Prescription onlyLower-cost generic available

Minipress

(Prazosin)

  • Pill
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Lowers blood pressure and makes it easier to urinate.

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Prescription onlyLower-cost generic available

Our pharmacists’ bottom line

Prazosin is used mostly to make urination easier for men with an enlarged prostate, but it can cause dizziness.

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  • Can be added to other blood pressure-lowering medicines if you need additional blood pressure control.
  • Makes urination easier in men with an enlarged prostate.
  • Helps people with PTSD get better sleep with fewer, less-intense nightmares.
  • Not the best medicine to lower blood pressure by itself.
  • Likely to cause orthostatic hypotension. This means dizziness when you change positions (like standing up) because your blood pressure doesn't adjust quickly enough.
  • Not preferred for people 65 years or older.

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Side effects for Minipress (Prazosin)

From clinical trials of Prazosin / High blood pressure ( 900)

  • DizzinessDizziness10% for Prazosin vs.0% for placebo
  • HeadacheHeadache8% for Prazosin vs.0% for placebo
  • DrowsinessDrowsiness8% for Prazosin vs.0% for placebo
  • Lack of energyLack of energy7% for Prazosin vs.0% for placebo
  • WeaknessWeakness7% for Prazosin vs.0% for placebo
  • Heart pounding or racing sensationHeart pounding or racing sensation5% for Prazosin vs.0% for placebo
  • NauseaNausea5% for Prazosin vs.0% for placebo

Manufacturers don’t say how common these side effects are

  • Blurred vision
  • Constipation
  • Diarrhea
  • Dry mouth
  • Fainting
  • Low mood disorder
  • Nasal congestion
  • Nervousness
  • Nosebleed
  • Omiting
  • Positional low blood pressure
  • Rash
  • Reddened sclera
  • Shortness of breath
  • Swelling due to excess fluid
  • Urinary frequency
  • Vertigo

What to expect when you take Minipress (Prazosin)

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Tips from our pharmacists
  • Check your blood pressure 1 week after starting this medicine, and tell your doctor if it hasn't improved.
  • Can cause drowsiness, headache, dizziness, and nausea.
  • Take with food or at bedtime to avoid side effects.
  • If side effects don't go away, talk to your doctor about alternatives.
  • Recheck your blood pressure 1 week after starting this medicine.

Risks and Warnings for Minipress (Prazosin)

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    • Higher risk if:
    • Age 65 years or older

    You can feel dizzy or fall from a sudden drop in blood pressure when you change positions, such as going from sitting to standing. This is called orthostatic hypotension. If you're sensitive to low blood pressure, change position slowly until your body is used to the medicine. If symptoms continues for more than a week, dose adjustment or a different medication may be needed.

Means that some groups have a high risk of experiencing this side effect

Tips from pharmacists and people taking Minipress (Prazosin)

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The FDA category for this medication is C. It is advised that you: Weigh risks vs. benefits
Pregnancy
Food
  • Tips from our pharmacists
  • Take with food or at bedtime to avoid side effects.
Sleep
  • Upsides and downsides from our pharmacists
  • Helps people with PTSD get better sleep with fewer, less-intense nightmares.
  • Tips from our pharmacists
  • Can cause drowsiness, headache, dizziness, and nausea.
  • Brought my BP into normal range, made it easier to urinate, and seems to have helped me go to sleep and sleep through the night without the excessive nervousness of PTSD.
    Age: 71
    Gender: Man
    Taken for: High blood pressure