Prescription onlyClass: Cardiovascular

Pradaxa Alternatives

(dabigatran)

Prescription onlyClass: Cardiovascular
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Compare Pradaxa (dabigatran) to alternatives

These medications are comparable to Pradaxa (dabigatran) or used for similar purposes.

Pradaxa
(dabigatran)

Aggrenox
(aspirin / dipyridamole)

Coumadin
(warfarin)

Xarelto
(rivaroxaban)

heparin

Prevents blood clots. Pradaxa (Dabigatran) is a good medication for preventing blood clots. It doesn't require regular blood tests or changing doses often. It can be expensive and there's no way to reverse the medication's effects.Prevents blood clots that can cause a stroke. Aggrenox (Aspirin / Dipyridamole) prevents blood clots and stroke, but cheaper options are available that work just as well.Prevents blood clots. Coumadin (warfarin) is a cheap and effective medicine that prevents new blood clots. It requires regular blood tests and you'll need to eat, exercise, and take your medicines consistently.Prevents blood clots. Xarelto (rivaroxaban) is a good medication for preventing blood clots. It doesn't require regular blood tests or changing doses often. However, it can be expensive and there's no way to reverse the medication's effects.Prevents blood clots. Heparin is a good anticoagulant that prevents blood clots. However, you'll need to get frequent blood tests to make sure it's working well.
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Coupons for Pradaxa
Best available price for 1 (60 capsules of 150mg) dose pack of pradaxa
Reviews & ratings
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Not enough reviews for this treatment. Help someone out, leave a review!

Have you used Pradaxa (dabigatran)?
Worth itNot sureNot worth it

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Have you used Aggrenox (aspirin / dipyridamole)?
Worth itNot sureNot worth it
Reviews for Coumadin
61%
-11% worse vs. Pradaxa
54%
+13% better vs. Pradaxa
21%
+21% better vs. Pradaxa
513 reviews
Have you used Coumadin (warfarin)?
Worth itNot sureNot worth it
Reviews for Xarelto
45%
+5% better vs. Pradaxa
45%
+22% better vs. Pradaxa
9%
+9% better vs. Pradaxa
Have you used Xarelto (rivaroxaban)?
Worth itNot sureNot worth it

Not enough reviews for this treatment. Help someone out, leave a review!

Have you used Heparin?
Worth itNot sureNot worth it
Side effects
PradaxaAggrenoxCoumadinXareltoHeparin
  • Gi side effect 35%
  • Any side effect 21%
  • Any bleed 20%
  • Indigestion 8%
  • Major gastrointestinal bleed 6%
  • Gi bleed 3%
  • Major bleed 3%
  • Gastritis-like symptoms 3%
  • Gastrointestinal bleed 2%
  • Life-threatening bleed 2%
More Pradaxa side effects »
  • Headache 10%
  • Indigestion 3%
  • Abdominal pain 6%
  • Nausea 6%
  • Diarrhea 3%
  • Vomiting 1%
  • Joint pain 1%
More Aggrenox side effects »

The Coumadin FDA package insert doesn’t have numbers about how common side effects are.

More about Coumadin side effects »
  • Major bleeding needing transfusion 4%
  • Bleeding in the stomach & intestines 2%
  • Complaints of bleeding 28%
  • Clinically relevant but not major bleeding 9%
  • Back pain 3%
  • Upper abdominal pain 2%
  • Joint arthritis 1%
  • Any bleeding event after hip or knee replacement surgery 6%
  • Any side effect causing stopping of xarelto (rivaroxaban) 4%
  • Wound drainage 3%
More Xarelto side effects »

We haven’t found good data for Heparin side effects.

