • Remicade has a higher risk of serious infusion-related side effects during or after it's given since it's injected right into your veins. Your doctor can prescribe medication before your dose that may lower this risk.
                                                    • Remicade lowers your ability to fight infection and can cause serious life-threatening illness. The risk is greater if you take other drugs that lower your immune system, have an active infection, diabetes, or had tuberculosis (TB) in the past.
                                                    • Not the best choice if you have heart failure.
                                                    • Talk to your baby's doctor if you're pregnant or breast-feeding. When women in a study took Remicade (Infliximab), the medicine was found in their breast milk 2 to 3 days after each dose, and in the baby's blood 6 months after they were born.
                                                    Tips from our pharmacists for people taking the medication
                                                    PlaquenilRituxanHumiraCimziaEnbrelOrenciaAravaActemraMethotrexateRemicade
                                                    • Don’t give up on Plaquenil (Hydroxychloroquine), it can take 2-4 months to take effect.
                                                    • Take Plaquenil (Hydroxychloroquine) with milk to help decrease nausea.
                                                    • If you have difficulty swallowing Plaquenil (Hydroxychloroquine), you can crush it, and mix it in jam or jelly.
                                                    • While taking Plaquenil (Hydroxychloroquine) it is important to wear sunglasses in bright light to protect your eyes from damage. When you can’t avoid sunlight, be sure to use sunscreen, put on a long-sleeved shirt, pants, and a hat.
                                                    • Stay away from alcohol while taking Plaquenil (Hydroxychloroquine).
                                                    • Certain medications can interact with Plaquenil (Hydroxychloroquine), so to be safe, tell your doctor about other medications and supplements you may be taking.
                                                    • Rituxan (Rituximab) is given as an IV infusion by trained medical staff in a clinic or hospital.
                                                    • You'll need to be monitored in the clinic in case you have a serious or life-threatening reaction during the infusion, but you can take other medications that'll lower your risk of this happening.
                                                    • It's very important that you read the Medication Guide before you start taking Rituxan (Rituximab).
                                                    • Rituxan (Rituximab) lowers your immune system's ability to fight infections, so it's important to let your doctor know if you notice a fever, a cough that doesn't go away, or flu-like symptoms.
                                                    • Use effective birth control while you're taking Rituxan (Rituximab) and for 12 months after you finish treatment.
                                                    • Don't get live vaccines while you're taking Rituxan (Rituximab).
                                                    • Humira (adalimumab) is a medication that's injected under the skin. Your doctor can give you your first dose, then you can inject yourself at home once you feel comfortable doing so on your own.
                                                    • Humira (adalimumab) lowers your ability to fight infections, so it's important to let your doctor know if you have a fever, cough, or flu-like symptoms.
                                                    • Tell your doctor if you have an allergy to latex since the syringe needle cover has latex in it.
                                                    • Each time you use Humira (adalimumab), it's important to rotate the sites you chose to inject it in. Don't inject Humira (adalimumab) into skin that's red, bruised, or irritated.
                                                    • As with all injection medicines, store securely away from children and throw away used syringes in an FDA-approved sharps disposal container, and not in the trash.
                                                    • Cimzia (Certolizumab) is a medicine that's injected just under the skin (subcutaneous). It can be given in your doctor's office or you can do it yourself at home.
                                                    • It can take multiple doses before you start to see any effects, so don't change your dose without talking to your doctor.
                                                    • Tell your doctor if you have night sweats, persistent fever, fatigue, weight loss, or swollen lymph nodes.
                                                    • You'll need to have a TB (tuberculosis) test before you start Cimzia (Certolizumab) and periodically during treatment.
                                                    • Don't get any live vaccines while you're taking Cimzia (Certolizumab) since they may not work as well. Wait at least 3 months after you've stopped taking Cimzia (Certolizumab) before getting a live vaccine.
                                                    • Enbrel (Etanercept) is available as a single-use prefilled syringe, single-use prefilled SureClick Autoinjector, and multiple-use vial. You and your doctor can discuss which is best for you.
                                                    • The autoinjector can be stored at room temperature for up to 14 days and can't be refrigerated again.
                                                    • Enbrel (Etanercept) is a medication that's injected under the skin (subcutaneous). Your doctor can give you your first dose, then let you self-inject it once so you learn how to do it correctly.
                                                    • Enbrel (Etanercept) lowers the your immune system's ability to fight infections, so it's important to let your doctor know if you come down with a fever, cough, or notice flu-like symptoms.
                                                    • You'll need to have a TB test before you start using Enbrel (Etanercept).
                                                    • Tell your doctor if you have an allergy to latex since the syringe needle cover has latex in it.
                                                    • Don't inject Enbrel (Etanercept) into skin that's red, bruised, or irritated. Rotate your injection areas to avoid skin reactions.
                                                    • As with all injection medicines, store away from children and throw used syringes away in a protective container, and not in the trash.
                                                    • Keep the Orencia (Abatacept) self-injection refrigerated, but let it rest at room temperature for 30 to 60 minutes before using it.
                                                    • Each time you use Orencia (Abatacept), be sure to rotate the sites you chose to inject it in. Don't inject it where your skin is tender, bruised, red, or scaly.
                                                    • If you decide to go with the IV version of Orencia (Abatacept), you will only need to get infusions once a month. The self-injections however need to be taken once a week.
                                                    • If you get the IV infusion, stay hydrated, try to relax, and ask your nurse to apply dry heat (instant warm packs) to your arm to help find your good veins.
                                                    Coming soon
                                                    • It can take between 2 weeks and 3 months to start working.
                                                    • Even after your symptoms begin to improve, it is important to keep taking Actimmune (tocilizumab) to prevent further damage to your joints.
                                                    • Actimmune (tocilizumab) is available as an infusion (given at a doctor's office or an infusion center) or as an injection (given to yourself at home). Discuss which is best for you with your doctor.
                                                    • If you're using Actimmune (tocilizumab) at home, rotate your injection areas to avoid skin reactions. Don't give yourself an injection where your skin is red, bruised, or irritated.
                                                    • Keep Actimmune (tocilizumab) refrigerated, but let it warm up to room temperature for 30 to 60 minutes before using it.
                                                    • Don't use alcohol, NSAIDs (anti-inflammatory medications), or stay in the sun too long.
                                                    • Use birth control and avoid pregnancy for at least 2 months (for women) and 3 months (for men) after you finish Otrexup (Methotrexate).
                                                    • Drink plenty of liquids to stay hydrated while taking this.
                                                    • Take the medication exactly as your doctor or pharmacist tells you. Call your doctor or pharmacist if you're confused.
                                                    • Remicade (Infliximab) is a medication that's given as an infusion at your doctor's office or clinic.
                                                    • It's very important to read the patient Medication Guide when you first start using Remicade (Infliximab).
                                                    • It's possible to get an allergic reaction to Remicade (Infliximab) either immediately during the treatment or a several days after stopping it. Your doctor can give you medicines that'll lower this risk.
                                                    • You'll need to have a TB test before you start taking Remicade (Infliximab) and periodically during treatment.
                                                    • Remicade (Infliximab) lowers your immune system's ability to fight infections, so it's important to let your doctor know if you notice a fever, cough, or flu-like symptoms. Children seem to get more infections than adults, so keep a close eye on them.
                                                    • If you have a young child, let their doctor know if you were on Remicade (Infliximab) while pregnant or nursing. It can increase their risk of infections for several months after your last dose and can delay their vaccine schedule.
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