FDA side effect reports for Heparin »
How it works
PradaxaAggrenoxCoumadinXareltoHeparin
Pradaxa (Dabigatran) is an anticoagulant that stops the formation of blood clots.Aggrenox (Aspirin / Dipyridamole) is an antiplatelet blood thinner. It is a combination medication with two ingredients, aspirin and dipyridamole. Both make it harder for your body to form blood clots.Coumadin (warfarin) prevents blood clots from forming. It doesn't break up clots that already exist. It can only stop new ones from forming or old ones from getting bigger.Xarelto (rivaroxaban) is an anticoagulant that stops blood clots from forming.Heparin is an anticoagulant that binds with proteins and platelets to stop blood clots from being made and traveling to the brain, heart, and lungs.
Type of medication
PradaxaAggrenoxCoumadinXareltoHeparin
Prescription onlyPrescription onlyPrescription onlyPrescription onlyPrescription only
Available as
PradaxaAggrenoxCoumadinXareltoHeparin
  • Pill
  • Pill
  • Pill
  • Pill
  • Injection
Used for
PradaxaAggrenoxCoumadinXareltoHeparin
Risk factors for serious side effects
PradaxaAggrenoxCoumadinXareltoHeparin
  • Stopping Pradaxa (Dabigatran) too soon
  • Spinal tap
  • Anesthesia along the spine (epidural anesthesia)
  • Taking NSAIDs, aspirin, or other blood-thinning medicines
  • Drug interactions
Detailed Pradaxa (dabigatran) risks & warnings »
  • Children 18 years or younger recovering from viral infections
  • History of stomach bleeding or ulcers
  • Age 60 or older
  • Also taking other blood thinners
  • Drinking 3 or more alcoholic drinks a day
Detailed Aggrenox (aspirin / dipyridamole) risks & warnings »
  • Coumadin (warfarin) dose too high
  • Age greater than 65 year
  • History of stomach bleeding
  • High blood pressure
  • Kidney or liver problems
Detailed Coumadin (warfarin) risks & warnings »
  • Stopping Xarelto (rivaroxaban) too soon
  • Artificial heart valve
  • Spinal puncture (spinal tap)
  • Getting anesthesia in the spine (epidural anesthesia)
  • History of bleeding problems
Detailed Xarelto (rivaroxaban) risks & warnings »
  • History of bleeding problems
  • Severe high blood pressure
  • Older age
  • Heparin-induced thrombocytopenia
Detailed Heparin risks & warnings »
Pregnancy

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Research studies with real people or animals found harmful effects on unborn babies. If you’re pregnant, the risks to your unborn baby outweigh the benefits.

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Interactions
PradaxaAggrenoxCoumadinXareltoHeparin
No interactions related info.No interactions related info.
  • A lot of other drugs and supplements interact with Coumadin (warfarin), so you'll need to check with your doctor or pharmacist before starting any new medicines.
  • Coumadin (warfarin) interacts with many drugs and supplements. This can increase your risk of bleeding or of developing a new blood clot. If you start a new medication or change your diet, let your doctor know so they can change your dose if necessary.
  • Xarelto (rivaroxaban) doesn't interact with as many types of food as other blood thinners like warfarin (Coumadin).
No interactions related info.
Food
PradaxaAggrenoxCoumadinXareltoHeparin
No food related info.
  • Do not crush or chew capsules. Can take with or without food.
No food related info.
  • Like all blood thinners, it will take a little longer for your blood to clot if you start bleeding while you're taking Xarelto (rivaroxaban). Call your doctor if you notice bleeding that won't stop, a bruise that won't go away or gets worse, pink or brown urine, bright red or dark tarry stool, nose bleeds, or if you start coughing up blood.
No food related info.
Kidneys and liver
PradaxaAggrenoxCoumadinXareltoHeparin
No kidneys and liver related info.
  • Do not use Aggrenox (Aspirin / Dipyridamole) if you have severe kidney disease.
No kidneys and liver related info.
  • Xarelto (rivaroxaban) is processed by the kidney and liver. If you have kidney or liver problems, talk to your doctor about possibly switching to a different medicine to avoid other side effects.
No kidneys and liver related info.
Upsides and benefits
PradaxaAggrenoxCoumadinXareltoHeparin
  • Clinical studies have shown that the risk of stroke and blood clots is lower than with warfarin, another popular "blood thinner" (anticoagulant).
  • Doesn't require regular blood tests or frequent dose changes.
  • In studies comparing Pradaxa (Dabigatran) to other "blood thinners", it worked just as well in preventing strokes and was better in lowering the risk of bleeding.
  • This helps to prevent strokes for people who had a stroke or TIA (transient ischemic attack) before.
  • In clinical studies, Aggrenox (Aspirin / Dipyridamole) lowered the chance of another stroke for a person with a previous stroke or mini-stroke (TIA) by 36%.
  • Works better than either aspirin or dipyridamole alone to prevent strokes.
  • Works as well as Plavix (clopidogrel), another antiplatelet medication, to prevent stroke.
  • Coumadin (warfarin) is available as a generic, so it should be less expensive than the brand version.
  • In case you start bleeding too much while using Coumadin (warfarin), your doctor can give you another drug that reverses Coumadin (warfarin)'s effects.
  • Coumadin (warfarin) comes in numerous strengths.
  • Coumadin (warfarin) has been around for a long time and is one of the most commonly used 'blood thinner' medicines.
  • Studies show that Xarelto (rivaroxaban) works just as well as other blood thinners (anticoagulants) in preventing strokes and stopping clots from froming.
  • Xarelto (rivaroxaban) doesn't require regular blood tests or frequent dose changes.
  • Xarelto (rivaroxaban) doesn't interact with as many types of food as other blood thinners like warfarin (Coumadin).
  • Safe to use in pregnancy and if you're breast feeding.
  • There are other medications that can help stop unexpected bleeding while taking Heparin.
  • Available as a generic medication.
  • Usually used in the hospital, but can be given at home too.
Downsides and risks
PradaxaAggrenoxCoumadinXareltoHeparin
  • Not available as generic.
  • There are no antidotes to stop bleeding caused by taking too much Pradaxa (Dabigatran).
  • Can't take during pregnancy.
  • Raises your risk for bleeding and bruising.
  • Has to be taken twice a day unlike Plavix that only has to be taken once daily.
  • Can be more expensive than other alternatives that are available as a generic.
  • Can't be used by people with an aspirin allergy, or a history of stomach ulcers.
  • Raises your risk of bleeding and bruising.
  • Requires regular blood work, such as an INR, to make sure Coumadin (warfarin) is working correctly.
  • Your daily dose of Coumadin (warfarin) can change if you change your diet, exercise patterns, or use of alcohol.
  • A lot of other drugs and supplements interact with Coumadin (warfarin), so you'll need to check with your doctor or pharmacist before starting any new medicines.
  • Xarelto (rivaroxaban) can increase your risk of bleeding, so call your doctor right away if you see blood in your spit, urine, or stool (look for black, tarry stools or bright red blood).
  • Xarelto (rivaroxaban) isn't available as a generic medication.
  • There are no antidotes to stop bleeding caused by taking too much Xarelto (rivaroxaban).
  • You can't take Xarelto (rivaroxaban) if you are pregnant.
  • You'll need to get labs/blood draws done on a regular basis to make sure the drug is working and to make sure you don't get unexpected side effects.
  • You can be at higher risk for bleeding or clotting while taking Heparin compared to other anticoagulants.
Tips from our pharmacists for people taking the medication
PradaxaAggrenoxCoumadinXareltoHeparin
  • Pradaxa (Dabigatran) is an anticoagulant, so it's important not to miss a dose. Don't stop taking this medication without talking to your doctor first.
  • When taking Pradaxa (Dabigatran), you can bleed more easily, so use a soft toothbrush and an electric razor to avoid cutting yourself.
  • Take this exactly as your doctor or pharmacist tells you to.
  • Take with a full glass of water. Swallow the capsule whole. Don't chew, break, or open the capsule.
  • Take twice daily.
  • Do not crush or chew capsules. Can take with or without food.
  • Aggrenox (Aspirin / Dipyridamole) can cause unexpected bleeding or bruising.
  • Don't take if you're allergic to aspirin.
  • Headache is a common side effect, but it often goes away after the first week of use.
  • Prevents clots from forming or getting bigger. It doesn't break up clots that already exist.
  • Take Coumadin (warfarin) exactly as your doctor tells you.
  • Once you're taking Coumadin (warfarin), it'll take longer for your body to heal if you get cut or bruised. Call your doctor if you notice any unusual bleeding or bruising.
  • Carry a list of your medications with you or wear a medical bracelet that says you're on Coumadin (warfarin) in case you have a medical emergency.
  • Your doctor will check your blood regularly for the first few months that you're taking Coumadin (warfarin).
  • To get the best results, don't fall behind on taking your other medicines and eat the same amount of vegetables each day.
  • Xarelto (rivaroxaban) prevents blood from clotting, so it's important not to miss a dose. If you miss your daily dose, take it as soon as you remember that day. Just don't take two doses close to each other.
  • If you completely forget to take a dose, call your doctor right away.
  • When taking Xarelto (rivaroxaban), you can bleed more easily, so use a soft toothbrush and an electric razor to avoid cutting yourself.
  • You can crush the pills and mix it with a spoonful of applesauce, but make sure to eat some food and drink a glass of water right away.
  • Make sure to change where you inject Heparin every time.
  • Don't take aspirin or other anti-inflammatory medications without talking to your doctor first.
  • You will have to do regular blood draws or labs to make sure that Heparin is working for you.
Learn more
More about PradaxaSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Pradaxa (dabigatran)?
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More about AggrenoxSide effectsReviews & ratingsFDA package insert
Have you used Aggrenox (aspirin / dipyridamole)?
Worth itNot sureNot worth it
More about CoumadinSide effectsReviews & ratingsFDA package insert
Have you used Coumadin (warfarin)?
Worth itNot sureNot worth it
More about XareltoSide effectsReviews & ratingsFDA package insert
Have you used Xarelto (rivaroxaban)?
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More about HeparinSide effectsReviews & ratingsFDA package insert
Have you used Heparin?
Worth itNot sureNot worth it